Research Explorer

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Researcher

Tim De Meyer

Publications & Research Data

Awards & Distinctions

164 Results

2025

Comprehensive analysis of the melanoma DNA methylome identifies LY75 methylation as an independent marker predicting poor clinical outcome

Karin van den HurkKim LommenLouis CoussementDanique van den KerkhofMara BeckersGeert TrooskensLeander Van NesteMarloes OosterhofRemco van DoornJoost J. van den Oord et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Concurrent invasions of European starlings in Australia and North America reveal population-specific differentiation in shared genomic regions

Natalie R. HofmeisterKatarina C. StuartWesley C. WarrenScott J. WernerMelissa BatesonGregory F. BallKatherine L. BuchananDavid W. BurtAdam P. A. CardiliniPhillip Cassey et al.

A1 Journal Article in MOLECULAR ECOLOGY

Dissecting the genetic basis of gene regulation and host plant adaptation in a generalist pest

Femke De GraeveTim De MeyerThomas Van Leeuwen

Independent genetic mapping experiments identify diverse molecular determinants of host adaptation in a generalist herbivore

Ernesto Villacis PerezFemke De GraeveBerdien De BeerSeham Ali AlshamiRick De JongTim De MeyerThomas Van Leeuwen

A1 Journal Article in MOLECULAR ECOLOGY

maelstRom : the modeller of allele-specific transcriptomics

Cedric StroobandtTim De MeyerFrank Peelman

Population-level allelic dispersion modeling by maelstRom yields genome-wide maps of allele-specific dysregulation during early carcinogenesis

Cedric StroobandtLouis CoussementTine GoovaertsFemke De GraeveJeroen GalleWim Van CriekingeTim De Meyer

A1 Journal Article in GIGASCIENCE

The molecular causes and clinical consequences of dysregulation at the HM13 locus in cancer

Floris VoorthuijzenTim De MeyerWim Van Criekinge

2024

Changes in histone lysine acetylation, but not DNA methylation during facultative hibernation in Syrian hamster liver

Marloes OosterhofLouis CoussementAlienke van PijkerenMarcel KwiatkowskiMartijn R. H. ZwindermanFrank J. DekkerTim De MeyerVera A. ReitsemaRainer BischoffVictor Guryev et al.

A2 Journal Article in EPIGENETICS COMMUNICATIONS

Characterization of loss-of-imprinting in breast cancer at the cellular level by integrating single-cell full-length transcriptome with bulk RNA-seq data

Muhammad Talal AminLouis CoussementTim De Meyer

A1 Journal Article in BIOMOLECULES

Intergenerational acquired resistance against root-knot nematodes in rice : role of DCL3a in spring loading of jasmonate and ethylene responses

Aniko MeijerM. R. AtighiKristof DemeestereTim De MeyerKlaas VandepoeleTina Kyndt

Loss-of-imprinting of HM13 leads to poor prognosis in clear cell renal cell carcinoma

Floris VoorthuijzenCedric StroobandtWim Van CriekingeTine GoovaertsTim De Meyer

A1 Journal Article in BIOMOLECULES

Multimodal deregulation of imprinted gene HM13 : a pan-cancer study

Floris VoorthuijzenCedric StroobandtJeroen GalleLouis CoussementJim ClauwaertTine GoovaertsRyan EnglanderOlga AnczukowGerben MenschaertWim Van Criekinge et al.

Overexpression of the ribosome-inactivating protein OsRIP1 modulates the jasmonate signaling pathway in rice

Simin ChenNoémie De ZutterAniko MeijerKoen GistelinckPieter WytynckIsabel VerbekeVinicius Jose Da Silva OsterneSubramanyam KondetiTim De MeyerKris Audenaert et al.

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Proteome-wide genetic investigation of large artery stiffness

Marie-Joe DibJoe David AzzoLei ZhaoOday SalmanSushrima GanMarc De BuyzereTim De MeyerChristina EbertKushan GunawardhanaLaura Liu et al.

A1 Journal Article in JACC-BASIC TO TRANSLATIONAL SCIENCE

Quantitative transcriptomic and epigenomic data analysis : a primer

Louis CoussementWim Van CriekingeTim De Meyer

A2 Journal Article in BIOINFORMATICS ADVANCES

The phenylalanine ammonia-lyase inhibitor AIP induces rice defence against the root-knot nematode Meloidogyne graminicola

Jing LiuHannes LefevereLouis CoussementIlse DelaereTim De MeyerKristof DemeestereMonica HöfteJonathan GershenzonChhana UllahGodelieve Gheysen

A1 Journal Article in MOLECULAR PLANT PATHOLOGY

2023

A bioinformatics-driven exploration of the evolutionary (dis)advantages of epigenetics

Louis CoussementTim De MeyerWim Van Criekinge

Dicer-like 3a mediates intergenerational resistance against root-knot nematodes in rice via hormone responses

Aniko MeijerMohammad Atighi Quchan AtighKristof DemeestereTim De MeyerKlaas VandepoeleTina Kyndt

A1 Journal Article in PLANT PHYSIOLOGY

Diproline-induced resistance to parasitic nematodes in the same and subsequent rice generations : roles of iron, nitric oxide and ethylene

Jonas De KeselEli BonneureMichael FreiTim De MeyerSven MangelinckxTina Kyndt

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Liver transcriptomic and methylomic analyses identify transcriptional mitogen-activated protein kinase regulation in facultative hibernation of Syrian hamster

Louis CoussementMarloes M. OosterhofVictor GuryevVera A. ReitsemaJojanneke J. BruintjesMaaike GorisHjalmar R. BoumaTim De MeyerMarianne G. RotsRobert H. Henning

A1 Journal Article in PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Multimodal deregulation of imprinted gene HM13 leads to pan-cancer upregulation of putative oncogene MCTS2

Floris VoorthuijzenTine GoovaertsCedric StroobandtJeroen GalleRyan EnglanderOlga AnczukowWim Van CriekingeGerben MenschaertTim De Meyer

Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers

Musa IdrisLouis CoussementMaria M. M. AlvesTim De MeyerVeerle Melotte

A1 Journal Article in EPIGENETICS & CHROMATIN

2022

Copy number gain and loss-of-imprinting lead to HM13 intron retention across multiple cancer types

Floris VoorthuijzenTine GoovaertsCedric StroobandtJeroen GalleWim Van CriekingeTim De Meyer

Dehydroascorbate induces plant resistance in rice against root‐knot nematode Meloidogyne graminicola

Satish ChavanJonas De KeselWillem DesmedtEva DegrooteRichard Raj SinghGiang Thanh Nguyen ThiKristof DemeestereTim De MeyerTina Kyndt

A1 Journal Article in MOLECULAR PLANT PATHOLOGY

Spatiotemporal expression profile of novel and known small RNAs throughout rice plant development focussing on seed tissues

Aniko MeijerTim De MeyerKlaas VandepoeleTina Kyndt

A1 Journal Article in BMC GENOMICS

Trans-driven variation in expression is common among detoxification genes in the extreme generalist herbivore Tetranychus urticae

Andre KurlovsBerdien De BeerMeiyuan JiMarilou VandenholeTim De MeyerRené FeyereisenRichard M. ClarkThomas Van Leeuwen

A1 Journal Article in PLOS GENETICS

Transcript- and annotation-guided genome assembly of the European starling

Katarina C. StuartRichard J. EdwardsYuanyuan ChengWesley C. WarrenDavid W. BurtWilliam B. SherwinNatalie R. HofmeisterScott J. WernerGregory F. BallMelissa Bateson et al.

A1 Journal Article in MOLECULAR ECOLOGY RESOURCES

2021

A hypomorphic mutant of PHD domain protein male meiocytes death 1

Bing LiuChunlian JinNico De StormeSébastien SchotteCédric SchindfesselTim De MeyerDanny Geelen

A1 Journal Article in GENES

Chitin in strawberry cultivation : foliar growth and defense response promotion, but reduced fruit yield and disease resistance by nutrient imbalances

Caroline De TenderBart VandecasteeleBruno VerstraetenSarah OmmeslagTim De MeyerJill De VisscherPeter DawyndtLieven ClementTina KyndtJane Debode

A1 Journal Article in MOLECULAR PLANT-MICROBE INTERACTIONS

Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma

Kevin RothLouis CoussementElena V. KnatkoMaureen HigginsSandra SteyaertCharlotte M. ProbyTim De MeyerAlbena T. Dinkova-Kostova

A1 Journal Article in EBIOMEDICINE

DNA methylation regulates transcription factor-specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon

Jolien DiddensLouis CoussementCarolina Frankl-VilchesGaurav MajumdarSandra SteyaertSita M. Ter HaarJeroen GalleEllen De MeesterSarah De KeulenaerWim Van Criekinge et al.

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Genome-wide shifts in histone modifications at early stage of rice infection with Meloidogyne graminicola

Mohammad Atighi Quchan AtighBruno VerstraetenTim De MeyerTina Kyndt

A1 Journal Article in MOLECULAR PLANT PATHOLOGY

Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC

Glenn RademakersMaartje MassenAlexander KochMuriel X. DrahtNikkie BuekersKim A. D. WoutersNathalie VaesTim De MeyerBeatriz CarvalhoGerrit A. Meijer et al.

A1 Journal Article in CLINICAL EPIGENETICS

Insights into the interactions between rice and root-knot nematodes from an epigenetic perspective

Bruno VerstraetenTina KyndtTim De Meyer

Non-coding RNAs in the interaction between rice and Meloidogyne graminicola

Bruno VerstraetenMohammad Atighi Quchan AtighVirginia Ruiz-FerrerCarolina EscobarTim De MeyerTina Kyndt

A1 Journal Article in BMC GENOMICS

The genome of the extremophile Artemia provides insight into strategies to cope with extreme environments

Stephanie De VosStephane RombautsLouis CoussementWannes DermauwMarnik VuylstekePatrick SorgeloosJames S. CleggZiro NambuFilip Van NieuwerburghParisa Norouzitallab et al.

A1 Journal Article in BMC GENOMICS

The RNA Atlas expands the catalog of human non-coding RNAs

Lucia LorenziHua-Sheng ChiuFrancisco Avila CobosStephen GrossPieter-Jan VoldersRobrecht CannoodtJustine NuytensKatrien VanderheydenJasper AnckaertSteve Lefever et al.

A1 Journal Article in NATURE BIOTECHNOLOGY

The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)

Lucia LorenziHua-Sheng ChiuFrancisco Avila CobosStephen GrossPieter-Jan VoldersRobrecht CannoodtJustine NuytensKatrien VanderheydenJasper AnckaertSteve Lefever et al.

2020

Chorismate mutase and isochorismatase, two potential effectors of the migratory nematode Hirschmanniella oryzae, increase host susceptibility by manipulating secondary metabolite content of rice

Lander BautersTina KyndtTim De MeyerKris MorreelWout BoerjanHannes LefevereGodelieve Gheysen

A1 Journal Article in MOLECULAR PLANT PATHOLOGY

Exploring allele-specific expression mechanisms in health and disease

Tine GoovaertsTim De MeyerWim Van Criekinge

Genome‐wide DNA hypomethylation shapes nematode pattern‐triggered immunity in plants

Mohammad Atighi Quchan AtighBruno VerstraetenTim De MeyerTina Kyndt

A1 Journal Article in NEW PHYTOLOGIST

Molecular correlates of hypothalamic development in songbird ontogeny in comparison with the telencephalon

Gaurav MajumdarGarima YadavJulie HamaideLouis CoussementTim De MeyerMarleen VerhoyeWim Vanden BergheAnnemie Van der LindenJacques Balthazart

A1 Journal Article in FASEB JOURNAL

Molecular insights into the compatible and incompatible interactions between sugar beet and the beet cyst nematode

Razieh GhaemiEbrahim PourjamNaser SafaieBruno VerstraetenSeyed Bagher MahmoudiRahim MehrabiTim De MeyerTina Kyndt

A1 Journal Article in BMC PLANT BIOLOGY

Muscle strength is a major determinant of the blood pressure response to isometric stress testing : the Asklepios population study

Caroline Van daeleJulio Chirinos MedinaTim De MeyerMarc De BuyzereMichel LangloisSofie BekaertPatrick SegersThierry GillebertErnst Rietzschel

A1 Journal Article in JOURNAL OF HYPERTENSION

Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals

Sam KintWim TrypsteenWard De SpiegelaereEva MalatinkováSabine Kinloch-de LoesTim De MeyerWim Van CriekingeLinos Vandekerckhove

A1 Journal Article in CLINICAL EPIGENETICS

2019

DNA hypomethylation confers enhanced immunity against parasitic nematodes in rice

Mohammad Atighi Quchan AtighBruno VerstraetenTim De MeyerTina Kyndt

High SNP diversity in the non-toxic indigenous Jatropha curcas germplasm widens the potential of this upcoming major biofuel crop species

Katrien VandepitteAndreia Valdés-RodríquezOdilon Sánchez-SánchezHanne De KortJorge Martinez-HerreraEliseo García-PérezTim De MeyerArturo Pérez-VázquezBart MuysOlivier Honnay

A1 Journal Article in ANNALS OF BOTANY

MEXPRESS update 2019

Alexander KochJana JeschkeWim Van CriekingeManon van EngelandTim De Meyer

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Selection of miRNA reference genes for plant defence studies in rice (Oryza sativa)

Bruno VerstraetenLien De SmetTina KyndtTim De Meyer

A1 Journal Article in PLANTA

Targeted RNA-seq successfully identifies normal and pathogenic splicing events in breast/ovarian cancer susceptibility and Lynch syndrome genes

Rita D BrandãoKlaas MensaertIrene López-PerolioDemis TserpelisMarkos XenakisVanessa LattimoreLogan C WalkerAnders KvistAna VegaSara Gutiérrez-Enríquez et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

The RNA Atlas, a single nucleotide resolution map of the human transcriptome

Lucia LorenziHua-Sheng ChiuFrancisco Avila CobosStephen GrossPieter-Jan VoldersRobrecht CannoodtJustine NuytensKatrien VanderheydenJasper AnckaertSteve Lefever et al.

The role of epigenetics in the interaction between rice and parasitic nematodes

Tina KyndtMohammad Atighi Quchan AtighBruno VerstraetenAniko MeijerTim De Meyer

The role of ncRNAs in the interaction between root-knot nematode and rice

Bruno VerstraetenMohammad Atighi Quchan AtighTim De MeyerTina Kyndt

2018

A comprehensive overview of genomic imprinting in breast and its deregulation in cancer

Tine GoovaertsSandra SteyaertChari VandenbusscheJeroen GalleOlivier ThasWim Van CriekingeTim De Meyer

A1 Journal Article in NATURE COMMUNICATIONS

Analysis of DNA methylation in cancer : location revisited

Alexander KochSophie C JoostenZheng FengTim C de RuijterMuriel X DrahtVeerle MelotteKim M SmitsJurgen VeeckJames G HermanLeander Van Neste et al.

A1 Journal Article in NATURE REVIEWS CLINICAL ONCOLOGY

Body mass index is negatively associated with telomere length : a collaborative cross-sectional meta-analysis of 87 observational studies

Marij GielenGeja J HagemanEvangelia E AntoniouKatarina NordfjallMassimo ManginoMuthuswamy BalasubramanyamTim De MeyerAudrey E HendricksErik J GiltaySteven C Hunt et al.

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL NUTRITION

Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure

Louis CoussementSelin BolcaWim Van CriekingeGeert TrooskensKlaas MensaertKatrien PoelsNathalie RochePhillip BlondeelLode GodderisHerman Depypere et al.

A1 Journal Article in SCIENTIFIC REPORTS

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Alexander TeumerLayal ChakerStefan GroenewegYong LiCelia Di MunnoCaterina BarbieriUlla T SchultheissMichela TragliaTarunveer S AhluwaliaMasato Akiyama et al.

A1 Journal Article in NATURE COMMUNICATIONS

Letter by De Meyer regarding article, 'Short leukocyte telomere length precedes clinical expression of atherosclerosis: the blood-and-muscle model'

A1 Journal Article in CIRCULATION RESEARCH

Leukocyte telomere length and diet in the apparently healthy, middle-aged Asklepios population

Tim De MeyerSofie BekaertMarc De BuyzereDirk De BacquerMichel LangloisNitin ShivappaJames R HébertThierry GillebertErnst RietzschelInge Huybrechts

A1 Journal Article in SCIENTIFIC REPORTS

Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces

Christopher J NicholsonKuldeep SinghRobert J SaphirsteinYuan Z GaoQian LiJoanna G ChiuPaul LeavisGermaine C VerwoertGF MitchellTyrone Porter et al.

