Research Explorer

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Researcher

Wim Schelstraete

Awards & Distinctions

16 Results

2021

Enrofloxacin dose optimization for the treatment of colibacillosis in broiler chickens using a drinking behaviour pharmacokinetic model

Robin TemmermanLudovic PelligandWim SchelstraeteGunther AntonissenAn GarmynMathias Devreese

A1 Journal Article in ANTIBIOTICS-BASEL

Hepatic cytochrome P450 abundance and activity in the developing and adult Gottingen Minipig : Pivotal data for PBPK modeling

Laura BuyssensLaura De ClerckWim SchelstraeteMaarten DhaenensDieter DeforceMiriam AyusoChris Van GinnekenSteven Van Cruchten

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

2020

Comparative toxicokinetics of Fusarium mycotoxins in pigs and humans

Wim SchelstraeteMathias DevreeseSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

2019

Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective

Wim SchelstraeteLaura De ClerckElisabeth GovaertJoske MillecamMathias DevreeseDieter DeforceJan Van BocxlaerSiska Croubels

A1 Journal Article in SCIENTIFIC REPORTS

Impact of subacute exposure to T-2 toxin and zearalenone on the pharmacokinetics of midazolam as CYP3A probe drug in a porcine animal model : a pilot study

Wim SchelstraeteMathias DevreeseSiska Croubels

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Interactions between Fusarium mycotoxins and cytochrome P450 drug metabolizing enzymes in a porcine animal model

Wim SchelstraeteSiska CroubelsMathias Devreese

Resistance assessment and safeguarding the efficacy : dose optimalization of enrofloxacin for the treatment of colibacillosis in broilers

Robin TemmermanLudovic PelligandWim SchelstraeteGerty VanantwerpenMia VanrobaeysAn GarmynGunther AntonissenMathias Devreese

2018

Impact of T-2 toxin and zearalenone on the pharmacokinetics of midazolam as CYP3A probe drug in an in vivo porcine animal model

Wim SchelstraeteMathias DevreeseSiska Croubels

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : fact or fiction?

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : the added value of proteomics

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Maturation of hepatic cytochrome P450 enzymes in conventional pigs as model for preclinical paediatric drug research

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Storage stability study of porcine hepatic and intestinal cytochrome P450 isoenzymes by use of a newly developed and fully validated highly sensitive HPLC-MS/MS method

Wim SchelstraeteMathias DevreeseSiska Croubels

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The ontogeny of cytochrome P450 enzyme activity and protein abundance in conventional pigs in support of preclinical pediatric drug research

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

2017

Het gebruik van (acetyl)salicylzuur bij varkens

Wim SchelstraeteMathias DevreeseDominiek Maes

Editorial material

Impact of Fusarium mycotoxins on in vitro activity of major hepatic cytochrome P450 biotransformation enzymes in pigs

Wim SchelstraeteMathias DevreeseSiska Croubels

2016

Interaction between Fusarium mycotoxins and cytochrome P450 drug metabolizing enzymes/ABC drug transporters in a porcine animal model

Wim SchelstraeteMathias DevreeseJan Van BocxlaerSiska Croubels