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Researcher
Sylvia Van Dorpe
Profile
Projects
Publications
Activities
Awards & Distinctions
41
Results
2014
The effect of prolonged exposure to morphine on canine cerebral 5-HT2A receptors measured with 123I-R91150 SPECT
Antita Adriaens
Ingeborgh Polis
Simon Vermeire
Tim Waelbers
Siska Croubels
Luc Duchateau
Sylvia Van Dorpe
Jos Eersels
Bart De Spiegeleer
Kathelijne Peremans
A1
Journal Article
in
EUROPEAN NEUROPSYCHOPHARMACOLOGY
2014
2013
Reversed-phase fused-core HPLC modeling of peptides
Matthias D'Hondt
Bert Gevaert
Sofie Stalmans
Sylvia Van Dorpe
Evelien Wynendaele
Kathelijne Peremans
Christian Paul G. Burvenich
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF PHARMACEUTICAL ANALYSIS
2013
2012
Analytical characterization of the blood-brain barrier transport of peptides
Sylvia Van Dorpe
Bart De Spiegeleer
Dissertation
2012
Api88 is a novel antibacterial designer peptide to treat systemic infections with multidrug-resistant Gram-negative pathogens
Patricia Czihal
Daniel Knappe
Stefanie Fritsche
Michael Zahn
Nicole Berthold
Stefania Piantavigna
Uwe Müller
Sylvia Van Dorpe
Nicole Herth
Annegret Binas
et al.
A1
Journal Article
in
ACS CHEMICAL BIOLOGY
2012
Blood-brain barrier modelling of bioactive peptides
Bart De Spiegeleer
Matthias D'Hondt
Sofie Stalmans
Sylvia Van Dorpe
C3
Conference
2012
Brainpeps: the blood-brain barrier peptide database
Sylvia Van Dorpe
Antoon Bronselaer
Joachim Nielandt
Sofie Stalmans
Evelien Wynendaele
Kurt Audenaert
Christophe Van De Wiele
Christian Paul G. Burvenich
Kathelijne Peremans
Hung Hsuchou
et al.
A1
Journal Article
in
BRAIN STRUCTURE & FUNCTION
2012
In vitro metabolic stability of iodinated obestatin peptides
Bart De Spiegeleer
Sylvia Van Dorpe
Valentijn Vergote
Evelien Wynendaele
Ewald Pauwels
Christophe Van De Wiele
Pablo Garcia-Solis
Juan Carlos Solis-Sainz
A1
Journal Article
in
PEPTIDES
2012
Stability of extemporaneously prepared cytarabine, methotrexate sodium, and methylprednisolone sodium succinate
Matthias D'Hondt
Elien Vangheluwe
Sylvia Van Dorpe
Jente Boonen
Tieneke Bauters
BRIGITTE PELFRENE
Johan Vandenbroucke
Hugo Robays
Bart De Spiegeleer
A1
Journal Article
in
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
2012
The influence of chronic morphine on the canine cerebral 5-HT2A receptor availability measured with SPECT
Antita Adriaens
Ingeborgh Polis
Simon Vermeire
Eva Vandermeulen
Tim Waelbers
Jos Eersels
André Dobbeleir
Luc Duchateau
Sylvia Van Dorpe
Bart De Spiegeleer
et al.
C3
Conference
2012
The influence of morphine on cerebral 5-HT2A receptor availability in dogs: a SPECT study
Antita Adriaens
Ingeborgh Polis
Simon Vermeire
Tim Waelbers
Luc Duchateau
Stanislas Sys
Sylvia Van Dorpe
Jos Eersels
Bart De Spiegeleer
Kathelijne Peremans
A1
Journal Article
in
JOURNAL OF NUCLEAR MEDICINE
2012
Variation of the net charge, lipophilicity, and side chain flexibility in Dmt¹-DALDA: effect on opioid activity and biodistribution
Alexandre Novoa
Sylvia Van Dorpe
Evelien Wynendaele
Mariana Spetea
Nathalie Bracke
Sofie Stalmans
Cecilia Betti
Nga N Chung
Carole Lemieux
Johannes Zuegg
et al.
