Research Explorer

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Researcher

Tim Van Langenhove

27 Results

2023

Exome sequencing and multigene panel testing in 1,411 patients with adult-onset neurologic disorders

Nika SchuermansHannah VerdinJody GhijselsMadeleine HellemansElke DebackereElke BogaertSofie SymoensLeslie NaesensElien LecomteDavid Crosiers et al.

A1 Journal Article in NEUROLOGY-GENETICS

2022

HEARDEM : the importance of evaluating hearing in people with dementia

Katrien KestensMarijke MiattonTim Van LangenhoveHannah Keppler

Therapy-induced electrophysiological changes in primary progressive aphasia : a preliminary study

Jara StalpaertSofie StandaertLien D’HelftMarijke MiattonAnne SiebenTim Van LangenhoveWouter DuyckPieter van MierloMiet De Letter

A1 Journal Article in FRONTIERS IN HUMAN NEUROSCIENCE

2021

A case series of verbal semantic processing in primary progressive aphasia : evidence from the N400 effect

Jara StalpaertElissa-Marie CocquytMarijke MiattonAnne SiebenTim Van LangenhovePieter van MierloMiet De Letter

A1 Journal Article in INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS

GAD65 autoimmune encephalitis : a cause of rapidly evolving frontotemporal atrophy

Alexander VanhoorneTim Van LangenhoveMarijke MiattonGuy Laureys

A1 Journal Article in ALZHEIMER DISEASE & ASSOCIATED DISORDERS

In-depth phenotypic description of TBK1 mutations ; a frequent cause of FTD and ALS in the Flanders-Belgian population

H GossyeS Van MosseveldeJ Van der ZeeY VermeirenN De RoeckJan De BleeckerP CrasP De DeynS EngelborghsTim Van Langenhove et al.

The electrophysiological correlates of phoneme perception in primary progressive aphasia : a preliminary case series

Jara StalpaertMarijke MiattonAnne SiebenTim Van LangenhovePieter van MierloMiet De Letter

A1 Journal Article in FRONTIERS IN HUMAN NEUROSCIENCE

2020

A genetic answer to a neuropsychiatric challenge

Hannah DhaeneCéline CousaertHannelore TandtTim Van LangenhoveMarijke MiattonHelena GosseyeGilbert LemmensAnne Sieben

A2 Journal Article in ACTA PSYCHIATRICA BELGICA

Language and speech markers of primary progressive aphasia : a systematic review

Jara StalpaertElissa-Marie CocquytYana CrielLieselot SegersMarijke MiattonTim Van LangenhovePieter van MierloMiet De Letter

A1 Journal Article in AMERICAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY

2019

Clinical and electrophysiological markers of primary progressive aphasia : a systematic review

Jara StalpaertElissa-Marie CocquytLieselot SegersTim Van LangenhoveMarijke MiattonPieter van MierloMiet De Letter

Klinisch logopedische en elektrofysiologische markers van primair progressieve afasie : een systematische review

Jara StalpaertElissa-Marie CocquytLieselot SegersTim Van LangenhoveMarijke MiattonPieter van MierloMiet De Letter

2018

Clinical variability and onset age modifiers in an extended Belgian GRN founder family

Eline WautersSara Van MosseveldeKristel SleegersJulie van der ZeeSebastiaan EngelborghsAnne SiebenRik VandenbergheStephanie PhiltjensMarleen Van den BroeckKarin Peeters et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

2017

Clinical evidence of disease anticipation in families segregating a C9orf72 repeat expansion

Sara Van MosseveldeJulie van der ZeeIlse GijselinckKristel SleegersJan De BleeckerAnne SiebenRik VandenbergheTim Van LangenhoveJonathan BaetsOlivier Deryck et al.

A1 Journal Article in JAMA NEUROLOGY

2016

Clinical features of TBKI carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

Sara Van MosseveldeJulie van der ZeeIlse GijselinckSebastiaan EngelborghsAnne SiebenTim Van LangenhoveJan De BleeckerJonathan BaetsMathieu VandenbulckeKoen Van Laere et al.

A1 Journal Article in BRAIN

The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter

I GijselinckS Van MosseveldeJ van der ZeeAnne SiebenS EngelborghsJan De BleeckerA IvanoiuO DeryckD EdbauerM Zhang et al.

