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Researcher
Sylvie Lierman
Profile
Projects
Publications
Activities
Awards & Distinctions
70
Results
2021
Low feasibility of in vitro matured oocytes originating from cumulus complexes found during ovarian tissue preparation at the moment of gender confirmation surgery and during testosterone treatment for fertility preservation in transgender men
Sylvie Lierman
Annelies Tolpe
Ilse De Croo
Stefanie De Gheselle
Justine Defreyne
Machteld Baetens
Annelies Dheedene
Roos Colman
Björn Menten
Guy T'Sjoen
et al.
A1
Journal Article
in
FERTILITY AND STERILITY
2021
Passive slow freezing is an efficacious and cost-effective alternative to controlled slow freezing for ovarian tissue cryopreservation
Sylvie Lierman
A. Bus
S. Andries
E. Trias
P. E. J. Bols
Kelly Tilleman
A1
Journal Article
in
CRYOBIOLOGY
2021
2020
In vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Petra De Sutter
C3
Conference
2020
In-vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2020
Swim-up as a strategy for isolation of spermatozoa without viral incorporation in men with chronic hepatitis B : a pilot study
Thomas Condijts
Liesl Bourdeaud'huy
Kelly Tilleman
Sylvie Lierman
Chantal Dewinter
Elizaveta Padalko
A1
Journal Article
in
ANDROLOGIA
2020
Treating transgender people
Kelly Tilleman
Chloë De Roo
Sylvie Lierman
Petra De Sutter
Bookchapter
in
Textbook of assisted reproduction
2020
2019
Endometrial stromal cell proteome mapping in repeated implantation failure and recurrent pregnancy loss cases and fertile women
Lien Dhaenens
Sylvie Lierman
Laura De Clerck
Elisabeth Govaert
Dieter Deforce
Kelly Tilleman
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2019
2018
Ovarian tissue cryopreservation in female-to-male transgender persons : insights in ovarian histology and physiology after prolonged androgen treatment
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Karen Peynshaert
Kevin Braeckmans
Mirte Caanen
Cornelis Lambalk
Steven Weyers
Petra De Sutter
C3
Conference
2018
Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes
Yuechao Lu
Minerva Ferrer Buitrago
Mina Popovic
Jitesh Neupane
Winnok De Vos
Sylvie Lierman
Etienne Van den Abbeel
Margot Van der Jeught
Dimitra Nikiforaki
Petra De Sutter
et al.
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2018
Strontium fails to induce Ca2+ release and activation in human oocytes despite the presence of functional TRPV3 channels
Y Lu
R Reddy
Minerva Ferrer Buitrago
Margot Van der Jeught
Jitesh Neupane
Winnok De Vos
Etienne Van den Abbeel
Sylvie Lierman
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION OPEN
2018
Transcriptional landscape changes during human embryonic stem cell derivation
Sharat Warrier
Jasin Taelman
Laurentijn Tilleman
Margot Van der Jeught
Galbha Duggal
Sylvie Lierman
Mina Popovic
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
et al.
A1
Journal Article
in
MOLECULAR HUMAN REPRODUCTION
2018
2017
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Laurentijn Tilleman
Ella Sutherland
Jasin Taelman
Mina Popovic
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2017
Fertility preservation for trans men : frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing exhibit normal meiotic spindles
Sylvie Lierman
Kelly Tilleman
Kevin Braeckmans
Karen Peynshaert
Steven Weyers
Guy T'Sjoen
Petra De Sutter
A1
Journal Article
in
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
2017
In vitro activation and maturation of primordial follicles of trans men is currently limited by inadequate support of the preantral follicle growth
Chloë De Roo
Kelly Tilleman
Sylvie Lierman
Guy T'Sjoen
Maria Cornelissen
Steven Weyers
Petra De Sutter
C3
Conference
2017
Optimizing in vitro activation and maturation of primordial follicles in transgender and oncological patients
Chloë De Roo
Sylvie Lierman
Guy T'Sjoen
Maria Cornelissen
Steven Weyers
Kelly Tilleman
Petra De Sutter
C3
Conference
2017
Origins of human embryonic stem cell fate : role of the post inner cell mass intermediate
Sharat Warrier
Mina Popovic
Jasin Taelman
Laurentijn Tilleman
Sylvie Lierman
Minerva Ferrer Buitrago
S. Chuva De Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
et al.
C3
Conference
2017
Ovarian tissue cryopreservation in female-to-male transgender people : insights into ovarian histology and physiology after prolonged androgen treatment
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Karen Peynshaert
Kevin Braeckmans
Mirte Caanen
Cornelis Lambalk
Steven Weyers
Guy T'Sjoen
Maria Cornelissen
et al.
