Research Explorer

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Researcher

Sylvie Rottey

191 Results

2021

A phase 1a/1b trial of CSF-1R inhibitor LY3022855 in combination with durvalumab or tremelimumab in patients with advanced solid tumors

Gerald S. FalchookMarc PeetersSylvie RotteyLuc Y. DirixRadka ObermannovaJonathan E. CohenRuth PeretsRonnie Shapira FrommerTodd M. BauerJudy S. WangRichard D. CarvajalJoshua SabariSonya ChapmanWei ZhangBoris CalderonDaniel A. Peterson

U Journal Article in INVESTIGATIONAL NEW DRUGS

Effectiveness of adjunctive analgesics in head and neck cancer patients receiving curative (chemo-) radiotherapy : a systematic review

Tessa LefebvreLaura TackMichelle LyckeFréderic DuprezLaurence GoethalsSylvie RotteyLieselot CoolKoen Van EygenBrendon StubbsPatricia SchofieldHans PottelTom BoterbergPhilip Debruyne

A1 Journal Article in PAIN MEDICINE

Expected Medium- and Long-Term Impact of the COVID-19 Outbreak in Oncology

Concetta Elisa OnestiMarco TagliamentoGiuseppe CuriglianoNadia HarbeckRupert BartschHans WildiersVivianne Tjan-HeijnenMiguel MartinSylvie RotteyDaniele GeneraliMario CamponeMassimo CristofanilliLajos PusztaiMarc PeetersGuy BerchemJavier CortesThomas RuhstallerEva CiruelosHope S. RugoGuy Jerusalem

U Journal Article in JCO GLOBAL ONCOLOGY

Expected medium- and long-term impact of the COVID-19 outbreak in oncology

Concetta Elisa OnestiMarco TagliamentoGiuseppe CuriglianoNadia HarbeckRupert BartschHans WildiersVivianne Tjan-HeijnenMiguel MartinSylvie RotteyDaniele GeneraliMario CamponeMassimo CristofanilliLajos PusztaiMarc PeetersGuy BerchemJavier CortesThomas RuhstallerEva CiruelosHope S. RugoGuy Jerusalem

A2 Journal Article in JCO GLOBAL ONCOLOGY

Favorable survival for endonasal endoscopic resection in locally advanced sinonasal intestinal type adenocarcinoma: a long-term comparative study

Stijn De KeukeleireJens DebackerTijl VermassenFréderic DuprezPhilippe DeronWouter HuvenneDavid CreytensSylvie RotteyThibaut Van Zele

Immune Monitoring in Melanoma and Urothelial Cancer Patients Treated with Anti-PD-1 Immunotherapy and SBRT Discloses Tumor Specific Immune Signatures

Annabel MeiresonSimon TavernierSofie Van GassenNora SundahlAnnelies DemeyerMathieu SpaasVibeke KruseLiesbeth FerdinandeJo Van DorpeBenjamin HennartDelphine AllorgeFilomeen HaerynckKarel DecaesteckerSylvie RotteyYvan SaeysPiet OstLieve Brochez

U Journal Article in Cancers

Immune checkpoint inhibitors in treatment of soft-tissue sarcoma : a systematic review and meta-analysis

Michael SaerensNele BrusselaersSylvie RotteyAlexander DecruyenaereDavid CreytensLore Lapeire

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Immuno-oncological biomarkers for squamous cell cancer of the head and neck : current state of the art and future perspectives

Stijn De KeukeleireTijl VermassenElien HilgertDavid CreytensLiesbeth FerdinandeSylvie Rottey

A1 Journal Article in CANCERS

Managing viral hepatitis in cancer patients under immune checkpoint inhibitors : should we take the risk?

Stijn De KeukeleireTijl VermassenZahra Mosala NezhadTessa KerreVibeke KruseHans Van VlierbergheKarim VermaelenSylvie Rottey

A1 Journal Article in IMMUNOTHERAPY

Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a Phase 1 study

Philippe GevaertJarno De CraemerNatalie De RuyckSylvie RotteyJan de HoonPeter W. HellingsBram VolckaertKristof LesneuckJamie M. OrengoAmanda AtanasioMohamed A. KamalHisham AbdallahVishal KamatRobert DingmanMichelle DeVeauxDivya RameshLorah PerleeClaire Q. WangDavid WeinreichGary HermanGeorge D. YancopoulosMeagan P. O’Brien

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Safety and immunogenicity of LY3415244, a bispecific antibody against TIM-3 and PD-L1, in patients with advanced solid tumors

Matthew D. HellmannNicoletta BiviBoris CalderonToshio ShimizuBrant DelafontaineZhuqing Tina LiuAnna M. SzpurkaVictoria CopelandF. Stephen HodiSylvie RotteyPhilippe AftimosYongzhe PiaoLeena GandhiVioleta Regnier GalvaoChing Ching LeowToshihiko Doi

A1 Journal Article in CLINICAL CANCER RESEARCH

Safety and tolerability of topical polyhexamethylene biguanide : a randomised clinical trial in healthy adult volunteers

Vincenzo PapaIvanka van der MeulenSylvie RotteyGuy SalletJolanda OverweelNino AseroDarwin C MinassianJohn K G Dart

A1 Journal Article in BRITISH JOURNAL OF OPHTHALMOLOGY

Selective oral MEK1/2 inhibitor pimasertib : a phase I trial in patients with advanced solid tumors

Jean-Pierre DelordAntoine ItalianoAhmad AwadaPhilippe AftimosNadine HouédéCéleste LebbéCeline PagesThierry LesimpleMonica DinulescuJan H. M. SchellensSuzanne LeijenSylvie RotteyVibeke KruseRichard KeffordSandrine FaivreCarlos Gomez-RocaArmin ScheulerGiorgio MassiminiEric Raymond

A1 Journal Article in TARGETED ONCOLOGY

Selective oral MEK1/2 inhibitor pimasertib in metastatic melanoma : antitumor activity in a phase I, dose-escalation trial

Céleste LebbéAntoine ItalianoNadine HouédéAhmad AwadaPhilippe AftimosThierry LesimpleMonica DinulescuJan H. M. SchellensSuzanne LeijenSylvie RotteyVibeke KruseRichard KeffordEric RaymondSandrine FaivreCeline PagesCarlos Gomez-RocaArmin SchuelerSamantha GoodstalGiorgio MassiminiJean-Pierre Delord

A1 Journal Article in TARGETED ONCOLOGY

Tissue N-linked glycosylation as potential prognostic biomarker for biochemical recurrence-free survival

Tijl VermassenArne Van den BroeckNicolaas LumenNico CallewaertSylvie RotteyJoris Delanghe

A1 Journal Article in BIOMARKERS

Tumour infiltrating lymphocytes in oropharyngeal carcinoma: prognostic value and evaluation of a standardised method

Stijn J. De KeukeleireTijl VermassenAstrid De MeulenaerePhilippe DeronWouter HuvenneFréderic DuprezDavid CreytensJo Van DorpeSylvie RotteyLiesbeth Ferdinande

U Journal Article in Pathology

Verrucous hyperplasia and verrucous carcinoma in head and neck : use and benefit of methotrexate

Stijn De KeukeleireAstrid De MeulenaerePhilippe DeronWouter HuvenneFréderic DuprezOlivier BouckenoogheLiesbeth FerdinandeDavid CreytensSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

2020

'In-house' data on the outside : a mobile health approach

Qinlei HuangTami CrumleyChristina WaltersLiesbeth CluckersIngeborg HeirmanRadha RailkarGaurav BhatiaMatthew CantorChristopher BenkoElena S IzmailovaSylvie RotteyS Aubrey Stoch

A1 Journal Article in CLINICAL PHARMACOLOGY & THERAPEUTICS

A phase 1 study of mTORC1/2 inhibitor BI 860585 as a single agent or with exemestane or paclitaxel in patients with advanced solid tumors

Filippo de BraudJean-Pascal H. MachielsDaniela BoggianiSylvie RotteyMatteo DucaMarie LaruelleStefania SalvagniSilvia DamianLore LapeireMarcello TiseoAlexandre DermineMahmoud Ould-KaciJuergen BraungerJuliane RascherDaniela FischerJosef HoeflerGabriella L. MarianiSara Cresta

A1 Journal Article in CANCERS

A phase Ib study to evaluate RO7198457, an individualized Neoantigen Specific immunoTherapy (iNeST), in combination with atezolizumab in patients with locally advanced or metastatic solid tumors

Juanita S. LopezRoss CamidgeMarco IafollaSylvie RotteyMartin SchulerMatthew HellmannAni BalmanoukianLuc DirixMichael GordonRyan SullivanBrian S. HenickCharles DrakeKit WongPatricia LoRussoPatrick OttLawrence FongAglaia SchizaJeffery YachninChristian OttensmeierFadi BraitehJohanna BendellRom LeidnerGeorge FisherGuy JerusalemLaura Molenaar-KuijstenMarcus SchmidtScott A. LaurieRaid AljumailyAchim RittmeyerEelke GortIgnacio MeleroLars MuellerRachel SabadoPatrick TwomeyJack HuangManesh YadavJingbin ZhangFelicitas MuellerEvelyna DerhovanessianUgur SahinOezlem TuereciThomas Powles

A randomized phase II study of Nivolumab plus Ipilimumab versus standard of care in previously untreated and advanced non-clear cell renal cell carcinoma (Suniforecast)

Marit AhrensBernard EscudierEkaterini BoletiMarc-Oliver GrimmMarine Gross GoupirPilippe BarthelemyGwenaelle GravisJens BedekesPhilipp IvanyiAndrej PanicStefanie ZschaebitzSylvie NeyrieruBegona MelladoAnika BielTom WadellJose Pablo MarotoMargitta RetzMartin BoegemannSylvie RotteyJohn HaanenSjoukje OostingDaniel CastellanoArndt HartmannLothar Bergmann

Drug development from bench to bedside @UZGENT

Johan Vande WalleSylvie RotteyBram De Wilde

On-target pharmacodynamic activity of the PI3K inhibitor copanlisib in paired biopsies from patients with malignant lymphoma and advanced solid tumors

Franck MorschhauserJean-Pascal MachielsGilles SallesSylvie RotteySimon A. J. RuleDavid CunninghamFrederic PeyradeChristophe FruchartHendrik-Tobias ArkenauIsabelle GenvresseLi LiuKarl KoechertKui ShenChristoph KneipCarol E. PenaJoachim GrevelJun ZhangGalia CisternasSusanne ReschkeCamille GranvilAhmad Awada

A1 Journal Article in MOLECULAR CANCER THERAPEUTICS

Oncological care organisation during COVID-19 outbreak

Concetta Elisa OnestiHope S. RugoDaniele GeneraliMarc PeetersKhalil ZamanHans WildiersNadia HarbeckMiguel MartinMassimo CristofanilliJavier CortesVivianne Tjan-HeijnenSara A. HurvitzGuy BerchemMarco TagliamentoMario CamponeRupert BartschSabino De PlacidoFabio PuglisiSylvie RotteyVolkmar MüllerThomas RuhstallerJean-Pascal MachielsPierFranco ConteAhmad AwadaGuy Jerusalem

A1 Journal Article in ESMO OPEN

Phase 1 study of AMG 160, a half-life extended BITE (R) (bispecific T-cell engager) therapy targeting prostate-specific membrane antigen, in patients with metastatic castration-resistant prostate cancer

Tanya DorffMatthew RettigJean-Pascal MachielsMartijn LolkemaKaren AutioRichard GreilSylvie RotteyNabil AdraMark SalvatiShirley PoonDaniel TanGabor JuridaHosein Kouros-MehrKarim FizaziBen TranLisa Horvath

Phase I study of AMG 160, a half-life extended bispecific T-cell engager (HLE BiTE immune therapy) targeting prostate-specific membrane antigen, in patients with metastatic castration-resistant prostate cancer (mCRPC).

Ben TranLisa HorvathMatthew RettigKarim FizaziMartijn P. LolkemaTanya B. DorffRichard GreilJean-Pascal H. MachielsKaren A. AutioSylvie RotteyNabil AdraRohan GarjeFelicia RoncolatoScott T. TagawaShahrokh F. ShariatMark SalvatiShirley PoonHosein Kouros-Mehr

Radiologic extranodal extension and outcome in cN + D TNM-8 stage I human papillomavirus-mediated oropharyngeal cancer : in regard to Billfalk-Kelly et al.

Fréderic DuprezDavid CreytensWilfried De NevePhilippe DeronWouter HuvenneSylvie RotteyPeter Tomassen

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Safety, tolerability, and potential clinical activity of a glucocorticoid-induced TNF receptor-related protein agonist alone or in combination with nivolumab for patients with advanced solid tumors : a phase 1/2a dose-escalation and cohort-expansion clinical trial

Kimberley M HeinhuisMatteo CarlinoMarkus JoergerMassimo Di NicolaTarek MeniawySylvie RotteyVictor MorenoAnas GazzahJean-Pierre DelordLuis Paz-AresChristian BritschgiRussell J SchilderKenneth O'ByrneGiuseppe CuriglianoEmanuela RomanoPoliana PatahRui WangYali LiuGaurav BajajLillian L Siu

A1 Journal Article in JAMA ONCOLOGY

Targeting FGFR in bladder cancer : ready for clinical practice?

Stijn De KeukeleireDaan De MaeseneerCeline JacobsSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

2019

A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE)

Jean-Pascal MachielsRamon SalazarSylvie RotteyIgnacio DuranLuc DirixKaren GeboesChristine Wilkinson-BlancGillian PoverSimon AlvisBrian ChampionKerry FisherHilary McElwaine-JohnnJohn BeadleEmiliano Calvo

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

A phase II study of monalizumab in patients with recurrent/metastatic (RM) squamous cell carcinoma of the head and neck (SCCHN) : results of the I1 cohort of the EORTC-HNCG-1559 trial (UPSTREAM)

R GalotC Le TourneauE Saada-BouzidA DasteC EvenPR DebruyneS HenryS ZanettaA RuttenLF LicitraJ-L CanonM-C Kaminsky-ForrettP SpecenierSylvie RotteyL DirixT RaveloarivahyC Fortpied LefevreMBM VanlanckerA-S GovaertsJ-P Machiels

A phase Ia/b study of TIM-3/PD-L1 bispecific antibody in patients with advanced solid tumors

Matthew David HellmannToshio ShimizuToshihiko DoiF. Stephen HodiSylvie RotteyPhilippe Georges AftimosZhuqing Tina LiuNieves Velez de MendizabalAnna M. SzpurkaYongzhe PiaoBurkhard VangerowLeena GandhiChing Ching Leow

Algorithms for molecular testing in solid tumours

A. HébrantM. LammensC. Van den BroeckeN. D’HaeneJ. Van den OordA. VandersticheleA. DendoovenP. NevenK. PunieG. FlorisJoni Van der MeulenH. A. PoirelC. DoomsSylvie RotteyTom BoterbergLieve BrochezM. C. BurlacuG. CostanteDavid CreytensP. De PaepeR. De PauwnB. DecallonneF. DedeurwaerdereHannelore DenysLiesbeth FerdinandeR. ForsythM. GarmynT. GevaertJ. De GrèveE. GovaertsE. HaubenJ. KergerO. Kholmanskikh Van CriekingenV. KruseY. LalamiLore LapeireP. LefesvreJ. P. MachielsB. MaesG. MartensM. RemmelinkI. SalmonR. SciotS. TejparKoen Van de VijverL. Van de VoordeI. Van den BergheA. Van den BruelKatrien VandecasteeleL. VanwalleghemK. VermaelenR. SalgadoE. WautersB. WeynandE. Van ValckenborghG. RaicevicM. Van den BulckeP. Pauwels

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Brain metastasis and renal cell carcinoma : prognostic scores assessment in the era of targeted therapies

Ziad El AliSylvie RotteyPhilippe BarthelemyNuria KoteckiRuben Van PaemelDaniel DevrientAhmad AwadaThierry GilDiane PannierThomas RyckewaertWaissi WaisseJean-Baptiste ClavierNicolas PenelTijl Vermassen

A1 Journal Article in ANTICANCER RESEARCH

Chimeric antigen receptor-T cells for targeting solid tumors : current challenges and existing strategies

Lorraine SpringuelCaroline LonezBertrand AlexandreEric Van CutsemJean-Pascal H. MachielsMarc Van Den EyndeHans PrenenAlain HendliszLeila ShazaJavier CarrascoJean-Luc CanonMateusz OpyrchalKunle OdunsiSylvie RotteyDavid E. GilhamAnne FlamentFrederic F. Lehmann

