Research Explorer

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Researcher

Thomas Vanwolleghem

Awards & Distinctions

13 Results

2012

Mitochondrial cardiotoxicity of a prototype HCV NS3-protease inhibitor is characterized by a specific electrocardiographic signature in mice

Thomas VanwolleghemEva Van BraeckelJoél SmetBi-Sheng LiuPhilip MeulemanHarry L JanssenTania RoskamsRudy Van CosterRita De VosGeert Leroux-Roels

2011

In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

Philip MeulemanJens BukhLieven VerhoyeAliasghar Farhoudi MoghadamThomas VanwolleghemRichard Y WangIsabelle DesombereHarvey AlterRobert H PurcellGeert Leroux-Roels

A1 Journal Article in HEPATOLOGY

2010

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice

Thomas VanwolleghemLouis LibbrechtBettina E HansenIsabelle DesombereTania RoskamsPhilip MeulemanGeert Leroux-Roels

A1 Journal Article in JOURNAL OF HEPATOLOGY

2009

Experimental models for hepatitis C viral infection

Andre BoonstraLuc van der LaanThomas VanwolleghemHarry Janssen

A1 Journal Article in Hepatology

2008

ANTI-CD81 ANTIBODIES CAN PREVENT A HEPATITIS C VIRUS INFECTION IN VIVO

Philip MeulemanJoseph HesselgesserMatthew PaulsonThomas VanwolleghemIsabelle DesombereHans ReiserGeert Leroux-Roels

Anti-CD81 Antibodies Can Prevent a Hepatitis C Virus Infection In Vivo

Philip MeulemanJoseph HesselgesserMatthew PaulsonThomas VanwolleghemIsabelle DesombereIlans ReiserGeert Leroux-Roels

A1 Journal Article in HEPATOLOGY

Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain

Thomas VanwolleghemJ BUKHPhilip MeulemanIsabelle DesombereJC MEUNIERH ALTERRH PURCELLGeert Leroux-Roels

A1 Journal Article in HEPATOLOGY

2007

Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial

Isabel Leroux-RoelsAstrid BorkowskiThomas VanwolleghemMamadou DrameFrédéric ClementEliane HonsJeanne-Marie DevasterGeert Leroux-Roels

A1 Journal Article in LANCET

Scavenger receptor BI and BII expression levels modulate hepatitis C virus infectivity

J GROVET HUBYZ STAMATAKIThomas VanwolleghemPhilip MeulemanM FARQUHARA SCHWARZM MOREAUJS OWENGeert Leroux-Roels et al.

A1 Journal Article in JOURNAL OF VIROLOGY

Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse

Thomas VanwolleghemPhilip MeulemanLouis LibbrechtTania RoskamsRita De VosGeert Leroux-Roels

A1 Journal Article in GASTROENTEROLOGY

2006

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

BD LINDENBACHPhilip MeulemanA PLOSSThomas VanwolleghemAJ SYDERJA MCKEATINGRE LANFORDSM FEINSTONEME MAJORGeert Leroux-Roels et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2004

Efavirenz-associated Stevens-Johnson syndrome

R COLEBUNDERSThomas VanwolleghemP MEURRENSF MOERMAN

A1 Journal Article in INFECTION

Lopinavir/ritonavir- and indinavir-induced thrombocytopenia in a patient with HIV infection

R COLEBUNDERSC DE SCHACHTThomas VanwolleghemS CALLENS

A1 Journal Article in INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES