Research Explorer

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Researcher

Tim Lammens

128 Results

2021

CircRNAs dysregulated in juvenile myelomonocytic leukemia : CircMCTP1 stands out

Anna Dal MolinMattias HofmansEnrico GaffoAlessia BuratinHélène CavéChristian FlothoValerie de HaasCharlotte M. NiemeyerJan StaryPieter Van VlierbergheJan PhilippéBarbara De MoerlooseGeertruij te KronnieSilvia BresolinTim LammensStefania Bortoluzzi

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring

Araceli Diez-FraileJoke De CeulaerCharlotte DerpoorterChristophe SpaasTom De BackerPhilippe LamoralJohan AbeloosTim Lammens

A1 Journal Article in CELLS

Current developments and hurdles in CAR-T cell therapy for acute myeloid leukaemia

Laurens Van CampTim LammensAnne UyttebroeckBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeEva TerrasBarbara DenysLaurence DedekenMarie-Francoise DresseJutte Van der Werff Ten BoschMattias HofmansJan PhilippéTim Lammens

A1 Journal Article in PEDIATRIC RESEARCH

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Judith M. BoerMaria Grazia ValsecchiFemke M. HormannŽeljko AntićMarketa ZaliovaClaire SchwabGiovanni CazzanigaChloé ArfeuilleHélène CavéAndishe AttarbaschiSabine StrehlGabriele EscherichToshihiko ImamuraKentaro OhkiTanja A. GrüberRosemary SuttonAgata PastorczakTim LammensFrédéric LambertChi Kong LiEnrique Carrillo de Santa PauSteve HoffmannAnja MörickeChristine J. HarrisonMonique L. Den BoerPaola De LorenzoRonald W. StamAnke K. BergmannRob Pieters

A1 Journal Article in LEUKEMIA

Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies

Melanie DeckerTim LammensAlina FersterMiriam ErlacherAyami YoshimiCharlotte M. NiemeyerMartijn P. T. ErnstMarc H. G. P. RaaijmakersNicolas DuployezAndreas FlaumDoris SteinemannBrigitte SchlegelbergerThomas IlligTim Ripperger

A1 Journal Article in LEUKEMIA

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensBarbara DepreterYing WuMiriam ErlacherAurélie CayeHélène CavéChristian FlothoValerie de HaasCharlotte M. NiemeyerJan StaryFilip Van NieuwerburghDieter DeforceWouter Van LoockePieter Van VlierbergheJan PhilippéBarbara De Moerloose

A1 Journal Article in SCIENTIFIC REPORTS

Novel therapeutic targets in juvenile myelomonocytic leukaemia : are noncoding RNAs valuable treatment options?

Mattias HofmansTim LammensJan PhilippéBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Novel therapeutic targets in juvenile myelomonocytic leukemia : are noncoding RNAs valuable treatment options?

Mattias HofmansBarbara De MoerlooseJan PhilippéTim Lammens

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

Filip MatthijssensNitesh D. SharmaMonique NysusChristian K. NicklHuining KangDominique R. PerezBeatrice LintermansWouter Van LoockeJuliette RoelsSofie PeirsLisa DemoenTim PietersLindy ReunesTim LammensBarbara De MoerlooseFilip Van NieuwerburghDieter L. DeforceLaurence C. CheungRishi S. KotechaMartijn D. P. RisseeuwSerge Van CalenberghTakeshi TakaradaYukio YonedaFrederik W. van DelftRichard B. LockSeth D. MerkleyAlexandre ChigaevLarry A. SklarCharles G. MullighanMignon L. LohStuart S. WinterStephen P. HungerSteven GoossensEliseo F. CastilloWojciech OrnatowskiPieter Van VlierbergheKsenia Matlawska-Wasowska

U Journal Article in Journal of Clinical Investigation

TARP as antigen in cancer immunotherapy

Jolien VanhoorenCharlotte DerpoorterBarbara DepreterLarissa DenewethJan PhilippéBarbara De MoerlooseTim Lammens

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

2020

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozB SzarzyńskaM LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy ReunesTim PietersFilip MatthijssensWouter Van LoockeB Erarslan-UysalP Richter-PechańskaK DeclerckTim LammensBarbara De MoerlooseDieter DeforceFilip Van NieuwerburghLC CheungRS KotechaMR MansourB GhesquièreG Van CampWV BergheJR KowalczykT SzczepańskiUP DavéAE KulozikSteven GoossensDJ CurtisTom TaghonM DawidowskaS DegermanPieter Van Vlierberghe

A2 Journal Article in BLOOD CANCER DISCOVERY

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Juliette RoelsMorgan ThénozBronislawa SzarzynskaMattias LandforsStien De ConinckLisa DemoenLien ProvezAnna KuchmiySteven StrubbeLindy ReunesTim PietersFilip MatthijssensWouter Van LoockeTim LammensBarbara De MoerlooseMarc R. MansourUtpal DaveSteven GoossensDavid J. CurtisTom TaghonMalgorzata DawidowskaSofie DegermanPieter Van Vlierberghe

Clinical significance of TARP expression in pediatric acute myeloid leukemia

B. DepreterBarbara De MoerlooseKarl VandepoeleA. UyttebroeckA. Van DammeB. DenysL. DedekenM. -F. DresseJ. Van der Werff Ten BoschM. HofmansTessa KerreBart VandekerckhoveJan PhilippéTim Lammens

Clinical significance of TARP expression in pediatric acute myeloid leukemia

Barbara DepreterBarbara De MoerlooseKarl VandepoeleAnne UyttebroeckAn Van DammeBarbara DenysLaurence DedekenMarie-Françoise DresseJutte Van Der Werff Ten BoschMattias HofmansTessa KerreBart VandekerckhoveJan PhilippéTim Lammens

