Research Explorer

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Researcher

Sylvie Lierman

Awards & Distinctions

70 Results

2021

Low feasibility of in vitro matured oocytes originating from cumulus complexes found during ovarian tissue preparation at the moment of gender confirmation surgery and during testosterone treatment for fertility preservation in transgender men

Sylvie LiermanAnnelies TolpeIlse De CrooStefanie De GheselleJustine DefreyneMachteld BaetensAnnelies DheedeneRoos ColmanBjörn MentenGuy T'Sjoen et al.

A1 Journal Article in FERTILITY AND STERILITY

Passive slow freezing is an efficacious and cost-effective alternative to controlled slow freezing for ovarian tissue cryopreservation

Sylvie LiermanA. BusS. AndriesE. TriasP. E. J. BolsKelly Tilleman

A1 Journal Article in CRYOBIOLOGY

2020

In vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway

Chloë De RooSylvie LiermanKelly TillemanPetra De Sutter

In-vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway

Chloë De RooSylvie LiermanKelly TillemanPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION OPEN

Swim-up as a strategy for isolation of spermatozoa without viral incorporation in men with chronic hepatitis B : a pilot study

Thomas CondijtsLiesl Bourdeaud'huyKelly TillemanSylvie LiermanChantal DewinterElizaveta Padalko

A1 Journal Article in ANDROLOGIA

Treating transgender people

Kelly TillemanChloë De RooSylvie LiermanPetra De Sutter

Bookchapter in Textbook of assisted reproduction

2019

Endometrial stromal cell proteome mapping in repeated implantation failure and recurrent pregnancy loss cases and fertile women

Lien DhaenensSylvie LiermanLaura De ClerckElisabeth GovaertDieter DeforceKelly TillemanPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

2018

Ovarian tissue cryopreservation in female-to-male transgender persons : insights in ovarian histology and physiology after prolonged androgen treatment

Chloë De RooSylvie LiermanKelly TillemanKaren PeynshaertKevin BraeckmansMirte CaanenCornelis LambalkSteven WeyersPetra De Sutter

Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes

Yuechao LuMinerva Ferrer BuitragoMina PopovicJitesh NeupaneWinnok De VosSylvie LiermanEtienne Van den AbbeelMargot Van der JeughtDimitra NikiforakiPetra De Sutter et al.

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Strontium fails to induce Ca2+ release and activation in human oocytes despite the presence of functional TRPV3 channels

Y LuR ReddyMinerva Ferrer BuitragoMargot Van der JeughtJitesh NeupaneWinnok De VosEtienne Van den AbbeelSylvie LiermanPetra De SutterBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION OPEN

Transcriptional landscape changes during human embryonic stem cell derivation

Sharat WarrierJasin TaelmanLaurentijn TillemanMargot Van der JeughtGalbha DuggalSylvie LiermanMina PopovicAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

2017

Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalLaurentijn TillemanElla SutherlandJasin TaelmanMina PopovicSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van Soom et al.

A1 Journal Article in NATURE COMMUNICATIONS

Fertility preservation for trans men : frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing exhibit normal meiotic spindles

Sylvie LiermanKelly TillemanKevin BraeckmansKaren PeynshaertSteven WeyersGuy T'SjoenPetra De Sutter

A1 Journal Article in JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

In vitro activation and maturation of primordial follicles of trans men is currently limited by inadequate support of the preantral follicle growth

Chloë De RooKelly TillemanSylvie LiermanGuy T'SjoenMaria CornelissenSteven WeyersPetra De Sutter

Optimizing in vitro activation and maturation of primordial follicles in transgender and oncological patients

Chloë De RooSylvie LiermanGuy T'SjoenMaria CornelissenSteven WeyersKelly TillemanPetra De Sutter

Origins of human embryonic stem cell fate : role of the post inner cell mass intermediate

Sharat WarrierMina PopovicJasin TaelmanLaurentijn TillemanSylvie LiermanMinerva Ferrer BuitragoS. Chuva De Sousa LopesAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

Ovarian tissue cryopreservation in female-to-male transgender people : insights into ovarian histology and physiology after prolonged androgen treatment

Chloë De RooSylvie LiermanKelly TillemanKaren PeynshaertKevin BraeckmansMirte CaanenCornelis LambalkSteven WeyersGuy T'SjoenMaria Cornelissen et al.

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

2016

Anti-Müllerian hormone (AMH) serum levels enable preoperative estimation of the number of cumulus-oocyte complexes (COC) in female-to-male transgender persons (trans men)

Chloë De RooSylvie LiermanKelly TillemanSteven WeyersGuy T'SjoenPetra De Sutter

Cumulus growth pattern of in-vitro matured cumulus-oocyte-complexes (COC) of transsexual persons obtained during cryopreservation of ovarian tissue correlates with the maturation status

Sylvie LiermanKelly TillemanChloë De RooSteven WeyersGuy T'SjoenPetra De Sutter

Uncovering the novel role of mTORC2 subunit of the PI3K/AKT/mTORC pathway in establishing naive pluripotency in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalJasin TaelmanSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De Coninck et al.

2015

Alternative routes to induce naive pluripotency in human embryonic stem cells

Galbha DuggalSharat WarrierSabitri GhimireDorien BroekaertMargot Van der JeughtSylvie LiermanTom DerooLuc PeelmanAnn Van SoomMaria Cornelissen et al.

A1 Journal Article in STEM CELLS

Anti-Müllerian Hormone (AMH) serum levels are correlated with the number of intermediate and primary follicles in ovaries of female-to-male transgender persons

Chloë De RooSylvie LiermanKelly TillemanMaria CornelissenSteven WeyersGuy T'SjoenPetra De Sutter

Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation

Margot Van der JeughtJasin TaelmanGalbha DuggalSabitri GhimireSylvie LiermanSusana Marina Chuva de Sousa LopesDieter DeforceTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in CELLULAR REPROGRAMMING

Comparative analysis of different culture conditions inducing naive pluripotency in human embryonic stem cells

Sharat WarrierGalbha DuggalJasin TaelmanSylvie LiermanS Chuva de Sousa LopesAnn Van SoomLuc PeelmanFilip Van NieuwerburghDieter De ConinckBjörn Menten et al.

Follicles of various maturation stages react differently to enzymatic isolation: a comparison of different isolation protocols

Sylvie LiermanKelly TillemanMaria CornelissenWinnok De VosSteven WeyersGuy T'SjoenClaude CuvelierPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing, for the purpose of fertility preservation for transsexual persons, show normal spindle formations

Sylvie LiermanKelly TillemanChloë De RooKevin BraeckmansKaren PeynshaertSteven WeyersGuy T'SjoenPetra De Sutter

Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos

Sabitri GhimireBjörn HeindryckxMargot Van der JeughtJitesh NeupaneThomas O'LearySylvie LiermanWinnok De VosSusana Marina Chuva de Sousa LopesTom DerooPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2014

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianSylvie LiermanRudy Van CosterJan GerrisTom Deroo et al.

A1 Journal Article in HUMAN REPRODUCTION

Anti-Mülleriaans hormoon (AMH) serumspiegels zijn gecorreleerd met het aantal primaire follikels in ovaria van transgender personen

Chloë De RooSylvie LiermanKelly TillemanMaria CornelissenSteven WeyersPetra De Sutter

Anti-Müllerian hormone (AMH) serum levels are correlated with the number of primary follicles in ovaries of female-to-male transgender persons

Chloë De RooSylvie LiermanKelly TillemanMaria CornelissenSteven WeyersGuy T'SjoenPetra De Sutter

In-vitro maturation of cumulus enclosed oocytes collected from the remaining medulla tissue at the time of ovarian tissue cryopreservation

Sylvie LiermanKelly TillemanChloë De RooMaria CornelissenWinnok De VosSteven WeyersGuy T'SjoenClaude CuvelierPetra De Sutter

Sphingosine-1-phosphate prevents chemotherapy-induced human primordial follicle death

Fang LiVolkan TuranSylvie LiermanClaude CuvelierPetra De SutterKutluk Oktay

A1 Journal Article in HUMAN REPRODUCTION

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtBjörn HeindryckxThomas O'LearyGalbha DuggalSabitri GhimireSylvie LiermanNadine Van RoySusana Marina Chuva de Sousa LopesTom DerooDieter Deforce et al.

