Research Explorer

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Researcher

Tom Deroo

Awards & Distinctions

28 Results

2018

GC content of Early Metazoan genes and its impact on gene expression levels in mammalian cell lines

Ismail Sahin GülJens StaalPaco HulpiauEvi De KeuckelaereKai KammTom DerooEllen SandersKatrien StaesYasmine DriegeYvan Saeys et al.

A1 Journal Article in GENOME BIOLOGY AND EVOLUTION

2015

Alternative routes to induce naive pluripotency in human embryonic stem cells

Galbha DuggalSharat WarrierSabitri GhimireDorien BroekaertMargot Van der JeughtSylvie LiermanTom DerooLuc PeelmanAnn Van SoomMaria Cornelissen et al.

A1 Journal Article in STEM CELLS

Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation

Margot Van der JeughtJasin TaelmanGalbha DuggalSabitri GhimireSylvie LiermanSusana Marina Chuva de Sousa LopesDieter DeforceTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in CELLULAR REPROGRAMMING

Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneSabitri GhimireMado VandewoestyneYuechao LuJan GerrisRudy Van CosterTom DerooDieter DeforceStijn VansteelandtPetra De Sutter et al.

A1 Journal Article in CELL REPORTS

Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos

Sabitri GhimireBjörn HeindryckxMargot Van der JeughtJitesh NeupaneThomas O'LearySylvie LiermanWinnok De VosSusana Marina Chuva de Sousa LopesTom DerooPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2014

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianSylvie LiermanRudy Van CosterJan GerrisTom Deroo et al.

A1 Journal Article in HUMAN REPRODUCTION

Assessment of cellular heterogeneity in the level of mitochondrial DNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneBjörn HeindryckxMado VandewoestyneSabitri GhimireYuechao LuRudy Van CosterDieter DeforceTom DerooPetra De Sutter

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

Jitesh NeupaneMado VandewoestyneSabitri GhimireYuechao LuChen QianRudy Van CosterJan GerrisTom DerooDieter DeforcePetra De Sutter et al.

A1 Journal Article in MITOCHONDRION

Effect of ionomycin and calcium in the culture medium on the calcium releasing pattern of mouse oocytes and their subsequent embryonic development

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneChen QianWinnok De VosJP OzilTom DerooPetra De SutterBjörn Heindryckx

Inhibition of TGFß signaling supports embryonic stem cell derivation and the ground state of pluripotency in mouse

Sabitri GhimireBjörn HeindryckxJitesh NeupaneDieter DeforceTom DerooPetra De Sutter

Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilization

Dimitra NikiforakiFrauke Vanden MeerschautChen QianIlse De CrooYuechao LuTom DerooEtienne Van den AbbeelBjörn HeindryckxPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Sperm involved in recurrent partial hydatidiform moles cannot induce the normal pattern of calcium oscillations

Dimitra NikiforakiFrauke Vanden MeerschautStefanie De GheselleChen QianEtienne Van den AbbeelWinnok De VosTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in FERTILITY AND STERILITY

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtBjörn HeindryckxThomas O'LearyGalbha DuggalSabitri GhimireSylvie LiermanNadine Van RoySusana Marina Chuva de Sousa LopesTom DerooDieter Deforce et al.

A1 Journal Article in HUMAN REPRODUCTION

Use of pluripotent stem cells for reproductive medicine: are we there yet?

Galbha DuggalBjörn HeindryckxTom DerooPetra De Sutter

A1 Journal Article in VETERINARY QUARTERLY

2013

Analysis of calcium oscillations pattern triggered by human sperm showing failed or low fertilization

Björn HeindryckxDimitra NikiforakiLeen CaluwaertsFrauke Vanden MeerschautTom DerooPetra De Sutter

Evaluation of calcium machinery in a meiosis defect mouse model

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneWinnok De VosSylvie LiermanTom DerooBjörn HeindryckxPetra De Sutter

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential

Galbha DuggalBjörn HeindryckxSharat WarrierThomas O'LearyMargot Van der JeughtSylvie LiermanLiesbeth VossaertTom DerooDieter DeforceSusana Marina Chuva de Sousa Lopes et al.

A1 Journal Article in STEM CELLS AND DEVELOPMENT

Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxTom DerooYuechao LuSabitri GhimireSylvie LiermanChen QianDieter DeforcePetra De Sutter

Regulation of inositol 1,4,5-trisphosphate receptor during human oocyte maturation and fertilization

Dimitra NikiforakiLiesbeth VossaertFrauke Vanden MeerschautChen QianYuechao LuJ ParysWinnok De VosDieter DeforceTom DerooEtienne Van den Abbeel et al.

2010

Direct control of Hoxd1 and Irx3 expression by Wnt/β-catenin signaling during anteroposterior patterning of the neural axis in Xenopus

Sylvie JanssensTinneke DenaeyerTom DerooFrans Van RoyKris Vleminckx

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

2005

Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets

JI PARKSW KIMJP LYONSH JITT NGUYENKC CHOMC BARTONTom DerooKris VleminckxPD MCCREA

A1 Journal Article in DEVELOPMENTAL CELL

2004

Global inhibition of Lef1/Tcf-dependent Wnt signaling at its nuclear end point abrogates development in transgenic Xenopus embryos

Tom DerooTinneke DenayerFrans Van RoyKris Vleminckx

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

A universal influenza A vaccine based on the extracellular domain of the M2 protein.

Sabine NeirynckTom DerooXavier SaelensP VANLANDSCHOOTWilly Min JouWalther Fiers

A1 Journal Article in NATURE MEDICINE

1998

Evaluation of recombinant A/Victoria/3/75 (H3N2) influenza neuraminidase mutants as potential broad-spectrum subunit vaccines against influenza A.

Wim MartinetTom DerooXavier SaelensEls BeirnaertPeter VanlandschootRoland ContrerasWalther FiersWilly Min Jou

A1 Journal Article in ARCHIVES OF VIROLOGY

1997

Protection of mice against a lethal influenza challenge by immunization with yeast-derived recombinant influenza neuraminidase.

Wim MartinetXavier SaelensTom DerooSabine NeirynckRoland ContrerasWilly Min JouWalther Fiers

A1 Journal Article in EUROPEAN JOURNAL OF BIOCHEMISTRY

1996

Recombinant neuraminidase vaccine protects against lethal influenza.

Tom DerooWilly Min JouWalther Fiers

A1 Journal Article in VACCINE

1994

Recombinant influenza virus neuraminidase : secretie, zuivering en immunologische karakterisering

Tom DerooWalther Fiers

1993

A new method for purification of influenza neuraminidase released by pronase digestion.

Tom DerooWilly Min JouWalther Fiers