A1
Journal Article
in
JOURNAL OF MEDICINAL CHEMISTRY
2012
2011
ADME behaviour of some Dmt-DALDA-peptide derivatives
Sylvia Van Dorpe
Iris Vandenbroeck
Evelien Wynendaele
Mathieu Verbeken
Alexandre Novoa
Dirk Tourwé
Steven Ballet
Bart De Spiegeleer
C3
Conference
2011
Blood-brain barrier and ADME properties of selected DALDA-peptide derivatives
Sylvia Van Dorpe
Evelien Wynendaele
Christian Paul G. Burvenich
Alexandre Novoa
Dirk Tourwé
Steven Ballet
Bart De Spiegeleer
C3
Conference
2011
Blood-brain barrier characteristics of opioid peptides
Sylvia Van Dorpe
Christophe Van De Wiele
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
C3
Conference
2011
Desirability function combining metabolic stability and functionality of peptides
Sylvia Van Dorpe
Antita Adriaens
Simon Vermeire
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PEPTIDE SCIENCE
2011
Dry heat stress stability evaluation of casein peptide mixture
Matthias D'Hondt
Wim Demaré
Sylvia Van Dorpe
Evelien Wynendaele
Christian Paul G. Burvenich
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
FOOD CHEMISTRY
2011
Purity profiling of peptide drugs
Sylvia Van Dorpe
Mathieu Verbeken
Evelien Wynendaele
Bart De Spiegeleer
A2
Journal Article
in
JOURNAL OF BIOANALYSIS AND BIOMEDICINE
2011
Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine
Mathieu Verbeken
Sultan Suleman Wega
Bram Baert
Elien Vangheluwe
Sylvia Van Dorpe
Christian Paul G. Burvenich
Luc Duchateau
Frans H Jansen
Bart De Spiegeleer
A1
Journal Article
in
MALARIA JOURNAL
2011
Structural modification and biological evaluation of Dmt1-DALDA analogues
Alexandre Novoa
Sylvia Van Dorpe
Evelien Wynendaele
Nga Chung
Carole Lemieux
Peter W Schiller
Dirk Tourwé
Bart De Spiegeleer
Steven Ballet
C3
Conference
2011
2010
Analytical characterization and comparison of the blood-brain barrier permeability of eight opioid peptides
Sylvia Van Dorpe
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Jan Van Bocxlaer
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2010
Bioactive peptides as potential new drugs: from analytics to tissue bath functionality
Mathieu Verbeken
Sylvia Van Dorpe
Romain Lefebvre
Bart De Spiegeleer
C3
Conference
2010
Chemical quality control of peptide functionality testing in tissue baths
Mathieu Verbeken
Sylvia Van Dorpe
Romain Lefebvre
Bart De Spiegeleer
C3
Conference
2010
Comparative drugability evaluation of MOR opioid peptides in functional brain research
Bart De Spiegeleer
Sylvia Van Dorpe
Olga Jedlickova
Antita Adriaens
Simon Vermeire
Ingeborgh Polis
Kathelijne Peremans
C3
Conference
2010
Functional differences of iodinated obestatin peptides: in vitro metabolic stability profile
Sylvia Van Dorpe
Ingeborg Wallez
Bart De Spiegeleer
C3
Conference
2010
Functional drugability of MOR-opioid peptides through desirability
Sylvia Van Dorpe
Olga Jedlickova
Antita Adriaens
Tim Waelbers
Simon Vermeire
Ingeborgh Polis
Kathelijne Peremans
Bart De Spiegeleer
C3
Conference
2010
HPLC-MS characterisation of chelate modified somatropin
Evelien Wynendaele
Ewald Pauwels
Sylvia Van Dorpe
Valentijn Vergote
Christophe Van De Wiele
Bart De Spiegeleer
C3
Conference
2010
Hydrophilic interaction LC of peptides: columns comparison and clustering
Sylvia Van Dorpe
Valentijn Vergote
Adel Pezeshki
Christian Paul G. Burvenich
Kathelijne Peremans
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF SEPARATION SCIENCE
2010
LC-MS quality control of modified pharmaceutical proteins : the somatropin case
Evelien Wynendaele
Ewald Pauwels
Christophe Van De Wiele
Sylvia Van Dorpe
Bart De Spiegeleer
C3
Conference
2010
Morphine decreases 5-HT2A receptor binding measured with SPECT in the canine frontal cortex
Antita Adriaens
Simon Vermeire
Tim Waelbers
Luc Duchateau
Stanislas Sys
André Dobbeleir
Sylvia Van Dorpe
J Eersels
Bart De Spiegeleer
Kurt Audenaert
et al.
C3
Conference
2010
Quality analysis of salmon calcitonin in a polymeric bioadhesive pharmaceutical formulation: sample preparation optimization by DOE
Matthias D'Hondt
Sylvia Van Dorpe
Els Mehuys
Dieter Deforce
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2010
The influence of morphine on 5-HT2A receptor availability using SPECT: a preliminary study in dogs
Antita Adriaens
Simon Vermeire
Tim Waelbers
Luc Duchateau
Stanislas Sys
Sylvia Van Dorpe
Jos Eersels
Bart De Spiegeleer
Kathelijne Peremans
Ingeborgh Polis
C3
Conference
2010
The metabolisation of different iodinated peptide species
Bart De Spiegeleer
Sylvia Van Dorpe
Ewald Pauwels
C3
Conference
2010
The metabolisation of different iodinated peptide species
Bart De Spiegeleer
Sylvia Van Dorpe
Ewald Pauwels
C3
Conference
2010
2009
Adsorption of peptides at the sample drying step: influence of solvent evaporation technique, vial material and solution additive
Adel Pezeshki
Valentijn Vergote
Sylvia Van Dorpe
Bram Baert
Christian Paul G. Burvenich
Alexander Popkov
Bart De Spiegeleer
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2009
Analytical characterization of the BBB functionality of the opioid-peptides EM-1, EM-2 and CTAP.
Sylvia Van Dorpe
Nathalie Pintelon
Antita Adriaens
Ingeborgh Polis
Kathelijne Peremans
Weihong Pan
Christian Paul G. Burvenich
Bart De Spiegeleer
C3
Conference
2009
Development of peptide receptor binding assays: methods to avoid false negatives
Valentijn Vergote
Sylvia Van Dorpe
Mathieu Verbeken
Christian Paul G. Burvenich
Christophe Van De Wiele
William Banks
Bart De Spiegeleer
A1
Journal Article
in
REGULATORY PEPTIDES
2009
2008
Development of system suitability tests for in vitro skin integrity control: impedance and capacitance.
Bart De Spiegeleer
Bram Baert
Valentijn Vergote
Sylvia Van Dorpe
C1
Conference
2008
In vitro metabolic stability of obestatin: Kinetics and identification of cleavage products
Valentijn Vergote
Sylvia Van Dorpe
Kathelijne Peremans
Christian Paul G. Burvenich
Bart De Spiegeleer
A1
Journal Article
in
PEPTIDES
2008
Inhibiting protease-activity in peptidomics: strategies during sampling and receptor studies
Valentijn Vergote
Adel Pezeshki
Sylvia Van Dorpe
Christian Paul G. Burvenich
Bart De Spiegeleer
C1
Conference
2008
Pharmaceutical drugability of peptides
Bart De Spiegeleer
Valentijn Vergote
Sylvia Van Dorpe
Bram Baert
Kurt Audenaert
Christophe Van De Wiele
Kathelijne Peremans
Christian Paul G. Burvenich
C3
Conference
2008
Screening methodology for chemical and metabolic stability of potential peptide drugs
Bart De Spiegeleer
Valentijn Vergote
Adel Pezeshki
Sylvia Van Dorpe
Bram Baert
Christian Paul G. Burvenich
C1
Conference
2008