A1 Journal Article in HUMAN REPRODUCTION

Vitrification of human blastocysts previously cryopreserved by slow controlled-rate freezing at the cleavage stage

Sylvie LiermanEtienne Van den AbbeelPetra De Sutter

A1 Journal Article in JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

2013

Comparison of different enzymatic isolation protocols for human ovarian follicles: in search for use in a clinical cleanroom setting

Sylvie LiermanKelly TillemanPetra De Sutter

Comparison of pre- and post-implantation development following the application of three artificial activating stimuli in a mouse model with round-headed sperm cells deficient for oocyte activation

Frauke Vanden MeerschautDimitra NikiforakiChloë De RooSylvie LiermanChen QianT Schmitt-JohnPetra De SutterBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

Derivation of human embryonic stem cells using a post-inner cell mass intermediate

Thomas O'LearyBjörn HeindryckxSylvie LiermanMargot Van der JeughtGalbha DuggalPetra De SutterSusana M Chuva de Sousa Lopes

A1 Journal Article in NATURE PROTOCOLS

Evaluation of calcium machinery in a meiosis defect mouse model

Yuechao LuDimitra NikiforakiFrauke Vanden MeerschautJitesh NeupaneWinnok De VosSylvie LiermanTom DerooBjörn HeindryckxPetra De Sutter

Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential

Galbha DuggalBjörn HeindryckxSharat WarrierThomas O'LearyMargot Van der JeughtSylvie LiermanLiesbeth VossaertTom DerooDieter DeforceSusana Marina Chuva de Sousa Lopes et al.

A1 Journal Article in STEM CELLS AND DEVELOPMENT

Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxTom DerooYuechao LuSabitri GhimireSylvie LiermanChen QianDieter DeforcePetra De Sutter

The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation

Margot Van der JeughtThomas O'LearySabitri GhimireSylvie LiermanGalbha DuggalKaren VersierenDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2012

Calciumpatroonanalyse tijdens eicelrijping en na toepassing van geassisteerde eicelactivatie

Chloë De RooDimitra NikiforakiFrauke Vanden MeerschautYuechao LuSylvie LiermanChen QianBjörn HeindryckxPetra De Sutter

Comparison of the effect of ionomycin versus calcimycin on the intracellular calcium level in mouse and human oocytes and subsequent oocyte activation

Frauke Vanden MeerschautChloë De RooDimitra NikiforakiSylvie LiermanChen QianBjörn HeindryckxPetra De Sutter

Dose-dependent effect of inhibition of the transforming growth factor beta pathway during early mouse lineage segregation

Sabitri GhimireMargot Van der JeughtJitesh NeupaneSylvie LiermanThomas O'LearySusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

Influence of hESC derivation conditions on germ cell differentiation potential

Galbha DuggalBjörn HeindryckxThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesPetra De Sutter

Influence of human sperm motility and cryopreservation on the oocyte activating factor phospholipase C zeta

Björn HeindryckxDimitra NikiforakiFrauke Vanden MeerschautWinnok De VosSylvie LiermanPetra De Sutter

Morphological survival of twice-cryopreserved human embryos

Sylvie LiermanIlse De CrooBjörn HeindryckxEtienne Van den AbbeelPetra De Sutter

Pronuclear transfer in mice yields minimal mitochondrial DNA carry-over

Mado VandewoestyneJitesh NeupaneBjörn HeindryckxSylvie LiermanDieter DeforcePetra De Sutter

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuSylvie LiermanChen QianDieter DeforcePetra De Sutter

The TGFβ pathway plays a pivotal role in early embryo lineage segregation

Margot Van der JeughtSabitri GhimireThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

The influence of patient and cohort parameters on the incidence and developmental potential of embryos with poor quality traits for use in human embryonic stem cell derivation

Thomas O'LearyGalbha DuggalSylvie LiermanEtienne Van den AbbeelBjörn HeindryckxPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Tracking the progression of the human inner cell mass during embryonic stem cell derivation

