Research Explorer

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Researcher

Stijn Vansteelandt

Publications & Research Data

Awards & Distinctions

316 Results

2026

Two stage least squares with time-varying instruments : an application to an evaluation of treatment intensification for type-2 diabetes

Daniel TompsettStijn VansteelandtRichard GrieveJohn RobsonManuel Gomes

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

2025

All lines is the right approach : selecting patient lines of therapy for an external comparator arm

Daniel BackenrothLaura HesterStijn Vansteelandt

A1 Journal Article in PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Cannabis use is not associated with altered levels of physical activity : evidence from the repeated cross-sectional Belgian Health Interview Survey (vol 7,22,2025)

Brent VernaillenBrecht DevleesschauwerStijn VansteelandtLydia GisleSabine DrieskensElena Damian

Cannabis use is not associated with altered levels of physical activity: evidence from the repeated cross-sectional Belgian Health Interview Survey

Brent VernaillenBrecht DevleesschauwerStijn VansteelandtLydia GisleSabine DrieskensElena Damian

A2 Journal Article in JOURNAL OF CANNABIS RESEARCH

Causal inference for vaccine trials : methods for recurrent events with dependent censoring and efficient use of external controls

Wout WaterschootStijn VansteelandtAndrea Callegaro

Causal machine learning for heterogeneous treatment effects in the presence of missing outcome data

Matthew PryceKarla Diaz-OrdazRuth H. KeoghStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Causal machine learning methods and use of cross-fitting in settings with high-dimensional confounding

Susan EllulStijn VansteelandtJohn B. CarlinMargarita Moreno-Betancur

A1 Journal Article in STATISTICS IN MEDICINE

Chasing shadows : how implausible assumptions skew our understanding of causal estimands

Stijn VansteelandtKelly Van Lancker

A1 Journal Article in STATISTICS IN BIOPHARMACEUTICAL RESEARCH

Debiased learning of the causal net benefit with censored event time data

Torben MartinussenStijn Vansteelandt

A1 Journal Article in BIOMETRIKA

Discussion of 'On the uses and abuses of regression models : a call for reform of statistical practice and teaching'

Stijn VansteelandtJohan Steen

Editorial material

Instrumental variable approaches for estimating time-varying treatment effects in comparative effectiveness research

Daniel TompsettStijn VansteelandtRichard GrieveWill DixonManuel Gomes

A1 Journal Article in BMC MEDICAL RESEARCH METHODOLOGY

Instrumental variable methods to target hypothetical estimands with longitudinal repeated measures data : application to the STEP 1 trial

Jack BowdenJesper MadsenBryan GoldmanAske Thorn IversenXiaoran LiangStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Mediation analysis of path-specific effects in randomised clinical trials with repeatedly measured mediators and outcomes

Martin LinderJesper MadsenStijn Vansteelandt

A1 Journal Article in PHARMACEUTICAL STATISTICS

Orthogonal prediction of counterfactual outcomes

Stijn VansteelandtPawel Morzywolek

A1 Journal Article in JOURNAL OF CAUSAL INFERENCE

Perceptions of ethical decision-making climate among clinicians working in European and US ICUs : differences between religious and non-religious healthcare professionals

Hanne Irene JensenHans-Henrik BülowLucas DierickxStijn VansteelandtRosanna VaschettoGábor ÉlöRuth PiersDominique Benoit

A1 Journal Article in BMC MEDICAL ETHICS

Propensity weighting plus adjustment in proportional hazards model is not doubly robust," by Erin E. Gabriel, Michael C. Sachs, Ingeborg Waernbaum, Els Goetghebeur, Paul F. Blanche, Stijn Vansteelandt, Arvid Sjölander, and Thomas Scheike( vol 80 ,10.1093/biomtc/ujae069 , 2024)

Erin E. GabrielMichael C. SachsIngeborg WaernbaumEls GoetghebeurPaul F. BlancheStijn VansteelandtArvid SjölanderThomas Scheike

Rejoinder to the discussion on 'Chasing shadows : how implausible assumptions skew our understanding of causal estimands'

Stijn VansteelandtKelly Van Lancker

Editorial material

The importance of sensitivity analyses for the MR Steiger approach

Sharon M. LutzKirsten VoorhiesJohn E. HokansonStijn VansteelandtChristoph Lange

A1 Journal Article in GENETIC EPIDEMIOLOGY

Towards efficient and interpretable assumption-lean generalized linear modeling of continuous exposure effects

Stijn Vansteelandt

A1 Journal Article in BIOMETRICS

Variable importance measures for heterogeneous treatment effects

Oliver J. HinesKarla Diaz-OrdazStijn Vansteelandt

A1 Journal Article in BIOMETRICS

2024

A causal inference approach to mediation analysis in vitreomacular traction : how much does traction resolution mediate functional outcomes?

Benedicte LescrauwaetStijn VansteelandtTimothy L. JacksonSriniVas R. SaddaLuc Duchateau

A2 Journal Article in JOURNAL OF MARKET ACCESS & HEALTH POLICY

Adjusting for time-varying treatment switches in randomized clinical trials : the danger of extrapolation and how to address it

Hege MichielsAn VandeboschStijn Vansteelandt

A1 Journal Article in STATISTICS IN BIOPHARMACEUTICAL RESEARCH

AI en nieuwe vormen van klinische studies : gladjes naar evidentie of evidentie op glad ijs?

Johan SteenStijn Vansteelandt

Bookchapter in Geneeskunde in tijden van AI : handvatten voor vandaag en morgen

Assumption-lean cox regression

Stijn VansteelandtOliver DukesKelly Van LanckerTorben Martinussen

A1 Journal Article in JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Counterfactual mediation analysis with a latent class exposure

Gemma HammertonJon HeronKatie LewisKate TillingStijn Vansteelandt

A1 Journal Article in MULTIVARIATE BEHAVIORAL RESEARCH

Dealing with time‐dependent exposures and confounding when defining and estimating attributable fractions : revisiting estimands and estimators

Johan SteenPawel MorzywolekWim Van BiesenJohan DecruyenaereStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Debiasing synthetic data generated by deep generative models

Alexander DecruyenaereHeidelinde DehaenePaloma RabaeyJohan DecruyenaereChristiaan PoletThomas DemeesterStijn Vansteelandt

Discussion on : 'Simple or complex statistical models : non-traditional regression models with intuitive interpretations' by Gillian Z. Heller

Jan BeyersmannGuadalupe Gómez MelisThomas KneibGeert MolenberghsVito MuggeoStijn VansteelandtGillian Z. Heller

A1 Journal Article in STATISTICAL MODELLING

Inference failure with synthetic arms : empirical application to phase III oncology trials

Alexander DecruyenaereHeidelinde DehaenePaloma RabaeyCharles PoletJohan DecruyenaereToon DemeesterStijn VansteelandtSylvie Rottey

Inverse probability of treatment weighting with generalized linear outcome models for doubly robust estimation

Erin E. GabrielMichael C. SachsTorben MartinussenIngeborg WaernbaumEls GoetghebeurStijn VansteelandtArvid Sjölander

A1 Journal Article in STATISTICS IN MEDICINE

On doubly robust inference for double machine learning in semiparametric regression

Oliver DukesStijn VansteelandtDavid Whitney

A1 Journal Article in JOURNAL OF MACHINE LEARNING RESEARCH

Outcomes of critically ill patients with and without concordant perceptions of excessive care : a comparison between more religious and less religious ICUs

Lucas DierickxHanne Irene JensenHans-Henrik BülowStijn VansteelandtRosanna VaschettoGábor ÉlőRuth PiersDominique Benoit

Propensity weighting plus adjustment in proportional hazards model is not doubly robust

Erin E. GabrielMichael C. SachsIngeborg WaernbaumEls GoetghebeurPaul F. BlancheStijn VansteelandtArvid SjölanderThomas Scheike

A1 Journal Article in BIOMETRICS

Socioeconomic and mental health factors : key predictors of revictimization

Elizaveta FomenkoInes KeygnaertStijn Vansteelandt

Structural mean models for instrumented difference-in-differences

Tat-Thang VoTing YeAshkan ErtefaieSamrat RoyJames FlorySean HennessyStijn VansteelandtDylan S. Small

A1 Journal Article in ELECTRONIC JOURNAL OF STATISTICS

The incremental healthcare cost associated with cancer in Belgium : a registry‐based data analysis

Vanessa GorassoStefanie VandevijvereJohan Van Der HeydenIngrid PelgrimsHenk HilderinkWilma NusselderClaire DemouryMasja SchmidtStijn VansteelandtDelphine De Smedt et al.