A1 Journal Article in BIODRUGS

Comparison of immediate vs deferred cytoreductive nephrectomy in patients with synchronous metastatic renal cell carcinoma receiving sunitinib : the SURTIME randomized clinical trial

Axel BexPeter MuldersMichael JewettJohn WagstaffJohannes V van ThienenChristian U BlankRoland van VelthovenMaria del Pilar LagunaLori WoodHarm HE van MelickMaureen J AartsJB LattoufThomas PowlesIgle Jan de JongSylvie RotteyBertrand TombalSandrine MarreaudSandra ColletteLaurence ColletteJohn Haanen

A1 Journal Article in JAMA ONCOLOGY

European Federation for Exploratory Medicines Development Lyon Conference 2019 : the changing landscape of early medicines development : be prepared

Tim HardmanHenri CaplainSylvie RotteyDesiree DouglasSteffan StringerHildegard Sourgens

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Highlights in genitourinary cancers

Tijl VermassenSylvie Rottey

Importance of metastatic volume in prognostic models to predict survival in newly diagnosed metastatic prostate cancer

Sarah BuelensElise De BleserBert DhondtWesley VerlaKarel DecaesteckerPiet OstValerie FonteyneKathia De ManChloë StandaertSylvie RotteyNicolaas Lumen

A1 Journal Article in WORLD JOURNAL OF UROLOGY

Mobile health technology captures 'in-house' data on the outside : an assessment with pharmacological intervention

G BhatiaQ HuangT CrumleyC WaltersL CluckersI HeirmanL MixsonSylvie RotteyM CantorC BenkoS Stoch

N-Linked glycosylation and near-infrared spectroscopy in the diagnosis of prostate cancer

Tijl VermassenSander De BruyneJonas HimpeNicolaas LumenNico CallewaertSylvie RotteyJoris Delanghe

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phase 1 study evaluating the association of the cyclin-dependent kinase 4/6 inhibitor ribociclib and cetuximab in recurrent/metastatic p16-negative squamous cell carcinoma of the head and neck

Emmanuel SerontSandra SchmitzMatthias PapierAline van MaanenStéphanie HenryChristophe LonchaySylvie RotteyGabrielle van CaloenJean-Pascal Machiels

A1 Journal Article in FRONTIERS IN ONCOLOGY

Phase I open-label study evaluating the safety, pharmacokinetics, and preliminary efficacy of ABBV-181 and rovalpituzumab tesirine (ROVA-T) in patients with small cell lung cancer

E CalvoA SpiraH PrenenY OheSylvie RotteyA GazzahM MillwardV MorenoA ItalianoT AlankoK YohPA CassierT SetoD AfarS EnglertP KomarnitskyS LambertA ParikhG VosganianB Gao

Phase Ib study of talimogene laherparepvec (T-VEC) injection into liver metastases (LMs) in combination with intravenous (IV) atezolizumab in patients (pts) with metastatic triple negative breast cancer (TNBC) or colorectal cancer (CRC).

J. Randolph HechtArlene ChanMiguel MartinNicolas MachSara A. HurvitzSylvie RotteyUwe PelzerChunxu LiuEmily Chan

Policies influencing access to new targeted oncologic drugs in Ecuadorian hospitals : an interrupted time series analysis

Carlos DuránMonique ElseviersRobert Vander SticheleSylvie RotteyPatricia GranjaThierry Christiaens

A2 Journal Article in JOURNAL OF PHARMACEUTICAL HEALTH SERVICES RESEARCH

Prostate protein n-glycosylation profiling by means of DNA sequencer-assisted fluorophore-assisted carbohydrate electrophoresis

Tijl VermassenNico CallewaertSylvie RotteyJoris Delanghe

Bookchapter in Clinical applications of capillary electrophoresis : methods and protocols

Randomized phase 1 trial of pembrolizumab with neo-adjuvant versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma: Clinical and translational results

Piet OstNora SundahlG VandekerkhoveKarel DecaesteckerAnnabel MeiresonPieter De VisschereValerie FonteyneDaan De MaeseneerDries ReyndersEls GoetghebeurJo Van DorpeSofie VerbekeM AnnalaLieve BrochezKim Van der EeckenAW WyattSylvie Rottey

Randomized phase 1 trial of pembrolizumab with sequential versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma

Nora SundahlGillian VandekerkhoveKarel DecaesteckerAnnabel MeiresonPieter De VisschereValerie FonteyneDaan De MaeseneerDries ReyndersEls GoetghebeurJo Van DorpeSofie VerbekeMatti AnnalaLieve BrochezKim Van der EeckenAlexander W WyattSylvie RotteyPiet Ost

A1 Journal Article in EUROPEAN UROLOGY

Randomized phase I trial of pembrolizumab with neo-adjuvant versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma : clinical and translational results

Gillian VandekerkhoveNora SundahlKarel DecaesteckerAnnabel MeiresonPieter De VisschereValerie FonteyneDaan De MaeseneerDries ReyndersEls GoetghebeurJo Van DorpeSofie VerbekeMatti AnnalaLieve BrochezKim Van der EeckenAlexander William WyattSylvie RotteyPiet Ost

Surgical safety of cytoreductive nephrectomy following sunitinib : results from the multicentre, randomised controlled trial of immediate versus deferred nephrectomy (SURTIME)

Roderick Emile De BruijnPeter MuldersMichael A JewettJohn WagstaffJohan V Van ThienenChristian U BlankRoland Van VelthovenLori WoodHarm E van MelickMaureen J AartsJean B LattoufThomas PowlesIgle J De JongSylvie RotteyBetrand TombalSandrine MarreaudSandra ColletteLaurence ColletteJohn B HaanenAxel Bex

A1 Journal Article in EUROPEAN UROLOGY

The new first-in-human EMA guideline : disruptive or constructive? Outcomes from the first EUFEMED discussion forum

Kerstin Breithaupt-GröglerTim HardmanJan de HoonYves DonazzoloSylvie RotteyHildegard SourgensSteffan Stringer

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

To treat or not to treat? Managing comorbidities in cancer patients under immune checkpoint inhibition

Stijn De KeukeleireTijl VermassenGert De SchoenmakereVibeke KruseKarim VermaelenSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer : a phase 1 dose-escalation and dose-expansion study

Udai BanerjiCarla ML van HerpenCristina SauraFiona ThistiethwaiteSimon LordVictor MorenoIain R MacphersonValentina BoniChristian RolfoElisabeth GE de VriesSylvie RotteyJilt GeenenFerry EskensMarta Gil-MartinEllen C MommersNorbert P KoperPhilippe Aftimos

A1 Journal Article in LANCET ONCOLOGY

Very late xerostomia, dysphagia, and neck fibrosis after head and neck radiotherapy

Margot BaudeletLeen Van den SteenPeter TomassenKatrien BontePhilippe DeronWouter HuvenneSylvie RotteyWilfried De NeveNora SundahlGwen Van NuffelenFréderic Duprez

A1 Journal Article in HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

2018

A patient with acquired factor X deficiency and metastatic transitional cell carcinoma of the bladder : is there a link between metastasis and factor deficiency in solid tumors?

Timothy CammaertKarel DecaesteckerNora SundahlSylvie RotteyKatrien Devreese

A1 Journal Article in ANNALS OF HEMATOLOGY

A feasibility study on adaptive 18F-FDG-PET-guided radiotherapy for recurrent and second primary head and neck cancer in the previously irradiated territory

Julie SchattemanDirk Van GestelDieter BerwoutsWerner De GersemGeert De KerfWilfried De NeveBie De OstAna Maria Luiza OlteanuSylvie RotteyTom VercauterenIngeborg GoethalsFréderic Duprez

A1 Journal Article in STRAHLENTHERAPIE UND ONKOLOGIE

Congress highlights – ASCO 2018 special edition: Highlights in genitourinary cancers

Tijl VermassenSylvie Rottey

Congress highlights – ESMO 2018 special edition: Highlights in genitourinary cancers

Tijl VermassenSylvie Rottey

Evaluating the current place of radiotherapy as treatment option for patients with muscle invasive bladder cancer in Belgium

Valerie FonteyneElke RammantPiet OstYolande LievensBart De TroyerSylvie RotteyGert De MeerleerDaan De MaeseneerDirk De RidderKarel Decaestecker

A1 Journal Article in CLINICAL GENITOURINARY CANCER

Importance of choice of materials and methods in PD-L1 and TIL assessment in oropharyngeal squamous cell carcinoma

Astrid De MeulenaereTijl VermassenDavid CreytensSANDRINE ASPESLAGHPhilippe DeronFréderic DuprezSylvie RotteyJo Van DorpeLiesbeth Ferdinande

A1 Journal Article in HISTOPATHOLOGY

MRI in prostate cancer diagnosis, surgical or radiation treatment, focal therapy, active surveillance and follow-up

Chloë StandaertPieter De VisschereSylvie RotteySarah BuelensNora SundahlGeert Villeirs

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Metastatic burden in newly diagnosed hormone-naive metastatic prostate cancer : comparing definitions of CHAARTED and LATITUDE trial

Sarah BuelensFilip PoelaertBert DhondtValerie FonteynePieter De VisscherePiet OstSofie VerbekeGeert VilleirsKathia De ManSylvie RotteyKarel DecaesteckerNicolaas Lumen

A1 Journal Article in UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Neither creatinine- nor cystatin C-estimated glomerular filtration rate is optimal in oncology patients treated with targeted agents

Tijl VermassenKaren GeboesMarc De ManStéphanie LaurentElsie DecoeneNicolaas LumenJoris DelangheSylvie Rottey

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Pembrolizumab for the treatment of bladder cancer

Nora SundahlSylvie RotteyDaan De MaeseneerPiet Ost

A1 Journal Article in EXPERT REVIEW OF ANTICANCER THERAPY

Pharmacokinetic and pharmacodynamic relationships of copanlisib in patients with non-Hodgkin lymphoma and advanced solid tumors

F MorschhauserA AwadaJ-P MachielsGA SallesSylvie RotteyS RuleD CunninghamF PeyradeC FruchartH-T ArkenauI GenvresseL LiuC KneipC PenaJ GrevelJ ZhangG CisternasS ReschkeC Granvil

Sharp rise in the expenditures of targeted drugs in Ecuador : five-year (2010-2014) consumption of oncologic drugs in public and private hospitals

Carlos DuránMonique ElseviersRobert Vander SticheleSylvie RotteyThierry Christiaens

A2 Journal Article in JOURNAL OF PHARMACEUTICAL HEALTH SERVICES RESEARCH

2017

A phase I global trial targeting multiple solid and hematologic malignancies through a NKG2D receptor-based CAR-T immunotherapy

B VermaA AwadaP AftimosP LewalleN MeulemanJ-P MachielsG CatalaE VandennesteJ BrayerD SallmanS SahebjamTessa KerreSylvie RotteyK OdunsiES WangU SantanamC LonezDE GilhamF Lehmann

A phase I/II trial of fixed-dose stereotactic body radiotherapy with sequential or concurrent pembrolizumab in metastatic urothelial carcinoma : evaluation of safety and clinical and immunologic response

Nora SundahlKatrien De WolfSylvie RotteyKarel DecaesteckerDaan De MaeseneerAnnabel MeiresonEls GoetghebeurValerie FonteyneSofie VerbekePieter De VisschereDries ReyndersMireille Van GeleLieve BrochezPiet Ost

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

Abscopal effect in metastatic renal cell carcinoma

Mieke Van de WalleJan DemolLorenzo StaelensSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Androgen receptor gene copy number and protein expression in treatment-naïve prostate cancer

Filip PoelaertCandy KumpsNicolaas LumenStéphanie VerschuereLouis LibbrechtMarleen PraetSylvie RotteyTom ClaeysPiet OstKarel DecaesteckerGert De MeerleerCharles Van Praet

A1 Journal Article in UROLOGIA INTERNATIONALIS

Biomarkers in head and neck cancer : looking through and beyond the microscope

Astrid De MeulenaereSylvie RotteyLiesbeth Ferdinande

CD70 and PD-L1 in anaplastic thyroid cancer : promising targets for immunotherapy

Karen ZwaenepoelJulie JacobsAstrid De MeulenaereKaren SilenceEvelien SmitsVasiliki SiozopoulouEsther HaubenChristian RolfoSylvie RotteyPatrick Pauwels

A1 Journal Article in HISTOPATHOLOGY

Checkpoint inhibition : new treatment options in urologic cancer

Daan De MaeseneerBrant DelafontaineSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Combined high dose radiation and pazopanib in metastatic renal cell carcinoma : a phase I dose escalation trial

Katrien De WolfSylvie RotteyKarim VermaelenKarel DecaesteckerNora SundahlLizzy De LobelEls GoetghebeurGert De MeerleerNicolaas LumenValerie FonteyneDaan De MaeseneerPiet Ost

A1 Journal Article in RADIATION ONCOLOGY

Congress highlights – ESMO 2017 special edition: Highlights in genitourinary cancers

Tijl VermassenSylvie Rottey

Distant metastases in head and neck cancer

Fréderic DuprezDieter BerwoutsWilfried De NeveKatrien BonteTom BoterbergPhilippe DeronWouter HuvenneSylvie RotteyMarcus Mareel

A1 Journal Article in HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Evaluation of novel treatments in prostate cancer : concerning innovations in the field of minimal-invasive surgery, whole-pelvis radiotherapy and hormonal therapy with abiraterone acetate

Charles Van PraetNicolaas LumenSylvie Rottey

Highlights in genitourinary cancers from the 2017 ASCO Genitourinary Cancers Symposium

Tijl VermassenSylvie Rottey

Editorial material

How far to investigate presumed psychosomatic symptoms : lessons from a particular case…

Marie-Angélique De ScheerderSylvie RotteyAn MarimanMarleen PraetDirk Vogelaers

A1 Journal Article in ACTA CLINICA BELGICA

Impact of haptoglobine polymorphism on survival of renal cell carcinoma patients

Tijl VermassenNicolaas LumenJoris DelangheSylvie Rottey

Metastatic burden in newly diagnosed hormone-naive metastatic prostate cancer : comparing the definitions of CHAARTED and LATITUDE trial

Sarah BuelensKarel DecaesteckerValerie FonteynePiet OstSofie VerbekeGeert VilleirsSylvie RotteyNicolaas Lumen

Phase I dose-escalation study of the anti-CD70 antibody ARGX-110 in advanced malignancies

Philippe AftimosChristian RolfoSylvie RotteyFritz OffnerDominique BronMarie MaerevoetJean-Charles SoriaMahan MoshirTorsten DreierLuc Van RompaeyJean-Marie MichotKaren SilenceAnna HultbergDomenica GandiniHans de HaardVincent RibragMarc PeetersAlain ThibaultNicolas LeupinAhmad Awada

A1 Journal Article in CLINICAL CANCER RESEARCH

Phenotyping of the immune infiltrate in oropharyngeal squamous cell carcinoma : focus on materials and methods

Astrid De MeulenaereTijl VermassenSylvie RotteyLiesbeth Ferdinande

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy

Julie JacobsVanessa DeschoolmeesterChristian RolfoKaren ZwaenepoelJolien Van den BosscheChristophe DebenKaren SilenceHans de HaardChristophe HermansSylvie RotteyChristel VangestelFilip LardonEvelien SmitsPatrick Pauwels

A1 Journal Article in ONCOTARGET

Prognostic markers in oropharyngeal squamous cell carcinoma : focus on CD70 and tumour infiltrating lymphocytes

Astrid De MeulenaereTijl VermassenSandrine AspeslaghKaren ZwaenepoelPhilippe DeronFréderic DuprezSylvie RotteyLiesbeth Ferdinande

A1 Journal Article in PATHOLOGY

Release of urinary extracellular vesicles in prostate cancer is associated with altered urinary N-glycosylation profile

Tijl VermassenKatharina D'HerdeDominique JacobusCharles Van PraetFilip PoelaertNicolaas LumenNico CallewaertKarel DecaesteckerGeert VilleirsPiet HoebekeSimon Van BelleSylvie RotteyJoris Delanghe

A1 Journal Article in JOURNAL OF CLINICAL PATHOLOGY

TILs in head and neck cancer : ready for clinical implementation and why (not)?

Astrid De MeulenaereTijl VermassenSANDRINE ASPESLAGHKatrien VandecasteeleSylvie RotteyLiesbeth Ferdinande

A2 Journal Article in HEAD & NECK PATHOLOGY

The independent oncological role for cytoreductive nephrectomy in metastatic renal cell carcinoma : prognostic features in the era of targeted therapies

Tom ClaeysNicolaas LumenCandy KumpsMarleen PraetGert De MeerleerSylvie RotteyPiet OstPieter De VisschereGeert VilleirsValerie FonteyneKarel Decaestecker

A1 Journal Article in UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Tumor PD-L1 status and CD8+ tumor-infiltrating T cells : markers of improved prognosis in oropharyngeal cancer

Astrid De MeulenaereTijl VermassenSANDRINE ASPESLAGHPhilippe DeronFréderic DuprezDebby LaukensJo Van DorpeLiesbeth FerdinandeSylvie Rottey

A1 Journal Article in ONCOTARGET

Turning the tide : clinical utility of PD-L1 expression in squamous cell carcinoma of the head and neck

Astrid De MeulenaereTijl VermassenSANDRINE ASPESLAGHWouter HuvenneJo Van DorpeLiesbeth FerdinandeSylvie Rottey

A1 Journal Article in ORAL ONCOLOGY

Which factors predict overall survival in patients with metastatic castration-resistant prostate cancer treated with abiraterone acetate post-docetaxel?

Charles Van PraetSylvie RotteyFransien Van HendeGino PelgrimsWim DemeyFilip Van AelstWim WynendaeleThierry GilPeter SchattemanBertrand FilleulDenis SchallierJean-Pascal MachielsDirk SchrijversEls EveraertLionel D'HondtPatrick WerbrouckJoanna VermeijJeroen MebisMarylene ClausseMarika RasschaertJoanna Van ErpsJolanda VerheezenJan Van HaverbekeJean-Charles GoeminneNicolaas Lumen

A1 Journal Article in CLINICAL GENITOURINARY CANCER

2016

A phase I pharmacokinetic and safety study of cabazitaxel in adult cancer patients with normal and impaired renal function

Analía AzaroJordi RodónJean-Pascal MachielsSylvie RotteySilvia DamianRichard BairdJavier Garcia-CorbachoRon HJ MathijssenPierre-François ClotClaudine WackLiji ShenMaja JA de Jonge

A1 Journal Article in CANCER CHEMOTHERAPY AND PHARMACOLOGY

A phase I study in T cell lymphoma patients treated with anti-CD70 simple antibody (TM) ARGX-110

JM MichotM MaerevoetP AftimosSylvie RotteyC RolfoFritz OffnerL Van RompaeyM MoshirH de HaardK SilenceM BagotP PauwelsK ZwaenepoelA AwadaD BronV Ribrag

Abiraterone acetate post-docetaxel for metastatic castration-resistant prostate cancer in the Belgian compassionate use program

Charles Van PraetSylvie RotteyFransien Van HendeGino PelgrimsWim DemeyFilip Van AelstWim WynendaeleThierry GilPeter SchattemanBertrand FilleulDennis SchallierJean-Pascal MachielsDirk SchrijversEls EveraertLionel D'HondtPatrick WerbrouckJoanna VermeijJeroen MebisMarylene ClausseMarika RasschaertJoanna Van ErpsJolanda VerheezenJan Van HaverbekeJean-Charles GoeminneNicolaas Lumen

A1 Journal Article in UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

CD70 Expression and its correlation with clinicopathological variables in squamous cell carcinoma of the head and neck

Astrid De MeulenaereTijl VermassenSandrine AspeslaghKaren ZwaenepoelPhilippe DeronFréderic DuprezLiesbeth FerdinandeSylvie Rottey

A1 Journal Article in PATHOBIOLOGY

Clinical response observed in a phase I study in T cell lymphoma patients treated with anti-CD70 SIMPLE antibody ARGX-110

Jean-Marie MichotMarie MaerevoetPhilippe Georges AftimosSylvie RotteyChristian Diego RolfoFritz OffnerLuc Van RompaeyMahan MoshirHans de HaardKaren SilencePatrick PauwelsKaren ZwaenepoelAhmad AwadaDominique BronVincent Ribrag

Congress highlights – ASCO 2016 special edition: Highlights in genitourinary cancers

Tijl VermassenSylvie Rottey

Congress highlights – ESMO 2016 special edition: Highlights in genitourinary cancers

Tijl VermassenSylvie Rottey

Effect of itraconazole and rifampin on the pharmacokinetics of olaparib in patients with advanced solid tumors : results of two phase I open-label studies

Luc DirixHelen SwaislandHenk MW VerheulSylvie RotteyKarin LeunenGuy JerusalemChristian RolfoDorte NielsenL Rhoda MolifeRebecca KristeleitJudith de Vos-GeelenMorten Mau-SørensenPatricia SoetekouwCarla van HerpenAnitra FieldingKaren SoWendy BannisterRuth Plummer

A1 Journal Article in CLINICAL THERAPEUTICS

Glycosylation of urinary prostate proteins and its potential diagnostic applications

Tijl VermassenSylvie RotteyJoris Delanghe

Phase I study of mTORC1/2 inhibitor BI 860585 as single agent or with exemestane or paclitaxel in patients with advanced solid tumors

Filippo G De BraudJean-Pascal H MachielsMarcello TiseoSylvie RotteyMatteo DucaMarie LaruelleStefania SalvagniLore LapeireLaura ManfredaCeline VeauDaniela FischerMahmoud Ould-Kaci

Phase I study of ribociclib plus cetuximab in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

E SerontS SchmitzSylvie RotteyS HenryC LonchayG van CaloenA GilainJ-P Machiels

Phase II study of dual phosphoinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor BEZ235 in patients with locally advanced or metastatic transitional cell carcinoma

Emmanuel SerontSylvie RotteyBertrand FilleulPhilippe GlorieuxJean-Charles GoeminneVincent VerschaeveJean-Marie VandenbulckeBrieuc SautoisPetra BoegnerAline GillainAline van MaanenJean-Pascal Machiels

A1 Journal Article in BJU INTERNATIONAL

Randomized phase II study of cabazitaxel versus methotrexate in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck previously treated with platinum-based therapy

Jean-Pascal Henry MachielsAline Van MaanenJean-Marie VandenbulckeBertrand FilleulEmmanuel SerontStéphanie HenryLionel D'HondtChristophe LonchayStéphane HolbrechtsPetra BoegnerDany BroheeDidier DequanterIngrid LouviauxBrieuc SautoisNicolas WhenhamGuy BerchemBrigitte VanderschuerenChristel FontaineSandra SchmitzAline GillainJoelle SchoonjansSylvie Rottey

A1 Journal Article in ONCOLOGIST

Therapeutic approaches in clear cell and non-clear cell renal cell carcinoma

Tijl VermassenAstrid De MeulenaereM. Van de WalleSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Virussen in de behandeling van kanker : oncolytische virotherapie

Brant DelafontaineGriet Van LanckerLucas Van BortelSylvie Rottey

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2015

A phase I study of volasertib combined with afatinib, in advanced solid tumors

Jean-Pascal MachielsMarc PeetersCatherine HerremansVeerle SurmontPol SpecenierMarina De SmetKorinna PilzNatalja StrelkowaDan LiuSylvie Rottey

A1 Journal Article in CANCER CHEMOTHERAPY AND PHARMACOLOGY

Battling resistance mechanisms in antihormonal prostate cancer treatment: novel agents and combinations

Daan Joost De MaeseneerCharles Van PraetNicolaas LumenSylvie Rottey

A1 Journal Article in UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Congress highlights: ASCO 2015 special edition: highlights in genitourinary cancers from the 2015 ASCO annual meeting

Tijl VermassenSylvie Rottey

Editorial material

Congress highlights: ECCO-ESMO 2015 special edition: highlights in genitourinary cancers from the 18th ECCO – 40th ESMO European cancer congress

Tijl VermassenSylvie Rottey

Editorial material

Diagnostic accuracy of urinary prostate protein glycosylation profiling in prostatitis diagnosis

Tijl VermassenCharles Van PraetFilip PoelaertNicolaas LumenKarel DecaesteckerPiet HoebekeSimon Van BelleSylvie RotteyJoris Delanghe