A1 Journal Article in JOURNAL OF THE AMERICAN HEART ASSOCIATION

Telomere length as cardiovascular aging biomarker

Tim De MeyerTim NawrotSofie BekaertMarc De BuyzereErnst RietzschelVicente Andrés

A1 Journal Article in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

2017

A four-gene promoter methylation marker panel consisting of GREM1, NEURL, LAD1, and NEFH predicts survival of clear cell renal cell cancer patients

Iris JH van VlodropSophie C JoostenTim De MeyerKim M SmitsLeander Van NesteVeerle MelotteMarcella MLL BaldewijnsLeo J SchoutenPiet A van den BrandtJana Jeschke et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

Below-ground attack by the root knot nematode Meloidogyne graminicola predisposes rice to blast disease

Tina KyndtHenok Zemene YimerAshley HaeckRichard Raj SinghDavid De VleesschauwerSimon DenilTim De MeyerMonica HöfteKristof DemeestereGodelieve Gheysen

A1 Journal Article in MOLECULAR PLANT-MICROBE INTERACTIONS

Below-ground attack by the root knot nematode Meloidogyne graminicola predisposes rice to blast disease

Tina KyndtHenok Zemene YimerAshley HaeckRichard Raj SinghDavid De VleesschauwerSimon DenilTim De MeyerMonica HöfteKristof DemeestereGodelieve Gheysen

Characterization of the methylome of a preclinical model of cutaneous squamous cell carcinoma identifies intronic hypermethylation of Filip1l, a novel tumour suppressor gene and Wnt signalling inhibitor

Kevin RothElena V KnatkoMaureen HigginsTim De MeyerAlbena T Dinkova-Kostova

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer

Linda JW BoschGeert TrooskensPetur SnaebjornssonVeerle MH CoupéSandra MongeraJosien C HaanSusan D RichmanMiriam KoopmanJolien TolTim De Meyer et al.

A1 Journal Article in ONCOTARGET

Epigenetic profiling in cancer

Geert TrooskensWim Van CriekingeTim De Meyer

Epigenetic sampling effects : nephrectomy modifies the clear cell renal cell cancer methylome

Christophe Van NesteAlexander LairdFiach O’MahonyWim Van CriekingeDieter DeforceFilip Van NieuwerburghThomas PowlesDavid J HarrisonGrant D StewartTim De Meyer

A1 Journal Article in CELLULAR ONCOLOGY

Epigenetica : heeft onze levensstijl impact op de gezondheid van onze kleinkinderen

Jana AsselmanTim De MeyerTina Kyndt

Article in a magazine

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer

Tushar TomarNicolette G AlkemaLeroy SchreuderGert Jan MeersmaTim De MeyerWim Van CriekingeHarry G KlipHeidi FieglEls van NieuwenhuysenIgnace Vergote et al.

A1 Journal Article in BMC MEDICINE

Microbial community dynamics and response to plant growth-promoting microorganisms in the rhizosphere of four common food crops cultivated in hydroponics

Christopher SheridanP DepuydtMadelena De RoChristophe PetitEllen Van GysegemPatricia DelaereM DixonM StasiakSB AciksözE Frossard et al.

A1 Journal Article in MICROBIAL ECOLOGY

Telomeres and atherosclerosis : the intricate pursuit of mechanistic insight through epidemiology

Tim De MeyerMarc De Buyzere

Editorial material

Virus detection in methylation-enriched DNA sequencing data

Klaas MensaertTim De MeyerOlivier Thas

2016

A genome-wide search for epigenetically regulated genes in zebra finch using MethylCap-seq and RNA-seq

Sandra SteyaertJolien DiddensJeroen GalleEllen De MeesterSarah De KeulenaerAntje BakkerNina Sohnius-WilhelmiCarolina Frankl-VilchesAnnemie Van der LindenWim Van Criekinge et al.

A1 Journal Article in SCIENTIFIC REPORTS

Developing bioinformatics applications for the analysis of epigenetic next-generation sequencing data

Sandra SteyaertTim De MeyerWim Van CriekingeWim Vanden Berghe

Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2/3

A BoersR WangRW van LeeuwenHG KlipGH de BockH HollemaWim Van CriekingeTim De MeyerSimon DenilAGJ van der Zee et al.

A1 Journal Article in CLINICAL EPIGENETICS

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

Grant D StewartThomas PowlesChristophe Van NesteAlison MeynertFiach O'MahonyAlexander LairdDieter DeforceFilip Van NieuwerburghGeert TrooskensWim Van Criekinge et al.