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2017
2016
Anti-Müllerian hormone (AMH) serum levels enable preoperative estimation of the number of cumulus-oocyte complexes (COC) in female-to-male transgender persons (trans men)
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Steven Weyers
Guy T'Sjoen
Petra De Sutter
C3
Conference
2016
Cumulus growth pattern of in-vitro matured cumulus-oocyte-complexes (COC) of transsexual persons obtained during cryopreservation of ovarian tissue correlates with the maturation status
Sylvie Lierman
Kelly Tilleman
Chloë De Roo
Steven Weyers
Guy T'Sjoen
Petra De Sutter
C3
Conference
2016
Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells
Sharat Warrier
Margot Van der Jeught
Galbha Duggal
Jasin Taelman
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
et al.
C3
Conference
2016
2015
Alternative routes to induce naive pluripotency in human embryonic stem cells
Galbha Duggal
Sharat Warrier
Sabitri Ghimire
Dorien Broekaert
Margot Van der Jeught
Sylvie Lierman
Tom Deroo
Luc Peelman
Ann Van Soom
Maria Cornelissen
et al.
A1
Journal Article
in
STEM CELLS
2015
Anti-Müllerian Hormone (AMH) serum levels are correlated with the number of intermediate and primary follicles in ovaries of female-to-male transgender persons
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Maria Cornelissen
Steven Weyers
Guy T'Sjoen
Petra De Sutter
C3
Conference
2015
Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation
Margot Van der Jeught
Jasin Taelman
Galbha Duggal
Sabitri Ghimire
Sylvie Lierman
Susana Marina Chuva de Sousa Lopes
Dieter Deforce
Tom Deroo
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
CELLULAR REPROGRAMMING
2015
Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells
Sharat Warrier
Galbha Duggal
Jasin Taelman
Sylvie Lierman
S Chuva de Sousa Lopes
Ann Van Soom
Luc Peelman
Filip Van Nieuwerburgh
Dieter De Coninck
Björn Menten
et al.
C3
Conference
2015
Follicles of various maturation stages react differently to enzymatic isolation: a comparison of different isolation protocols
Sylvie Lierman
Kelly Tilleman
Maria Cornelissen
Winnok De Vos
Steven Weyers
Guy T'Sjoen
Claude Cuvelier
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2015
Frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing, for the purpose of fertility preservation for transsexual persons, show normal spindle formations
Sylvie Lierman
Kelly Tilleman
Chloë De Roo
Kevin Braeckmans
Karen Peynshaert
Steven Weyers
Guy T'Sjoen
Petra De Sutter
C3
Conference
2015
Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos
Sabitri Ghimire
Björn Heindryckx
Margot Van der Jeught
Jitesh Neupane
Thomas O'Leary
Sylvie Lierman
Winnok De Vos
Susana Marina Chuva de Sousa Lopes
Tom Deroo
Petra De Sutter
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2015
2014
A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Sabitri Ghimire
Yuechao Lu
Chen Qian
Sylvie Lierman
Rudy Van Coster
Jan Gerris
Tom Deroo
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2014
Anti-Mülleriaans hormoon (AMH) serumspiegels zijn gecorreleerd met het aantal primaire follikels in ovaria van transgender personen
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Maria Cornelissen
Steven Weyers
Petra De Sutter
C3
Conference
2014
Anti-Müllerian hormone (AMH) serum levels are correlated with the number of primary follicles in ovaries of female-to-male transgender persons
Chloë De Roo
Sylvie Lierman
Kelly Tilleman
Maria Cornelissen
Steven Weyers
Guy T'Sjoen
Petra De Sutter
C3
Conference
2014
In-vitro maturation of cumulus enclosed oocytes collected from the remaining medulla tissue at the time of ovarian tissue cryopreservation
Sylvie Lierman
Kelly Tilleman
Chloë De Roo
Maria Cornelissen
Winnok De Vos
Steven Weyers
Guy T'Sjoen
Claude Cuvelier
Petra De Sutter
C3
Conference
2014
Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death
Fang Li
Volkan Turan
Sylvie Lierman
Claude Cuvelier
Petra De Sutter
Kutluk Oktay
A1
Journal Article
in
HUMAN REPRODUCTION
2014
Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation
Margot Van der Jeught
Björn Heindryckx
Thomas O'Leary
Galbha Duggal
Sabitri Ghimire
Sylvie Lierman
Nadine Van Roy
Susana Marina Chuva de Sousa Lopes
Tom Deroo
Dieter Deforce
et al.
A1
Journal Article
in
HUMAN REPRODUCTION
2014
Vitrification of human blastocysts previously cryopreserved by slow controlled-rate freezing at the cleavage stage
Sylvie Lierman
Etienne Van den Abbeel
Petra De Sutter
A1
Journal Article
in
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
2014
2013
Comparison of different enzymatic isolation protocols for human ovarian follicles: in search for use in a clinical cleanroom setting
Sylvie Lierman
Kelly Tilleman
Petra De Sutter
C3
Conference
2013
Comparison of pre- and post-implantation development following the application of three artificial activating stimuli in a mouse model with round-headed sperm cells deficient for oocyte activation
Frauke Vanden Meerschaut
Dimitra Nikiforaki
Chloë De Roo
Sylvie Lierman
Chen Qian
T Schmitt-John
Petra De Sutter
Björn Heindryckx
A1
Journal Article
in
HUMAN REPRODUCTION
2013
Derivation of human embryonic stem cells using a post-inner cell mass intermediate
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
Margot Van der Jeught
Galbha Duggal
Petra De Sutter
Susana M Chuva de Sousa Lopes
A1
Journal Article
in
NATURE PROTOCOLS
2013
Evaluation of calcium machinery in a meiosis defect mouse model
Yuechao Lu
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Jitesh Neupane
Winnok De Vos
Sylvie Lierman
Tom Deroo
Björn Heindryckx
Petra De Sutter
C3
Conference
2013
Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential
Galbha Duggal
Björn Heindryckx
Sharat Warrier
Thomas O'Leary
Margot Van der Jeught
Sylvie Lierman
Liesbeth Vossaert
Tom Deroo
Dieter Deforce
Susana Marina Chuva de Sousa Lopes
et al.
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2013
Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Tom Deroo
Yuechao Lu
Sabitri Ghimire
Sylvie Lierman
Chen Qian
Dieter Deforce
Petra De Sutter
C3
Conference
2013
The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation
Margot Van der Jeught
Thomas O'Leary
Sabitri Ghimire
Sylvie Lierman
Galbha Duggal
Karen Versieren
Dieter Deforce
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2013
2012
Calciumpatroonanalyse tijdens eicelrijping en na toepassing van geassisteerde eicelactivatie
Chloë De Roo
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Yuechao Lu
Sylvie Lierman
Chen Qian
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Comparison of the effect of ionomycin versus calcimycin on the intracellular calcium level in mouse and human oocytes and subsequent oocyte activation
Frauke Vanden Meerschaut
Chloë De Roo
Dimitra Nikiforaki
Sylvie Lierman
Chen Qian
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Dose-dependent effect of inhibition of the transforming growth factor beta pathway during early mouse lineage segregation
Sabitri Ghimire
Margot Van der Jeught
Jitesh Neupane
Sylvie Lierman
Thomas O'Leary
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
Influence of hESC derivation conditions on germ cell differentiation potential
Galbha Duggal
Björn Heindryckx
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
Susana Chuva de Sousa Lopes
Petra De Sutter
C3
Conference
2012
Influence of human sperm motility and cryopreservation on the oocyte activating factor phospholipase C zeta
Björn Heindryckx
Dimitra Nikiforaki
Frauke Vanden Meerschaut
Winnok De Vos
Sylvie Lierman
Petra De Sutter
C3
Conference
2012
Morphological survival of twice-cryopreserved human embryos
Sylvie Lierman
Ilse De Croo
Björn Heindryckx
Etienne Van den Abbeel
Petra De Sutter
C3
Conference
2012
Pronuclear transfer in mice yields minimal mitochondrial DNA carry-over
Mado Vandewoestyne
Jitesh Neupane
Björn Heindryckx
Sylvie Lierman
Dieter Deforce
Petra De Sutter
C3
Conference
2012
Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model
Jitesh Neupane
Mado Vandewoestyne
Björn Heindryckx
Sabitri Ghimire
Yuechao Lu
Sylvie Lierman
Chen Qian
Dieter Deforce
Petra De Sutter
C3
Conference
2012
The TGFβ pathway plays a pivotal role in early embryo lineage segregation
Margot Van der Jeught
Sabitri Ghimire
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
The influence of patient and cohort parameters on the incidence and developmental potential of embryos with poor quality traits for use in human embryonic stem cell derivation
Thomas O'Leary
Galbha Duggal
Sylvie Lierman
Etienne Van den Abbeel
Björn Heindryckx
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2012
Tracking the progression of the human inner cell mass during embryonic stem cell derivation