A1 Journal Article in CANCER MEDICINE

The potential impact fraction of population weight reduction scenarios on non-communicable diseases in Belgium : application of the g-computation approach

Ingrid PelgrimsBrecht DevleesschauwerStefanie VandevijvereEva M. De ClercqJohan van der HeydenStijn Vansteelandt

A1 Journal Article in BMC MEDICAL RESEARCH METHODOLOGY

The real deal behind the artificial appeal : inferential utility of tabular synthetic data

Alexander DecruyenaereHeidelinde DehaenePaloma RabaeyChristiaan PoletJohan DecruyenaereStijn VansteelandtThomas Demeester

Why synthetic discoveries are not only a problem of differentially private synthetic data

Heidelinde DehaeneAlexander DecruyenaereChristiaan PoletJohan DecruyenaerePaloma RabaeyThomas DemeesterStijn Vansteelandt

A1 Journal Article in METHODS OF INFORMATION IN MEDICINE

2023

An application of causal inference in vitreomacular traction : how does the effect of ocriplasmin on functional and patient-reported outcomes occur

Benedicte LescrauwaetLuc DuchateauStijn VansteelandtSriniVas SaddaTimothy Jackson

Assessing the benefits of hypothetical air pollution reduction interventions on stroke in Belgium

Ingrid PelgrimsBrecht DevleesschauwerS. VandevijvereE. M. De ClercqVanessa GorassoJ. Van der HeydenStijn Vansteelandt

Causal estimands and estimation for randomized clinical trials with intercurrent events : addressing extrapolation

Hege MichielsStijn VansteelandtAn Vandebosch

Causal inference in survival analysis using longitudinal observational data : sequential trials and marginal structural models

Ruth H. KeoghJon Michael GranShaun R. SeamanGwyneth DaviesStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Causal inference methods to optimize clinical decision-making in treatment initiation based on routinely collected data

Pawel MorzywolekStijn VansteelandtWim Van BiesenJohan Steen

Coaching doctors to improve ethical decision-making in adult hospitalised patients potentially receiving excessive treatment : study protocol for a stepped wedge cluster randomised controlled trial

Dominique BenoitStijn VanheuleFrank ManesseFrederik AnseelGeert De SoeteKatrijn GoethalsAn LievrouwStijn VansteelandtErik De HaanRuth Piers et al.

A1 Journal Article in PLOS ONE

Comment on 'Estimands and their estimators for clinical trials impacted by the COVID-19 pandemic : a report from the NISS Ingram Olkin Forum Series on unplanned clinical trial disruptions'

Stijn Vansteelandt

Editorial material

Contribution of air pollution and overweight to non-communicable diseases in Belgium : addressing the limitations of observational studies

Ingrid PelgrimsStijn VansteelandtEva De ClercqBrecht Devleesschauwer

Ensuring valid inference for cox hazard ratios after variable selection

Kelly Van LanckerOliver DukesStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Instrumental variable estimation of the causal hazard ratio

Linbo WangEric Tchetgen TchetgenTorben MartinussenStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Jialiang LiStijn Vansteelandt

Editorial material

Rejoinder to discussions on 'Instrumental variable estimation of the causal hazard ratio'

Linbo WangEric Tchetgen TchetgenTorben MartinussenStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Semiparametric estimation of probabilistic index models : efficiency and bias

Karel VermeulenJan De NeveGustavo AmorimOlivier ThasStijn Vansteelandt

A1 Journal Article in STATISTICA SINICA

Synthetic data : can we trust statistical estimators?

Alexander DecruyenaereHeidelinde DehaenePaloma RabaeyChristiaan PoletJohan DecruyenaereStijn VansteelandtThomas Demeester

The health and economic burden of musculoskeletal disorders in Belgium from 2013 to 2018

Vanessa GorassoJohan Van Der HeydenRobby De PauwIngrid PelgrimsEva M. De ClercqKarin De RidderStefanie VandevijvereStijn VansteelandtBert VaesDelphine De Smedt et al.

A1 Journal Article in POPULATION HEALTH METRICS

The role of loneliness on hearing ability and dementia : a novel mediation approach

Ruth A. HackettVõ Tẩt ThẳngStijn VansteelandtHilary Davies-Kershaw

A1 Journal Article in JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Understanding the effects of a complex psychological intervention on symptoms of depression in Goa, India : findings from a causal mediation analysis

Nadine SewardStijn VansteelandtDario Moreno-AgostinoVikram PatelRicardo Araya

A1 Journal Article in BRITISH JOURNAL OF PSYCHIATRY

Using random-forest multiple imputation to address bias of self-reported anthropometric measures, hypertension and hypercholesterolemia in the Belgian health interview survey

Ingrid PelgrimsBrecht DevleesschauwerStefanie VandevijvereEva M. De ClercqStijn VansteelandtVanessa GorassoJohan Van Der Heyden

A1 Journal Article in BMC MEDICAL RESEARCH METHODOLOGY

2022

A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables

Julian HeckerDmitry ProkopenkoMatthew MollSanghun LeeWonji KimDandi QiaoKirsten VoorhiesWoori KimStijn VansteelandtBrian D. Hobbs et al.

A1 Journal Article in PLOS GENETICS

A statistical test to reject the structural interpretation of a latent factor model

Tyler J. VanderWeeleStijn Vansteelandt

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Assumption‐lean inference for generalised linear model parameters

Stijn VansteelandtOliver Dukes

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Authors' reply to the discussion of ‘Assumption‐lean inference for generalised linear model parameters’ by Vansteelandt and Dukes

Stijn VansteelandtOliver Dukes

Editorial material

Challenges in systematic reviews and meta-analyses of mediation analyses

Võ Tẩt ThẳngStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Demystifying statistical learning based on efficient influence functions

Oliver HinesOliver DukesKarla Diaz-OrdazStijn Vansteelandt

A1 Journal Article in AMERICAN STATISTICIAN

Direct and indirect costs attributable to musculoskeletal disorders in Belgium

Vanessa GorassoJ. Van derHeydenRobby De PauwIngrid PelgrimsK. De RidderS. VandevijvereStijn VansteelandtB. VaesDelphine De SmedtBrecht Devleesschauwer

Disentangling indirect effects through multiple mediators without assuming any causal structure among the mediators

Wen Wei LohBeatrijs MoerkerkeTom LoeysStijn Vansteelandt

A1 Journal Article in PSYCHOLOGICAL METHODS

Estimation and interpretation of vaccine efficacy in COVID-19 randomized clinical trials

Hege MichielsAn VandeboschStijn Vansteelandt

A2 Journal Article in STATISTICAL COMMUNICATIONS IN INFECTIOUS DISEASES

Health care costs and lost productivity costs related to excess weight in Belgium

Vanessa GorassoIsabelle MoyersoenJohan Van der HeydenKarin De RidderStefanie VandevijvereStijn VansteelandtDelphine De SmedtBrecht Devleesschauwer

A1 Journal Article in BMC PUBLIC HEALTH

How do psychologically based interventions for chronic musculoskeletal pain work? A systematic review and meta-analysis of specific moderators and mediators of treatment

Carlos Murillo EzcurraVõ Tẩt ThẳngStijn VansteelandtLauren E. HarrisonBarbara CagnieIris CoppietersMarjolein ChysInge TimmersMira Meeus

A1 Journal Article in CLINICAL PSYCHOLOGY REVIEW

Longitudinal mediation analysis of time-to-event endpoints in the presence of competing risks

Võ Tẩt ThẳngHilary Davies-KershawRuth HackettStijn Vansteelandt

A1 Journal Article in LIFETIME DATA ANALYSIS

Nonlinear mediation analysis with high‐dimensional mediators whose causal structure is unknown

Wen Wei LohBeatrijs MoerkerkeTom LoeysStijn Vansteelandt

A1 Journal Article in BIOMETRICS

On estimation and cross–validation of dynamic treatment regimes with competing risks

Pawel MorzywolekJohan SteenWim Van BiesenJohan DecruyenaereStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Quality assessment practice in systematic reviews of mediation studies : results from an overview of systematic reviews

Võ Tẩt ThẳngAidan CashinCecilia SuperchiPham Hien Trang TuThanh Binh NguyenIsabelle BoutronDavid MacKinnonTyler VanderweeleHopin LeeStijn Vansteelandt

A1 Journal Article in JOURNAL OF CLINICAL EPIDEMIOLOGY

Selection bias when inferring the effect direction in Mendelian randomization

Sharon M. LutzKirsten VoorhiesAnn C. WuJohn HokansonStijn VansteelandtChristoph Lange

A1 Journal Article in GENETIC EPIDEMIOLOGY

Target trial emulation on timing of start of renal replacement therapy in acute kidney injury : lessons learned

Johan SteenStijn VansteelandtJohan DecruyenaereWim Van Biesen

The burden of musculoskeletal disorders in Belgium : a national population-based study

Vanessa GorassoJ. Van der HeydenRobby De PauwIngrid PelgrimsK. De RidderS. VandevijvereStijn VansteelandtB. VaesDelphine De SmedtBrecht Devleesschauwer

The influence of unmeasured confounding on the MR Steiger approach

Sharon M. LutzKirsten VoorhiesAnn Chen WuJohn HokansonStijn VansteelandtChristoph Lange

A1 Journal Article in GENETIC EPIDEMIOLOGY

Timing of dialysis in acute kidney injury using routinely collected data and dynamic treatment regimes

Pawel MorzywolekJohan SteenStijn VansteelandtJohan DecruyenaereSigrid SterckxWim Van Biesen

A1 Journal Article in CRITICAL CARE

Using routinely collected data to define the optimal timing to initiate renal replacement therapy in AKI patients

Pawel MorzywolekJohan SteenStijn VansteelandtJohan DecruyenaereWim Van Biesen

2021

A guideline for reporting mediation analyses of randomized trials and observational studies : the AGReMA statement

Hopin LeeAidan G. CashinSarah E. LambSally HopewellStijn VansteelandtTyler J. VanderWeeleDavid P. MacKinnonGemma MansellGary S. CollinsRobert M. Golub et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A novel estimand to adjust for rescue treatment in randomized clinical trials

Hege MichielsCristina SottoAn VandeboschStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Attributable mortality of ventilator-associated pneumonia : replicating findings, revisiting methods

Johan SteenStijn VansteelandtLiesbet De BusPieter DepuydtBram GadeyneDominique BenoitJohan Decruyenaere

A1 Journal Article in ANNALS OF THE AMERICAN THORACIC SOCIETY

Causal inference concepts applied to three observational studies in the context of vaccine development : from theory to practice

Emilia GvozdenovićLucio MalvisiElisa CinconzeStijn VansteelandtPhoebe NakanwagiEmmanuel ArisDominique Rosillon

A1 Journal Article in BMC MEDICAL RESEARCH METHODOLOGY

Caution against examining the role of reverse causality in Mendelian Randomization

Sharon M. LutzAnn Chen WuJohn E. HokansonStijn VansteelandtChristoph Lange

A1 Journal Article in GENETIC EPIDEMIOLOGY

Confounder selection strategies targeting stable treatment effect estimators

Wen Wei LohStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Data-adaptive methods for high-dimensional mediation analysis : application to a randomised trial of tuberculosis vaccination

Margarita Moreno-BetancurNicole L. MessinaKaya GardinerNigel CurtisStijn Vansteelandt

Discussion of Kallus and Mo, Qi, and Liu : new objectives for policy learning

Stijn VansteelandtOliver Dukes

Editorial material

Efficient, doubly robust estimation of the effect of dose switching for switchers in a randomized clinical trial

Kelly Van LanckerAn VandeboschStijn Vansteelandt

A1 Journal Article in BIOMETRICAL JOURNAL

How much can we remedy very low learning levels in rural parts of low-income countries? Impact and generalizability of a multi-pronged para-teacher intervention from a cluster-randomized trial in the Gambia

Alex EbleChris FrostAlpha CamaraBaboucarr BouyMomodou BahMaitri SivaramanPei-Tseng Jenny HsiehChitra JayantyTony BradyPiotr Gawron et al.

A1 Journal Article in JOURNAL OF DEVELOPMENT ECONOMICS

Inference for treatment effect parameters in potentially misspecified high-dimensional models

Oliver DukesStijn Vansteelandt

A1 Journal Article in BIOMETRIKA

Optimizing treatment effect estimation in randomized trials by leveraging baseline covariates and early read-outs

Kelly Van LanckerStijn VansteelandtAn Vandebosch

Prediction of hospital bed capacity during the COVID-19 pandemic

Mieke DeschepperKristof EecklooSimon MalfaitDominique BenoitSteven CallensStijn Vansteelandt

A1 Journal Article in BMC HEALTH SERVICES RESEARCH

Principled selection of baseline covariates to account for censoring in randomized trials with a survival endpoint

Kelly Van LanckerOliver DukesStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Robust inference for mediated effects in partially linear models

Oliver HinesStijn VansteelandtKarla Diaz-Ordaz

A1 Journal Article in PSYCHOMETRIKA

Simulating longitudinal data from marginal structural models using the additive hazard model

Ruth H. KeoghShaun R. SeamanJon Michael GranStijn Vansteelandt

A1 Journal Article in BIOMETRICAL JOURNAL

Stable inverse probability weighting estimation for longitudinal studies

Vahe AvagyanStijn Vansteelandt

A1 Journal Article in SCANDINAVIAN JOURNAL OF STATISTICS

The importance of the urinary output criterion for the detection and prognostic meaning of AKI

Jill VanmassenhoveJohan SteenStijn VansteelandtPawel MorzywolekEric HosteJohan DecruyenaereDominique BenoitWim Van Biesen

A1 Journal Article in SCIENTIFIC REPORTS

Using generalized linear models to implement g‐estimation for survival data with time‐varying confounding

Shaun R. SeamanRuth H. KeoghOliver DukesStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Validity of self-reported data to assess the prevalence of overweight, hypertension and cholesterol

Ingrid PelgrimsBrecht DevleesschauwerK. DoggenS. VandevijvereE. M. De ClerqStijn VansteelandtJ. Van der Heyden

2020

Adjusting for time‐varying confounders in survival analysis using structural nested cumulative survival time models

Shaun SeamanOliver DukesRuth KeoghStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Authors' reply to 'Multiple comparisons controversies are about context and costs, not frequentism versus Bayesianism'

Arvid SjölanderStijn Vansteelandt

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Causal graphs for the analysis of genetic cohort data

Oliver HinesKarla Diaz-OrdazStijn VansteelandtYalda Jamshidi

A1 Journal Article in PHYSIOLOGICAL GENOMICS

Causal inference in meta-analysis and mediation analysis

Võ Tẩt ThẳngStijn VansteelandtRaphael Porcher

Comment : on the potential for misuse of outcome-wide study designs, and ways to prevent it

Stijn VansteelandtOliver Dukes

Editorial material

Doubly robust tests of exposure effects under high-dimensional confounding

Oliver DukesVahe AvagyanStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Estimating the effect of healthcare-associated infections on excess length of hospital stay using inverse probability-weighted survival curves

Koen B. PouwelsStijn VansteelandtRahul BatraJonathan EdgeworthSarah WordsworthJulie V. Robotham

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Estimation of controlled direct effects in longitudinal mediation analyses with latent variables in randomized studies

Wen Wei LohBeatrijs MoerkerkeTom LoeysLouise PoppeGeert CrombezStijn Vansteelandt

A1 Journal Article in MULTIVARIATE BEHAVIORAL RESEARCH

Ethical climate and intention to leave among critical care clinicians : an observational study in 68 intensive care units across Europe and the United States

Bo Van den BulckeVictoria MetaxaAnna K. ReynersKaterina RusinovaHanne I. JensenJ. MalmgrenMichael DarmonDaniel TalmorAnne-Pascale MeertLaura Cancelliere et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Heterogeneous indirect effects for multiple mediators using interventional effect models

Wen Wei LohBeatrijs MoerkerkeTom LoeysStijn Vansteelandt

A2 Journal Article in EPIDEMIOLOGIC METHODS

How to obtain valid tests and confidence intervals after propensity score variable selection?

Oliver DukesStijn Vansteelandt

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

Improving interim decisions in randomized trials by exploiting information on short-term endpoints and prognostic baseline covariates

Kelly Van LanckerAn VandeboschStijn Vansteelandt

A1 Journal Article in PHARMACEUTICAL STATISTICS

Instrumental variables estimation with competing risk data

Torben MartinussenStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

Longitudinal mediation analysis using natural effect models

Murthy N. MittintyStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Subtleties in the interpretation of hazard contrasts

Torben MartinussenStijn VansteelandtPer Kragh Andersen

A1 Journal Article in LIFETIME DATA ANALYSIS

The conduct and reporting of mediation analysis in recently published randomized controlled trials : results from a methodological systematic review

Tat-Thang VoCecilia SuperchiIsabelle BoutronStijn Vansteelandt

A1 Journal Article in JOURNAL OF CLINICAL EPIDEMIOLOGY

The hazards of period specific and weighted hazard ratios

Jonathan W. BartlettTim P. MorrisMats J. StensrudRhian M. DanielStijn VansteelandtCarl-Fredrik Burman

A1 Journal Article in STATISTICS IN BIOPHARMACEUTICAL RESEARCH

The obesity paradox in critically ill patients : a causal learning approach to a casual finding

Alexander DecruyenaereJohan SteenKirsten ColpaertDominique BenoitJohan DecruyenaereStijn Vansteelandt

A1 Journal Article in CRITICAL CARE

2019

A novel approach for identifying and addressing case‐mix heterogeneity in individual participant data meta‐analysis

Võ Tẩt ThẳngRaphael PorcherAnna ChaimaniStijn Vansteelandt

A1 Journal Article in RESEARCH SYNTHESIS METHODS

Adjusting the effect of integrating antiretroviral therapy and tuberculosis treatment on mortality for noncompliance : a time-varying instrumental variables analysis

Nonhlanhla Yende-ZumaHenry MwambiStijn Vansteelandt

A1 Journal Article in EPIDEMIOLOGY

Disentangling indirect effects through multiple mediators whose causal structure is unknown

Wen Wei LohBeatrijs MoerkerkeTom LoeysStijn Vansteelandt

Doubly robust conditional logistic regression

Johan ZetterqvistKarel VermeulenStijn VansteelandtArvid Sjölander

A1 Journal Article in STATISTICS IN MEDICINE

Estimation of conditional causal effects under model uncertainty

Oliver DukesStijn VansteelandtKirsten ColpaertJohan Decruyenaere

Evaluating futility of a binary clinical endpoint using early read‐outs

Kelly Van LanckerAn VandeboschStijn VansteelandtFilip De Ridder

A1 Journal Article in STATISTICS IN MEDICINE

Frequentist versus Bayesian approaches to multiple testing

Arvid SjölanderStijn Vansteelandt

A1 Journal Article in EUROPEAN JOURNAL OF EPIDEMIOLOGY

Instrumental variables estimation under a structural Cox model

Torben MartinussenDitte Nørbo SørensenStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

Mediation analysis

Johan SteenStijn Vansteelandt

Bookchapter in Handbook of graphical models

Mediation analysis of time‐to‐event endpoints accounting for repeatedly measured mediators subject to time‐varying confounding

Stijn VansteelandtMartin LinderSjouke VandenbergheJohan SteenJesper Madsen

A1 Journal Article in STATISTICS IN MEDICINE

Multistate models in critical care : two steps forward, one step back

Johan SteenStijn VansteelandtDominique BenoitJohan Decruyenaere

A1 Journal Article in CRITICAL CARE MEDICINE

On doubly robust estimation of the hazard difference

Oliver DukesTorben MartinussenEric J Tchetgen TchetgenStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Report of the editors : 2018

M BrewerD GhoshM GorfineStijn VansteelandtG Molenberghs

Editorial material

2018

A note on G-estimation of causal risk ratios

Oliver DukesStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Analysis of longitudinal studies with repeated outcome measures : adjusting for time-dependent confounding using conventional methods

Ruth H KeoghRhian M DanielTyler J VanderWeeleStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Augmented and doubly robust G-estimation of causal effects under a Structural nested failure time model

Karl MertensStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Eliminating survivor bias in two-stage instrumental variable estimators

Stijn VansteelandtStefan WalterEric Tchetgen Tchetgen

A1 Journal Article in EPIDEMIOLOGY

Ethical decision-making climate in the ICU : theoretical framework and validation of a self-assessment tool

Bo Van den BulckeRuth PiersHanne Irene JensenJohan MalmgrenVictoria MetaxaAnna K ReynersMichael DarmonKaterina RusinovaDaniel TalmorAnne-Pascale Meert et al.

A1 Journal Article in BMJ QUALITY & SAFETY

Improving the robustness and efficiency of covariate-adjusted linear instrumental variable estimators

Stijn VansteelandtVanessa Didelez

A1 Journal Article in SCANDINAVIAN JOURNAL OF STATISTICS

Intensive care unit (ICU)-acquired bacteraemia and ICU mortality and discharge : addressing time-varying confounding using appropriate methodology

KB PouwelsStijn VansteelandtR BatraJD EdgeworthT SmieszekJV Robotham

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

Introduction to double robust methods for incomplete data

Shaun R SeamanStijn Vansteelandt

Editorial material

Outcome in patients perceived as receiving excessive care across different ethical climates : a prospective study in 68 intensive care units in Europe and the USA

Dominique BenoitH. I. JensenJ. MalmgrenV. MetaxaA. K. ReynersM DarmonK. RusinovaD. TalmorA. P. MeertL. Cancelliere et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Perception of inappropriate cardiopulmonary resuscitation by clinicians working in emergency departments and ambulance services : the REAPPROPRIATE international, multi-centre, cross sectional survey

Patrick DruwéKoenraad G. MonsieursRuth PiersJames GaggShinji NakaharaEvan Avraham AlpertHans van SchuppenGábor ÉlőAnatolij TruhlářSofie A. Huybrechts et al.

A1 Journal Article in RESUSCITATION

Report of the Editors-2017

Michael J DanielsDebashis GhoshMalka GorfineStijn VansteelandtMarie DavidianGeert Molenberghs

Editorial material

Small sample inference for probabilistic index models

Gustavo AmorimOlivier ThasKarel VermeulenStijn VansteelandtJan De Neve

A1 Journal Article in COMPUTATIONAL STATISTICS & DATA ANALYSIS

Statistical models for causal mediation in within-subject designs : dealing with unmeasured confounders and interactions

Haeike JosephyTom LoeysStijn Vansteelandt

Survivor bias in Mendelian randomization analysis

Stijn VansteelandtOliver DukesTorben Martinussen

A1 Journal Article in BIOSTATISTICS

2017

Asking too much of epidemiologic studies : the problem of collider bias and the obesity paradox

Stijn Vansteelandt

Editorial material

Boosting the precision of mediation analyses of randomised experiments through covariate adjustment

Sjouke VandenbergheStijn VansteelandtTom Loeys

A1 Journal Article in STATISTICS IN MEDICINE

Does appropriate empiric antibiotic therapy modify intensive care unit-acquired Enterobacteriaceae bacteraemia mortality and discharge?