A1 Journal Article in ONCOTARGET

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma

Rong WangRobert W van LeeuwenAniek BoersHarry G KlipTim De MeyerRenske DM SteenbergenWim Van CriekingeAte GJ van der ZeeEd SchuuringG Bea A Wisman

A1 Journal Article in ONCOTARGET

Identification and validation of WISP1 as an epigenetic regulator of metastasis in oral squamous cell carcinoma

Martijn JAM ClausenLieuwe J MelchersMirjam F MastikLorian Slagter-MenkemaHarry JM GroenBernard FAM van der LaanWim Van CriekingeTim De MeyerSimon DenilG Bea A Wisman et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Identification of long non-coding RNAs involved in neuronal development and intellectual disability

Eva D'haeneEva JacobsPieter-Jan VoldersTim De MeyerBjörn MentenSarah Vergult

A1 Journal Article in SCIENTIFIC REPORTS

Identification of long non-coding RNAs involved in neuronal development and intellectual disability

Eva D'haeneEva JacobsPieter-Jan VoldersTim De MeyerBjörn MentenSarah Vergult

Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile

Tjinta BrinkhuizenMichel van GeelSimon DenilTim De MeyerNicole WJ Kelleners-SmeetsPeter JFM LohuisFrank. JP HoebersVéronique JL WinnepenninckxMaurice AM van SteenselKlara Mosterd

A1 Journal Article in EXPERIMENTAL DERMATOLOGY

Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients

Teofila SeremetAlexander KochYanina JansenMax SchreuerSofie WilgenhofVéronique Del MarmolDanielle LiènardKris ThielemansKelly SchatsMark Kockx et al.

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

RAB25 expression is epigenetically downregulated in oral and oropharyngeal squamous cell carcinoma with lymph node metastasis

MJAM ClausenLJ MelchersMF MastikL Slagter-MenkemaHJM GroenBFAM van der LaanWim Van CriekingeTim De MeyerSimon DenilB van der Vegt et al.

A1 Journal Article in EPIGENETICS

Telomeres and atherosclerosis : the attrition of an attractive hypothesis

Ernst RietzschelSofie BekaertTim De Meyer

Editorial material

2015

Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening

Brody HolohanTim De MeyerKimberly BattenMassimo ManginoSteven C HuntSofie BekaertMarc De BuyzereErnst RietzschelTim D SpectorWoodring E Wright et al.

A1 Journal Article in AGING CELL

Different approaches to measuring gene expression and DNA methylation and their application in cancer research

Alexander KochWim Van CriekingeTim De MeyerGerben Menschaert

Effect of sunitinib treatment on mutations and methylation in metastatic renal cancer

Grant StewartChristophe Van NesteAlison MeynertColin SempleFinch O'MahonyAlexander LairdAlan MackayGeert TrooskensWim Van CriekingeTim De Meyer et al.

Epigenetic profiling of cardiovascular ageing

Simon DenilTim De MeyerWim Van CriekingeSofie Bekaert

Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison

Tim De MeyerPierre BadyGeert TrooskensSebastian KurscheidJocelyne BlochJohan M KrosJohannes A HainfellnerRoger StuppMauro DelorenziMonika E Hegi et al.

A1 Journal Article in SCIENTIFIC REPORTS

Identification of a predictive signature based on immunohistochemical (IHC), RNA-seq and epigenetic profiling of melanoma metastases for response to ipilimumab-based immunotherapy

Teofila SeremetAlexander KochSofie WilgenhofMax SchreuerYanina JansenDanielle LienardVeronique Del MarmolKris ThielemansNicolas Van BarenPierre Coulie et al.

Is Southern blotting necessary to measure telomere length reproducibly?: authors' response to: Commentary: The reliability of telomere length measurements

Carmen M Martin-RuizDuncan BairdLaureline RogerPetra BoukampDamir KrunicRichard CawthonMartin M DokterPim Van Der HarstSofie BekaertTim De Meyer et al.

Editorial material

MEXPRESS : visualizing expression, DNA methylation and clinical TCGA data

Alexander KochTim De MeyerJana JeschkeWim Van Criekinge

A1 Journal Article in BMC GENOMICS

Mining for viral fragments in methylation enriched sequencing data

Klaas MensaertWim Van CriekingeOlivier ThasEd SchuuringRenske DM SteenbergenG Bea A WismanTim De Meyer

A1 Journal Article in FRONTIERS IN GENETICS

Possible technical and biological explanations for the 'parental telomere length inheritance discrepancy' enigma

Tim De MeyerDan TA Eisenberg

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

PROTEOFORMER : deep proteome coverage through ribosome profiling and MS integration

Jeroen CrappéElvis NdahAlexander KochSandra SteyaertDaria FijalkowskaSarah De KeulenaerEllen De MeesterTim De MeyerWim Van CriekingePetra Van Damme et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Reproducibility of telomere length assessment : an international collaborative study

Carmen M Martin-RuizDuncan BairdLaureline RogerPetra BoukampDamir KrunicRichard CawthonMartin M DokterPim van der HarstSofie BekaertTim De Meyer et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Reproducibility of telomere length assessment: authors' response to Damjan Krstajic and Ljubomir Buturovic

Carmen M Martin-RuizDuncan BairdLaureline RogerPetra BoukampDamir KrunicRichard CawthonMartin M DokterPim Van der HarstSofie BekaertTim De Meyer et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

2014

A non-genetic, epigenetic-like mechanism of telomere length inheritance?

Tim De MeyerKatrien VandepitteSimon DenilMarc De BuyzereErnst RietzschelSofie Bekaert

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

Arterial stiffness and influences of the metabolic syndrome: a cross-countries study

Angelo ScuteriPedro G CunhaE Agabiti RoseiJolita BadariereSofie BekaertJohn R CockcroftJorge CotterFrancesco CuccaMarc De BuyzereTim De Meyer et al.

A1 Journal Article in ATHEROSCLEROSIS

Bacterial diversity assessment in Antarctic terrestrial and aquatic microbial mats : a comparison between bidirectional pyrosequencing and cultivation

Bjorn TytgatElie VerleyenDagmar ObbelsKarolien PeetersAaike De WeverSofie D'hondtTim De MeyerWim Van CriekingeWim VyvermanAnne Willems

A1 Journal Article in PLOS ONE

Gender and telomere length: systematic review and meta-analysis

Michael GardnerDavid BannLaura WileyRachel CooperRebecca HardyDorothea NitschCarmen Martin-RuizPaul ShielsAavan Aihie SayerMichelangela Barbieri et al.

A1 Journal Article in EXPERIMENTAL GERONTOLOGY

Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Marco MediciEleonora PorcuGiorgio PistisAlexander TeumerSuzanne J BrownRichard A JensenRajesh RawalGREET ROEFTheo S PlantingaSita H Vermeulen et al.

A1 Journal Article in PLOS GENETICS

Next-generation technologies and data analytical approaches for epigenomics

Klaas MensaertSimon DenilGeert TrooskensWim Van CriekingeOlivier ThasTim De Meyer

A1 Journal Article in ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

On cross-sectional associations of leukocyte telomere length with cardiac systolic, diastolic and vascular function: the Asklepios study

Simon DenilErnst RietzschelMarc De BuyzereCaroline Van daelePatrick SegersDirk De BacquerWim Van CriekingeSofie BekaertThierry GillebertTim De Meyer

A1 Journal Article in PLOS ONE

Rapid genetic adaptation precedes the spread of an exotic plant species

Katrien VandepitteTim De MeyerKenny HelsenKasper Van AckerIsabel Roldán-RuizJoachim MergeayOlivier Honnay

A1 Journal Article in MOLECULAR ECOLOGY

SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data

Sandra SteyaertWim Van CriekingeAyla De PaepeSimon DenilKlaas MensaertKatrien VandepitteWim Vanden BergheGeert TrooskensTim De Meyer

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Systemic suppression of the shoot metabolism upon rice root nematode infection

Tina KyndtSimon DenilLander BautersWim Van CriekingeTim De Meyer

A1 Journal Article in PLOS ONE

ViVar: a comprehensive platform for the analysis and visualization of structural genomic variation

Tom SanteSarah VergultPieter-Jan VoldersWigard P KloostermanGeert TrooskensKatleen De PreterAnnelies DheedeneFranki SpelemanTim De MeyerBjörn Menten

A1 Journal Article in PLOS ONE

2013

Addition of a novel, protective family history category allows better profiling of cardiovascular risk and atherosclerotic burden in the general population: the Asklepios study

Caroline Van daeleTim De MeyerMarc De BuyzereThierry GillebertSimon DenilSofie BekaertJulio Chirinos MedinaPatrick SegersGui De BackerDirk De Bacquer et al.

A1 Journal Article in PLOS ONE

Alterations of immune response of non-small lung cancer with azacytidine

John WrangleWei WangAlexander KochHariharan EaswaranHelai P MohammadFrank VendettiWim Van CriekingeTim De MeyerZhengzong DuPrincy Parsana et al.

A1 Journal Article in ONCOTARGET

An epigenomic next-generation sequencing approach to identify predictive markers for PARP inhibitor response in breast cancer cells

Tim De MeyerGeert TrooskensMascha K WibbeSebastian B BartmannManon van EngelandWim Van CriekingeVivianne C Tjan-HeijnenRuth KnüchelJürgen Veeck

Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones

GREET ROEFErnst RietzschelTim De MeyerSofie BekaertMarc De BuyzereCaroline Van daeleKaatje ToyeJean KaufmanYouri Taes

A1 Journal Article in CLINICA CHIMICA ACTA

Associations of rs4704397 in phosphodiesterase 8B with thyrotropin and thyroid hormone concentrations

GREET ROEFErnst RietzschelTim De MeyerSofie BekaertMarc De BuyzereJean KaufmanYouri Taes

A1 Journal Article in THYROID

Family history of cardiovascular disease and offspring echocardiographic left ventricular structure and function: the Asklepios study

Caroline Van daeleTim De MeyerMarc De BuyzereThierry GillebertSimon DenilSofie BekaertJulio Chirinos MedinaGui De BackerDirk De BacquerErnst Rietzschel

A1 Journal Article in JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing

Tim De MeyerEvi MampaeyMichaël VlemmixSimon DenilGeert TrooskensJean-Pierre RenardSarah De KeulenaerPierre DehanGerben MenschaertWim Van Criekinge

A1 Journal Article in PLOS ONE

SNP discovery using paired-end RAD-tag sequencing on pooled genomic DNA of Sisymbrium austriacum (Brassicaceae)

K VandepitteO HonnayJ MergeayP BreyneIsabel Roldán-RuizTim De Meyer

A1 Journal Article in MOLECULAR ECOLOGY RESOURCES

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue : a preliminary study

Claudina Perez NovoYuan ZhangSimon DenilGeert TrooskensTim De MeyerWim Van CriekingePaul Van CauwenbergeLuo ZhangClaus Bachert

A1 Journal Article in ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY

The CpG island methylator phenotype: what's in a name?

Laura AE HughesVeerle MelotteJoachim De SchrijverMichiel de MaatVincent THBM SmitJudith VMG BovéePim J FrenchPiet A van den BrandtLeo J SchoutenTim De Meyer et al.

