Research Explorer

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Researcher

Timothy Douglas

Awards & Distinctions

70 Results

2020

Enhancement of biomimetic enzymatic mineralization of gellan gum polysaccharide hydrogels by plant-derived gallotannins

Timothy DouglasJulia K. KepplerMarta VandrovcováMartin PlencnerJana BeranováMichelle FeuereisenBogdan ParakhonskiyYulia SvenskayaVsevolod AtkinAnna Ivanova et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2019

Pectin-bioactive glass self-gelling, injectable composites with high antibacterial activity

Timothy DouglasMichal DziadekJosefien SchietseMatthieu BooneHeidi DeclercqTom CoenyeValérie VanhoorneChris VervaetLieve BalcaenMaria Buchweitz et al.

A1 Journal Article in CARBOHYDRATE POLYMERS

Phenolic plant extract enrichment of enzymatically mineralized hydrogels

Timothy DouglasMarco Lopez-HerediaAleksandra PulczynskaAgata ŁapaKrzysztof PietrygaDavid SchaubroeckSonia SantosAdriana PaisGilles BrackmanKarel De Schamphelaere et al.

A2 Journal Article in ENGINEERING OF BIOMATERIALS = INŻYNIERIA BIOMATERIAŁÓW

2018

ANN prediction of corrosion behaviour of uncoated and biopolymers coated cp-Titanium substrates

Suman KumariHanuma Reddy TiyyaguraTimothy DouglasElbeshary Aldesouki Ahmed MohammedMieke AdriaensRegina Fuchs-GodecMK .MohanAndre Skirtach

A1 Journal Article in MATERIALS & DESIGN

Application of whey protein isolate in bone regeneration : effects on growth and osteogenic differentiation of bone-forming cells

Timothy DouglasMarta VandrovcováNikola KročilováJulia K KepplerJana ZárubováAndre SkirtachLucie Lucie Bačáková

A1 Journal Article in JOURNAL OF DAIRY SCIENCE

Mineralization of gellan gum hydrogels with calcium and magnesium carbonates by alternate soaking in solutions of calcium/magnesium and carbonate ion solutions

Marco A Lopez-HerediaAgata ŁapaKatarzyna ReczynskaKrzysztof PietrygaLieve BalcaenAna C MendesDavid SchaubroeckPascal Van Der VoortAgnieszka DukopilAgnieszka Plis et al.

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

Novel injectable gellan gum hydrogel composites incorporating Zn- and Sr-enriched bioactive glass microparticles : high-resolution X-ray microcomputed tomography, antibacterial and in vitro testing

Timothy DouglasMichal DziadekSvetlana GorodzhaJana LiskovaGilles BrackmanValérie VanhoorneChris VervaetLieve BalcaenMaria del Rosario Florez GarciaAldo R Boccaccini et al.

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

Novel self-gelling injectable hydrogel/alpha-tricalcium phosphate composites for bone regeneration : physiochemical and microcomputer tomographical characterization

Timothy DouglasJosefien SchietseAneta ZimaSvetlana GorodzhaBogdan ParakhonskiyDmitry KhalenkowRoman ShkarinAnna IvanovaTilo BaumbachVenera Weinhardt et al.

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Phytase-mediated enzymatic mineralization of chitosan-enriched hydrogels

Jana LiškováTimothy DouglasWijnants WijnantsSangram Keshari SamalAna C MendesIoannis ChronakisLucie BacákováAndre Skirtach

A1 Journal Article in MATERIALS LETTERS

Ulvan-chitosan polyelectrolyte complexes as matrices for enzyme induced biomimetic mineralization

Mamoni DashSangram Keshari SamalAndrea MorelliCristina BartoliHeidi DeclercqTimothy DouglasPeter DubruelFederica Chiellini

A1 Journal Article in CARBOHYDRATE POLYMERS

Whey protein complexes with green tea polyphenols : antimicrobial, osteoblast-stimulatory, and antioxidant activities

Matthew CarsonJulia K KepplerGilles BrackmanDaniel DawoodMarta VandrovcovaKarim Fawzy El-SayedTom CoenyeKarin SchwarzSusan A ClarkeAndre Skirtach et al.

A1 Journal Article in CELLS TISSUES ORGANS

2017

Bioinspired, biomimetic, double-enzymatic mineralization of hydrogels for bone regeneration with calcium carbonate

Marco A Lopez-HerediaAgata ŁapaAna C MendesLieve BalcaenSangram Keshari SamalFeng ChaiPascal Van Der VoortChristian StevensBogdan ParakhonskiyIoannis S Chronakis et al.

A1 Journal Article in MATERIALS LETTERS

Ca:Mg:Zn:CO3 and Ca:Mg:CO3 - tri- and bi-elemental carbonate microparticles for novel injectable self-gelling hydrogel-microparticle composites for tissue regeneration

Timothy DouglasKatarzyna SobczykAgata ŁapaKatarzyna WlodarczykGilles BrackmanIrina VidiashevaKatarzyna ReczyńskaKrzysztof PietrygaDavid SchaubroeckVitaliy Bliznuk et al.

A1 Journal Article in BIOMEDICAL MATERIALS

Composites of gellan gum hydrogel enzymatically mineralized with calcium–zinc phosphate for bone regeneration with antibacterial activity

Timothy DouglasMagdalena PilarzMarco Lopez-HerediaGilles BrackmanDavid SchaubroeckLieve BalcaenVitaliy BliznukPeter DubruelChristine Knabe-DucheyneFrank Vanhaecke et al.

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

Enzymatic, urease-mediated mineralization of gellan gum hydrogel with calcium carbonate, magnesium-enriched calcium carbonate and magnesium carbonate for bone regeneration applications

Timothy DouglasAgata ŁapaSangram Keshari SamalHeidi DeclercqDavid SchaubroeckAna C MendesPascal Van Der VoortAgnieszka DokupilAgnieszka PlisKarel De Schamphelaere et al.

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

Enzymatically biomineralized chitosan scaffolds for tissue-engineering applications

Mamoni DashSangram Keshari SamalTimothy DouglasDavid SchaubroeckSander C LeeuwenburghPascal Van Der VoortHeidi DeclercqPeter Dubruel

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

Titanium surface functionalization with coatings of chitosan and polyphenol-rich plant extracts

Timothy DouglasSuman KumariKinga DziadekMichal DziadekAnatoly AbalymovPieter CoolsGilles BrackmanTom CoenyeRino MorentMK. Mohan et al.

A1 Journal Article in MATERIALS LETTERS

2016

Enrichment of enzymatically mineralized gellan gum hydrogels with phlorotannin-rich Ecklonia cava extract Seanol® to endow antibacterial properties and promote mineralization

Timothy DouglasAgnieszka DokupilKatarzyna ReczyńskaGilles BrackmanMalgorzata Krok-BorkowiczJulia K KepplerMojca BožičPascal Van Der VoortKrzysztof PietrygaSangram Keshari Samal et al.

A1 Journal Article in BIOMEDICAL MATERIALS

Enzymatic, urease-mediated mineralization of gellan gum hydrogel with calcium carbonate, magnesium-enriched calcium carbonate and magnesium carbonate for bone regeneration applications

Timothy DouglasAgata LapaSangram Keshari SamalHeidi DeclercqDavid SchaubroeckAna C MendesPascal Van Der VoortAgnieszka DokupilAgnieszka PlisKarel De Schamphelaere et al.

Generation of composites for bone tissue-engineering applications consisting of gellan gum hydrogels mineralized with calcium and magnesium phosphate phases by enzymatic means

Timothy DouglasGrzegorz KrawcyzkElzbieta PamulaHeidi DeclercqDavid SchaubroeckMiroslaw M BuckoLieve BalcaenPascal Van Der VoortVitaliy BliznukNatasja Van den Vreken et al.

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

High-resolution synchrotron X-ray analysis of bioglass-enriched hydrogels

Svetlana GorodzhaTimothy DouglasSangram Keshari SamalRainer DetschKatarzyna Cholewa-KowalskaKevin BraeckmansAldo R BoccacciniAndre SkirtachVerena WeinhardtTilo Baumbach et al.

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Injectable self-gelling composites for bone tissue engineering based on gellan gum hydrogel enriched with different bioactive glasses

Timothy DouglasWojciech PiwowarczyckJana LiskovaDavid SchaubroeckSander C LeeuwenburghGilles BrackmanLieve BalcaenRainer DetschHeidi DeclercqKatarzyna Cholewa-Kowalska et al.

Novel injectable, self-gelling hydrogel-microparticle composites for bone regeneration consisting of gellan gum and calcium and magnesium carbonate microparticles

Timothy DouglasAgata ŁapaKatarzyna ReczyńskaMałgorzata Krok-BorkowiczKrzysztof PietrygaSangram Keshari SamalHeidi DeclercqDavid SchaubroeckMarijn BoonePascal Van Der Voort et al.

A1 Journal Article in BIOMEDICAL MATERIALS

Novel self-gelling, injectable composites for bone regeneration based on gellan gum hydrogel and calcium and magnesium carbonate microparticles

Timothy DouglasAgatha LapaKatarzyna ReczynskaMalgorzata Krok-BorkowiczKrzysztof PietrygaSangram Keshari SamalDavid SchaubroeckMarijn BoonePascal Van Der VoortKarel De Schamphelaere et al.

Vaterite coatings on electrospun polymeric fibers for biomedical applications

Mariia SavelevaAnatoly A AbalymovGerman P LyubunIrina V VidyashevaAlexey M YashchenokTimothy DouglasDmitry A GorinBogdan Parakhonskiy

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

2015

Accelerated, double-enzymatic mineralization of hydrogels for bone regeneration

Timothy DouglasAgata ŁapaElżbieta PamulaAndre Skirtach

Biofunctionalization of poly(L-lactide-co-glycolide) by post-plasma grafting of 2-aminoethyl methacrylate and gelatin immobilization

Malgorzata Krok-BorkowiczOlga MusialPaulina KruczalaPiotr DobrzynskiTimothy DouglasSandra Van VlierberghePeter DubruelElzbieta Pamula

A1 Journal Article in MATERIALS LETTERS

Biomimetic chitosan-calcium carbonate composite scaffolds for applications in bone regeneration

Timothy DouglasSangram Keshari SamalDavid SchaubroeckKevin BraeckmansAndre Skirtach

Biomimetic mineralization of hydrogels

Timothy Douglas

Bookchapter in Biomineralization and biomaterials : fundamentals and applications

CaCO3, MgCO3 and (Mg/Ca)CO3 microparticles for applications in bone regeneration : synthesis, characterization and incorporation in self-gelling hydrogel-microparticle composites

Katarzyna ReczyńskaTimothy DouglasKrzysztof PietrygaAgata ŁapaAndre SkirtachElżbieta Pamuła

Chitosan hydrogels enriched with polyphenols: antibacterial activity, cell adhesion and growth and mineralization

Jana LiškováTimothy DouglasJana BeranováAgata SkwarcyńskaMojca BožičSangram Keshari SamalZofia ModrzejewskaSelestina GorgievaVanja KokolLucie Bačáková

A1 Journal Article in CARBOHYDRATE POLYMERS

Collagen-lactoferrin fibrillar coatings enhance osteoblast proliferation and differentiation

Marta VandrovcovaTimothy DouglasSascha HeinemannDieter ScharnweberPeter DubruelLucie Bacakova

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Development of thermosensitive hydrogels of chitosan, sodium and magnesium glycerophosphate for bone regeneration applications

Jana LiskováLucie BačakováAgata L SkwarczyńskaOlga MusialVitaliy BliznukKarel De SchamphelaereZofia ModrzejewskaTimothy Douglas

A2 Journal Article in JOURNAL OF FUNCTIONAL BIOMATERIALS

Enhancement of autologous blood-derived hydrogel biomaterial platelet-rich fibrin (PRF) by loading with osteoblast-like cells

Timothy DouglasNicolai PurczVolker Gassling

Enhancement of mineralized hydrogels for bone regeneration with polyphenol-rich seaweed-derived dietary supplement Seanol®: effects on mineralization, antioxidant properties and cytocompatibility

Timothy DouglasKatarzyna ReczyńskaMalgorzata Krok-BorkowiczKrzysztof PietrygaMojca BožičElżbieta PamulaAndre Skirtach

Enzymatic mineralization of electospun chitosan fiber membranes with calcium carbonate for bone regeneration applications

Timothy DouglasAna C MendesBoštjan CibejDavid SchaubroeckChristian StevensIoannis S ChronakisAndre Skirtach

Injectable self-gelling composite scaffolds based on gellan gum hydrogel and ion-loaded zeolites

Timothy DouglasAgata L SkwarczynskaJolanta WarcholBart LucasKevin BraeckmansAndre Skirtach

Pulsed laser deposition of magnesium-doped calcium phosphate coatings on porous polycaprolactone scaffolds produced by rapid prototyping

Marta VandrovcovaTimothy DouglasWaldemar MrózOlga MusialDavid SchaubroeckBoguslaw BudnerRenata SyrokaPeter DubruelLucie Bacakova

A1 Journal Article in MATERIALS LETTERS

Self healing materials for bone regeneration

Timothy DouglasSander Leeuwenburgh

Bookchapter in Self-healing materials : pioneering research in the Netherlands

Structure of chitosan gels mineralized by sorption

Zofia ModrzejewskaAgata SkwarczyńskaTimothy DouglasDorota BiniaśWaldemar ManiukiewiczJan Sielski

A1 Journal Article in JOURNAL OF MOLECULAR STRUCTURE

2014

Additive manufacturing of cell-loaded alginate enriched with alkaline phosphatase for bone tissue engineering application

Rainer DetschBapi SarkerTobias ZehnderAldo R BoccacciniTimothy Douglas

A2 Journal Article in BIONANOMATERIALS

Alginate-hydroxypropyl cellulose hydrogel microbeads for alkaline phosphatase encapsulation

Anna KarewiczKatarzyna ZasadaDorota BielskaTimothy DouglasJohn JansenSander LeeuwenburghMaria Nowakowska

A1 Journal Article in JOURNAL OF MICROENCAPSULATION

Apatite enrichment of hydrogel biomaterials for bone regeneration

Timothy Douglas

Bookchapter in Apatite : synthesis, structural characterization and biomedical applications

Composites of polyvinyl alcohol (PVA) hydrogel and calcium and magnesium phosphate formed by enzymatic functionalization

Timothy DouglasAgnieszka PiegatHeidi DeclercqDavid SchaubroeckLieve BalcaenVitaliy BliznukBernhard De MeyerFrank VanhaeckeMaria CornelissenMiroslawa El Fray et al.

A1 Journal Article in MATERIALS LETTERS

Enrichment of chitosan hydrogels with perfluorodecalin promotes gelation and stem cell vitality

Timothy DouglasMaciej PilarekIlona KalaszczyńskaIlona SenderekAgata SkwarczyńskaVincent CuijpersZosia ModrzejewskaMałgorzata Lewandowska-SzumielPeter Dubruel

A1 Journal Article in MATERIALS LETTERS

Enzymatic mineralization of gellan gum hydrogel for bone tissue-engineering applications and its enhancement by polydopamine

Timothy DouglasMalgorzata WlodarczykElzbieta PamulaHeidi DeclercqEric LW de MulderMiroslaw M BuckoLieve BalcaenFrank VanhaeckeMaria CornelissenPeter Dubruel et al.

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

Injectable self-gelling composites for bone tissue engineering based on gellan gum hydrogel enriched with different bioglasses

Timothy DouglasWojciech PiwowarczykElzbieta PamulaJana LiskovaDavid SchaubroeckSander CG LeeuwenburghGilles BrackmanLieve BalcaenRainer DetschHeidi Declercq et al.

A1 Journal Article in BIOMEDICAL MATERIALS

Polylactide nanofibers with hydroxyapatite as growth substrates for osteoblast-like cells

Katarina NovotnaMartina ZajdlovaTomas SuchyDaniel HadrabaFrantisek LopotMargit ZaloudkovaTimothy DouglasMarcela MunzarovaMartina JuklickovaDenisa Stranska et al.

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Structural characteristics of thermosensitive chitosan glutamate hydrogels in variety of physiological environments

Zofia ModrzejewskaKatarzyna NawrotekWaldemar ManiukiewiczTimothy Douglas

A1 Journal Article in JOURNAL OF MOLECULAR STRUCTURE

Wspomaganie wzrostu komórek kostnych na hydrożelach z gumy gellan za pomocą mineralizacji enzymatycznej

Krzysztof PietrygaJoana CostaPedro PereiraTimothy DouglasElżbieta Pamuła

A2 Journal Article in ENGINEERING OF BIOMATERIALS = INŻYNIERIA BIOMATERIAŁÓW

2013

Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatese

Timothy DouglasAgata SkwarczynskaZofia ModrzejewskaLieve BalcaenDavid SchaubroeckSylvia LyckeFrank VanhaeckePeter VandenabeelePeter DubruelJohn A Jansen et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Biomimetic mineralization of hydrogel biomaterials for bone tissue engineering

Timothy DouglasElzbieta PamulaSander CG Leeuwenburgh

Bookchapter in Biomimetics : advancing nanobiomaterials and tissue engineering

Composites of polyvinyl alcohol (PVA) hydrogel and calcium and magnesium phosphate formed by enzymatic functionalization for bone regeneration

Timothy DouglasAgnieszka PiegatDavid SchaubroeckVitaliy BliznukBernhard De MeyerLieve BalcaenHeidi DeclercqFrank VanhaeckeMiroslawa El FrayPeter Dubruel

Evaluation of enzyme and cell-loaded alginate matrices for bioplotting to improve bone regeneration ability