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
David van Bruggen
Jelle J Goeman
Mado Vandewoestyne
Dieter Deforce
Susana M Chuva de Sousa Lopes
Petra De Sutter
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2012
Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation
Margot Van der Jeught
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
Susana Chuva de Sousa Lopes
Björn Heindryckx
Petra De Sutter
C3
Conference
2012
2011
Aberrant spindle structures responsible for recurrent human metaphase I oocyte arrest with attempts to induce meiosis artificially
Björn Heindryckx
Sylvie Lierman
CM Combelles
Claude Cuvelier
Jan Gerris
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2011
Culture optimisation to direct differentiation of human embryonic stem cells into primordial germ cells
Galbha Duggal
Björn Heindryckx
Thomas O'Leary
Sylvie Lierman
Dieter Deforce
S Chuva de Sousa Lopes
Petra De Sutter
C3
Conference
2011
Efficiency of polarized microscopy as a predictive tool for human oocyte quality
Björn Heindryckx
Stefanie De Gheselle
Sylvie Lierman
Jan Gerris
Petra De Sutter
A1
Journal Article
in
HUMAN REPRODUCTION
2011
Slow controlled-rate freezing of human in vitro matured oocytes: effects on maturation rate and kinetics, parthenogenesis and spindle structure
Karen Versieren
Björn Heindryckx
Ilse De Croo
Sylvie Lierman
Winnok De Vos
Esther Van den Abbeel
Jan Gerris
Petra De Sutter
C3
Conference
2011
The influence of early embryo traits on human embryonic stem cell derivation efficiency
Thomas O'Leary
Björn Heindryckx
Sylvie Lierman
Margot Van der Jeught
Björn Menten
Dieter Deforce
Maria Cornelissen
Susana Chuva de Sousa Lopes
Petra De Sutter
A1
Journal Article
in
STEM CELLS AND DEVELOPMENT
2011
2010
Comparison of three artificial activating stimuli using a mouse model deficient for oocyte activation
Björn Heindryckx
Frauke Vanden Meerschaut
Sylvie Lierman
Chen Qian
Thomas O'Leary
Jan Gerris
Petra De Sutter
C3
Conference
2010
Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation
Karen Versieren
Björn Heindryckx
Sylvie Lierman
Jan Gerris
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2010
2008
Effect of ionomycin on oocyte activation and embryo development in mouse
Elke Heytens
Reza Soleimani
Sylvie Lierman
Simon De Meester
Jan Gerris
Marc Dhont
Josiane Van der Elst
Petra De Sutter
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2008
2007
Co-culture of pre-antral ovarian follicles does not increase the yield of in-vitro-matured oocytes in the mouse
Sylvie Lierman
Petra De Sutter
J LIU
Jan Gerris
Marc Dhont
Josiane Van der Elst
A1
Journal Article
in
REPRODUCTIVE BIOMEDICINE ONLINE
2007
Double-quality control reveals high-level toxicity in gloves used for operator protection in assisted reproductive technology
Sylvie Lierman
Petra De Sutter
Marc Dhont
Josiane Van der Elst
A1
Journal Article
in
FERTILITY AND STERILITY
2007
Ionophore treatment of mouse oocytes injected with human round-headed sperm does not lead to subsequent normal calcium oscillation pattern
Elke Heytens
Leen Vanhoutte
Sylvie Lierman
Claude Cuvelier
Jan Gerris
Marc Dhont
Petra De Sutter
Luc Leybaert
C3
Conference
2007
Mouse back muscle as a promising site for human ovarian tissue xenotransplantation
Reza Soleimani
Elke Heytens
Sylvie Lierman
Claude Cuvelier
Jan Gerris
Marc Dhont
Josiane Van der Elst
Petra De Sutter
C3
Conference
2007
2006
Influence of sperm preparation gradient on fertilization failure in IVF
Sylvie Lierman
A VAN DE VELDE
Chen Qian
F MAHIEU
Petra De Sutter
Jan Gerris
Marc Dhont
Josiane Van der Elst
C3
Conference
2006
Two novel techniques to detect follicles in human ovarian cortical tissue
Reza Soleimani
Winnok De Vos
Patric Van Oostveldt
Sylvie Lierman
Rudy Van den Broecke
Petra De Sutter
Marc Dhont
Josiane Van der Elst
A1
Journal Article
in
HUMAN REPRODUCTION
2006
2004
Chromosome number and development of artificial mouse oocytes and zygotes
Björn Heindryckx
Sylvie Lierman
Josiane Van der Elst
Marc Dhont
A1
Journal Article
in
HUMAN REPRODUCTION
2004
In vitro follicle interaction can influence oocyte maturation in co-cultured pairs of preantral mouse ovarian follicles
Sylvie Lierman
Jun Liu
Josiane Van der Elst
Marc Dhont
C1
Conference
2004
2003
De muizenoöcytactivatietest en geassisteerde eicelactivatie bij ICSI
Björn Heindryckx
Sylvie Lierman
Petra De Sutter
Josiane Van der Elst
Marc Dhont
A2
Journal Article
in
TIJDSCHRIFT VOOR FERTILITEITSONDERZOEK
2003