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Researcher
Tom Delanghe
Profile
Projects
Publications
Activities
Awards & Distinctions
10
Results
2023
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
Yves Dondelinger
Dario Priem
Jon Huyghe
Tom Delanghe
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
CELL DEATH & DISEASE
2023
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
Hannelore Van Eeckhoutte
Chantal Donovan
Richard Y. Kim
Thomas M. Conlon
Meshal Ansari
Haroon Khan
Ranjith Jayaraman
Nicole G. Hansbro
Yves Dondelinger
Tom Delanghe
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2023
2022
The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach
Pauline Puylaert
Isabelle Coornaert
Cedric H. G. Neutel
Yves Dondelinger
Tom Delanghe
Mathieu Bertrand
Pieter-Jan Guns
Guido R. Y. De Meyer
Wim Martinet
A1
Journal Article
in
BIOMEDICINES
2022
2021
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor
Tom Delanghe
Jon Huyghe
Seungheon Lee
Dario Priem
Samya Van Coillie
Barbara Gilbert
Sze Men Choi
Peter Vandenabeele
Alexei Degterev
Gregory D. Cuny
et al.
A1
Journal Article
in
CELL DEATH & DISEASE
2021
Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell death and inflammation
Tom Delanghe
Mathieu Bertrand
Yves Dondelinger
Dissertation
2021
2020
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation
Lucie Laurien
Masahiro Nagata
Hannah Schünke
Tom Delanghe
Janica L. Wiederstein
Snehlata Kumari
Robin Schwarzer
Teresa Corona
Marcus Krüger
Mathieu Bertrand
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2020
RIPK1 kinase-dependent death : a symphony of phosphorylation events
Tom Delanghe
Yves Dondelinger
Mathieu Bertrand
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2020
2019
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
Yves Dondelinger
Tom Delanghe
Dario Priem
Meghan A Wynosky-Dolfi
Daniel Sorobetea
Diego Rojas Rivera
Piero Giansanti
Ria Roelandt
Julia Gropengiesser
Klaus Ruckdeschel
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
2018
MK2 puts an additional brake on RIPK1 cytotoxic potential
Yves Dondelinger
Tom Delanghe
Mathieu Bertrand
Editorial material
2018
2017
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
Yves Dondelinger
Tom Delanghe
Diego Rojas Rivera
Dario Priem
Tinneke Delvaeye
Inge Bruggeman
Franky Van Herreweghe
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
NATURE CELL BIOLOGY
2017