KB PouwelsE Van KleefStijn VansteelandtR BatraJD EdgeworthT SmieszekJV Robotham

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

Doubly robust estimation of attributable fractions in survival analysis

Arvid SjolanderStijn Vansteelandt

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

Flexible mediation analysis with multiple mediators

Johan SteenTom LoeysBeatrijs MoerkerkeStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Instrumental variables estimation of exposure effects on a time-to-event endpoint using structural cumulative survival models

Torben MartinussenStijn VansteelandtEric J Tchetgen TchetgenDavid M Zucker

A1 Journal Article in BIOMETRICS

Interventional effects for mediation analysis with multiple mediators

Stijn VansteelandtRhian M Daniel

A1 Journal Article in EPIDEMIOLOGY

medflex : an R package for flexible mediation analysis using natural effect models

Johan SteenTom LoeysBeatrijs MoerkerkeStijn Vansteelandt

A1 Journal Article in JOURNAL OF STATISTICAL SOFTWARE

Mediation analysis of randomised experiments

Sjouke VandenbergheStijn VansteelandtLuc Duchateau

Surrogate marker analysis in cancer clinical trials through time-to-event mediation techniques

Sjouke VandenbergheLuc DuchateauLeen SlaetsJan BogaertsStijn Vansteelandt

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

The potential and perils of observational studies

M BuyseStijn Vansteelandt

A1 Journal Article in ANNALS OF ONCOLOGY

2016

Assessing moderated mediation in linear models requires fewer confounding assumptions than assessing mediation

Tom LoeysWouter TalloenLiesbet GoubertBeatrijs MoerkerkeStijn Vansteelandt

A1 Journal Article in BRITISH JOURNAL OF MATHEMATICAL & STATISTICAL PSYCHOLOGY

Commentary: The formal approach to quantitative causal inference in epidemiology : misguided or misrepresented?

Rhian M DanielBianca L De StavolaStijn Vansteelandt

Editorial material

Data-adaptive bias-reduced doubly robust estimation

Karel VermeulenStijn Vansteelandt

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOSTATISTICS

Doubly robust methods for handling confounding by cluster

Johan ZetterqvistStijn VansteelandtYudi PawitanArvid Sjölander

A1 Journal Article in BIOSTATISTICS

Estimation of indirect effects in the presence of unmeasured confounding for the mediator-outcome relationship in a multilevel 2-1-1 mediation model

Wouter TalloenBeatrijs MoerkerkeTom LoeysJessie De NaeghelHilde Van KeerStijn Vansteelandt

A1 Journal Article in JOURNAL OF EDUCATIONAL AND BEHAVIORAL STATISTICS

Factors associated with low back pain before pubertal peak growth

Mieke DolphensStijn VansteelandtBarbara CagnieAdriaan VleemingGuy VanderstraetenLieven Danneels

Flexible causal mediation analysis using natural effect models

Johan SteenStijn VansteelandtTom LoeysBeatrijs Moerkerke

Marginal structural and structural nested models for causal inference in hospital epidemiology

Karl MertensStijn VansteelandtEls Goetghebeur

Multivariable modeling of factors associated with spinal pain in young adolescence

Mieke DolphensStijn VansteelandtBarbara CagnieAdriaan VleemingJo NijsGuy VanderstraetenLieven Danneels

A1 Journal Article in EUROPEAN SPINE JOURNAL

On the practice of ignoring center-patient interactions in evaluating hospital performance

Machteld VarewyckStijn VansteelandtMarie ErikssonEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Rejoinder : remaining challenges in investigating grade-retention effectiveness

Machteld VandecandelaereStijn Vansteelandt

Editorial material

The effect of adherence to statin therapy on cardiovascular mortality : quantification of unmeasured bias using falsification end-points

Maarten J BijlsmaStijn VansteelandtFanny JanssenEelko Hak

A1 Journal Article in BMC PUBLIC HEALTH

The effects of early grade retention: effect modification by prior achievement and age

Machteld VandecandelaereStijn VansteelandtBieke De FraineJan Van Damme

A1 Journal Article in JOURNAL OF SCHOOL PSYCHOLOGY

Time-varying treatments in observational studies : marginal structural models of the effects of early grade retention on math achievement

Machteld VandecandelaereStijn VansteelandtBieke De FraineJan Van Damme

A1 Journal Article in MULTIVARIATE BEHAVIORAL RESEARCH

2015

A cautionary note on the power of the test for the indirect effect in mediation analysis

Tom LoeysBeatrijs MoerkerkeStijn Vansteelandt

A1 Journal Article in FRONTIERS IN PSYCHOLOGY

Association between statin use and cardiovascular mortality at the population level: an ecologic study

Maarten J BijlsmaFanny JanssenJens BosPieter W KamphuisenStijn VansteelandtEelko Hak

A1 Journal Article in EPIDEMIOLOGY

Bias-reduced doubly robust estimation

Karel VermeulenStijn Vansteelandt

Bias-reduced doubly robust estimation

Karel VermeulenStijn Vansteelandt

A1 Journal Article in JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Birth cohort appeared to confound effect estimates of guideline changes on statin utilization

Maarten J BijlsmaFanny JanssenRené LubJens HJ BosFolgerdiena M De VriesStijn VansteelandtEelko Hak

A1 Journal Article in JOURNAL OF CLINICAL EPIDEMIOLOGY

Causal mediation analysis with multiple mediators

RM DanielBL De StavolaSN CousensStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneSabitri GhimireMado VandewoestyneYuechao LuJan GerrisRudy Van CosterTom DerooDieter DeforceStijn VansteelandtPetra De Sutter et al.

A1 Journal Article in CELL REPORTS

Factors associated with low back and neck pain in young adolescence : a multivariable modeling study

Mieke DolphensStijn VansteelandtBarbara CagnieJo NijsLieven Danneels

Gonadotropin therapy versus laparoscopic ovarian drilling in clomiphene citrate-resistant polycystic ovary syndrome patients: a retrospective cost-effectiveness analysis

Veerle De FrèneJan GerrisSteven WeyersMarc DhontStijn VansteelandtLieven AnnemansPetra De Sutter

A1 Journal Article in GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Increasing the power of the Mann-Whitney test in randomized experiments through flexible covariate adjustment

Karel VermeulenOlivier ThasStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

Instrumental variable estimation in a survival context

Eric J Tchetgen TchetgenStefan WalterStijn VansteelandtTorben MartinussenMaria Glymour

A1 Journal Article in EPIDEMIOLOGY

Medflex: flexible mediation analysis using natural effect models in R

Johan SteenTom LoeysBeatrijs MoerkerkeTheis LangeStijn Vansteelandt

On quantifying quality of care

Machteld VarewyckEls GoetghebeurStijn Vansteelandt

Structural equation modeling versus marginal structural modeling for assessing mediation in the presence of posttreatment confounding

Beatrijs MoerkerkeTom LoeysStijn Vansteelandt

A1 Journal Article in PSYCHOLOGICAL METHODS

Within-subject mediation analysis in AB/BA crossover designs

Haeike JosephyStijn VansteelandtMarie-Anne VanderhasseltTom Loeys

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOSTATISTICS

2014

A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome

Veerle De FrèneStijn VansteelandtGuy T'SjoenJan GerrisSara SomersL VercruyssePetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

A semi-parametric perspective

Stijn Vansteelandt

Bookchapter in Handbook of missing data methodology

Adding serum estradiol measurements to ultrasound monitoring does not change the yield of mature oocytes in IVF/ICSI

Frank VandekerckhoveJan GerrisStijn VansteelandtPetra De Sutter

A1 Journal Article in GYNECOLOGICAL ENDOCRINOLOGY

Adsorption of cyclic depsipeptide mycotoxins to glass

Lien TaevernierStijn VansteelandtBart De Spiegeleer

Delaying the oocyte maturation trigger by one day leads to a higher metaphase II oocyte yield in IVF/ICSI : a randomised controlled trial

Frank VandekerckhoveJan GerrisStijn VansteelandtAn De BaerdemaekerKelly TillemanPetra De Sutter

A1 Journal Article in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY

Double-robust methods

Andrea RotnitzkyStijn Vansteelandt

Bookchapter in Handbook of missing data methodology

Effect decomposition in the presence of an exposure-induced mediator-outcome confounder

Tyler J VanderWeeleStijn VansteelandtJames M Robins

A1 Journal Article in EPIDEMIOLOGY

Estimation of controlled direct effects in the presence of exposure-induced confounding and latent variables

Tom LoeysBeatrijs MoerkerkeAn RaesYves RosseelStijn Vansteelandt

A1 Journal Article in STRUCTURAL EQUATION MODELING-A MULTIDISCIPLINARY JOURNAL

Improving upon the efficiency of complete case analysis when covariates are MNAR

Jonathan W BartlettJames R CarpenterKate TillingStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

Imputation strategies for natural effect models probing mediation

Johan SteenTom LoeysBeatrijs MoerkerkeStijn Vansteelandt

Invited commentary: Some advantages of the relative excess risk due to interaction (RERI): towards better estimators of additive interaction

