Research Explorer

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Researcher

Tamara Jarayseh

Publications & Research Data

Awards & Distinctions

17 Results

2025

Decoding Phenotypic Variability in Osteogenesis Imperfecta: Zebrafish as a Model for Molecular and Ultrastructural Insights

Sophie DebaenstLauren SahdCaitlin DebaeneTamara JaraysehHanna De SaffelJan Willem BekWouter SteyaertDelphi Van HaverSara DufourFrancis Impens et al.

2024

Bmpr1aa modulates the severity of the skeletal phenotype in an fkbp10-deficient Bruck syndrome zebrafish model

Tamara JaraysehSophie DebaenstHanna De SaffelToon RosseelMauro Alessio MilazzoJan Willem BekDavid M HudsonFilip Van NieuwerburghYannick GansemansIván Josipovic et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility

Sophie DebaenstTamara JaraysehHanna De SaffelJan Willem BekMatthieu BooneIván JosipovicPierre KibleurRonald Y KwonPaul CouckeAndy Willaert

A2 Journal Article in ELIFE

Unraveling phenotypic variability and disease manifestations in brittle bone disorders

Tamara JaraysehPaul CouckeAndy Willaert

2023

A tapt1 knock-out zebrafish line with aberrant lens development and impaired vision models human early-onset cataract

Tamara JaraysehBrecht GuillemynHanna De SaffelJan Willem BekDelfien SyxSofie SymoensYannick GansemansFilip Van NieuwerburghSujatha JagadeeshJayarekha Raja et al.

A1 Journal Article in HUMAN GENETICS

Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for Osteogenesis Imperfecta

Sophie DebaenstHanna De SaffelJan Willem BekAdelbert De ClercqTamara JaraysehLauren SahdPaul CouckeAndy Willaert

Identification of modifier genes underlying intra-familial phenotypic variability in zebrafish OI models using whole exome sequencing and linkage analysis

Tamara JaraysehAdelbert De ClercqToon RosseelMauro Alessio MilazzoAndy WillaertPaul Coucke

Syntaxin 18 defects in human and zebrafish unravel key roles in early cartilage and bone development

Brecht GuillemynHanna De SaffelJan Willem BekPiyanoot TapaneeyaphanAdelbert De ClercqTamara JaraysehSophie DebaenstAndy WillaertRiet De RyckePeter H. Byers et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Syntaxin-18 defects in human and zebrafish cause traffic jams and unravel key roles in early bone development

Brecht GuillemynHanna De SaffelJan Willem BekPiyanoot TapaneeyaphanAdelbert De ClercqTamara JaraysehSophie DebaenstAndy WillaertPeter ByersPaul Coucke et al.

Unraveling of the ultrastructural features that determine the variability in phenotypic severity in different dominant forms of OI, using the zebrafish as a model

Lauren SahdCaitlin DebaeneSophie DebaenstTamara JaraysehHanna De SaffelMyriam ClaeysJan Willem BekCharlotte GistelinckFrans RodenburgPhil Salmon et al.

2022

A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract

Tamara JaraysehBrecht GuillemynHanna De SaffelJan Willem BekSujatha JagadeeshSofie SymoensFransiska MalfaitDelfien SyxFilip Van NieuwerburghYannick Gansemans et al.

A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract

Tamara JaraysehBrecht GuillemynHanna De SaffelJan Willem BekSujatha JagadeeshSofie SymoensFransiska MalfaitDelfien SyxFilip Van NieuwerburghYannick Gansemans et al.

Crispant screening in zebrafish as a promising approach for rapid functional screening of osteoporosis candidate genes and known genes for Osteogenesis Imperfecta

Sophie DebaenstHanna De SaffelJan Willem BekAdelbert De ClercqTamara JaraysehLauren SahdPaul CouckeAndy Willaert

2021

Identification of modifier genes underlying intra-familial phenotypic variability in zebrafish OI models using whole exome sequencing (WES) and linkage analysis

Tamara JaraysehAdelbert De ClercqToon RosseelMauro Alessio MilazzoAndy WillaertPaul Coucke

2020

Genomic analysis of inherited hearing loss in the Palestinian population

Amal Abu RayyanLara KamalSilvia CasadeiZippora BrownsteinFouad ZahdehHashem ShahinChristina CanavatiDima DweikTamara JaraysehGrace Rabie et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicase-inactivating BRIP1 mutation yields Fanconi anemia with microcephaly and other congenital abnormalities

Lara KamalSarah B. PierceChristina CanavatiAmal Abu RayyanTamara JaraysehOrit LobelSuhair LolasBarbara M. NorquistGrace RabieFouad Zahdeh et al.

A2 Journal Article in COLD SPRING HARBOR MOLECULAR CASE STUDIES

2017

Genomic analysis of inherited breast cancer among Palestinian women : genetic heterogeneity and a founder mutation in TP53

Suhair Lolas HamamehPaul RenbaumLara KamalDima DweikMohammad SalahatTamara JaraysehAmal Abu RayyanSilvia CasadeiJessica B. MandellSuleyman Gulsuner et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER