Research Explorer

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Researcher

Sven Mangelinckx

137 Results

2021

Altering the sex pheromone cyclo(L-Pro-L-Pro) of the diatom Seminavis robusta towards a chemical probe

Eli BonneureAmber De BaetsSam De DeckerKoen Van den BergeLieven ClementWim VyvermanSven Mangelinckx

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mating type specific transcriptomic response to sex inducing pheromone in the pennate diatom Seminavis robusta

Gust BilckeKoen Van den BergeSam De DeckerEli BonneureNicole PoulsenPetra BulánkováCristina OsunaJack DickensonKoen SabbeGeorg PohnertKlaas VandepoeleSven MangelinckxLieven ClementLieven De VeylderWim Vyverman

A1 Journal Article in ISME JOURNAL

Plant defense priming in the field : a review

Willem DesmedtBartel VanholmeTina Kyndt

Bookchapter in Recent highlights in the discovery and optimization of crop protection products

Recent highlights in the discovery and optimization of crop protection products

Recent innovation in crop protection research

Peter MaienfischSven Mangelinckx

Bookchapter in Recent highlights in the discovery and optimization of crop protection products

Sampling, separation, and quantification of N-acyl homoserine lactones from marine intertidal sediments

Frederike Stock genannt SchroerEmilio CirriSamarasinghe Gunasekara Liyanage Ishari NuwanthiWillem StockNico UeberschaarSven MangelinckxGeorg PohnertWim Vyverman

A1 Journal Article in LIMNOLOGY AND OCEANOGRAPHY-METHODS

2020

A phytochemical perspective on plant defense against nematodes

Willem DesmedtSven MangelinckxTina KyndtBartel Vanholme

A1 Journal Article in FRONTIERS IN PLANT SCIENCE

Development of antimalarial quinoline-based conjugates and anticancer nitroxoline derivatives

Tim Van de WalleMatthias D'hoogheSven Mangelinckx

Distinctive growth and transcriptional changes of the diatom Seminavis robusta in response to quorum sensing related compounds

Frederike Stock genannt SchroerGust BilckeSam De DeckerCristina OsunaKoen Van den BergeEmmelien VancaesterLieven De VeylderKlaas VandepoeleSven MangelinckxWim Vyverman

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Synthesis and biological evaluation of novel quinoline-piperidine scaffolds as antiplasmodium agents

Tim Van de WalleMaya BooneJulie Van PuyveldeJill CombrinckPeter J. SmithKelly ChibaleSven MangelinckxMatthias D'hooghe

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel nitroxoline analogs with potent cathepsin B exopeptidase inhibitory activity

Tim Van de WalleMarina BriandAna MitrovićIzidor SosičStanislav GobecJanko KosLeentje PersoonsDirk DaelemansSteven De JongheZorica UbiparipTom DesmetKristof Van HeckeSven MangelinckxMatthias D'hooghe

A1 Journal Article in CHEMMEDCHEM

The phytochemical composition of Melia volkensii and its potential for insect pest management

Victor JaokoNji Tizi Clauvis TaningSimon BackxJackson MulatyaJan Van den AbeeleTitus MagomereFlorence OlubayoSven MangelinckxStefaan WerbrouckGuy Smagghe

A1 Journal Article in Plants

The use of PTI-marker genes to identify novel compounds that establish induced resistance in rice

Jonas De KeselRamsés Gómez RodríguezEli BonneureSven MangelinckxTina Kyndt

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2019

Bioactivity-guided isolation of rosmarinic acid as the principal bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum

Saira KhanNji Tizi Clauvis TaningEli BonneureSven MangelinckxGuy SmaggheRaza AhmadNighat FatimaMuhammad AsifMohammad Maroof Shah

A1 Journal Article in PLOS ONE

Bioactivity-guided isolation of rosmarinic acid as the principal bioactive compound from the butanol extract of Isodon rugosus against the pea aphid, Acyrthosiphon pisum (vol 14, e0215048, 2019)

Saira KhanNji Tizi Clauvis TaningEli BonneureSven MangelinckxGuy SmaggheRaza AhmadNighat FatimaMuhammad AsifMohammad Maroof Shah

Bioactivity-guided isolation of rosmarinic acid as the principle bioactive compound from the butanol extract of Isodon rugosus against pea aphid, Acyrthosiphon pisum

Saira KhanNji Tizi Clauvis TaningEli BonneureSven MangelinckxGuy SmaggheRaza AhmadNighat FatimaMuhammad AsifMohammad Maroof Shah

Characterisation of the bioactivity of pesticidal extracts of Melia volkensii against African crop insect pests

Victor JaokoNji Tizi Clauvis TaningSimon BackxJackson MulatyaJan VandenabeeleFlorence OlubayoSven MangelinckxStefaan WerbrouckGuy Smagghe

Diatom-bacteria consortia from marine biofilms : assembly, interactions and adaptations

Willem StockKoen SabbeAnne WillemsSven MangelinckxWim Vyverman

Diatom-bacteria interactions modulate the composition and productivity of benthic diatom biofilms

Coco KoedooderWillem StockAnne WillemsSven MangelinckxMarleen De TrochWim VyvermanKoen Sabbe

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Evaluating the efficacy of Melia volkensii extracts as a potential botanical pesticide against African crop insect pests of economic importance

Victor JaokoNji Tizi Clauvis TaningSimon BackxJackson MulatyaJan VandenabeeleFlorence OlubayoSven MangelinckxStefaan WerbrouckGuy Smagghe

Evaluation of Melia volkensii as potential biopesticide against the African sweet potato weevil, Cylas puncticollis

Victor JaokoNji Tizi Clauvis TaningSimon BackxJackson MulatyaJan VandenabeeleFlorence OlubayoSven MangelinckxStefaan WerbrouckGuy Smagghe

Host specificity in diatom-bacteria interactions alleviates antagonistic effects

Willem StockLander BlommaertMarleen De TrochSven MangelinckxAnne WillemsWim VyvermanKoen Sabbe

A1 Journal Article in FEMS MICROBIOLOGY ECOLOGY

Identification of a new algicidal compound derived from quorum sensing signalling molecules

Simon BackxFrederike Stock genannt SchroerShiri Graff van CreveldMichail SyrpasLander BlommaertWillem StockEwout RuysberghKoen SabbeNorbert De KimpeAnne WillemsAssaf VardiWim VyvermanSven Mangelinckx

Influence of the algal microbiome on biofouling during industrial cultivation of Nannochloropsis sp. in closed photobioreactors

Javier B. GiraldoWillem StockLachlan DowLuc RoefAnne WillemsSven MangelinckxPeter G. KrothWim VyvermanMark Michiels

A1 Journal Article in ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS

N-Acyl homoserine lactone derived tetramic acids impair photosynthesis in Phaeodactylum tricornutum

Frederike Stock genannt SchroerMichail SyrpasShiri Graff van CreveldSimon BackxLander BlommaertLachlan DowWillem StockEwout RuysberghBernard LepetitBenjamin BailleulKoen SabbeNorbert De KimpeAnne WillemsPeter G. KrothAssaf VardiWim VyvermanSven Mangelinckx

A1 Journal Article in ACS CHEMICAL BIOLOGY

N-acylated homoserine lactone-derived tetramic acids as algicidal compounds

Simon BackxFrederike Stock genannt SchroerShiri Graff van CreveldMichail SyrpasLander BlommaertWillem StockEwout RuysberghKoen SabbeNorbert De KimpeAnne WillemsAssaf VardiWim VyvermanSven Mangelinckx

Quorum sensing mediated interactions between bacteria and diatoms

Frederike Stock genannt SchroerWim VyvermanSven MangelinckxAnne Willems

Rearrangement of N-acylated homoserine lactones into tetramic acids as algicidal agents

Simon BackxFrederike Stock genannt SchroerShiri Graff van CreveldMichail SyrpasLander BlommaertWillem StockEwout RuysberghKoen SabbeNorbert De KimpeAnne WillemsAssaf VardiWim VyvermanSven Mangelinckx

Synthesis of racemic 2-(aminomethyl)cyclopropane-1,1-dicarboxylic acid as a new constrained γ-amino dicarboxylic acid bypassing alkyl 3-aza-2-oxobicyclo[3.1.0]hexane-1-carboxylates

Sven MangelinckxMarina KostićSimon BackxBiljana PetrovićNorbert De Kimpe

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis

Davie CappoenEveline TorfsTamara MeiresonnePieter ClaesElena SeminaFrancis HolvoetMaíra Bidart de MacedoFreya CoolsTatiana PillerAn MatheeussenKevin Van CalsterGuy CaljonPeter DelputteLouis MaesOlivier NeyrollesNorbert De KimpeSven MangelinckxPaul Cos

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2018

Reactivity of N-(3-hydroxyacyl)amino acids and influence of their corresponding homoserine lactones on cyclic lipopeptide production

Ewout RuysberghSven MangelinckxNorbert De KimpeChristian Stevens

Stereoselective synthesis of 1-amino-2-azidocyclopropanecarboxylic acid derivatives

Sven MangelinckxSietske PeetersNorbert De Kimpe

A1 Journal Article in LETTERS IN ORGANIC CHEMISTRY

2017

Bio-fouling in closed photobioreactor systems during microalgae cultivation as consequence of its associated microbiome

