Research Explorer

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Researcher

Thijs Van de Vyver

Awards & Distinctions

8 Results

2023

The alpha-adrenergic antagonist prazosin promotes cytosolic siRNA delivery from lysosomal compartments

Thijs Van de VyverCristina MunteanIuliia EfimovaDmitri KryskoLynn De BackerStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2022

Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics

Thijs Van de VyverStefaan De SmedtKoen Raemdonck

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

2021

Hydrogel-induced cell membrane disruptions enable direct cytosolic delivery of membrane-impermeable cargo

Jelter Van HoeckThijs Van de VyverAranit HarizajGlenn GoetgelukPieterjan MerckxJing LiuMike WelsFélix SauvageHerlinde De KeersmaeckerChristian Vanhove et al.

A1 Journal Article in ADVANCED MATERIALS

Old drugs with new tricks : repurposing small molecules to promote lysosomal escape of small nucleic acid therapeutics

Thijs Van de VyverKoen RaemdonckStefaan De Smedt

Surfactant protein B promotes cytosolic SiRNA delivery by adopting a virus-like mechanism of action

Roberta GuagliardoLore HermanJelle PendersAgata ZamborlinHerlinde De KeersmaeckerThijs Van de VyverSandrine VerstraetenPieterjan MerckxMarie-Paule Mingeot-LeclercqMercedes Echaide et al.

A1 Journal Article in ACS NANO

2020

Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner

Thijs Van de VyverBram BogaertLynn De BackerFreya JorisRoberta GuagliardoJelter Van HoeckPieterjan MerckxSerge Van CalenberghSrinivas RamishettiDan Peer et al.

A1 Journal Article in ACS NANO

2018

Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells

Freya JorisLynn De BackerThijs Van de VyverChiara BastiancichStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2017

Glycation in human fingernail clippings using ATR-FTIR spectrometry, a new marker for the diagnosis and monitoring of diabetes mellitus

Renaat CoopmanThijs Van de VyverAntoine Sadiki KishabongoPhilippe KatchungaElisabeth H Van AkenJustin CikomolaTinne MonteyneMarijn SpeeckaertJoris Delanghe

A1 Journal Article in CLINICAL BIOCHEMISTRY