Research Explorer

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Researcher

Tom Verhaeghe

Awards & Distinctions

14 Results

2017

Correlated positions in protein evolution and engineering

Jorick FranceusTom VerhaegheTom Desmet

A1 Journal Article in JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

2016

Converting bulk sugars into prebiotics : semirational design of a transglucosylase with controlled selectivity

Tom VerhaegheKarel De WinterMagali BerlandRob De VreeseMatthias D'hoogheBernard OffmannTom Desmet

A1 Journal Article in CHEMICAL COMMUNICATIONS

Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors

Rob De VreeseYves DepetterTom VerhaegheTom DesmetVeronick BenoyWanda HaeckLudo Van Den BoschMatthias D'hooghe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

2015

Creating space for large acceptors: rational biocatalyst design for resveratrol glycosylation in an aqueous system

Mareike Dirks-HofmeisterTom VerhaegheKarel De WinterTom Desmet

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2014

Biphasic catalysis with disaccharide phosphorylases: chemoenzymatic synthesis of α-D-glucosides using sucrose phosphorylase

Karel De WinterTom DesmetTim DevlamynckLisa Van RenterghemTom VerhaegheHelena PelantováVladimír KřenWim Soetaert

A1 Journal Article in ORGANIC PROCESS RESEARCH & DEVELOPMENT

Engineering the carbohydrate-binding site of Epa1p from Candida glabrata: generation of adhesin mutants with different carbohydrate specificity

Francesco S IelasiTom VerhaegheTom DesmetRonnie G Willaert

A1 Journal Article in GLYCOBIOLOGY

Improving the glycosylation potential of sucrose phosphorylase through enzyme engineering

Tom VerhaegheTom DesmetWim Soetaert

The quest for a thermostable sucrose phosphorylase reveals sucrose 6'-phosphate phosphorylase as a novel specificity

Tom VerhaegheDirk AertsMargo DiricksWim SoetaertTom Desmet

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

2013

Consensus engineering of sucrose phosphorylase: the outcome reflects the sequence input

Dirk AertsTom VerhaegheHenk-Jan JoostenGert VriendWim SoetaertTom Desmet

A1 Journal Article in BIOTECHNOLOGY AND BIOENGINEERING

Mapping the acceptor site of sucrose phosphorylase from Bifidobacterium adolescentis by alanine scanning

Tom VerhaegheMargo DiricksDirk AertsWim SoetaertTom Desmet

A1 Journal Article in JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A

Rob De VreeseTom VerhaegheTom DesmetMatthias D'hooghe

A1 Journal Article in CHEMICAL COMMUNICATIONS

Synthesis of 2-aminomethyl-4-phenyl-1-azabicyclo[2.2.1]heptanes via LiAlH4-induced reductive cyclization of 2-(4-chloro-2-cyano-2-phenylbutyl) aziridines and evaluation of their antimalarial activity

Matthias D'hoogheKarel VervischKarl W TörnroosTom VerhaegheTom DesmetCarmen LateganPeter J SmithKelly ChibaleNorbert De Kimpe

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2011

A constitutive expression system for high-throughput screening

Dirk AertsTom VerhaegheMarjan De MeyTom DesmetWim Soetaert

A1 Journal Article in ENGINEERING IN LIFE SCIENCES

Transglucosylation potential of six sucrose phosphorylases toward different classes of acceptors

Dirk AertsTom VerhaegheBart RomanChristian StevensTom DesmetWim Soetaert

A1 Journal Article in CARBOHYDRATE RESEARCH