Thomas O'LearyBjörn HeindryckxSylvie LiermanDavid van BruggenJelle J GoemanMado VandewoestyneDieter DeforceSusana M Chuva de Sousa LopesPetra De Sutter

A1 Journal Article in NATURE BIOTECHNOLOGY

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

2011

Aberrant spindle structures responsible for recurrent human metaphase I oocyte arrest with attempts to induce meiosis artificially

Björn HeindryckxSylvie LiermanCM CombellesClaude CuvelierJan GerrisPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Culture optimisation to direct differentiation of human embryonic stem cells into primordial germ cells

Galbha DuggalBjörn HeindryckxThomas O'LearySylvie LiermanDieter DeforceS Chuva de Sousa LopesPetra De Sutter

Efficiency of polarized microscopy as a predictive tool for human oocyte quality

Björn HeindryckxStefanie De GheselleSylvie LiermanJan GerrisPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Slow controlled-rate freezing of human in vitro matured oocytes: effects on maturation rate and kinetics, parthenogenesis and spindle structure

Karen VersierenBjörn HeindryckxIlse De CrooSylvie LiermanWinnok De VosEsther Van den AbbeelJan GerrisPetra De Sutter

The influence of early embryo traits on human embryonic stem cell derivation efficiency

Thomas O'LearyBjörn HeindryckxSylvie LiermanMargot Van der JeughtBjörn MentenDieter DeforceMaria CornelissenSusana Chuva de Sousa LopesPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2010

Comparison of three artificial activating stimuli using a mouse model deficient for oocyte activation

Björn HeindryckxFrauke Vanden MeerschautSylvie LiermanChen QianThomas O'LearyJan GerrisPetra De Sutter

Developmental competence of parthenogenetic mouse and human embryos after chemical or electrical activation

Karen VersierenBjörn HeindryckxSylvie LiermanJan GerrisPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

2008

Effect of ionomycin on oocyte activation and embryo development in mouse

Elke HeytensReza SoleimaniSylvie LiermanSimon De MeesterJan GerrisMarc DhontJosiane Van der ElstPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

2007

Co-culture of pre-antral ovarian follicles does not increase the yield of in-vitro-matured oocytes in the mouse

Sylvie LiermanPetra De SutterJ LIUJan GerrisMarc DhontJosiane Van der Elst

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Double-quality control reveals high-level toxicity in gloves used for operator protection in assisted reproductive technology

Sylvie LiermanPetra De SutterMarc DhontJosiane Van der Elst

A1 Journal Article in FERTILITY AND STERILITY

Ionophore treatment of mouse oocytes injected with human round-headed sperm does not lead to subsequent normal calcium oscillation pattern

Elke HeytensLeen VanhoutteSylvie LiermanClaude CuvelierJan GerrisMarc DhontPetra De SutterLuc Leybaert

Mouse back muscle as a promising site for human ovarian tissue xenotransplantation

Reza SoleimaniElke HeytensSylvie LiermanClaude CuvelierJan GerrisMarc DhontJosiane Van der ElstPetra De Sutter

2006

Influence of sperm preparation gradient on fertilization failure in IVF

Sylvie LiermanA VAN DE VELDEChen QianF MAHIEUPetra De SutterJan GerrisMarc DhontJosiane Van der Elst

Two novel techniques to detect follicles in human ovarian cortical tissue

Reza SoleimaniWinnok De VosPatric Van OostveldtSylvie LiermanRudy Van den BroeckePetra De SutterMarc DhontJosiane Van der Elst

A1 Journal Article in HUMAN REPRODUCTION

2004

Chromosome number and development of artificial mouse oocytes and zygotes

Björn HeindryckxSylvie LiermanJosiane Van der ElstMarc Dhont

A1 Journal Article in HUMAN REPRODUCTION

In vitro follicle interaction can influence oocyte maturation in co-cultured pairs of preantral mouse ovarian follicles

Sylvie LiermanJun LiuJosiane Van der ElstMarc Dhont

2003

De muizenoöcytactivatietest en geassisteerde eicelactivatie bij ICSI

Björn HeindryckxSylvie LiermanPetra De SutterJosiane Van der ElstMarc Dhont

A2 Journal Article in TIJDSCHRIFT VOOR FERTILITEITSONDERZOEK