Javier Giraldo BritoLien RoefAnne WillemsSven MangelinckxWim VyvermanM Michiels

CHEMICAL COMMUNICATION ON A MICROSCALE - DISCOVERING ADDITIONAL ROLES OF N-ACYL HOMOSERINE LACTONES IN DIATOM BACTERIA INTERACTIONS

Frederike Stock genannt SchroerGraff S. van CreveldMichail SyrpasB. PhilippAnne WillemsSven MangelinckxWim Vyverman

Detection and toxicity evaluation of pyrrolizidine alkaloids in medicinal plants Gynura bicolor and Gynura divaricata collected from different Chinese locations

Jian ChenHan LuLian-Xiang FangWei-Lin LiLuc VerschaeveZheng-Tao WangNorbert De KimpeSven Mangelinckx

A1 Journal Article in CHEMISTRY & BIODIVERSITY

In vitro celecoxib supplementation impacts the functional capacities of the gut microbiota

Emma Hernandez SanabriaEvelien HeiremansMarta Calatayud ArroyoBart RomanSven MangelinckxLaurent LeclercqJan SnoeysTom Van de Wiele

Insecticidal activity of plant-derived extracts against different economically important pest insects

Saira KhanNji Tizi Clauvis TaningEli BonneureSven MangelinckxGuy SmaggheMohammad Maroof Shah

A1 Journal Article in PHYTOPARASITICA

Synthesis and anti(myco)bacterial activity of novel 5,5-diphenylpyrrolidine N-aroylthiourea derivatives and a functionalized hexahydro-1H-pyrrolo[1,2-c]imidazole

Duygu ErşenMahmut ÜlgerSven MangelinckxMüge GemiliErtan ŞahinYahya Nural

A1 Journal Article in MEDICINAL CHEMISTRY RESEARCH

Synthesis of 1,4-oxazepane-2,5-diones via cyclization of rotationally restricted amino acid precursors and structural reassignment of serratin

Ewout RuysberghKristof Van HeckeChristian StevensNorbert De KimpeSven Mangelinckx

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

2016

Olfactory attraction of Drosophila suzukii by symbiotic acetic acid bacteria

Fabio MazzettoElena GonellaElena CrottiVioletta VacchiniMichail SyrpasMarianna PontiniSven MangelinckxDaniele DaffonchioAlberto Alma

A1 Journal Article in JOURNAL OF PEST SCIENCE

Selective elaboration of aminodiols towards small ring α- and β-amino acid derivatives that incorporate an aziridine, azetidine, or epoxide scaffold

Elena SeminaAsta ŽukauskaitėAlgirdas ŠačkusNorbert De KimpeSven Mangelinckx

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Stable carbon isotope analyses of natural steroid hormones to determine their abuse in cattle

Geert JanssensSven MangelinckxNorbert De KimpeBruno Le Bizec

Synthesis and analysis of stable isotope-labelled N-acyl homoserine lactones

Ewout RuysberghChristian StevensNorbert De KimpeSven Mangelinckx

A1 Journal Article in RSC ADVANCES

Synthesis of new cyclic and acyclic biologically relevant amino acid derivatives

Elena SeminaSven MangelinckxNorbert De Kimpe

Synthesis of pyrido-annelated diazepines, oxazepines and thiazepines

Koen MuylaertMartyna JatczakSven MangelinckxChristian Stevens

A1 Journal Article in CURRENT MEDICINAL CHEMISTRY

The use of gas chromatography-mass spectrometry/combustion/isotope ratio mass spectrometry to demonstrate progesterone treatment in bovines

Geert JanssensSven MangelinckxDirk CourtheynNorbert De KimpeBert MatthijsBruno Le Bizec

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

2015

Asymmetric synthesis of δ-chloro-β-amino-N-sulfinyl imidates as versatile chiral building blocks for the synthesis of 2,3-disubstituted piperidines

Elena SeminaFilip ColpaertKristof Van HeckeNorbert De KimpeSven Mangelinckx

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Characterization of volatile compounds from three Cymbopogon species and Eucalyptus citriodora from Benin and their insecticidal activities against Tribolium castaneum

Annick BossouEdwige AhoussiEwout RuysberghAn AdamsGuy SmaggheNorbert De KimpeFélicien AvlessiDominique CK SohounhloueSven Mangelinckx

A1 Journal Article in INDUSTRIAL CROPS AND PRODUCTS

Natural flavonoids as potential herbal medication for the treatment of diabetes mellitus and its complications