A1 Journal Article in BIOCHEMIA MEDICA

Evaluation of abiraterone acetate post-docetaxel in the Belgian compassionate use program

Sylvie RotteyCharles Van PraetFransien Van HendeGino PelgrimsWim DemeyFilip Van AelstWim WynendaeleThierry GilPeter SchattemanBertrand FilleulDennis SchallierJean-Pascal MachielsDirk SchrijversEls EveraertLionel D'HondtPatrick WerbrouckJoanna VermeijJeroen MebisMarylene ClausseMarika RasschaertJoanna Van ErpsJolanda VerheezenJan Van HaverbekeJean-Charles GoeminneNicolaas Lumen

Evaluation of the effect of cytoreductive nephrectomy on the course of metastatic renal cell carcinoma: a single centre study

Tom ClaeysNicolaas LumenGilles ThuysbaertMarleen PraetGert De MeerleerSylvie RotteyPiet OstPieter De VisschereGeert VilleirsValérie FonteyneKarel Decaestecker

G-8 indicates overall and quality-adjusted survival in older head and neck cancer patients treated with curative radiochemotherapy

Lies PottelMichelle LyckeTom BoterbergHans PottelLaurence GoethalsFréderic DuprezSylvie RotteyYolande LievensNele Van Den NoortgateKurt GeldhofVéronique BuyseKhalil Kargar-SamaniVéronique GhekierePhilip Debruyne

A1 Journal Article in BMC CANCER

Immunohistochemical analysis of CD70 expression in 95 cases of squamous cell carcinoma of the head and neck: correlation with clinicopathological variables and identification of a novel therapeutic target

Astrid De MeulenaereTijl VermassenS AspeslaghPhilippe DeronFréderic DuprezK SilenceJ JacobsK ZwaenepoelP PauwelsSylvie RotteyLiesbeth Ferdinande

Necrotizing myopathy as a paraneoplastic syndrome associated with renal cell carcinoma

Eline NaertJan De BleeckerNicolaas LumenSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Oncogenetic testing, diagnosis and follow-up in Birt-Hogg-Dubé syndrome, familial atypical multiple mole melanoma syndrome and neurofibromatosis 1 and 2

Jo RobaysSabine StordeurFrank HulstaertJean-François BaurainLieve BrochezTeofila CaplanusiKathleen ClaesEric LegiusSylvie RotteyDirk SchrijversDaphné 't Kint de RoodenbekeUrielle UllmanTom Van MaerkenBruce Poppe

Prolonged survival in a nasopharyngeal carcinoma (NPC) patient with metastatic disease : a case report

Astrid De MeulenaerePhilippe DeronFréderic DuprezLiesbeth FerdinandeLuc VerbekeM De VuystSylvie Rottey

A2 Journal Article in AUSTIN JOURNAL OF OTOLARYNGOLOGY

REACT expanded-access program in patients with metastatic renal cell carcinoma : real-world data from a European subanalysis

S BracardaSylvie RotteyA BahlC EichelbergB MelladoL MangelA CattaneoA PanneerselvamV Grunwald

A1 Journal Article in FUTURE ONCOLOGY

Second Belgian multidisciplinary meeting on urological cancers held in Brussels, March 28th, 2015

Tijl VermassenPieter De VisschereGeert VilleirsD SchrijversSylvie Rottey

Editorial material

Urinary prostate protein glycosylation profiling as a diagnostic biomarker for prostate cancer

Tijl VermassenCharles Van PraetNicolaas LumenKarel DecaesteckerDieter VanderschaegheNico CallewaertGeert VilleirsPiet HoebekeSimon Van BelleSylvie RotteyJoris Delanghe

A1 Journal Article in PROSTATE

2014

A first-in-class, first-in-human phase I study of enadenotucirev, an oncolytic Ad11/Ad3 chimeric group B adenovirus, administered intravenously in patients with metastatic epithelial tumors.

Emiliano CalvoMarta Gil-MartinJean-Pascal MachielsSylvie RotteyAntonio CubilloRamon SalazarFeby Ingriani MardjuadiKaren GeboesChristopher EllisJohn William BeadleChristine Blanc

Agreement of Gleason score on prostate biopsy and radical prostatectomy specimen: is there improvement with increased number of biopsy cylinders and the 2005 revised Gleason scoring?

Charles Van PraetLouis LibbrechtFrederik D'HontKarel DecaesteckerValérie FonteyneStephanie VERSCHUERESylvie RotteyMarleen PraetPieter De VisschereNicolaas Lumen

A1 Journal Article in CLINICAL GENITOURINARY CANCER

An open-label study to investigate the cardiac safety profile of cabazitaxel in patients with advanced solid tumors

Pierre Maison-BlancheShaker DakhilAri BaronSylvie RotteyFred MillardGedske DaugaardJean-Pascal MachielsWilliam ConkrightSunil SharmaPatricia MMB SoetekouwJeffrey YachninLisa SengelovPeter Van VeldhuizenSanjiv S AgarwalaDorothee SemiondMustapha ChadjaaLiji ShenJames L Wade

A1 Journal Article in CANCER CHEMOTHERAPY AND PHARMACOLOGY

Capillary electrophoresis of urinary prostate glycoproteins assists in the diagnosis of prostate cancer

Tijl VermassenCharles Van PraetDieter VanderschaegheThomas MaenhoutNicolaas LumenNico CallewaertPiet HoebekeSimon Van BelleSylvie RotteyJoris Delanghe

A1 Journal Article in ELECTROPHORESIS

Chromosome X polysomy is associated with increased androgen receptor expression in epithelial cells and reduced expression in stromal cells in treatment-naive prostate cancer

Charles Van PraetFilip PoelaertStephanie VERSCHUERELouis LibbrechtMarleen PraetSylvie RotteySimon Van BelleKarel DecaesteckerTom ClaeysNicolaas Lumen

Congress highlights: ESMO 2014 special edition: highlights in genitourinary cancer

Tijl VermassenSylvie Rottey

Editorial material

Congress highlights: first Belgian multidisciplinary meeting on urological cancers held in Brussels, March 29th 2014

Tijl VermassenJan Martijn KerstBertrand TombalSylvie Rottey

Editorial material

Contemporary minimally-invasive extended pelvic lymph node dissection for prostate cancer before curative radiotherapy: prospective standardized analysis of complications

Charles Van PraetKarel DecaesteckerValérie FonteynePiet OstPieter De VisschereStephanie VERSCHUERESylvie RotteyNicolaas Lumen

A1 Journal Article in INTERNATIONAL JOURNAL OF UROLOGY

Echium oil is not protective against weight loss in head and neck cancer patients undergoing curative radio(chemo)therapy: a randomised-controlled trial

Lies PottelMichelle LyckeTom BoterbergHans PottelLaurence GoethalsFréderic DuprezAlex MaesStefan GoemaereSylvie RotteyImogen FoubertPhilip R Debruyne

A1 Journal Article in BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE

Possible use of urinary prostate proteins glycosylation profile as a diagnostic biomarker for prostate cancer

Tijl VermassenNicolaas LumenCharles Van PraetDieter VanderschaegheNico CallewaertPiet HoebekeSimon Van BelleJoris DelangheSylvie Rottey

Prospective non-interventional multicentre observational trial of first-line anti-cancer treatment in patients with metastatic renal cell cancer in Belgium

NATASHA CORNELISTijl VermassenD SchallierJ-P MachielsT GilPR DebruyneR D'hondtA BolsD SchrijversJ MebisNicolaas LumenSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Serial comprehensive geriatric assessment in elderly head and neck cancer patients undergoing curative radiotherapy identifies evolution of multidimensional health problems and is indicative of quality of life

Lies PottelMichelle LyckeTom BoterbergHans PottelLaurence GoethalsFréderic DuprezNele Van Den NoortgateWilfried De NeveSylvie RotteyKurt GeldhofVeronique BuysseK Kargar-SamaniVeronique GhekierePhilip R Debruyne

A1 Journal Article in EUROPEAN JOURNAL OF CANCER CARE

Sunitinib for metastatic renal cell cancer patients: observational study highlighting the risk of important drug-drug interactions

VIBEKE KRUSEAnnemie SomersLucas Van BortelANNELEEN DE BOTHSimon Van BelleSylvie Rottey

A1 Journal Article in JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Third Belgian multidisciplinary meeting on urological cancers