A2 Journal Article in HEMASPHERE

Exploring the molecular and phenotypical heterogeneity between patients with pediatric acute myeloid leukemia

Barbara DepreterTim LammensJan Philippé

In vitro characterization of hippo signaling in hematological childhood malignancies

Charlotte DerpoorterJolien VanhoorenLarissa DenewethKatrien VandemeulebroeckeGenevieve LaureysTim Lammens

Leukaemic stem cells in AML : where are we now? An update on recent findings and detection

Barbara DepreterBarbara De MoerlooseJan PhilippéTim Lammens

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study

Ruben Van PaemelAndries De KokerCharlotte VandeputteLieke van ZogchelTim LammensGenevieve LaureysJo VandesompeleGudrun SchleiermacherMathieu ChicardNadine Van RoyAles VichaG.A.M. TytgatNico CallewaertKatleen De PreterBram De Wilde

U Journal Article in Epigenetics

Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA

Ruben Van PaemelAndries De KokerCharlotte VandeputteLieke Van ZogchelTim LammensGenevieve LaureysJo VandesompeleGudrun SchleiermacherMatthieu ChicardNadine Van RoyAles VichaGodelieve A. M. TytgatNico CallewaertBram De WildeKatleen De Preter

NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia : a good prognostic subtype identified in a collaborative international study

Judith M. BoerMaria Grazia ValsecchiFemke M. HormannZeljko AnticMarketa ZaliovaClaire SchwabGiovanni CazzanigaChloe ArfeuilleHelene CaveAndishe AttarbaschiSabine StrehlGabriele EscherichToshihiko ImamuraKentaro OhkiTanja A. GruberRosemary SuttonAgata PastorczakTim LammensFrederic LambertChi Kong LiEnrique Carrillo de Santa PauSteve HoffmannAnja Moricke

Prospective, real-time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma in Belgium

Veerle MondelaersAlina FersterAnne UyttebroeckBenedicte BrichardJuttevan der Werff ten BoschKoenraad NorgaNadine FrancotteCaroline PietteKatrien VandemeulebroeckeCharlotte VerbekeSusanne SchmidtYves BenoitTim LammensBarbara De Moerloose

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Retrospective analysis of the incidence and characteristics of paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia in Belgium

Lindsey De SmaeleMattias HofmansTim LammensA Van DammeJutte van der Werff ten BoschA FersterJoris VerlooyC ChantrainJan PhilippéNadine Van RoyP De PaepeV LabarqueBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

Barbara DepreterKarin WeeningKarl VandepoeleMagnus EssandBarbara De MoerlooseMaria ThemeliJacqueline CloosDiana HanekampIne MoorsInge D'hontBarbara DenysAnne UyttebroeckAn Van DammeLaurence DedekenSYLVIA SNAUWAERTGlenn GoetgelukStijn De MunterTessa KerreBart VandekerckhoveTim LammensJan Philippé

A1 Journal Article in HAEMATOLOGICA

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtJulie MorscioLindy ReunesJuliette RoelsValentina BardelliBéatrice LintermansWouter Van LoockeAfonso AlmeidaLaurence C. CheungRishi S. KotechaMarc R. MansourAnne UyttebroeckPeter VandenbergheRoberta La StarzaCristina MecucciTim LammensNadine Van RoyBarbara De MoerlooseJoao T. BarataTom TaghonSteven GoossensPieter Van Vlierberghe

A1 Journal Article in BLOOD

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Catherine L. CarmichaelJueqiong WangThao NguyenOluseyi KolawoleAissa BenyoucefCharlotte De MazièreAnna MilneSona SamuelKevin Robert GillinderSoroor Hediyeh-zadehAnh Ngoc Quynh VoYizhou HuangKathy KnezevicWilliam R. L. McInnesBenjamin J. ShieldsHelen MitchellMatthew E. RitchieTim LammensBéatrice LintermansPieter Van VlierbergheNicholas WongKatharina HaighJulie A. I. ThomsEmma ToulminDavid J. CurtisEthan P. OxleyRoss A. DickinsDominik BeckAndrew C PerkinsMatthew P. McCormackMelissa J. DavisGeert BerxJohannes ZuberJohn E. PimandaBenjamin T. KileSteven GoossensJody J. Haigh

A1 Journal Article in BLOOD

The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing

L ZubovicS PiazzaT TebaldiL CozzutoG PalazzoV SidarovichV De SanctisR BertorelliTim LammensMattias HofmansBarbara De MoerlooseJ PonomarenkoM PigazziR MasettiC MecucciG BassoP Macchi

A1 Journal Article in JOURNAL OF HEMATOLOGY & ONCOLOGY

The interplay of parent and child coping responses in understanding child functioning in the context of living with a parent with or without chronic pain

Elke Van LierdeLiesbet GoubertTim LammensLamia Ben BrahimEva Van den BusscheTine Vervoort

A1 Journal Article in CLINICAL JOURNAL OF PAIN

The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children : a review

Ruben Van PaemelROSALIE VLUGKatleen De PreterNadine Van RoyFranki SpelemanLeen WillemsTim LammensGenevieve LaureysGudrun SchleiermacherGodelieve AM TytgatKathy AstrahantseffHedwig DeubzerBram De Wilde

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

2019

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte van der Werff ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De MoerlooseJan PhilippéTim Lammens

Deciphering molecular heterogeneity in pediatric AML using a cancer vs normal transcriptomic approach

Barbara DepreterMattias HofmansEva TerrasAnne UyttebroeckAn Van DammeAlina FersterJutte Van der Werff Ten BoschMarie-Françoise DresseKarl VandepoeleBarbara De MoerlooseJan PhilippéTim Lammens