Tyler J VanderWeeleStijn Vansteelandt

Editorial material

Mediation analysis in AB/BA crossover studies

Haeike JosephyTom LoeysStijn Vansteelandt

Multivariable modeling of factors associated with spinal pain in young adolescence

Mieke DolphensStijn VansteelandtBarbara CagnieLieven Danneels

On adjustment for auxiliary covariates in additive hazard models for the analysis of randomized experiments

Stijn VansteelandtT MartinussenEJT Tchetgen

A1 Journal Article in BIOMETRIKA

On regression adjustment for the propensity score

Stijn VansteelandtRM Daniel

A1 Journal Article in STATISTICS IN MEDICINE

On shrinkage and model extrapolation in the evaluation of clinical center performance

Machteld VarewyckEls GoetghebeurMarie ErikssonStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

Preventable proportion of severe infections acquired in intensive care units: case-mix adjusted estimations from patient-based surveillance data

Marie-Laurence LambertGeert SilversmitAnne SaveyMercedes PalomarMichael HiesmayrAntonella AgodiBart Van RompayeKarl MertensStijn Vansteelandt

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Structural nested models and G-estimation : the partially realized promise

Stijn VansteelandtMarshall Joffe

A1 Journal Article in STATISTICAL SCIENCE

UHPLC-MS/MS method for the determination of the cyclic depsipeptide mycotoxins beauvericin and enniatins in in vitro transdermal experiments

Lien TaevernierLieselotte VeryserKirsten VandercruyssenMatthias D'HondtStijn VansteelandtSarah De SaegerBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

2013

A new approach for within-subject mediation analysis in AB/BA crossover designs

Haeike JosephyTom LoeysStijn Vansteelandt

A randomized controlled trial to evaluate the effect on oocyte yield of prolongating the follicular phase in IVF/ICSI cycles with not-elevated progesterone

Frank VandekerckhoveAn De BaerdemaekerJan GerrisKelly TillemanStijn VansteelandtPetra De Sutter

Flexible mediation analysis in the presence of nonlinear relations: beyond the mediation formula

Tom LoeysBeatrijs MoerkerkeOlivia De SmetAnn BuysseJohan SteenStijn Vansteelandt

A1 Journal Article in MULTIVARIATE BEHAVIORAL RESEARCH

Follicle measurements using sonography-based automated volume count accurately predict the yield of mature oocytes in in vitro fertilization/intracytoplasmic sperm injection cycles

Frank VandekerckhoveStijn VansteelandtJan GerrisPetra De Sutter

A1 Journal Article in GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Make the most of your samples : Bayes factor estimators for high-dimensional models of sequence evolution

Guy BaelePhilippe LemeyStijn Vansteelandt

A1 Journal Article in BMC BIOINFORMATICS

Mediation analysis with multiple mediators

Tyler VanderWeeleStijn Vansteelandt

A2 Journal Article in EPIDEMIOLOGIC METHODS

On collapsibility and confounding bias in Cox and Aalen regression models

Torben MartinussenStijn Vansteelandt

A1 Journal Article in LIFETIME DATA ANALYSIS

Pregnancy complications and perinatal outcome of obese versus non-obese PCOS women

Veerle De FrèneGuy T'SjoenStijn VansteelandtSara SomersLiesbeth VercruyssePetra De Sutter

Prospective, randomized trial on the effect of laser assisted hatching on frozen-thawed embryo transfer cycles

Ilse De CrooFrauke Vanden MeerschautStijn VansteelandtEtienne Van den AbbeelPetra De Sutter

Testing for direct genetic effects using a screening step in family-based association studies

Sharon M LutzStijn VansteelandtChristoph Lange

A2 Journal Article in FRONTIERS IN GENETICS

2012

A simple unified approach for estimating natural direct and indirect effects

Theis LangeStijn VansteelandtMaarten Bekaert

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Causation and causal inference for genetic effects

Stijn VansteelandtChristoph Lange

A1 Journal Article in HUMAN GENETICS

Direct genetic effects and their estimation from matched case-control data

Carlo BerzuiniStijn VansteelandtLuisa FocoRoberta PastorinoLuisa Bernardinelli

A1 Journal Article in GENETIC EPIDEMIOLOGY

Stijn Vansteelandt

Editorial material

Estimation of direct and indirect effects

Stijn Vansteelandt

Bookchapter in Causality : statistical perspectives and applications

From parametric towards nonparametric mixed modeling of correlated data

Fanghong ZhangStijn VansteelandtOlivier ThasMarnik Vuylsteke

Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach

David W FardoJinze LiuDawn L DemeoEdwin K SilvermanStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

Imputation strategies for the estimation of natural direct and indirect effects

Stijn VansteelandtMaarten BekaertTheis Lange

A2 Journal Article in EPIDEMIOLOGIC METHODS

Natural direct and indirect effects on the exposed : effect decomposition under weaker assumptions

Stijn VansteelandtTyler J VanderWeele

A1 Journal Article in BIOMETRICS

On model selection and model misspecification in causal inference

Stijn VansteelandtMaarten BekaertGerda Claeskens

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

Parental socioeconomic status and soft drink consumption of the child: the mediating proportion of parenting practices

Valerie De CoenStijn VansteelandtLea MaesInge HuybrechtsIlse De BourdeaudhuijCarine Vereecken

A1 Journal Article in APPETITE

Semiparametric tests for sufficient cause interaction

Stijn VansteelandtTyler J VanderWeeleJames M Robins

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Understanding counterfactual-based mediation analysis approaches and their differences

Stijn Vansteelandt

Editorial material

2011

A weighting approach to causal effects and additive interaction in case-control studies: marginal structural linear odds models

Tyler J VanderWeeleStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Age-disparity, sexual connectedness and HIV infection in disadvantaged communities around Cape Town, South Africa: a study protocol

Wim DelvaRoxanne BeauclairAlex WelteStijn VansteelandtNiel HensMarc AertsElizabeth du ToitNulda BeyersMarleen Temmerman

A1 Journal Article in BMC PUBLIC HEALTH

Attributable mortality of ventilator associated pneumonia: a reappraisal using causal analysis

Maarten BekaertJean-Francois TimsitStijn VansteelandtPieter DepuydtAurélien VésinMaité Garrouste-OrgeasJohan DecruyenaereChristoph Clec'hElie AzoulayDominique Benoit

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Combining disease models to test for gene-environment interaction in nuclear families

Thomas J HoffmannStijn VansteelandtChristoph LangeEdwin K SilvermanDawn L DeMeoNan M Laird

A1 Journal Article in BIOMETRICS

Context-dependent codon partition models provide significant increases in model fit in atpB and rbcL protein-coding genes

Guy BaeleYves Van de PeerStijn Vansteelandt

A1 Journal Article in BMC EVOLUTIONARY BIOLOGY

Do patients die from or with infection? : finding the answer through causal analysis of longitudinal intensive care unit data

Maarten BekaertStijn VansteelandtDominique Benoit

Doubly robust estimation of attributable fractions

Arvid SjolanderStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

Estimation of direct effects for survival data by using the Aalen additive hazards model

Torben MartinussenStijn VansteelandtMette GersterJacob von Bornemann Hjelmborg

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Estimation of HIV treatment-efficacy by combining structural nested mean models with pharmacokinetic models of antiretroviral drug exposure

Laetitia ComtéStijn VansteelandtRichard A RodeBernard Vrijens

A1 Journal Article in STATISTICS AND ITS INTERFACE

Invited commentary: G-Computation-lost in translation?

Stijn VansteelandtNiels Keiding

Editorial material

Ion mobility spectrometry as a high-throughput technique for in vitro transdermal Franz diffusion cell experiments of ibuprofen

Bram BaertStijn VansteelandtBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Mendelian randomization analysis of case-control data using structural mean models

Jack BowdenStijn Vansteelandt

A1 Journal Article in STATISTICS IN MEDICINE

On instrumental variables estimation of causal odds ratios

Stijn VansteelandtJack BowdenManoochehr BabanezhadEls Goetghebeur

A1 Journal Article in STATISTICAL SCIENCE

Quality assurance of rectal cancer diagnosis and treatment - phase 3 : statistical methods to benchmark centres on a set of quality indicators

Els GoetghebeurRonan Van RossemKatrien BaertKürt VanhoutteTom BoterbergPieter DemetterMark De RidderDavid HarringtonMarc PeetersGuy Storme et al.

Serial measurements of mesothelioma serum biomarkers in asbestos-exposed individuals: a prospective longitudinal cohort study

Kevin HollevoetJoris Van CleemputJoel ThimpontPaul De VuystLionel BosqueeKristiaan NackaertsPaul GermonpreStijn VansteelandtYoshiro KishiJoris Delanghe et al.

A1 Journal Article in JOURNAL OF THORACIC ONCOLOGY

2010

A doubly robust test for gene-environment interaction in family-based studies of affected offspring

Beatrijs MoerkerkeStijn VansteelandtChristoph Lange

A1 Journal Article in BIOSTATISTICS

A note on statistical association and causality derived from epidemiological ICU data: reply

Maarten BekaertDominique BenoitJohan DecruyenaereStijn Vansteelandt

A1 Journal Article in INTENSIVE CARE MEDICINE

A principal stratification approach to assess the differences in prognosis between cancers caused by hormone replacement therapy and by other factors

Arvid SjolanderStijn VansteelandtKeith Humphreys

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOSTATISTICS

A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts

R ErkkolaS VervarckeStijn VansteelandtP RompottiDenis De KeukeleireArne Heyerick

A1 Journal Article in PHYTOMEDICINE

Adjusting for time-varying confounding in the subdistribution analysis of a competing risk

Maarten BekaertStijn VansteelandtKarl Mertens

A1 Journal Article in LIFETIME DATA ANALYSIS

Analysis of incomplete data using inverse probability weighting and doubly robust estimators

Stijn VansteelandtJames CarpenterMichael G Kenward

A1 Journal Article in METHODOLOGY-EUROPEAN JOURNAL OF RESEARCH METHODS FOR THE BEHAVIORAL AND SOCIAL SCIENCES

Comparison of causal effect estimators under exposure misclassification

Manoochehr BabanezhadStijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF STATISTICAL PLANNING AND INFERENCE

Estimation of controlled direct effects on a dichotomous outcome using logistic structural direct effect models

Stijn Vansteelandt

A1 Journal Article in BIOMETRIKA

Marginal structural models for sufficient cause interactions

Tyler J Vander WeeleStijn VansteelandtJames M Robins

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Modelling the ancestral sequence distribution and model frequencies in context-dependent models for primate non-coding sequences

Guy BaeleYves Van de PeerStijn Vansteelandt

A1 Journal Article in BMC EVOLUTIONARY BIOLOGY

Odds ratios for mediation analysis for a dichotomous outcome

Tyler J VanderWeeleStijn Vansteelandt

A1 Journal Article in AMERICAN JOURNAL OF EPIDEMIOLOGY

Parsing the effects of individual SNPs in candidate genes with family data

Thomas J HoffmannChristoph LangeStijn VansteelandtBenjamin A RabyDawn L DeMeoEdwin K SilvermanScott T WeissNan M Laird

A1 Journal Article in HUMAN HEREDITY

Predictability of cerebral palsy in a high-risk neonatal intensive care unit population

Eveline HimpensAnn OostraInge FrankiStijn VansteelandtPiet VanhaesebrouckChristine Van den Broeck

Predictability of cerebral palsy in a high-risk NICU population

Eveline HimpensAnn OostraInge FrankiStijn VansteelandtPiet VanhaesebrouckChristine Van den Broeck

Predictability of cerebral palsy in a high-risk NICU population

Eveline HimpensAnn OostraInge FrankiStijn VansteelandtPiet VanhaesebrouckChristine Van den Broeck

A1 Journal Article in EARLY HUMAN DEVELOPMENT

Pregnancy outcomes of naturally conceived singletons and singletons after elective single embryo transfer (eSET) are comparable

Ilse DelbaereJan GerrisDiane De NeubourgStijn VansteelandtGuy MartensPaul VerdonkPetra De SutterMarleen Temmerman

Sexual behaviour and the spread of HIV: statistical and epidemiological modelling applications

Wim DelvaMarleen TemmermanStijn Vansteelandt

Using non-reversible context-dependent evolutionary models to study substitution patterns in primate non-coding sequences

Guy BaeleYves Van de PeerStijn Vansteelandt

A1 Journal Article in JOURNAL OF MOLECULAR EVOLUTION

VanderWeele and Vansteelandt respond to 'decomposing with a lot of supposing' and 'mediation'

Tyler J VanderWeeleStijn Vansteelandt

Editorial material

2009

Conceptual issues concerning mediation, interventions and composition

Tyler VanderWeeleStijn Vansteelandt

A2 Journal Article in Statistics and Its Interface

CORRECTING INSTRUMENTAL VARIABLES ESTIMATORS FOR SYSTEMATIC MEASUREMENT ERROR

Stijn VansteelandtManoochehr BabanezhadEls Goetghebeur

A1 Journal Article in STATISTICA SINICA

Discussion on "Identifiability and Estimation of Causal Effects in Randomized Trials with Noncompliance and Completely Nonignorable Missing Data"

Stijn Vansteelandt

Editorial material

Efficient context-dependent model building based on clustering posterior distributions for non-coding sequences

Guy BaeleYves Van de PeerStijn Vansteelandt

A1 Journal Article in BMC Evolutionary Biology

Estimating direct effects in cohort and case-control studies

Stijn Vansteelandt

A1 Journal Article in EPIDEMIOLOGY

EVOLUTION IN COAGULATION PARAMETERS OVER THE FIRST 3 DAYS OF ICU ADMISSION IN SEPTIC SHOCK PATIENTS: IMPACT ON 30 DAY MORTALITY

Maarten BekaertJOKE NOLLETPieter DepuydtJohan DecruyenaereJan De WaeleCHRISTIAN DANNEELSStijn VansteelandtDominique Benoit

EXCESS RISK OF DEATH FROM VENTILATOR ASSOCIATED PNEUMONIA: A REAPPRAISAL USING LONGITUDINAL CAUSAL ANALYSIS

Maarten BekaertJF TimsitJohan DecruyenaereM Garrouste-OrgeasE AzoulayD Goldgran-ToledanoStijn VansteelandtDominique Benoit

Gene-Environment Interaction Tests for Dichotomous Traits in Trios and Sibships

TJ HoffmannC LangeStijn VansteelandtNM Laird

A1 Journal Article in GENETIC EPIDEMIOLOGY

Linear and loglinear structural mean models to evaluate the benefits of an on-demand dosing regimen

Laetitia ComteStijn VansteelandtEric ToussetBernard Vrijens

A1 Journal Article in Clinical Trials

Marginal structural models for partial exposure regimes

Stijn VansteelandtKarl MertensCarl SuetensEls Goetghebeur

A1 Journal Article in BIOSTATISTICS

Measurement error and causal inference with instrumental variables

Manoochehr BabanezhadEls GoetghebeurStijn Vansteelandt

On the Adjustment for Covariates in Genetic Association Analysis: A Novel, Simple Principle to Infer Direct Causal Effects

Stijn VansteelandtSylvie GoetgelukS LutzI WaldmanH LyonEE SchadtST WeissC Lange

A1 Journal Article in GENETIC EPIDEMIOLOGY

Psychological well-being and socio-economic hardship among AIDS orphans and other vulnerable children in Guinea

Wim DelvaAN VERCOUTERECatherine LouaJonas LamahStijn VansteelandtPetra De KokerPatricia ClaeysMarleen TemmermanLieven Annemans

A1 Journal Article in AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV

Sensitivity Analysis for Principal Stratum Direct Effects, with an Application to a Study of Physical Activity and Coronary Heart Disease

A SjolanderK HumphreysStijn VansteelandtR BelloccoJ Palmgren

A1 Journal Article in BIOMETRICS

The efficacy of the embryo transfer catheter in IVF and ICSI is operator-dependent: a randomized clinical trial

Zhan YaoStijn VansteelandtJosiane Van der ElstTom CoetsierMarc DhontPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

2008

A model-based approach to study nearest-neighbor influences reveals complex substitution patterns in non-coding sequences