Tijl VermassenRonald De WitRoland Van VelthovenSimone AlbisinniNieves Martinez ChanzaFouad Youssef AounEmmanuel SerontSylvie Rottey

2013

A phase Ib, open-label study to assess the safety of continuous oral treatment with afatinib in combination with two chemotherapy regimens: cisplatin plus paclitaxel and cisplatin plus 5-fluorouracil, in patients with advanced solid tumors

JB VermorkenSylvie RotteyE EhrnroothK PellingA LahogueS WindJ-P Machiels

A1 Journal Article in ANNALS OF ONCOLOGY

Attacking the androgen receptor pathway in prostate cancer

Charles Van PraetDaan De MaeseneerNicolaas LumenSylvie Rottey

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): an open-label phase 3 randomised trial

Jan B VermorkenJan Stoelmacher-WilliamsIrina DavidenkoLisa LicitraEric WinquistCristian VillanuevaPaolo FoaSylvie RotteyKrzysztof SkladowskiMakoto TaharaVasant R PaiSandrine FaivreCesar R BlajmanArlene A ForastiereBrian N SteinKelly S OlinerZhiying PanBruce A Bach

A1 Journal Article in LANCET ONCOLOGY

Prostate proteins glycosylation profile and its potential as a diagnostic biomarker for prostate cancer

Tijl VermassenNicolaas LumenCharles Van PraetDieter VanderschaegheNico CallewaertPiet HoebekeSimon Van BelleSylvie RotteyJoris Delanghe

Retrospective analysis of metastatic renal cell cancer patients treated with sunitinib and the role of possible interactions

VIBEKE KRUSEA De BothN BeckLucas Van BortelSimon Van BelleSylvie Rottey

Serial Comprehensive Geriatric Assessment in elderly head and neck cancer patients undergoing curative radiotherapy identifies evolution of multidimensional health problems and is indicative of quality of life

Lies PottelMichelle LyckeTom BoterbergHans PottelLaurence GoethalsFréderic DuprezNele Van Den NoortgateWilfried De NeveSylvie RotteyKurt GeldhofVéronique BuyseKhalil Kargar-SamaniVéronique GhekierePhilip R Debruyne

2012

Androgen receptor gene amplification in primary prostate cancer patients

Charles Van PraetLouis LibbrechtSylvie RotteyMarleen PraetSimon Van BelleNicolaas Lumen

Blaasconserverende behandelingen voor invasieve blaaskanker: een te weinig gebruikte mogelijkheid

Karel DecaesteckerGert De MeerleerSylvie RotteyNicolaas LumenValérie FonteyneWillem Oosterlinck

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Compliance with sunitinib treatment in patients with renal cell cancer

ANNELEEN DE BOTHVIBEKE KRUSEElise De CoeneNELE CLOTTENSAnnemie SomersSimon Van BelleLucas Van BortelSylvie Rottey

De plaats van cetuximab in de behandeling van hoofd- en halstumoren

Lore LapeirePhilippe DeronFréderic DuprezSylvie Rottey

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Determination of an adequate screening tool for identification of vulnerable elderly head and neck cancer patients treated with radio(chemo)therapy

Lies PottelTom BoterbergHans PottelLaurence GoethalsNele Van Den NoortgateFréderic DuprezWilfried De NeveSylvie RotteyKurt GeldhofKoen Van EygenKhalil Kargar-SamaniVéronique GhekiereFrank CornelisSupriya MohilePhilip R Debruyne

A1 Journal Article in JOURNAL OF GERIATRIC ONCOLOGY

Experience with Lexicomp® Online Drug Database for medication review and drug-drug interaction analysis within a comprehensive geriatric assessment in elderly cancer patients

Lies PottelMichelle LyckeTom BoterbergLore KetelaarsHans PottelLaurence GoethalsNele Van Den NoortgateFréderic DuprezWilfried De NeveSylvie RotteyKurt GeldhofKoen Van EygenKhalil Kargar-SamaniVéronique GhekiereAnne VerhaeghePhilip Debruyne

A2 Journal Article in JOURNAL OF ANALYTICAL ONCOLOGY

Experience with Lexicomp® online drug database for medication review and drug-drug interaction analysis within comprehensive geriatric assessment in elderly cancer patients

Michelle LyckeLies PottelTom BoterbergHans PottelLaurence GoethalsNele Van Den NoortgateFréderic DuprezWilfried De NeveSylvie RotteyKurt GeldhofKhalil Kargar-SamaniVéronique GhekiereAnne VerhaeghePhilip R Debruyne

Glycosylation of prostate specific antigen and its potential diagnostic applications

Tijl VermassenMarijn SpeeckaertNicolaas LumenSylvie RotteyJoris Delanghe

A1 Journal Article in CLINICA CHIMICA ACTA

International, expanded-access programme of everolimus in patients with metastatic renal cell carcinoma who progressed after prior vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy: sub-analysis of European patients

S BracardaSylvie RotteyA BahlC EichelbergB MelladoL MangelJ MardiakI BouzaklasA PanneerselvamV Grunwald

Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers

E SerontSylvie RotteyB SautoisJ KergerLA D'HondtV VerschaeveJ-L CanonC DopchieJM VandenbulckeN WhenhamJC GoeminneM ClausseD VerhoevenP GlorieuxS BrandersP DupontJ SchoonjansO FeronJ-P Machiels

A1 Journal Article in ANNALS OF ONCOLOGY

Serial comprehensive geriatric evaluation in elderly head and neck cancer patients undergoing radiotherapy

PR DebruyneM LyckeTom BoterbergH PottelL GoethalsNele Van Den NoortgateFréderic DuprezSylvie RotteyK Kargar-SamaniL Pottel

Serial comprehensive geriatric evaluation in elderly head and neck cancer patients undergoing radiotherapy

Philip R DebruyneMichelle LyckeTom BoterbergHans PottelLaurence GoethalsNele Van Den NoortgateFréderic DuprezSylvie RotteyKhalil Kargar-SamaniLies Pottel

Serial comprehensive geriatric evaluation in older head and neck cancer patients undergoing radiotherapy

Lies PottelMichelle LyckeTom BoterbergHans PottelLaurence GoethalsLore KetelaarsNele Van Den NoortgateFréderic DuprezWilfried De NeveSylvie RotteyKurt GeldhofKoen Van EygenKhalil Kargar-SamaniVéronique GhekiereSupriya MohilePhilip R Debruyne

2011

'Doe-het-zelf chemotherapie advies' : gevaarlijke ontwikkelingen via het worldwide web

Karen GeboesSylvie RotteyStéphanie LaurentJohan VandenbrouckeMarc Peeters

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

A phase Ib open-label study to assess continuous oral treatment with afatinib (BIBW 2992) in combination with two chemotherapy regimens: cisplatin plus paclitaxel, and cisplatin plus 5-fluorouracil in patients, with advanced solid tumours

J VermorkenSylvie RotteyE EhrnroothK PellingA LahogueJ Machiels

Angiogenesis-related cytokines as potential predictive biomarkers in a phase II trial evaluating everolimus efficacy in locally advanced or metastatic transitional carcinoma cell

E SerontSylvie RotteyB SautoisL DhondtJ-L CanonJ-M VandenbulckeN WhenhamJ-C GoeminneO FeronJ-P Machiels

Cardiovascular toxicity of cancer treatment

MATTHIEU COMBESSylvie RotteyTine De Backer

A1 Journal Article in ACTA CLINICA BELGICA

Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study

L LicitraR MesiaF RiveraÉ RemenárR HittJ ErfánSylvie RotteyA KaweckiD ZabolotnyyM BenassoS StörkelS SengerC StrohJB Vermorken

A1 Journal Article in ANNALS OF ONCOLOGY

High dose chemotherapy and stem cell rescue for metastatic germ cell tumours: long term results from a single institution

VIBEKE KRUSELucien NoensNicolaas LumenPiet HoebekeSimon Van BelleSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Metabolic tumour volume : prognostic value in locally advanced squamous cell carcinoma of the head and neck

Philippe DeronKoen MertensIngeborg GoethalsSylvie RotteyFréderic DuprezWilfried De NeveHubert VermeerschChristophe Van De Wiele

A1 Journal Article in NUKLEARMEDIZIN-NUCLEAR MEDICINE

Modern treatment for nasopharyngeal carcinoma : current status and prospects

Sylvie RotteyIndira MadaniPhilippe DeronSimon Van Belle

A1 Journal Article in CURRENT OPINION IN ONCOLOGY

Nephrotoxicity of anticancer drugs: an underestimated problem?