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria MilaniFilip MatthijssensWouter Van LoockeKaat DurinckJuliette RoelsSofie PeirsMorgan ThénozTim PietersLindy ReunesBéatrice LintermansNiels VandammeTim LammensNadine Van RoyFilip Van NieuwerburghDieter DeforceClaire SchwabSusana RaimondiLuciano Dalla PozzaAndrew J CarrollBarbara De MoerlooseYves BenoitSteven GoossensGeert BerxChristine J HarrisonGiuseppe BassoHélène CavéRosemary SuttonVahid AsnafiJules MeijerinkCharles MullighanMignon LohPieter Van Vlierberghe

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia : proof of concept study

Mattias HofmansBarbara DepreterTim LammensHelene CaveChristian FlothoHenrik HasleValerie de HaasCharlotte M. NiemeyerJan StaryPieter Van VlierbergheJan PhilippéBarbara De Moerloose

Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study

Ruben Van PaemelAndries De KokerCharlotte VandeputteLieke van ZogchelTim LammensGenevieve LaureysJo VandesompeleGudrun SchleiermacherMathieu ChicardNadine Van RoyAles VichaGodelieve A. M. TytgatNico CallewaertKatleen De PreterBram De Wilde

Non-invasive classification of pediatric tumor types using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study

Ruben Van PaemelA. De KokerCharlotte VandeputteL. M. J. van ZogchelM. ChicardTim LammensJo VandesompeleNadine Van RoyG. SchleiermacherG. A. M. TytgatA. VichaN. CallewaertKatleen De PreterBram De Wilde

Noonan syndrome-associated myeloproliferative disorder with somatically acquired monosomy 7 : impact on clinical decision making

Mattias HofmansRieke SchroederTim LammensChristian FlothoCharlotte NiemeyerNadine Van RoyWim DecaluweJan PhilippéBarbara De Moerloose

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

Tim PietersSara T'SasLisa DemoenAndré Pedro Pinto De AlmeidaLieven HaenebalckeFilip MatthijssensKelly LemeireJinke D'HontFrédérique VanrockeghemTino HochepiedBéatrice LintermansLindy ReunesTim LammensGeert BerxJody J. HaighSteven GoossensPieter Van Vlierberghe

A1 Journal Article in SCIENTIFIC REPORTS

Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing

Charlotte DerpoorterKarl VandepoeleAraceli Diez FraileKatrien VandemeulebroeckeBram De WildeFranki SpelemanNadine Van RoyTim LammensGenevieve Laureys

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01

Barbara De MoerlooseArdine ReedijkGeertruida H. de BockTim LammensValerie de HaasBarbara DenysLaurence DedekenMarry M. van den Heuvel-EibrinkMaroeska te LooAnne UyttebroeckAn Van DammeJutte Van der Werff-ten BoschJozsef ZsirosGertjan KaspersEveline de Bont

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van Der LindenJilke De WildeBjörn MentenLieke van ZogchelG.A.M. TytgatBram De WildeFranki SpelemanKatleen De PreterNadine Van RoyTim Lammens

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van Der LindenJilke De WildeBjörn MentenL. van ZogchelL. TytgatBram De WildeFranki SpelemanKatleen De PreterTim LammensNadine Van Roy

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van Der LindenJilke De WildeBjörn MentenLieke van ZogchelGAM TytgatBram De WildeFranki SpelemanKatleen De PreterNadine Van RoyTim Lammens

Successful copy number alteration profiling using circulating cell-free tumor DNA as a non-invasive alternative for tissue biopsies in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van Der LindenJilke De WildeBjörn MentenLieke van ZogchelG.A.M. TytgatBram De WildeFranki SpelemanKatleen De PreterNadine Van RoyTim Lammens

TARP as immunotherapeutic target in AML expressed in the LSC compartment

Barbara DepreterKarin WeeningKarl VandepoeleM EssandBarbara De MoerlooseM ThemeliJ CloosD HanekampIne MoorsInge D'hontBarbara DenysA UyttebroeckA Van DammeL DedekenSYLVIA SNAUWAERTGlenn GoetgelukStijn De MunterTessa KerreBart VandekerckhoveTim LammensJan Philippé

2018

A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T- and B-cell acute lymphoblastic leukemias in vivo

Hien Anh NguyenYing SuJenny Yu ZhangAleksandar AntanasijevicMichael CaffreyAmanda M SchalkLi LiuDamiano RondelliAnnie OhDolores L MahmudMaarten C BoslandAndre Kajdacsy-BallaSofie PeirsTim LammensVeerle MondelaersBarbara De MoerlooseSteven GoossensMichael J SchlichtKasim K KabirovAlexander V LyubimovBradley J MerrillYogen SaunthararajahPieter Van VlierbergheArnon Lavie

A1 Journal Article in CANCER RESEARCH

Cancer-related mRNA expression analysis using a novel flow cytometry-based assay

Barbara DepreterJan PhilippéMAGALI MEULBarbara DenysKarl VandepoeleBarbara De MoerlooseTim Lammens

A1 Journal Article in CYTOMETRY PART B-CLINICAL CYTOMETRY

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

Fjoralba ZekaAnneleen DecockAlan Van GoethemKatrien VanderheydenFleur DemuynckTim LammensHetty HelsmoortelJoëlle VermeulenRosa NogueraAna P. BerbegallValérie CombaretGudrun SchleiermacherGenevieve LaureysAlexander SchrammJohannes H. SchulteSven RahmannJulie Bienertová-VaškůPavel MazánekMarta JeisonShifra AshMichael D. HogartyMirthala Moreno-SmithEveline BarbieriJason ShohetFrank BertholdTom Van MaerkenFranki SpelemanMatthias FischerKatleen De PreterPieter MestdaghJo Vandesompele

A1 Journal Article in JCI INSIGHT

Circulating microRNA biomarkers for metastatic neuroblastoma

Fjoralba ZekaAlan Van GoethemTim LammensAnneleen DecockHetty HelsmoortelGenevieve LaureysMichael HogartyEveline BarbieriJason ShohetFrank BertholdFranki SpelemanMatthias FischerTom Van MaerkenKatleen De PreterPieter MestdaghJo Vandesompele

Current understanding and future research priorities in malignancy associated with inborn errors of immunity and DNA repair disorders : the perspective of an interdisciplinary working group

Simon BomkenJutte van der Werff Ten BoschAndishe AttarbaschiChris M. BaconArndt BorkhardtKaan BoztugUte FischerFabian HauckRoland P. KuiperTim LammensJan LoeffenBénédicte NevenQiang Pan-HammarströmIsabella QuintiMarkus G. SeidelKlaus WarnatzClaudia WehrArjan C. LankesterAndrew R. Gennery

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis

Maria V CorriasStefano ParodiAndrei TchirkovTim LammensAles VichaClaudia PasqualiniCatarina TrägerYania YáñezSandro DallorsoLuigi VaresioRoberto LukschGenevieve LaureysDominique Valteau-CouanetAdela CaneteUlrike PöetschgerRuth LadensteinSusan A Burchill

A1 Journal Article in PEDIATRIC BLOOD & CANCER

Exploring the long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensS BresolinH CavéC FlothoH HasleHetty HelsmoortelM Van den Heuvel-EibrinkC NiemeyerJ StaryNadine Van RoyPieter Van VlierbergheJan PhilippéBarbara De Moerloose

Genes at the crossroad of primary immunodeficiencies and cancer

Charlotte DerpoorterMaria Bordon Cueto De BraemGenevieve LaureysFilomeen HaerynckTim Lammens

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Leukaemic stem cell load at diagnosis predicts the development of relapse in young acute myeloid leukaemia patients

Diana HanekampBarbara DenysGertjan JL KaspersJeroen G te MarveldeGerrit Jan SchuurhuisValerie De HaasBarbara De MoerlooseEveline S de BontC Michel ZwaanAnja de JongBarbara DepreterTim LammensJan PhilippéJacqueline CloosVincent HJ van der Velden

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van PaemelAnneleen DecockCharlotte VandeputteTim LammensGenevieve LaureysFranki SpelemanWim Van CriekingeNadine Van RoyJo VandesompeleKatleen De PreterBram De Wilde

Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van PaemelAnneleen DecockCharlotte VandeputteTim LammensGenevieve LaureysFranki SpelemanWim Van CriekingeNadine Van RoyJo VandesompeleKatleen De PreterBram De Wilde

Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van PaemelAnneleen DecockCharlotte VandeputteTim LammensGenevieve LaureysFranki SpelemanWim Van CriekingeNadine Van RoyJo VandesompeleKatleen De PreterBram De Wilde

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtSofie PeirsJulie MorscioFilip MatthijssensJuliette RoelsLindy ReunesBéatrice LintermansSteven GoossensTim LammensNadine Van RoyAurore TouzartSilvia JenniYi-Chien TsaiFederica LovisaLara MussolinValentina SerafinFilip Van NieuwerburghDieter DeforceAnne UyttebroeckThomas TousseynBirgit BurkhardtWolfram KlapperBarbara De MoerlooseYves BenoitElizabeth MacintyreJean-Pierre BourquinGiuseppe BassoBenedetta AccordiBeat BornhauserJules MeijerinkPeter VandenberghePieter Van Vlierberghe

A1 Journal Article in HAEMATOLOGICA

Predisposing mutations in hippo signaling reveal an actionable target in Burkitt lymphoma

Charlotte DerpoorterKatrien VandemeulebroeckeTieneke BautersJan PhilippéGenevieve LaureysTim Lammens

Recurrently affected genes in juvenile myelomonocytic leukaemia

Julia C ObenauerFrancois G KavelaarsMathijs A SandersAndrica CH de VriesValerie de HaasH Berna BeverlooBarbara De MoerlooseTim LammensMichael DworzakRemco M HoogenboezemPeter JM ValkIvo P TouwMarry M van den Heuvel-Eibrink

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Retrospective study of infant leukaemia in the University Hospitals of Leuven and Ghent

Barbara De MoerlooseE NauwynckK ArtsLeen WillemsV LabarqueTim LammensA Uyttebroeck

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

The genetic basis and cell of origin of mixed phenotype acute leukaemia

Thomas B. AlexanderZhaohui GuIlaria IacobucciKirsten DickersonJohn K. ChoiBeisi XuDebbie Payne-TurnerHiroki YoshiharaMignon L. LohJohn HoranBarbara BuldiniGiuseppe BassoSarah ElitzurValerie de HaasC. Michel ZwaanAllen YeohDirk ReinhardtDaisuke TomizawaNobutaka KiyokawaTim LammensBarbara De MoerlooseDaniel CatchpooleHiroki HoriAnthony MoormanAndrew S. MooreOndrej HrusakSoheil MeshinchiEtan OrgelMeenakshi DevidasMichael BorowitzBrent WoodNyla A. HeeremaAndrew CarrolYung-Li YangMalcolm A. SmithTanja M. DavidsenLeandro C. HermidaPatee GesuwanMarco A. MarraYussanne MaAndrew J. MungallRichard A. MooreSteven J. M. JonesMarcus ValentineLaura J. JankeJeffrey E. RubnitzChing-Hon PuiLiang DingYu LiuJinghui ZhangKim E. NicholsJames R. DowningXueyuan CaoLei ShiStanley PoundsScott NewmanDeqing PeiJaime M. Guidry AuvilDaniela S. GerhardStephen P. HungerHiroto InabaCharles G. Mullighan

A1 Journal Article in NATURE

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensHetty HelsmoortelSilvia BresolinHélène CavéChristian FlothoHenrik HasleMarry M van den Heuvel-EibrinkCharlotte NiemeyerJan StaryNadine Van RoyPieter Van VlierbergheJan PhilippéBarbara De Moerloose