A1 Journal Article in MOLECULAR PSYCHIATRY

2015

Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains

Jonathan JanssensStephanie PhiltjensGernot KleinbergerSara Van MosseveldeJulie van der ZeeRita CacaceSebastiaan EngelborghsAnne SiebenJulia Banzhaf-StrathmannLubina Dillen et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

2014

Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia

Elise CuyversKarolien BettensStéphanie PhiltjensTim Van LangenhoveIlse GijselinckJulie van der ZeeSebastiaan EngelborghsMathieu VandenbulckeJasper Van DongenNathalie Geerts et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Julie van der ZeeTim Van LangenhoveGabor G KovacsLubina DillenWilliam DeschampsSebastiaan EngelborghsRadoslav MatějMathieu VandenbulckeAnne SiebenBart Dermaut et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA

2013

A pan-European study of the C9orf72 repeat associated with FTLD : geographic prevalence, genomic instability, and intermediate repeats

Julie van der ZeeIlse GijselinckLubina DillenTim Van LangenhoveJessie TheunsSebastiaan EngelborghsStéphanie PhiltjensMathieu VandenbulckeKristel SleegersAnne Sieben et al.

A1 Journal Article in HUMAN MUTATION

Distinct clinical characteristics of C9orf72 expansion carriers compared with GRN, MAPT, and nonmutation carriers in a Flanders-Belgian FTLD cohort

Tim Van LangenhoveJulie van der ZeeIlse GijselinckSebastiaan EngelborghsRik VandenbergheMathieu VandenbulckeJan De BleeckerAnne SiebenJan VersijptAdrian Ivanoiu et al.

A1 Journal Article in JAMA NEUROLOGY

Explorative genetic study of UBQLN2 and PFN1 in an extended Flanders-Belgian cohort of frontotemporal lobar degeneration patients

Lubina DillenTim Van LangenhoveSebastiaan EngelborghsMathieu VandenbulckeStayko SarafovIvailo TournevCeline MerlinPatrick CrasRik VandenberghePeter P De Deyn et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

2012

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum : a gene identification study

Ilse GijselinckTim Van LangenhoveJulie van der ZeeKristel SleegersStephanie PhiltjensGernot KleinbergerJonathan JanssensKarolien BettensCaroline Van CauwenbergheSandra Pereson et al.

A1 Journal Article in LANCET NEUROLOGY

Ataxin-2 polyQ expansions in FTLD-ALS spectrum disorders in Flanders-Belgian cohorts

Tim Van LangenhoveJulie van der ZeeSebastiaan EngelborghsRik VandenberghePatrick SantensMarleen Van den BroeckMaria MattheijssensKarin PeetersDirk NuyttenPatrick Cras et al.

A1 Journal Article in NEUROBIOLOGY OF AGING

Distinct clinical characteristics of C9orf72 expansion carriers compared to GRN, MAPT and non-mutation carries in a Flanders-Belgian FTLD cohort

Tim Van LangenhoveJulie van der ZeeIlse GijselinckSebastiaan EngelborghsRik VandenbergheMathieu VandenbulckeJan De BleeckerAnne SiebenAdrian IvanoiuOliver Deryck et al.

Identification of novel causal genes for frontotemporal lobar degeneration using whole genome sequencing

Stephanie PhiltjensIlse GijselinckTim Van LangenhoveJulie van der ZeeSebastiaan EngelborgsRik VandenbergheMatthieu VandenbulckePatrick SantensPeter De DeynChristine Van Broeckhoven et al.

The genetics and neuropathology of frontotemporal lobar degeneration

Anne SiebenTim Van LangenhoveSebastiaan EngelborghsJean-Jacques MartinPaul BoonPatrick CrasPeter-Paul De DeynPatrick SantensChristine Van BroeckhovenMarc Cruts

A1 Journal Article in ACTA NEUROPATHOLOGICA

2011

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

Julie van der ZeeTim Van LangenhoveGernot KleinbergerKristel SleegersSebastiaan EngelborghsRik VandenberghePatrick SantensMarleen Van Den BroeckGeert JorisJolien Brys et al.

A1 Journal Article in BRAIN