Jian ChenSven MangelinckxAn AdamsZheng-tao WangWei-lin LiNorbert De Kimpe

A1 Journal Article in NATURAL PRODUCT COMMUNICATIONS

Occurrence and synthesis of bacterial metabolites in the marine environment and study of their chemical interactions with diatoms

Michail SyrpasNorbert De KimpeSven Mangelinckx

Profiling and elucidation of the phenolic compounds in the aerial parts of Gynura bicolor and G. divaricata collected from different Chinese origins

Jian ChenSven MangelinckxHan LuZheng-Tao WangWei-Lin LiNorbert De Kimpe

A1 Journal Article in CHEMISTRY & BIODIVERSITY

Simultaneous detection of androgen and estrogen abuse in breeding animals by gas chromatography-mass spectrometry/combustion/isotope ratio mass spectrometry (GC-MS/C/IRMS) evaluated against alternative methods

Geert JanssensSven MangelinckxDirk CourtheynNorbert De KimpeBert MatthijsBruno Le Bizec

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Straightforward synthesis of functionalized furo[3,4-d] pyrimidine-2,4-diones

Laurens De CoenMartyna JatczakKoen MuylaertSven MangelinckxChristian Stevens

A1 Journal Article in SYNTHESIS-STUTTGART

Synthesis and biological evaluation of naturally and non-naturally occurring halogenated analogues of N-acyl homoserine lactones as quorum sensing modulators

Michail SyrpasEwout RuysberghLander BlommaertBart VanelslanderKoen SabbeWim VyvermanChristian StevensNorbert De KimpeSven Mangelinckx

Synthesis of 2-fluoro-1,4-benzoxazines and 2-fluoro-1,4-benzoxazepin-5-ones by exploring the nucleophilic vinylic substitution (SNV) reaction of gem-difluoroenamides

Tamara MeiresonneGuido VerniestNorbert De KimpeSven Mangelinckx

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Synthesis of pyrido-annelated seven-membered N-containing heterocycles

Koen MuylaertMartyna JatczakSven MangelinckxChristian Stevens

A1 Journal Article in CURRENT MEDICINAL CHEMISTRY

Synthesis of strained cyclic amino acid derivatives and fluorinated heterocyclic compounds

Tamara MeiresonneSven MangelinckxNorbert De Kimpe

cis-Cyclopropylamines as mechanism-based inhibitors of monoamine oxidases

Thomas MalcomsonKemal YelekciMaria Teresa BorrelloA GanesanElena SeminaNorbert De KimpeSven MangelinckxRona R Ramsay

A1 Journal Article in FEBS JOURNAL

2014

Asymmetric synthesis of chloroisothreonine derivatives via syn-stereoselective Mannich-type additions across N-sulfinyl-α-chloroimines

Gert CallebautFilip ColpaertMelinda NonnLoránd KissReijo SillanpääKarl W TörnroosFerenc FülöpNorbert De KimpeSven Mangelinckx

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Caffeoylquinic acid derivatives isolated from the aerial parts of Gynura divaricata and their yeast α-glucosidase and PTP1B inhibitory activity

Jian ChenSven MangelinckxLi MaZhengtao WangWeilin LiNorbert De Kimpe

A1 Journal Article in FITOTERAPIA

Chemical study and biological activities (insecticide and antiplasmodial) of plant extracts from Benin

Annick BossouFélicien AvlessiNorbert De KimpeSven Mangelinckx

Discovery and biological evaluation of novel heterocyclic antitubercular drug candidates

Davie CappoenNorbert De KimpeKris HuygenSven Mangelinckx

Haloperoxidase mediated quorum quenching by Nitzschia cf pellucida: study of the metabolization of N-acyl homoserine lactones by a benthic diatom

Michail SyrpasEwout RuysberghLander BlommaertBart VanelslanderKoen SabbeWim VyvermanNorbert De KimpeSven Mangelinckx

A1 Journal Article in MARINE DRUGS

Stereoselective synthesis of 3-functionalized 2-arylpiperidines using N-tert-butanesulfinyl δ-chloro imidates

Elena SeminaFilip ColpaertKristof Van HeckeNorbert De KimpeSven Mangelinckx

Straightforward synthesis of furo[3,4-d]pyrimidine-2,4-diones

Laurens De CoenMartyna JatczakKoen MuylaertSven MangelinckxChristian Stevens

Synthesis and biological evaluation of novel N-α-haloacylated homoserine lactones as quorum sensing modulators

Michail SyrpasEwout RuysberghChristian StevensNorbert De KimpeSven Mangelinckx

A1 Journal Article in BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and conformational study of model peptides containing N-substituted 3-aminoazetidine-3-carboxylic acids

Asta ŽukauskaitėAlessandro MorettoCristina PeggionMarta De ZottiAlgirdas SačkusFernando FormaggioNorbert De KimpeSven Mangelinckx

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and early ADME evaluation of a novel scaffold, tetrahydro-6H-pyrido[3,2-b]azepin-6-one

Koen MuylaertMartyna JatczakBenjamin WuytsLaurens De CoenKristof Van HeckeHans LoonesJanneke KeeminkDaniel Garcia JimenezSven MangelinckxPieter AnnaertChristian Stevens

A1 Journal Article in SYNLETT

Synthesis and reactivity of 2-(carboxymethyl)aziridine derivatives

Gert CallebautTamara MeiresonneNorbert De KimpeSven Mangelinckx

A1 Journal Article in CHEMICAL REVIEWS

Synthesis of 2-carboxyethyl- and 2-alkenylaziridine derivatives and their transformation into novel heterocyclic and carbocyclic compounds

Stijn De BrabandereSven MangelinckxNorbert De Kimpe

Synthesis of a novel scaffold, 4-trifluoromethyl-tetrahydro-6H-pyrido[3,2-b]azepin-6-one

Koen MuylaertMartyna JatczakBenjamin WuytsLaurens M De CoenHans LoonesJanneke KeeminkDaniel Garcia JimenezSven MangelinckxKristof Van HeckePieter AnnaertChristian Stevens

Synthesis of alkyl 3-chloroazetidine-3-carboxylates via regioselective ring transformation of alkyl 2-(bromomethyl)aziridine-2-carboxylates

Asta ŽukauskaitėSven MangelinckxAlgirdas SackusNorbert De Kimpe

A1 Journal Article in HETEROCYCLES

Synthesis of γ,δ-aziridino α-amino acid derivatives and their stereoselective ring transformation to 2-(aminomethyl)-1-aminocyclopropanecarboxylic acid derivatives

Stijn De BrabandereSven MangelinckxSantosh KadamYahya NuralKoen AugustynsPieter Van der VekenKarl W TornroosNorbert De Kimpe

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The Cu(OTf)2 catalysed microwave assisted synthesis of a new scaffold, 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-one

Koen MuylaertSven MangelinckxMartyna JatczakLaurens De CoenKristof Van HeckeChristian Stevens

A1 Journal Article in ARKIVOC

2013

Application of gas chromatography-mass spectrometry/combustion/isotope ratio mass spectrometry (GC-MS/C/IRMS) to detect the abuse of 17β-estradiol in cattle

Geert JanssensSven MangelinckxDirk CourtheynStéphanie PrévostGeert De PoorterNorbert De KimpeBruno Le Bizec

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chemical composition and insecticidal activity of plant essential oils from Benin against Anopheles gambiae (Giles)

Annick BossouSven MangelinckxHounnankpon YedomonhanPelagie M BokoMartin C AkogbetoNorbert De KimpeFelicien AvlessiDominique CK Sohounhloue

A1 Journal Article in PARASITES & VECTORS

Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry

Gert CallebautSven MangelinckxNorbert De Kimpe

Synthesis and biological evaluation of N-alpha-haloacylated homoserine lactones

Michail SyrpasEwout RuysberghSven MangelinckxNorbert De Kimpe

Synthesis of 1,5-diazaspiro[2.3]hexanes, a novel diazaspirocyclic system

Asta ŽukauskaitėSven MangelinckxGert CallebautClarence WybonAlgirdas ŠačkusNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Synthesis of cis-2-alkoxycyclopropylamines via intramolecular cyclization of 2-azaallylic anions derived from alkoxybrominated N-(arylidene)-2-methyl-2-propenylamines

Sven MangelinckxSantosh KadamElena SeminaGert CallebautFilip ColpaertDirk De SmaeleNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Use of isotope ratio mass spectrometry to differentiate between endogenous steroids and synthetic homologues in cattle: a review

Geert JanssensDirk CourtheynSven MangelinckxStephanie PrevostEmmanuelle BichonFabrice MonteauGeert De PoorterNorbert De KimpeBruno Le Bizec

A1 Journal Article in ANALYTICA CHIMICA ACTA

2012

Absorption, translocation and metabolism of metamitron in Chenopodium album

Jonas AperEls MechantBaruch RubinArne HeyerickGert CallebautSven MangelinckxDieter DeforceNorbert De KimpeRobert BulckeDirk Reheul

A1 Journal Article in PEST MANAGEMENT SCIENCE

Asymmetric synthesis of α,β-diamino acid derivatives with an aziridine-, azetidine- and γ-lactone-skeleton via Mannich-type additions across α-chloro-N-sulfinylimines

Gert CallebautSven MangelinckxLorand KissReijo SillanpaaFerenc FulopNorbert De Kimpe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines

Gert CallebautSven MangelinckxPieter Van der VekenKarl W TornroosKoen AugustynsNorbert De Kimpe

A1 Journal Article in BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY

Chemical constituents from the aerial parts of Gynura bicolor

Jian ChenSven MangelinckxAn AdamsWei-lin LiZT WangNorbert De Kimpe

A1 Journal Article in NATURAL PRODUCT COMMUNICATIONS

Diastereoselective Aldol reaction of Zincated 3-Chloro-3-methyl-1-azaallylic anions as key step in the synthesis of 1,2,3,4-Tetrasubstituted 3-Chloroazetidines

Sven MangelinckxBart De SterckFilip ColpaertSaron CatakJan JacobsStijn RooryckMichel WaroquierVeronique Van SpeybroeckNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Facile synthesis of spiro[benzo[e]indole-2,2 '-piperidine] derivatives and their transformation to novel fluorescent scaffolds

Vida BuinauskaiteVytas MartynaitisSven MangelinckxGediminas KreizaNorbert De KimpeAlgirdas Šačkus

A1 Journal Article in TETRAHEDRON

Investigation of the volatile constituents of different Gynura species from two Chinese origins by SPME/GC-MS

Jian ChenAn AdamsSven MangelinckxBing-ru RenWei-lin LiZheng-tao WangNorbert De Kimpe

A1 Journal Article in NATURAL PRODUCT COMMUNICATIONS

Isolation and characterization of the chemical constituents from Gynura bicolor and G. divaricata

Jian ChenSven MangelinckxAn AdamsWL LiZT WangNorbert De Kimpe

Rearrangement of N-tert-butanesulfinyl α-halo imines with alkoxides to N-tert-butanesulfinyl 2-amino acetals as precursors of N-protected and N-unprotected α-amino carbonyl compounds

Filip ColpaertSven MangelinckxBram DenolfNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Stereoselective synthesis of both enantiomers of trans-2-(diphenylmethylideneamino)cyclopropanecarboxylic acid using a chiral pool approach and their incorporation in dipeptides

Tamara MeiresonneSven MangelinckxNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

2011

Asymmetric synthesis of alpha-Chloro-beta-amino-N-sulfinyl imidates as chiral building blocks

Filip ColpaertSven MangelinckxStijn De BrabandereNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Asymmetric synthesis of chiral N-sulfinyl 3-alkyl- and 3-arylpiperidines by alpha-Alkylation of N-sulfinyl imidates with 1-Chloro-3-iodopropane

Filip ColpaertSven MangelinckxNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

New general synthesis of alpha-alkoxyketones via alpha'-alkylation, alpha-alkylation and alpha,alpha'-dialkylation of alpha-alkoxyketimines

Filip ColpaertSven MangelinckxMaria Teresa RocchettiNorbert De Kimpe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and reactions of 1-hydroxy-9,9a-dihydro-1H-imidazo[1,2-a]indol-2(3H)-ones

Vytas MartynaitisRasa SteponaviciuteSonata KrikstolaityteJoana SolovjovaSven MangelinckxNorbert De KimpeWolfgang HolzerAlgirdas Sackus

A1 Journal Article in TETRAHEDRON

Synthesis of 1,2,3-trisubstituted pyrrolidines and 2,3-disubstituted tetrahydrofurans via diastereoselective reductive cyclization of γ-chloroimines and γ-chloroketones

Naga Venkata Sastry MudigantiSven MangelinckxBart LucasNorbert De Kimpe

A1 Journal Article in SYNLETT

Synthesis of 3-aryl-3-pyrrolines and 3-arylpyrroles via spontaneous rearrangement of N-sulfinyl 2-aryl-2-vinylaziridines

Erika LeemansFilip ColpaertSven MangelinckxStijn De BrabandereBram DenolfNorbert De Kimpe

A1 Journal Article in SYNLETT

Synthesis of new functionalized aziridine-2-and azetidine-3-carboxylic acid derivatives of potential interest for biological and foldameric applications

Asta ŽukauskaitėSven MangelinckxVida BuinauskaiteAlgirdas SackusNorbert De Kimpe

A1 Journal Article in AMINO ACIDS

Synthesis of novel β-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure

Tamara MeiresonneSven MangelinckxNorbert De Kimpe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Transformations of 3-aryl-2-chloro-2-imidoylaziridines: novel entries to 4-chloro-2,5-diaryl-1H-imidazoles and 2-Chloro-2-acylaziridines

Filip ColpaertSven MangelinckxNicola GiubellinaNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

2010

Asymmetric synthesis of 2-arylpyrrolidines starting from y-chloro N-(tert-butanesulfinyl)ketimines

Erika LeemansSven MangelinckxNorbert De Kimpe

A1 Journal Article in CHEMICAL COMMUNICATIONS

Asymmetric synthesis of new chiral N-sulfinyl 2,2-disubstituted aziridines by Grignard additions across alpha-chloro N-sulfinyl ketimines

Filip ColpaertSven MangelinckxErika LeemansBram DenolfNorbert De Kimpe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric synthesis of new chiral β-amino acid derivatives by Mannich-type reactions of chiral N-sulfinyl imidates with N-tosyl aldimines

Filip ColpaertSven MangelinckxNorbert De Kimpe

A1 Journal Article in ORGANIC LETTERS

Diastereoselective synthesis of 6-functionalized 4-aryl-1,3-oxazinan-2-ones and their application in the synthesis of 3-aryl-1,3-aminoalcohols and 6-arylpiperidine-2,4-diones

Sven MangelinckxYahya NuralH Ali DondasBram DenolfReijo SillanpääNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

2009

A theoretical study on the solvated structural properties of various metalated 3-halo-1-azaallylic anions

Bart De SterckVeronique Van SpeybroeckSven MangelinckxGuido VerniestNorbert De KimpeMichel Waroquier

A1 Journal Article in Journal of Physical Chemistry A

Asymmetric synthesis of α-alkylated N-sulfinyl imidates as new chiral building blocks

Filip ColpaertSven MangelinckxGuido VerniestNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Insight into the solvation and isomerization of 3-halo-1-azaallylic anions from ab initio metadynamics calculations and NMR experiments

Reinout DeclerckBart De SterckToon VerstraelenGuido VerniestSven MangelinckxJan JacobsNorbert De KimpeMichel WaroquierVeronique Van Speybroeck

A1 Journal Article in Chemistry - A European Journal

Novel synthesis of chiral unactivated 2-aryl-1-benzylaziridines

Erika LeemansSven MangelinckxNorbert De Kimpe

A1 Journal Article in SYNLETT

Synthesis and Ring Opening of Alkaloid-Type Compounds with a Novel Indolo[2,3-c][2]benzazepine Skeleton

Joana SolovjovaVitas MartynaitisSven MangelinckxWolgang HolzerNorbert De KimpeAlgirdas Sackus

A1 Journal Article in SYNLETT

Synthesis and reactions of 1-amino-1,5,6,10b-tetrahydroimidazo[2,1-a]isoquinolin-2(3H)-ones

Joana SolovjovaVytas MartynaitisWolfgang HolzerSven MangelinckxNorbert De KimpeAlgirdas Šačkus

A1 Journal Article in ARKIVOC

Synthesis and reactivity of 3-haloazetidines and 3-sulfonyloxyazetidines: a review

Willem Van BrabandtSven MangelinckxMatthias D'hoogheBerten Van DriesscheNorbert De Kimpe

A1 Journal Article in CURRENT ORGANIC CHEMISTRY

Synthesis of 2-[(arylmethylene)amino]cyclopropanecarbonitriles via a two-step ring transformation of 2-(cyanomethyl)aziridines

Sven MangelinckxMatthias D'hoogheSietske PeetersNorbert De Kimpe

A1 Journal Article in SYNTHESIS-STUTTGART

Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells

Maria E RivieroDominick MaesRamiro VasquezMonica VermeulenSven MangelinckxJan JacobsSilvia DebenedettiCarina ShayoNorbert De KimpeCarlos Davio

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2008

2-(dichloromethylene)azetidines: Stable strained cyclic enamines

Sven MangelinckxMarc BoeykensNorbert De Kimpe

A1 Journal Article in SYNLETT

Ab initio evaluation of metalated 3-halo-1-azaallylic anions as synthetic building blocks

Bart De SterckVeronique Van SpeybroeckGuido VerniestSven MangelinckxNorbert De KimpeMichel Waroquier

Experimental and computational study of the conrotatory ring opening of various 3-chloro-2-azetines

Sven MangelinckxVeronique Van SpeybroeckPeter VansteenkisteMichel WaroquierNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Functionalized Dialkyl Cyclobutane-1,1-dicarboxylates and Alkyl 5,6-Dihydro-4H-pyran-3-carboxylates via Michael-Induced Ring Closure of delta-chloro-alpha,beta-Unsaturated Diesters and Ketoesters

Sven MangelinckxBruno VermautRoland VerhéNorbert De Kimpe

A1 Journal Article in SYNLETT

Synthesis of alkyl 2-(bromomethyl)aziridine-2-carboxylates and alkyl 3-bromoazetidine-3-carboxylates as amino acid building blocks