A1 Journal Article in HAEMATOLOGICA

The potential of methylome sequencing in the diagnostic work : up of pediatric solid tumors

Ruben Van PaemelCharlotte VandeputteBram De WildeKatleen De PreterNadine Van RoyJo VandesompeleTim LammensWim Van CriekingeP. UltzNico CallewaertArthur DekokerAnneleen Decock

2017

Digital multiplex ligation-dependent probe amplification for detection of key copy number alterations in T- and B-cell lymphoblastic leukemia

Anne Benard-SlagterIlse ZondervanKarel de GrootFarzaneh GhazaviVirinder SarhadiPieter Van VlierbergheBarbara De MoerlooseClaire SchwabKim VettenrantaChristine J HarrisonSakari KnuutilaJan SchoutenTim LammensSuvi Savola

A1 Journal Article in JOURNAL OF MOLECULAR DIAGNOSTICS

Exome sequencing to identify novel neuroblastoma predisposition genes

Charlotte DerpoorterKarl VandepoeleAraceli Diez FraileKatrien VandemeulebroeckeNadine Van RoyBram De WildeTim LammensGenevieve Laureys

Genetic insights in ETV6/RUNX1-positive B-cell precursor acute lymphoblastic leukaemia

Farzaneh GhazaviTim LammensPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Identification of genetic aberrations predisposing to familial Burkitt lymphoma using whole genome sequencing

Ruben Van PaemelCharlotte DerpoorterRein DemuynckEva TerrasBram De WildeTim LammensGenevieve Laureys

Long non-coding RNAs in leukemia : biology and clinical impact

Tim LammensKaat DurinckAnnelynn WallaertFranki SpelemanPieter Van Vlierberghe

A1 Journal Article in CURRENT OPINION IN HEMATOLOGY

Novel molecular genetic insights in paediatric B-cell precursor acute lymphoblastic leukaemia

Farzaneh GhazaviTim LammensPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients

Nadine Van RoyMalaïka Van Der LindenPauline DepuydtBjörn MentenAnnelies DheedeneCharlotte VandeputteJo Van DorpeGenevieve LaureysMarjolijn RenardTom SanteTim LammensBram De WildeFranki SpelemanKatleen De Preter

Shallow whole genome sequencing on circulating cell-free DNA allows reliable noninvasive copy-number profiling in neuroblastoma patients

Nadine Van RoyMalaïka Van Der LindenBjörn MentenAnnelies DheedeneCharlotte VandeputteJo Van DorpeGenevieve LaureysMarleen RenardTom SanteTim LammensBram De WildeFranki SpelemanKatleen De Preter

A1 Journal Article in CLINICAL CANCER RESEARCH

Unravelling the biology of juvenile myelomonocytic leukaemia using transcriptomics

Hetty HelsmoortelTim LammensPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

2016

A novel multiplex NGS-based digital MLPA assay for copy number detection of 700 target sequences in childhood acute lymphoblastic leukemia

Anne BenardIlse ZondervanJan SchoutenKarel de GrootFarzaneh GhazaviVirinder SarhadiPieter Van VlierbergheBarbara De MoerlooseChristine HarrisonClaire SchwabSakari KnuutilaTim LammensSuvi Savola

Digital MLPA(TM) for copy number detection in childhood acute lymphoblasic leukemia : a novel multiplex NGS-based assay

A BenardBarbara De MoerlooseI ZondervanFarzaneh GhazaviV SarhadiPieter Van VlierbergheTim LammensS KnuutilaS Savola

Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia

Gloria MilaniKaat DurinckFilip MatthijssensSofie PeirsTim PietersLindy ReunesBéatrice LintermansNiels VandammeTim LammensYunlei LiClaire SchwabSusana RaimondiBarbara De MoerlooseYves BenoitGeert BerxChristine HarrisonGiuseppe BassoHelene CaveRosemary SuttonVahid AsnafiCharles MullighanJules MeijerinkMignon LohPieter Van Vlierberghe

Genomic landscape of pediatric mixed phenotype acute leukemia

Thomas B AlexanderZhaohui GuJohn K ChoiMignon LohJohn HoranBarbara BuldiniGiuseppe BassoSarah ElitzurValerie de HaasC Michel ZwaanAllen YeohDirk ReinhardtDaisuke TomizawaTim LammensBarbara De MoerlooseLi ZhouHiroki HoriAnthony MoormanAndrew MooreOndrej HrusakSteve HungerJaime M Guidry AuvilMalcolm A SmithTanja M DavidsenLeandro HermidaPatee GesuwanDaniela S GerhardHiroto InabaCharles G Mullighan

Identification of candidate oncogenes and chromosomal breakpoint sequencing by targeted locus amplification in T-cell acute lymphoblastic leukemia

Eric VroegindeweijTim LammensKirsten Cante-BarrettErik SplinterA UyttebroeckJessica GC Buijs-GladdinesWilco SmitsPeter VandenbergheRenate De SmedtBarbara De MoerlooseMax van MinRob PietersPieter Van VlierbergheJules PP Meijerink

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19

Hetty HelsmoortelBarbara De MoerlooseTim PietersFarzaneh GhazaviSilvia BresolinHelene CaveAndrica de VriesValerie de HaasChristian FlothoVeerle LabarqueCharlotte NiemeyerPascale De PaepeNadine Van RoyJan StaryMarry M van den Heuvel-EibrinkYves BenoitJohannes SchulteSteven GoossensGeert BerxJody J HaighFranki SpelemanPieter Van VlierbergheTim Lammens

A1 Journal Article in HAEMATOLOGICA

LIN28B is overexpressed in pediatric leukemia and regulates LNCRNA H19

Hetty HelsmoortelBarbara De MoerlooseSilvia BresolinHélèe CavéChristian FlothoCharlotte NiemeyerJan StaryMarry van den Heuvel-EibrinkPieter Van VlierbergheTim Lammens

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Hetty HelsmoortelSilvia BresolinTim LammensHélène CavéPeter NoellkeAurélie CayeFarzaneh GhazaviAndrica de VriesHenrik HasleVeerle LabarqueRiccardo MasettiJan StaryMarry M van den Heuvel-EibrinkJan PhilippéNadine Van RoyYves BenoitFranki SpelemanCharlotte NiemeyerChristian FlothoGiuseppe BassoGeertruy te KronniePieter Van VlierbergheBarbara De Moerloose

A1 Journal Article in BLOOD

Leukemia in infants : a retrospective study (1992-2014) in the Ghent University Hospital

Elise NauwynckTim LammensVincent VakaetN Van DammeYves BenoitVeerle MondelaersEls VandecruysGenevieve LaureysL VakaetBarbara De Moerloose

Novel molecular genetic insights in pediatric B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerloosePieter Van VlierbergheTim Lammens

RPPA-Based protein profiling reveals enhanced PI3K/AKT/mTOR signaling in ETV6/RUNX1-positive acute lymphoblastic leukemia patients with low CD200 expression

Farzaneh GhazaviValentina SerafinPieter RondouTim LammensFranki SpelemanBenedetta AccordiBarbara De MoerloosePieter Van Vlierberghe

Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne UyttebroeckFilip Van NieuwerburghDieter DeforceNadine Van RoyFranki SpelemanYves BenoitTim LammensPieter Van Vlierberghe

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertHetty HelsmoortelAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne UyttebroeckFilip Van NieuwerburghDieter DeforceNadine Van RoyFranki SpelemanYves BenoitTim LammensPieter Van Vlierberghe

A1 Journal Article in ONCOTARGET

Unraveling the biology of juvenile myelomonocytic leukemia using transcriptomics

Hetty HelsmoortelBarbara De MoerlooseTim LammensPieter Van Vlierberghe

2015

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Farzaneh GhazaviEmmanuelle ClappierTim LammensStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitOdile MinckesVitor CostaAline FersterFrançoise MazingueGeneviève PlatEmmanuel PlouvierMarilyne PoiréeAnne UyttebroeckJutte Van Der Werff-Ten BoschKarima YakoubenHetty HelsmoortelMAGALI MEULNadine Van RoyJan PhilippéFranki SpelemanHélène CavéPieter Van VlierbergheBarbara De Moerloose

A1 Journal Article in HAEMATOLOGICA

Excellent outcome in pediatric AML with response guided chemotherapy without allogeneic HSCT in first complete remission results from prococol DB-AML01

Eveline de BontArdine ReedijkTim LammensValerie de HaasBarbara DenysLaurence DedekenMarry van den HeuvelMaroeska te LooAnne UyttebroeckAn VandammeJutte VanderWerff-ten BoschJozsef ZsirosGertjan JL KaspersBarbara De Moerloose

MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

Evelien MetsJONI VAN DER MEULENGert Van PeerMichael BoicePieter MestdaghInge Van de WalleTim LammensSteven GoossensBarbara De MoerlooseYves BenoitNadine Van RoyEmmanuelle ClappierBruce PoppeJo VandesompeleHans-Guido WendelTom TaghonPieter RondouJean SoulierPieter Van VlierbergheFranki Speleman

A1 Journal Article in LEUKEMIA

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviTim LammensNadine Van RoyBruce PoppeFranki SpelemanYves BenoitPieter Van VlierbergheBarbara De Moerloose

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

Mutational spectrum of juvenile myelomonocytic leukemia

J ObenauerF KavelaarsACH de VriesM SandersV de HaasBarbara De MoerlooseTim LammensM DworzakC NiemeyerP ValkI TouwMM van den Heuvel-Eibrink

Novel biological insights in T-cell acute lymphoblastic leukemia

Kaat DurinckSteven GoossensSofie PeirsAnnelynn WallaertWouter Van LoockeFilip MatthijssensTim PietersGloria MilaniTim LammensPieter RondouNadine Van RoyBarbara De MoerlooseYves BenoitJody HaighFranki SpelemanBruce PoppePieter Van Vlierberghe

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der MeulenViraj SanghviKonstantinos MavrakisKaat DurinckFang FangFilip MatthijssensPieter RondouMonica RosenTim PietersPeter VandenbergheEric DelabesseTim LammensBarbara De MoerlooseBjörn MentenNadine Van RoyBruno VerhasseltBruce PoppeYves BenoitTom TaghonAri M MelnickFranki SpelemanHans-Guido WendelPieter Van Vlierberghe

A1 Journal Article in BLOOD

The long non-coding RNA H19 is regulated by LIN28B

Hetty HelsmoortelBarbara De MoerlooseTim PietersFarzaneh GhazaviS BresolinH CavéA CayeACH de VriesC FlothoV LabarqueC NiemeyerJan PhilippéJ StarýMM van den Heuvel-EibrinkYves BenoitFranki SpelemanPieter Van VlierbergheTim Lammens

2014

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensSteven GoossensInge Van de WalleKatia RuggeroCharles E de BockSandrine DegryseKirsten Canté-BarrettDelphine BriotEmmanuelle ClappierTim LammensBarbara De MoerlooseYves BenoitBruce PoppeJules P MeijerinkJan CoolsJean SoulierTerence H RabbittsTom TaghonFranki SpelemanPieter Van Vlierberghe

A1 Journal Article in BLOOD

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in early immature T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensSteven GoossensKirsten Canté-BarrettTim LammensBarbara De MoerlooseYves BenoitJean SoulierBruce PoppeTom TaghonJules MeijerinkFranki SpelemanPieter Van Vlierberghe