A1 Journal Article in CANCER RESEARCH

The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer

Kevin SharpeGrant D StewartAlan MackayChristophe Van NesteCharlotte RofeDan BerneyIrfan KayaniAxel BexElaine WanFiach C O'Mahony et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

The impact of extensive clonal growth on fine-scale mating patterns: a full paternity analysis of a lily-of-the-valley population (Convallaria majalis)

Katrien VandepitteTim De MeyerHans JacquemynIsabel Roldán-RuizOlivier Honnay

A1 Journal Article in ANNALS OF BOTANY

Transcriptional analysis through RNA sequencing of giant cells induced by Meloidogyne graminicola in rice roots

Hongli JiGodelieve GheysenSimon DenilKeith LindseyJennifer F ToppingKamrun NaharAnnelies HaegemanWinnok De VosGeert TrooskensWim Van Criekinge et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

2012

Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium

Gary F MitchellGermaine C VerwoertKirill V TarasovAaron IsaacsAlbert V Smith. YasminErnst RietzschelToshiko TanakaYongmei LiuAfshin Parsa et al.

A1 Journal Article in CIRCULATION-CARDIOVASCULAR GENETICS

Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells

Khalil Abou-El-ArdatPieter MonsieursNataša AnastasovMike AtkinsonHanane DerradjiTim De MeyerSofie BekaertWim Van CriekingeSarah Baatout

A1 Journal Article in MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

No shorter telomeres in subjects with a family history of cardiovascular disease in the Asklepios Study

Tim De MeyerCaroline Van daeleMarc De BuyzereSimon DenilDirk De BacquerPatrick SegersLuc CoomanGui De BackerThierry GillebertSofie Bekaert et al.

A1 Journal Article in ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Screening of soy and milk protein hydrolysates for their ability to activate the CCK1 receptor

Dorien StaljanssensJohn Van CampAnnelies BillietTim De MeyerNadin Al ShukorWinnok De VosGuy Smagghe

A1 Journal Article in PEPTIDES

Transcriptional reprogramming by root knot and migratory nematode infection in rice

Tina KyndtSimon DenilAnnelies HaegemanGeert TrooskensLander BautersWim Van CriekingeTim De MeyerGodelieve Gheysen

A1 Journal Article in NEW PHYTOLOGIST

Transcriptome analysis of rice mature root tissue and root tips in early development by massive parallel sequencing

Tina KyndtSimon DenilAnnelies HaegemanGeert TrooskensTim De MeyerWim Van CriekingeGodelieve Gheysen

A1 Journal Article in JOURNAL OF EXPERIMENTAL BOTANY

2011

A non-parametric method to assess the presence of significant DNA-methylation in enrichment-based NGS data

Klaas MensaertGeert TrooskensWim Van CriekingeOlivier ThasTim De Meyer

Charting the methylome

Geert TrooskensTim De MeyerSimon DenilWim Van Criekinge

Epigenetic, metabolic and signal transduction pathways involved in radiation response of normal and transformed thyrocytes

Khalil AbouelaradatWim Van CriekingeSarah BaatoutTim De MeyerSofie Bekaert

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Louise V WainGermaine C VerwoertPaul F O'ReillyGang ShiToby JohnsonAndrew D JohnsonMurielle BochudKenneth M RicePeter HennemanAlbert V Smith et al.

A1 Journal Article in NATURE GENETICS

PROKAR‐SEQ: an analysis and visualization framework for next‐generation sequencing based quantification of prokaryotic communities

Joachim De SchrijverPieter-Jan VoldersFrederiek-Maarten KerckhofDagmar ObbelsElie VerleyenWim VyvermanTim De MeyerWim Van Criekinge

Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system

Khalil Abou-El-ArdatHanane DerradjiWinnok De VosTim De MeyerSofie BekaertWim Van CriekingeSarah Baatout

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Telomere length and cardiovascular aging: the means to the ends?

Tim De MeyerErnst RietzschelMarc De BuyzereWim Van CriekingeSofie Bekaert

A1 Journal Article in AGEING RESEARCH REVIEWS

Telomere length integrates psychological factors in the successful aging story, but what about the biology?

Editorial material

2010

A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE genetics study

Ian BuysschaertKathryn F CarruthersDonald R DunbarGilian PeutemanErnst RietzschelAnn BelmansAnn HedleyTim De MeyerAndrzej BudajFrans Van de Werf et al.

A1 Journal Article in EUROPEAN HEART JOURNAL

Evaluation of standard and advanced preprocessing methods for the univariate analysis of blood serum 1H-NMR spectra

Tim De MeyerDavy SinnaeveBjörn Van GasseErnst RietzschelMarc De BuyzereMichel LangloisSofie BekaertJosé MartinsWim Van Criekinge

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Patterns of sex ratio variation and genetic diversity in the dioecious forest perennial Mercurialis perennis

Katrien VandepitteOlivier HonnayTim De MeyerHans JacquemynIsabel Roldán-Ruiz

A1 Journal Article in PLANT ECOLOGY

2009

Chromosome 9p21 Polymorphism Interacts With Waist-to-Hip Ratio in Carotid Plaque

Ian BuysschaertErnst RietzschelNatacha LaysBart ClaesSofie BekaertPeter VerhammePatrick SegersTim De MeyerDirk De BacquerThierry Gillebert et al.