Norbert LameireVIBEKE KRUSESylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

PARP inhibitors in oncology: a new synthetic lethal approach to cancer therapy

VIBEKE KRUSESylvie RotteyOle De BackerSimon Van BelleVeronique CocquytHannelore Denys

A1 Journal Article in ACTA CLINICA BELGICA

2010

18-Fluorodeoxyglucose positron emission tomography as a tool for response prediction in solid tumours

Daan De MaeseneerBieke LambertVeerle SurmontKaren GeboesSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

Cardiac toxicity of trastuzumab : experience at the Ghent University Hospital, Belgium

CAROLINE LAMOTSylvie RotteyTine De BackerLucas Van BortelHugo RobaysSimon Van BelleHannelore DenysVeronique Cocquyt

A1 Journal Article in ACTA CLINICA BELGICA

Efficacy and Safety of Pazopanib in Patients With Metastatic Renal Cell Carcinoma

TE HutsonID DavisJPH MachielsPL De SouzaSylvie RotteyBF HongRJ EpsteinKL BakerL McCannT CroftsL PanditeRA Figlin

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Quality of life of patients receiving platinum-based chemotherapy plus cetuximab first line for recurrent and/or metastatic squamous cell carcinoma of the head and neck

R MesíaF RiveraA KaweckiSylvie RotteyR HittH KienzerD CupissolD De RaucourtM BenassoP KoralewskiJP DelordC BokemeyerD CurranA GrossJB Vermorken

A1 Journal Article in ANNALS OF ONCOLOGY

Targeted therapy for metastatic renal cell cancer

CAROLINE VERBAEYSPiet HoebekeSimon Van BelleSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

2009

A RARE INFECTIOUS COMPLICATION AFTER ENDOSCOPIC ULTRASOUND GUIDED FINE NEEDLE ASPIRATION IN AN ONCOLOGICAL PATIENT AND REVIEW OF THE LITERATURE

FRANK VAN FRAEYENHOVECAROLINE LAMOTDirk VogelaersSimon Van BelleErcan CesmeliSylvie Rottey

A1 Journal Article in Acta Clinica Belgica

Complicaties van oncologische therapie thuis opvangen

Sylvie RotteyLucas Van BortelSimon Van Belle

A2 Journal Article in Tijdschrift voor Geneeskunde

Influence of chemotherapy on the biodistribution of [99mTc]hydrazinonicotinamide annexin V in cancer patients

Sylvie RotteyBIEKE VAN DEN BOSSCHEG SlegersSimon Van BelleChristophe Van De Wiele

A1 Journal Article in QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Mitoxantronchemotherapie voor de behandeling van multiple sclerose

Lore LapeireJan DebruyneSylvie Rottey

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Trombotische microangiopathie als eerste teken van gemetastaseerd borstcarcinoom

Wouter De CorteSylvie RotteyPieter DepuydtJOKE NOLLETJ. PhillipéDominique Benoit

A2 Journal Article in Tijdschrift voor Geneeskunde

Verwikkelingen van oncologische therapie thuis opvangen

Sylvie RotteyLucas Van BortelSimon Van Belle

A2 Journal Article in Tijdschrift voor geneeskunde

2008

F-18 fluorodeoxyglucose PET/CT scanning in the diagnostic work-up of a primary pericardial mesothelioma - A case report

Piet OstSylvie RotteyPeter SmeetsTom BoterbergBarbara StragierIngeborg Goethals

A1 Journal Article in Journal of Thoracic Imaging

OSTEOSARCOMA WITH EXTENSIVE CALCIFIED PLEURAL METASTASES AT DIAGNOSIS

NATACHA VERBEKEKoenraad VerstraeteGwen SysRamses ForsythD. KluyskensHannelore DenysDirk UyttendaeleSylvie Rottey

A1 Journal Article in Acta Clinica Belgica

Platinum-based chemotherapy plus cetuximab in head and neck cancer

Jan VermorkenRicard MesiaFernando RiveraEva RemenarAndrzej KaweckiSylvie RotteyJozsef ErfanDmytro ZabolotnyyHeinz-Roland KienzerDidier CupissolFrederic PeyradeMarco BenassoIhor VynnychenkoDominique De RaucourtCarsten BokemeyerArmin SchuelerNadia AmellalRicardo Hitt

A1 Journal Article in New England Journal of Medicine

2007

(99m)Tc-HYNIC Annexin-V imaging of tumors and its relationship to response to radiotherapy and/or chemotherapy

Sylvie RotteyD LOOSELuc VakaetC LAHORTEHubert VermeerschSimon Van BelleChristophe Van De Wiele

A2 Journal Article in Q J Nucl Med Mol Imaging

A Belgian registry of interleukin-2 administration for treatment of metastatic renal cell cancer and confrontation with literature data

Inneke BambustF. Van AelstE. JoosensD. SchallierH. KalantariR. PaulusVincent RenardM. ClausseL. DuckS. LuceP. PierreSimon Van BelleSylvie Rottey

A1 Journal Article in ACTA CLINICA BELGICA

One-stage penectomy and phalloplasty for epithelioid sarcoma of the penis in an adolescent

Piet HoebekeSylvie RotteyNathalie Van HeddeghemGeert VilleirsPatrick PauwelsWILLY SCHRAUWENPeter CeulemansStan Monstrey

A1 Journal Article in EUROPEAN UROLOGY

One-stage penectomy and phalloplasty for epithelioid sarcoma of the penis in an adolescent, part 2

Piet HoebekeSylvie RotteyNathalie Van HeddeghemGeert VilleirsPASCALE PAUWELSWILLY SCHRAUWENPeter CeulemansStan Monstrey

A1 Journal Article in EUROPEAN UROLOGY

Radiolabelled chemotherapeutics

Sylvie RotteyA SIGNOREChristophe Van De Wiele

A1 Journal Article in QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Tc-99m-HYNIC Annexin-V imaging of tumors and its relationship to response to radiotherapy and/or chemotherapy

Sylvie RotteyDavid LooseLuc VakaetC LAHORTEHubert VermeerschSimon Van BelleChristophe Van De Wiele

A1 Journal Article in QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

2006

Evaluation of metastatic lymph nodes in head and neck cancer: A comparative study between palpation, ultrasonography, ultrasound-guided fine needle aspiration cytology and computed tomography

Sylvie RotteyMirko PetrovicWouter BautersKris MervillieELS VANHERREWEGHEKatrien BonteSimon Van BelleHubert Vermeersch

A1 Journal Article in ACTA CLINICA BELGICA

Sequential Tc-99m-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy

Sylvie RotteyGuido SlegersSimon Van BelleIngeborg GoethalsChristophe Van De Wiele

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

2004

Intraobserver, interobserver, and day-to-day reproducibility of quantitative Tc-99m-HYNIC annexin-V imaging in head and neck carcinoma

Hubert VermeerschHamphrey HamSylvie RotteyC LAHORTEF CORSETTIRudi DierckxN STEINMETZChristophe Van De Wiele

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

2003

99(m)Tc sestamibi and Tc-99m tetrofosmin scintigraphy for predicting resistance to chemotherapy: a critical review of clinical data

Christophe Van De WieleSylvie RotteyIngeborg GoethalsJ BUSCOMBESimon Van BelleFilip De VosRudi Dierckx

Editorial material

99mTc sestamibi and 99mTc tetrofosmin scintigraphy for predicting resistance to chemotherapy: a critical review of clinical data

Christophe Van De WieleSylvie RotteyIngeborg GoethalsJ BUSCOMBESimon Van BelleF DE VOSRudi Dierckx

A2 Journal Article in NUCLEAR MEDICINE COMMUNICATIONS

How does biotherapy compare with chemotherapy for cancer?

Simon Van BelleSylvie RotteyVINCENT RENARD

A2 Journal Article in Enhancer

2000

Progression of renal failure in patients with compromised renal function is not always present : evaluation of underlying disease

Sylvie RotteyRaymond VanholderG De SchoenmakereNorbert Lameire

A1 Journal Article in CLINICAL NEPHROLOGY