ABT-199 mediated inhibition of BCL2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensSteven GoossensCharles De BockKirsten Canté-BarrettTim LammensInge Van de WalleBarbara De MoerlooseYves BenoitBruce PoppeTom TaghonJan CoolsJules MeijerinkJean SoulierFranki SpelemanPieter Van Vlierberghe

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

Trudy D BuitenkampShai IzraeliMartin ZimmermannErik ForestierNyla A HeeremaMarry M van den Heuvel-EibrinkRob PietersCarin M KorbijnLewis B SilvermanKjeld SchmiegelowDer-Cheng LiangKeizo HoribeMaurizio AricoAndrea BiondiGiuseppe BassoKarin R RabinMartin SchrappeGunnar CarioGeorg MannMaria MorakRenate Panzer-GrümayerVeerle MondelaersTim LammensHélène CavéBatia StarkIthamar GanmoreAnthony V MoormanAjay VoraStephen P HungerChing-Hon PuiCharles G MullighanAtsushi ManabeGabriele EscherichJerzy R KowalczykJames A WhitlockC Michel Zwaan

A1 Journal Article in BLOOD

Age-associated differential microRNA levels in human follicular fluid reveal pathways potentially determining fertility and success of in vitro fertilization

Araceli Diez FraileTim LammensKelly TillemanWojciech WitkowskiBruno VerhasseltPetra De SutterYves BenoitMarc EspeelKatharina D'Herde

A1 Journal Article in HUMAN FERTILITY

Juvenile myelomonocytic leukaemia: the quest for more specific therapies

Hetty HelsmoortelTim LammensNadine Van RoyJan PhilippéPascale De PaepeYves BenoitFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

LIN28B defines an aggressive subtype of juvenile myelomonocytic leukemia

Hetty HelsmoortelTim LammensFarzaneh GhazaviAurelie CayeHélène CavéChristian FlothoCharlotte NiemeyerJan StarySilvia BresolinRiccardo MasettiAnne UyttebroeckMarry van den Heuvel-EibrinkYves BenoitFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

Mind the gap : translation of genetic research into clinical care in the context of RUNX1-associated leukaemia predisposition

Tim RippergerAlina FersterTim LammensBarbara De MoerlooseLaurence RozenNadira AzziCharlotte M NiemeyerBrigitte SchlegelbergerDoris Steinemann

Prognostic relevance of BTLA/CD200 deletion in pediatric pre-B cell acute lymphoblastic leukemia

Farzaneh GhazaviTim LammensStefan SuciuMarleen BakkusHélène CavéFranki SpelemanYves BenoitBarbara De MoerloosePieter Van Vlierberghe

Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol

Farzaneh GhazaviTim LammensEmmanuelle ClappierStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitYves BertrandOdile MinckesVitor CostaAlina FersterFrançoise MazingueGeneviève PlatEmmanuel PlouvierMarilyne PoiréeAnne UyttebroeckJutte Van Der Werff ten BoschHetty HelsmoortelMAGALI MEULNadine Van RoyJan PhilippéFrank PelemanHélène CavéPieter Van VlierbergheBarbara De Moerloose

The ASH1-RELATED3 SET-domain protein controls cell division competence of the meristem and the quiescent center of the Arabidopsis primary root

Robert KumpfTage ThorstensenMohummad Aminur RahmanJefri HeymanH Zeynep NensethTim LammensUllrich HerrmannRanjan SwarupSilje Veie VeisethGitika EmberlandMalcolm J BennettLieven De VeylderReidunn B Aalen

A1 Journal Article in PLANT PHYSIOLOGY

2013

Delayed elemination of methotrexate by cola beverages in a pediatric acute lymphoblastic leukemia population

Tieneke BautersTim LammensPauline BelinYves BenoitHugo RobaysBarbara De Moerloose

A1 Journal Article in LEUKEMIA & LYMPHOMA

Long non-coding RNAs in pluripotent stem cell biology

Tim LammensINGE D'HONTKatharina D'HerdeYves BenoitAraceli Diez Fraile

A1 Journal Article in VETERINARY QUARTERLY

The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions

Araceli Diez FraileTim LammensYves BenoitKatharina D'Herde

A1 Journal Article in CURRENT MOLECULAR MEDICINE

The need for transparency and good practices in the qPCR literature

Stephen A BustinVladimir BenesJeremy GarsonJan HellemansJim HuggettMikael KubistaReinhold MuellerTania NolanMichael W PfafflGregory ShipleyCarl T WittwerPeter SchjerlingPhilip J DayMónica AbreuBegoña AguadoJean-François BeaulieuAnneleen BeckersSarah BogaertJohn A BrowneFernando Carrasco-RamiroLiesbeth CeelenKate CiborowskiPieter CornillieStephanie CoulonAnn CuypersSara De BrouwerLeentje De CeuninckJurgen De CraeneHélène De NaeyerWard De SpiegelaereKato DeckersAnnelies DheedeneKaat DurinckMargarida Ferreira-TeixeiraAnnelies FieuwJack M GallupSandra Gonzalo-FloresKaren GoossensFemke HeindryckxElizabeth HerringHans HoenickaLaura IcardiRolf JaggiFarzad JavadMichail KarampeliasFrederick KibengeMolly KibengeCandy KumpsIrina LambertzTim LammensAmelia MarkeyPeter MessiaenEvelien MetsSofia MoraisAlberto Mudarra-RubioJustine NakiwalaHilde NelisPal A OlsvikClaudina Perez NovoMichelle PlusquinTony RemansAli RihaniPaulo Rodrigues-SantosPieter RondouRebecca SandersKatharina Schmidt-BleekKerstin SkovgaardKaren SmeetsLaura TaberaStefan ToegelTim Van AckerWim Van Den BroeckJoni Van der MeulenMireille Van GeleGert Van PeerMario Van PouckeNadine Van RoySarah VergultJoris WaumanMarina Tshuikina-WiklanderErik WillemsSara ZaccaraFjoralba ZekaJo Vandesompele