E2Fs mediate a fundamental cell-cycle deregulation in high-grade serous ovarian carcinomas

Tim De MeyerIngrid TGW BijsmansKoen Van de VijverSofie BekaertJan OostingWim Van CriekingeManon van EngelandNathalie LG Sieben

A1 Journal Article in JOURNAL OF PATHOLOGY

External X-irradiation causes a decrease in the proliferation of two papillary thyroid carcinoma cell lines with no significant increase in cell death

Khalil Abou-El-ArdatHanane DerradjiSofie BekaertTim De MeyerWim Van CriekingeSarah Baatout

High content analysis of human fibroblast cell cultures after exposure to space radiation

Birger DieriksWinnok De VosGeert MeesenKaat Van OostveldtTim De MeyerMyriam GhardiSarah BaatoutPatric Van Oostveldt

A1 Journal Article in RADIATION RESEARCH

Systemic telomere length and preclinical atherosclerosis : the Asklepios study

Tim De MeyerErnst RietzschelMarc De BuyzereMichel LangloisDirk De BacquerPatrick SegersPIET VAN DAMMEGui De BackerPatric Van OostveldtWim Van Criekinge et al.

A1 Journal Article in EUROPEAN HEART JOURNAL

2008

De evaluatie van telomeerlengte als biomerker voor veroudering in de Asklepiosstudie

Tim De MeyerWim Van Criekinge

Genrisk-T project: response of the TPC-1 papillary thyroid carcinoma cell line to a range of low to high doses of irradiation

K Abou-El-ArdatH DerradjiSofie BekaertTim De MeyerWim Van CriekingeS Baatout

A4 Journal Article in COMMUNICATIONS IN AGRICULTURAL AND APPLIED BIOLOGICAL SCIENCES

Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects

Hanane DerradjiSofie BekaertTim De MeyerPaul JacquetKhalil AbouelaradatMyriam GhardiArlette MichauxSarah Baatout

A1 Journal Article in DEVELOPMENTAL BIOLOGY

Lower red blood cell counts in middle-aged subjects with shorter peripheral blood leukocyte telomere length

Tim De MeyerMarc De BuyzereMichel LangloisErnst RietzschelPeter CassimanDirk De BacquerPatric Van OostveldtGui De BackerThierry GillebertWim Van Criekinge et al.

A1 Journal Article in AGING CELL

NMR-based characterization of metabolic alterations in hypertension using an adaptive, intelligent binning algorithm

Tim De MeyerDavy SinnaeveBjörn Van GasseElena TsiporkovaErnst RietzschelMarc De BuyzereThierry GillebertSofie BekaertJosé MartinsWim Van Criekinge

A1 Journal Article in ANALYTICAL CHEMISTRY

PubMeth : a cancer methylation database combining text-mining and expert annotation

Maté OngenaertLeander Van NesteTim De MeyerGerben MenschaertSofie BekaertWim Van Criekinge

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Pubmeth: reviewed methylation database in cancer based on text-mining

Maté OngenaertLeander Van NesteTim De MeyerGerben MenschaertSofie BekaertWim Van Criekinge

Studying telomeres in a longitudinal population based study

Tim De MeyerErnst RietzschelMarc De BuyzereWim Van CriekingeSofie Bekaert

A1 Journal Article in Frontiers in Bioscience

Telomere biology in giant cell tumour of bone

Ramses ForsythGitte De BoeckSofie BekaertTim De MeyerAHM TaminiauDirk UyttendaeleHendrik RoelsMarleen PraetPCW Hogendoorn

A1 Journal Article in JOURNAL OF PATHOLOGY

2007

Paternal age at birth is an important determinant of offspring telomere length

Tim De MeyerErnst RietzschelMarc De BuyzereDirk De BacquerWim Van CriekingeGui De BackerThierry GillebertPatric Van OostveldtSofie Bekaert

A1 Journal Article in HUMAN MOLECULAR GENETICS

Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease

Sofie BekaertTim De MeyerErnst RietzschelMarc De BuyzereDirk De BacquerMichel LangloisPatrick SegersLuc CoomanPiet Van DammePeter Cassiman et al.

A1 Journal Article in AGING CELL

2006

Reference values and basic determinants of telomere length in a large middle-aged population

Tim De MeyerErnst RietzschelMarc De BuyzereThierry GillebertPatric Van OostveldtSofie Bekaert

2005

Telomere attrition as ageing biomarker

Sofie BekaertTim De MeyerPatric Van Oostveldt

A1 Journal Article in ANTICANCER RESEARCH

Telomere length versus hormonal and bone mineral status in healthy elderly men

Sofie BekaertI Van PottelberghTim De MeyerHans-Georg ZmierczakJean KaufmanPatric Van OostveldtStefan Goemaere

A1 Journal Article in MECHANISMS OF AGEING AND DEVELOPMENT

Telomere shortening is associated with malformation in p53-deficient mice after irradiation during specific stages of development

Sofie BekaertHanane DerradjiTim De MeyerArlette MichauxJasmine BusetMieke NeefsMax MergeayPaul JacquetPatric Van OostveldtSarah Baatout

A1 Journal Article in DNA REPAIR

2004

Seizing human biological age

Sofie BekaertTim De MeyerErnst RietzschelMarc De BuyzereS BAATOUTThierry GillebertPatric Van Oostveldt

Sizing chromosome termini: a valuable biomarker in aging phenotypes

Sofie BekaertI VAN POTTELBERGHErnst RietzschelTim De MeyerMarc De BuyzereThierry GillebertPatric Van Oostveldt

Telomere attrition rate: a valuable biomarker in aging phenotypes

Sofie BekaertErnst RietzschelInge Van PottelberghStefan GoemaereTim De MeyerMarc De BuyzereJean KaufmanThierry GillebertPatric Van Oostveldt

Telomere attrition rate: a valuable biomarker in aging phenotypes

Sofie BekaertErnst RietzschelInge Van PottelberghStefan GoemaereTim De MeyerMarc De BuyzereJean KaufmanThierry GillebertPatric Van Oostveldt