Research Explorer

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Researcher

Tim Van de Walle

Awards & Distinctions

10 Results

2021

Recent contributions of quinolines to antimalarial and anticancer drug discovery research

Tim Van de WalleLore CoolsSven MangelinckxMatthias D'hooghe

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2020

Design and synthesis of novel ferrocene-quinoline conjugates and evaluation of their electrochemical and antiplasmodium properties

Aleksandra MinićTim Van de WalleKristof Van HeckeJill CombrinckPeter J. SmithKelly ChibaleMatthias D'hooghe

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Development of antimalarial quinoline-based conjugates and anticancer nitroxoline derivatives

Tim Van de WalleMatthias D'hoogheSven Mangelinckx

Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents

Tim Van de WalleMaya BooneJulie Van PuyveldeJill CombrinckPeter J. SmithKelly ChibaleSven MangelinckxMatthias D'hooghe

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel nitroxoline analogs with potent cathepsin B exopeptidase inhibitory activity

Tim Van de WalleMarina BriandAna MitrovićIzidor SosičStanislav GobecJanko KosLeentje PersoonsDirk DaelemansSteven De JongheZorica Ubiparip et al.

A1 Journal Article in CHEMMEDCHEM

2019

Synthesis and cytotoxic evaluation of monocarbonyl curcuminoids and their pyrazoline derivatives

Tim Van de WalleAtiruj TheppawongCharlotte GrootaertSteven De JongheLeentje PersoonsDirk DaelemansKristof Van HeckeJohn Van CampMatthias D'hooghe

A1 Journal Article in MONATSHEFTE FUR CHEMIE

Synthesis of 1,4‐thiazepane‐based curcuminoids with promising anticancer activity

Atiruj TheppawongTim Van de WalleKristof Van HeckeCharlotte GrootaertJohn Van CampMatthias D'hooghe

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of non‐symmetrical nitrogen‐containing curcuminoids in the pursuit of new anticancer candidates

Atiruj TheppawongTim Van de WalleCharlotte GrootaertKristof Van HeckeNathalie CatryTom DesmetJohn Van CampMatthias D'hooghe

A1 Journal Article in CHEMISTRYOPEN

2018

Synthesis of Novel Aza‐aromatic Curcuminoids with Improved Biological Activities towards Various Cancer Cell Lines

Atiruj TheppawongTim Van de WalleCharlotte GrootaertMargot BultinckTom DesmetJohn Van CampMatthias D'hooghe

A1 Journal Article in CHEMISTRYOPEN

2017

Synthesis, biology and structure-activity relationships of novel β-enaminone-, aza-aromatic- and thiazepane-based curcuminoids

Atiruj TheppawongTim Van de WalleCharlotte GrootaertJohn Van CampMatthias D'hooghe