A1 Journal Article in NATURE METHODS

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty HelsmoortelTim LammensPieter MestdaghNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitJo VandesompeleFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty HelsmoortelTim LammensPieter MestdaghNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitJo VandesompeleFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

2012

Improved risk stratification and outcome prediction in children with average risk 1 precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Farzaneh GhazaviTim LammensStefan SuciuGenevieve LaureysMarleen BakkusAlina FersterAnne UyttebroeckPatrick LutzHélène CavéGeneviève PlatNicole DastugueMarie-Françoise DresseJoni Van der MeulenPieter MestdaghJo VandesompeleFranki SpelemanBarbara De MoerlooseYves Benoit

Improved risk-stratification and outcome prediction in children with average risk precursor-B acute lymphoblastic leukemia using a 19-microRNA signature

Farzaneh GhazaviTim LammensStefan SuciuGenevieve LaureysMarleen BakkusAlina FersterAnne UyttebroeckPatrick LutzHélène CavéGeneviève PlatNicole DastugueMarie-Françoise DresseJoni Van der MeulenPieter MestdaghJo VandesompeleFranki SpelemanBarbara De MoerlooseYves Benoit

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization

Mado VandewoestyneCandy KumpsKatrien SwertsBjörn MentenTim LammensJan PhilippéKatleen De PreterGenevieve LaureysNadine Van RoyFranki SpelemanDieter Deforce

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

N-Cadherin in neuroblastoma disease : expression and clinical significance

Tim LammensKatrien SwertsLara DeryckeANNEMIE DE CRAEMERSara De BrouwerKatleen De PreterNadine Van RoyJo VandesompeleFranki SpelemanJan PhilippéYves BenoitKlaus BeiskeMarc BrackeGenevieve Laureys

A1 Journal Article in PLOS ONE

Study of the miRNome of childhood myelodysplastic syndrome

Hetty HelsmoortelTim LammensNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitFranki SpelemanBarbara De Moerloose

2011

Atypical E2F activity coordinates PHR1 photolyase gene transcription with endoreduplication onset

Amandine RadziejwoskiKobe VliegheTim LammensBarbara BerckmansSara MaesMarcel AK JansenClaudia KnappeAndreas AlbertHarald K SeidlitzGünther BahnwegDirk InzéLieven De Veylder

A1 Journal Article in EMBO JOURNAL

Light-dependent regulation of DEL1 is determined by the antagonistic action of E2Fb and E2Fc

Barbara BerckmansTim LammensHilde Van Den DaeleZoltan MagyarLaszlo BögreLieven De Veylder

A1 Journal Article in PLANT PHYSIOLOGY

MicroRNA-based diagnosis, prognosis and treatment of paediatric acute lymphoblastic leukaemia

Tim LammensFarzaneh GhazaviFranki SpelemanYves BenoitBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

2010

Microrna expression in pediatric precursor-B acute lymphoblastic leukemia: biology, classification and prognosis

Tim LammensBarbara De MoerlooseJonas Van BaelenJONI VAN DER MEULENPieter MestdaghBruno VerhasseltJan PhilippéFranki SpelemanYves Benoit

The MCM-Binding Protein ETG1 Aids Sister Chromatid Cohesion Required for Postreplicative Homologous Recombination Repair

Naoki TakahashiMauricio Alberto Quimbaya GomezVeit SchubertTim LammensKlaas VandepoeleIngo SchubertMinami MatsuiDirk InzéGeert BerxLieven De Veylder

A1 Journal Article in PLOS GENETICS

2009

APC/C-CCS52A complexes control meristem maintenance in the Arabidopsis root

Marleen VanstraelenMikhail BalobanOlivier Da InesAntonietta CultroneTim LammensVéronique BoudolfSpencer BrownLieven De VeylderPeter MergaertEva Kondorosi

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptotic, necrotic and autophagic cell death types in pathophysiological conditions: morphological and histological aspects

Araceli Diez FraileTim LammensKatharina D'Herde

Bookchapter in Phagocytosis of dying cells : from molecular mechanisms to human disease

Atypical E2Fs: new players in the E2F transcription factor family

Tim LammensJing LiGustavo LeoneLieven De Veylder

A1 Journal Article in Trends in Cell Biology

CDKB1;1 forms a functional complex with CYCA2;3 to suppress endocycle onset

Véronique BoudolfTim LammensJoanna BorucJelle Van LeeneHilde Van Den DaeleSara MaesGert Van IsterdaelEugenia RussinovaEva KondorosiErwin WittersGeert De JaegerDirk InzéLieven De Veylder

A1 Journal Article in Plant Physiology

Quantitative RNA expression analysis with Affymetrix Tiling 1.0R arrays identifies new E2F target genes

Naïra NaouarKlaas VandepoeleTim LammensTineke CasneufGeorg ZellerPaul Van HummelenDetlef WeigelGunnar RätschDirk InzéMartin KuiperLieven De VeylderMarnik Vuylsteke

A1 Journal Article in Plant Journal

2008

Atypical E2F activity restrains APC/C-CCS52A2 function obligatory for endocycle onset

Tim LammensVéronique BoudolfLeila Kheibarshekan AslL Panagiotis ZalmasTarik GaamoucheSara MaesMarleen VanstraelenEva KondorosiNicholas B La ThangueWilly GovaertsDirk InzéLieven De Veylder

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DNA replication checkpoint aids survival of plants deficient in the novel replisome factor ETG1

Naoki TakahashiTim LammensVéronique BoudolfSara MaesTakeshi YoshizumiGeert De JaegerErwin WittersDirk InzéLieven De Veylder

A1 Journal Article in EMBO JOURNAL