Sven MangelinckxAsta ZukauskaiteVida BuinauskaiteAlgirdas SackusNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

2007

An easy stereoselective access to beta,gamma-aziridino alpha-amino ester derivatives via Mannich reaction of benzophenone Imines of glycine esters with N-sulfonyl alpha-chloroaldimines

Lorand KissSven MangelinckxR SILLANPAAF FULOPNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Asymmetric synthesis of cyclopropylamines starting from N-sulfinyl alpha-chloro ketimines

Bram DenolfSven MangelinckxKW TORNROOSNorbert De Kimpe

A1 Journal Article in ORGANIC LETTERS

Convenient synthesis of trans-beta-amino carboxylic esters with an azetidine skeleton via rearrangement of beta,gamma-aziridino alpha-amino esters

Lorand KissSven MangelinckxF FULOPNorbert De Kimpe

A1 Journal Article in ORGANIC LETTERS

Straightforward synthesis of alkynyl imines via 1,2-elimination of alpha,alpha-dichloroketimines

Sven MangelinckxStijn RooryckJan JacobsNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

2006

An efficient synthesis of γ-imino- and γ-amino-β-enamino esters

Sven MangelinckxPieter Van VoorenDavid De ClerckFerenc FülöpNorbert De Kimpe

A1 Journal Article in ARKIVOC

Michael-induced ring closure to 2-azidocyclopropane-1,1-dicarboxylates and their staudinger reduction to 5-alkoxy-3-(alkoxycarbonyl)pyrrolidin-2-ones

Sven MangelinckxNorbert De Kimpe

A1 Journal Article in SYNLETT

New syntheses of beta-aminocyclopropanecarboxylic acid derivatives and study of their reactivity

Sven MangelinckxNorbert De Kimpe

Reaction of electrophilic allyl halides with amines: A reinvestigation

Sven MangelinckxD COURTHEYNRoland VerhéVeronique Van SpeybroeckMichel WaroquierNorbert De Kimpe

A1 Journal Article in SYNTHESIS-STUTTGART

Synthesis and ring transformations of 1-amino-1,2,3,9a-tetrahydroimidazo[ 1,2-a]indol-2(9H)-ones

J DUMCIUTEV MARTYNAITISW HOLZERSven MangelinckxNorbert De KimpeA SACKUS

A1 Journal Article in TETRAHEDRON

Synthesis of 1-arylmethyl-2-(cyanomethyl) aziridines and their ring transformation into methyl N-(2-cyanocyclopropyl) benzimidates

Matthias D'hoogheSven MangelinckxE PERSYNWillem Van BrabandtN KIMPE

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 2-chloro-2-imidoylaziridines via aza-darzens-type reaction of 3,3-dichloro-1-azaallylic anions and N-(arylsulfonyl) imines

Nicola GiubellinaSven MangelinckxKW TORNROOSNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Use of alpha-chlorinated N-(tert-butanesulfinyl)-imines in the synthesis of chiral aziridines

Bram DenolfSven MangelinckxKW TORNROOSNorbert De Kimpe

A1 Journal Article in ORGANIC LETTERS

2005

Synthesis and structural revision of naturally occurring ayapin derivatives

Dominick MaesS VERVISCHS DEBENEDETTIC DAVIOSven MangelinckxNicola GiubellinaNorbert De Kimpe

A1 Journal Article in TETRAHEDRON

Synthesis of N-protected beta-aminocyclopropanedicarboxylates and their ring transformation to N-benzhydryl-3-alkoxycarbonyl-4,4-dialkyl-pyrrolidin-2-ones

Sven MangelinckxNorbert De Kimpe

A1 Journal Article in SYNLETT

Synthesis of new 3,3-dimethoxyazetidine-2-carboxylic acid derivatives

Sven MangelinckxMarc BoeykensM VLIEGENJohan Van der EyckenNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

2004

1-Azaallylic anions in heterocyclic chemistry

Sven MangelinckxNicola GiubellinaNorbert De Kimpe

A1 Journal Article in CHEMICAL REVIEWS

2003

Synthesis of racemic cis-1-alkyl- and 1-aryl-2-aminocyclopropanecarboxylic esters

Sven MangelinckxNorbert De Kimpe

A1 Journal Article in TETRAHEDRON LETTERS

2002

Rearrangement of 2-aryl-3,3-dichloroazetidines: Intermediacy of 2-azetines.

Yves DejaegherSven MangelinckxNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Synthesis of substituted benzhydrylamines.

Yves DejaegherSven MangelinckxNorbert De Kimpe

A1 Journal Article in SYNLETT