Timothy DouglasTobias ZehnderBapi SarkarAldo BoccacciniPeter DubruelRainer Detsch

Magnesium-enhanced enzymatically mineralized platelet-rich fibrin for bone regeneration applications

Volker GasslingTimothy DouglasNicolai PurczDavid SchaubroeckLieve BalcaenVitaliy BliznukHeidi DeclercqFrank VanhaeckePeter Dubruel

A1 Journal Article in BIOMEDICAL MATERIALS

Structural characteristics of thermosensitive chitosan glutaminate hydrogels

Zofia ModrzejewskaKatarzyna NawrotekRoman ZarzyckiTimothy Douglas

A2 Journal Article in PROGRESS ON CHEMISTRY AND APPLICATION OF CHITIN AND ITS DERIVATIVES

2012

Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatase

Timothy DouglasAgata SkwarczynskaZofia ModrzejewskaLieve BalcaenDavid SchaubroeckSylvia LyckeFrank VanhaeckePeter VandenabeelePeter DubruelJohn Jansen et al.

Artificial extracellular matrices of collagen fibrils and lactoferrin as coatings to enhance osteoblast behavior

Marta VandrovcovaLucie BacakovaPeter DubruelTimothy Douglas

Chitosan thermosensitive hydrogels for bone regeneration

Zofia ModrzejewskaAgata SkwarczynskaTimothy Douglas

Composites of polyvinyl alcohol (PVA) hydrogel and calcium and magnesium phosphate formed by enzymatic functionalization

Timothy DouglasAgnieszka PiegatDavid SchaubroeckBernhard De MeyerMiroslawa El FrayPeter Dubruel

Enzymatic mineralization of bioglass/gellan gum composites

Magdalena PilarzWojciech PiwowarczykGrzegorz KrawczykKatarzyna Cholewa-KowalskaTimothy DouglasElzbieta Pamula

Enzymatic mineralization of gellan gum hydrogels with calcium and magnesium phosphate for bone tissue engineering

Timothy DouglasGrzegorz KrawczykElzbieta PamulaHeidi DeclercqDavid SchaubroeckMiroslaw BuckoLieve BalcaenPascal Van Der VoortFrank VanhaeckeMaria Cornelissen et al.

Enzymatic mineralization of hydrogels for bone tissue engineering by incorporation of alkaline phosphatase

Timothy DouglasPhilip B MessersmithSafak ChasanAntonius G MikosEric LW de MulderGlenn DicksonDavid SchaubroeckLieve BalcaenFrank VanhaeckePeter Dubruel et al.

A1 Journal Article in MACROMOLECULAR BIOSCIENCE

Enzymatic mineralization of hydrogels with calcium and magnesium phosphate

Timothy DouglasGrzegorz KrawczykElzbieta PamulaHeidi DeclercqDavid SchaubroeckMiroslaw BuckoLieve BalcaenPascal Van Der VoortFrank VanhaeckeMaria Cornelissen et al.

Enzymatically induced mineralization of platelet-rich fibrin

Timothy DouglasVolker GasslingHeidi DeclercqNicolai PurczElzbieta PamulaHåvard HaugenSafak ChasanEric de MulderJohn A JansenSander CG Leeuwenburgh

A1 Journal Article in JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Glycosaminoglycans metabolism

Manuela ViolaTimothy DouglasLaura AlanizBarbara Bartolini

Editorial material

In vivo application of foam titanium implants with magnesium-doped octacalcium phosphate and hydroxyapatite thin films deposited by PLD method

Waldemar MrozB BudnerR ZalecznyA ProkopiukK NiedzielskiAnna SlosarczykTimothy DouglasDieter Schwarze

Insight into gelation mechanism of chitosan/polyol salt theromgelling system

Katarzyna NawrotekZofia ModrzejewskaRoman ZarzyckiTimothy DouglasPeter Dubruel

Nanofibrous poly(lactide-co-glycolide) membranes loaded with diamond nanoparticles as promising substrates for bone tissue engineering

Martin ParizekTimothy DouglasKatarina NovotnaAlexander KromkaMariea BradyAndrea RenzingEske VossMarketka JarosovaLukas PalatinusPavel Tesarek et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF NANOMEDICINE

2010

Acceleration of gelation and mineralization of chitosan hydrogels by alkaline phosphatase

Timothy DouglasAgata SkwarczynskaZofia ModrzejewskaLieve BalcaenDavid SchaubroeckSylvia LyckeFrank VanhaeckePeter VandenabeelePeter DubruelJohn A Jansen et al.