Guy BaeleYves Van de PeerStijn Vansteelandt

A1 Journal Article in SYSTEMATIC BIOLOGY

Conditional generalized estimating equations for the analysis of clustered and longitudinal data

Sylvie GoetgelukStijn Vansteelandt

A1 Journal Article in BIOMETRICS

Detecting complex substitution patterns in non-coding sequences

Guy BaeleStijn VansteelandtYves Van de Peer

Estimation of controlled direct effects

Sylvie GoetgelukStijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

From clustered data to causal inference : new methodology motivated by the analysis of subfertility treatments

Sylvie GoetgelukStijn VansteelandtEls Goetghebeur

HIV Testing and Sexually Transmitted Infection Care among Sexually Active Youth in the Balkans

Wim DelvaFrançoise WuillaumeStijn VansteelandtPatricia ClaeysHans VerstraelenDavy Vanden BroeckMarleen Temmerman

A1 Journal Article in AIDS PATIENT CARE AND STDS

Human chorionic gonadotropin levels in early IVF/ICSI pregnancies are higher in singletons after single embryo transfer compared with singletons after double embryo transfer

Ilse DelbaereStijn VansteelandtJan GerrisPetra De SutterDirk De BacquerMarleen Temmerman

A1 Journal Article in HUMAN REPRODUCTION

Lesson of the month: Natural history and clearance of HPV after treatment of precancerous cervical lesions

Annelies AerssensPatricia ClaeysA GarciaYolande SturtewagenR VelasquezDavy Vanden BroeckStijn VansteelandtMarleen TemmermanCA Cuvelier

A1 Journal Article in HISTOPATHOLOGY

Multiply Robust Inference for Statistical Interactions

Stijn VansteelandtTyler VanderweeleEric TchetgenJames Robins

A1 Journal Article in JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Support Vector machine versus logistic regression modeling for prediction of hospital mortality in critically ill patients with haematological malignancies

Thierry VerplanckeStijn Van LooyDominique BenoitStijn VansteelandtPieter DepuydtFilip De TurckJohan Decruyenaere

A1 Journal Article in BMC MEDICAL INFORMATICS AND DECISION MAKING

Testing and estimating gene-environment interactions in family-based association studies

Stijn VansteelandtDawn DeMeoJessica Lasky-SuJordan SmollerAmy MurphyMatt McQueenKady SchneiterJuan CeledonScott WeissEdwin Silverman et al.

A1 Journal Article in BIOMETRICS

The decline of serum testosterone levels in community-dwelling men over 70 years of age: descriptive data and predictors of longitudinal changes.

Bruno LapauwStefan GoemaereHans-Georg ZmierczakI VAN POTTELBERGHAhmed MahmoudYouri TaesDirk De BacquerStijn VansteelandtJean Kaufman

A1 Journal Article in EUROPEAN JOURNAL OF ENDOCRINOLOGY

2007

An evaluation of 2D-image analysis techniques for measuring soil microporosity

Vera de Melo MarcelinoVeerle CnuddeStijn VansteelandtF Carò

A1 Journal Article in EUROPEAN JOURNAL OF SOIL SCIENCE

Estimation of regression models for the mean of repeated outcomes under nonignorable nonmonotone nonresponse

Stijn VansteelandtA ROTNITZKYJ ROBINS

A1 Journal Article in BIOMETRIKA

On confounding, prediction and efficiency in the analysis of longitudinal and cross-sectional clustered data

Stijn Vansteelandt

A1 Journal Article in SCANDINAVIAN JOURNAL OF STATISTICS

Principal stratification designs to estimate input data missing due to death - Discussion

J ROBINSA ROTNITZKYStijn Vansteelandt

Editorial material

Sexual behaviour and contraceptive use among youth in the Balkans

Wim DelvaF WUILLAUMEStijn VansteelandtPatricia ClaeysHans VerstraelenMarleen Temmerman

A1 Journal Article in EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE

Should we adjust for gestational age when analysing birth weights? The use of z-scores revisited

Ilse DelbaereStijn VansteelandtDirk De BacquerHans VerstraelenJan GerrisPetra De SutterMarleen Temmerman

A1 Journal Article in HUMAN REPRODUCTION

2006

A comparison of multiple imputation and doubly robust estimation for analyses with missing data

JR CARPENTERMG KENWARDStijn Vansteelandt

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

An improved statistical method for detecting heterotachy in nucleotide sequences

Guy BaeleJeroen RaesYves Van de PeerStijn Vansteelandt

A1 Journal Article in MOLECULAR BIOLOGY AND EVOLUTION

Ignorance and uncertainty regions as inferential tools in a sensitivity analysis

Stijn VansteelandtEls GoetghebeurMG KENWARDG MOLENBERGHS

A1 Journal Article in STATISTICA SINICA

2005

Least squares estimation

Stijn VansteelandtEls Goetghebeur

Bookchapter in Encyclopaedic Companion to Medical Statistics

Maximum likelihood estimation

Stijn VansteelandtEls Goetghebeur

Bookchapter in Encyclopaedic Companion to Medical Statistics

Els GoetghebeurStijn Vansteelandt

Bookchapter in Encyclopaedic Companion to Medical Statistics

On the viral safety of plasma pools and plasma derivatives

Stijn VansteelandtEls GoetghebeurI THOMASE MATHYSF VAN LOOCK

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

Preterm birth in twins after subfertility treatment: population based cohort study

Hans VerstraelenSylvie GoetgelukC DEROMStijn VansteelandtRobert DeromEls GoetghebeurNA TEMMERMAN

A1 Journal Article in BRITISH MEDICAL JOURNAL

Sense and sensitivity when correcting for observed exposures in randomized clinical trials

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Structural mean models for compliance analysis in randomized clinical trials and the impact of errors on measures of exposure

Els GoetghebeurStijn Vansteelandt

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

2004

Bacterial vaginosis: not a risk factor for preterm birth?

Hans VerstraelenStijn VansteelandtMarleen Temmerman

A1 Journal Article in BRITISH JOURNAL OF GENERAL PRACTICE

Both low and high activities of platelet monoamine oxidase increase the probability of becoming a smoker

J HARROK FISCHERStijn VansteelandtM HARRO

A1 Journal Article in EUROPEAN NEUROPSYCHOPHARMACOLOGY

Statistical methods for drawing causal effects from twin studies

Sylvie GoetgelukStijn VansteelandtHans VerstraelenC DEROMRobert DeromMarc DhontMarleen Temmerman

Using potential outcomes as predictors of treatment activity via strong structural mean models

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in STATISTICA SINICA

2003

Causal inference with generalized structural mean models

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Discussion of `Causation and Graphical Models?

Stijn Vansteelandt

Distribution of human papillomavirus in a family planning population in Nairobi, Kenya

H DE VUYSTS STEYAERTL VAN RENTERGHEMPatricia ClaeysL MUCHIRIS SITATIStijn VansteelandtW QUINTB KLETERE VAN MARCK et al.

A1 Journal Article in SEXUALLY TRANSMITTED DISEASES

2002

Discussion of Clustered encouragement designs with individual noncompliance: Bayesian inference with randomization, and application to advance directive forms' by Frangacis, Rubin and Zhou.

Els GoetghebeurStijn Vansteelandt

Editorial material

Placental inflammation and perinatal transmission of HIV-1

Fabian MwanyumbaPhilippe GaillardIngrid InionChris VerhofstedePatricia ClaeysVarsha ChohanStijn VansteelandtKishorchandra MandaliyaMarleen PraetMarleen Temmerman

A1 Journal Article in JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

2001

Accounting for correlation and compliance in cluster randomized trials.

Tom LoeysStijn VansteelandtEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Analyzing the sensitivity of generalized linear models to incomplete outcomes via the IDE algorithm

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS

2000

Regression models for disease prevalence with diagnostic tests on pools of serum samples.

Stijn VansteelandtEls GoetghebeurT VERSTRAETEN

A1 Journal Article in BIOMETRICS

Sensitivity Analysis for Incomplete Data: Ignoring Bounds or Bounding Ignorance?

Stijn VansteelandtEls Goetghebeur

1999

Adjusting for confouding when estimating a time trend in HIV prevalence based on pooled serum samples

Stijn VansteelandtEls GoetghebeurT Verstraeten

A2 Journal Article in ARCHIVES OF PUBLIC HEALTH