Research Explorer

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Researcher

Tom Van Nieuwenhuysen

Awards & Distinctions

14 Results

2024

Strain-level characterization of foodborne pathogens without culture enrichment for outbreak investigation using shotgun metagenomics facilitated with nanopore adaptive sampling

Florence BuytaersBavo VerhaegenTom Van NieuwenhuysenNancy H. C. RoosensKevin VannesteKathleen MarchalSigrid C. J. De Keersmaecker

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

2022

Engraftment of allotransplanted tumor cells in adult rag2 mutant Xenopus tropicalis

Dieter TulkensDionysia DimitrakopoulouMarthe BoelensTom Van NieuwenhuysenSuzan DemuynckWendy ToussaintDavid CreytensPieter Van VlierbergheKris Vleminckx

A1 Journal Article in CANCERS

Identifying and characterizing EZH2 as a druggable dependency factor for desmoid tumors in a genetic Xenopus tropicalis model for Gardner's Syndrome

Thomas NaertDieter TulkensTom Van NieuwenhuysenJoanna PrzybylSuzan DemuynckMushriq Al-JazraweMatt van de RijnBenjamin AlmanKim De LeenheerPaul Coucke et al.

2021

CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping

Thomas NaertDieter TulkensTom Van NieuwenhuysenJoanna PrzybylSuzan DemuynckMatt van de RijnMushriq Al-JazraweBenjamin A. AlmanPaul CouckeKim De Leeneer et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2018

CRISPR/Cas9 mediated knockout of rcbtb1 in Xenopus tropicalis to model RCBTB1-associated retinal disease

Giulia AscariThomas NaertTom Van NieuwenhuysenMarjolein CarronSuzan DemuynckChris GuerinFrauke CoppietersKris VleminckxElfride De Baere

CRISPR/Cas9 mediated knockout of rcbtb1 in Xenopus tropicalis to model RCBTB1-associated retinal disease

Giulia AscariThomas NaertTom Van NieuwenhuysenSuzan DemuynckChris GuerinFrauke CoppietersKris VleminckxElfride De Baere

Targeted genome engineering in Xenopus using the transcription activator-like effector nuclease (TALEN) technology

Tom Van NieuwenhuysenKris Vleminckx

Bookchapter in Xenopus : methods and protocols

2017

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

Thomas NaertRobin ColpaertTom Van NieuwenhuysenDionysia DimitrakopoulouDavid CreytensKris Vleminckx

Modeling human disease in Xenopus tropicalis using programmable nucleases

Tom Van NieuwenhuysenKris Vleminckx

TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models

Thomas NaertTom Van NieuwenhuysenKris Vleminckx

A1 Journal Article in GENESIS

2016

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

Thomas NaertRobin ColpaertTom Van NieuwenhuysenDionysia DimitrakopoulouJ LJurgen HaustraeteAnnekatrien BoelWouter SteyaertTrees LepezDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

2015

TALEN mediated mutation of apc and β-catenin in Xenopus tropicalis as powerful models for Wnt driven cancer and Familial Adenomatous Polyposis (FAP)

Tom Van NieuwenhuysenThomas NaertDavid CreytensFrans Van RoyKris Vleminckx

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis

Tom Van NieuwenhuysenThomas NaertHong Tran ThiGriet Van ImschootSarah GeursEllen SandersDavid CreytensFrans Van RoyKris Vleminckx

A2 Journal Article in ONCOSCIENCE

2013

TLR2 activation causes no morbidity or cardiovascular failure, despite excessive systemic nitric oxide production

Anje CauwelsBenjamin VandendriesscheJennyfer BultinckBenedicte DescampsElke RoggeTom Van NieuwenhuysenMagdalena SipsChristian VanhovePeter Brouckaert

A1 Journal Article in CARDIOVASCULAR RESEARCH