Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Stijn Vanhee

Awards & Distinctions

31 Results

2024

Lack of functional TCR-epitope interaction is associated with herpes zoster through reduced downstream T cell activation

Marlies BoerenNicky de VrijMy K. HaSebastiaan ValkiersAisha SouquetteSofie GielisMaria KuznetsovaJolien SchippersEsther BartholomeusJohan Van den Bergh et al.

A1 Journal Article in CELL REPORTS

TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

Nincy DebeufSahine LameireManon VanheerswynghelsJulie DeckersCaroline De WolfWendy ToussaintRein VerbekeKevin VerstaenHamida HammadStijn Vanhee et al.

Unraveling inflammation in chronic rhinosinusitis : from endotyping to impact of biologicals

Sharon Van NevelClaus BachertPhilippe GevaertStijn Vanhee

2023

Effects of biologics treatment in type 2-high chronic rhinosinusitis with nasal polyp patients

Sharon Van NevelTim MeeseGabriële HoltappelsNatalie De RuyckStijn VanheeNan ZhangFilip Van NieuwerburghClaus Bachert

Enhanced protein synthesis is a defining requirement for neonatal B cell development

Hugo ÅkerstrandElena BoldrinGiorgia MontanoStijn VanheeKarin OlssonNiklas KrausseStefano VerganiMaciej CieślaCristian BellodiJoan Yuan

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

RNA viruses alter house dust mite physiology and allergen production with no detected consequences for allergenicity

José Cristian Vidal‐QuistJozefien DeclercqStijn VanheeBart LambrechtJosé Gómez‐RialCarmen VidalEylem Aydogdu LohausStephane RombautsPedro Hernández‐Crespo

A1 Journal Article in INSECT MOLECULAR BIOLOGY

The multi-omics single-cell landscape of sinus mucosa in uncontrolled severe chronic rhinosinusitis with nasal polyps

Zhaofeng XuYanran HuangTim MeeseSharon Van NevelGabriële HoltappelsStijn VanheeBarbara M. BrökerZhengqi LiEllen De MeesterNatalie De Ruyck et al.

A1 Journal Article in CLINICAL IMMUNOLOGY

2022

A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut

Stefano VerganiKonjit Getachew MuletaClément Da SilvaAlexander DoyleTrine Ahn KristiansenSelene SodiniNiklas KrausseGiorgia MontanoKnut KotarskyJoy Nakawesi et al.

A1 Journal Article in IMMUNITY

COVID‐19 vaccination with BNT162b2 and ChAdOx1 vaccines has the potential to induce nasal neutralizing antibodies

Jozefien DeclercqEls TobbackStijn VanheeNatalie De RuyckSarah GerloPhilippe GevaertLinos Vandekerckhove

A1 Journal Article in ALLERGY

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCédric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2021

Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice

Tim PietersSara T'SasStijn VanheeAndré Pedro Pinto De AlmeidaYasmine DriegeJuliette RoelsWouter Van LoockeWillem DaneelsMathijs BaensArnaud Marchand et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

DALI (Diversity AnaLysis Interface) : a novel tool for the integrated analysis of multimodal single cell RNAseq data and immune receptor profiling

Kevin VerstaenInés LammensJana RoelsYvan SaeysBart LambrechtNiels VandammeStijn Vanhee

2019

Lin28b controls a neonatal to adult switch in B cell positive selection

Stijn VanheeHugo ÅkerstrandTrine Ahn KristiansenSebak DattaGiorgia MontanoStefano VerganiStefan LangJonas UngerbäckAlexander DoyleKarin Olsson et al.

A1 Journal Article in Science Immunology

2017

PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice

Dan SuStijn VanheeRebeca SoriaElin Jaensson GyllenbäckLinda M. StarnesMartina Kubec HøjfeldtGabriel K. PedersenJoan YuanJeremy A. Daniel

A1 Journal Article in Proceedings of the National Academy of Sciences

The influence of developmental timing on B cell diversity

Trine A KristiansenStijn VanheeJoan Yuan

A1 Journal Article in Current Opinion in Immunology

2016

Fetal to Adult Hematopoiesis with the “Flk” of a Switch

Stijn VanheeJoan Yuan

Editorial material

Humanized mice to study human T cell development

Sarah BonteSylvia SnauwaertStijn VanheeAnne-Catherine DolensTom TaghonBart VandekerckhoveTessa Kerre

Bookchapter in T-Cell development : methods and protocols

2015

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemGreet VerstichelNadine Van RoyBjörn MentenImke VelgheJan PhilippéDominique De BleserBart Lambrecht et al.

A1 Journal Article in HAEMATOLOGICA

In vitro studies on human hematopoiesis

Stijn VanheeBart VandekerckhoveTessa Kerre

Pluripotent stem cell based gene therapy for hematological diseases

Stijn VanheeBart Vandekerckhove

A1 Journal Article in CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

2014

In vitro and in vivo functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSylvia SnauwaertGlenn GoetgelukH StaussR StripeckeM HeemskerkYasmine Van CaeneghemGreet VerstichelStijn VanheeBart Vandekerckhove et al.

In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection

Sylvia SnauwaertGreet VerstichelSarah BonteGlenn GoetgelukStijn VanheeYasmine Van CaeneghemKatrien De MulderCarlo HeirmanHans StaussMiriam HM Heemskerk et al.

A1 Journal Article in LEUKEMIA

In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemNadine Van RoyBjörn MentenImke VelgheJan PhilippéTom TaghonGeorges LeclercqTessa Kerre et al.

2013

CMYB expression during human in vitro hematopoiesis

Stijn VanheeYasmine Van CaeneghemKatrien De MulderImke VelgheSylvie TaveirneNadine Van RoyBjörn MentenSylvia SnauwaertGreet VerstichelMelissa Dullaers et al.

In vitro generation of antigen-specific T-cells from CD34+haematopoietic progenitor cells: a new and promising immunotherapeutic strategy

Sylvia SnauwaertS Van CoppernolleGreet VerstichelGlenn GoetgelukYasmine Van CaeneghemStijn VanheeImke VelgheJean PlumTessa KerreBart Vandekerckhove

Vpr content of HIV-1 virions determines infection of resting peripheral blood CD4⁺ lymphocytes

Anouk Van NuffelFrancis ImpensAnn BaeyensStijn VanheeWojciech WitkowskiElien VandermarliereHanne VanderstraetenEvelien NaessensKathleen Van LandeghemSophie Vermaut et al.

2012

Evaluation of the receptor for hyaluronic acid mediated motility as a tumour-specific antigen in AML

Sylvia SnauwaertStijn VanheeYasmine Van CaeneghemGreet VerstichelGlenn GoetgelukImke VelgheBart VandekerckhoveTessa Kerre

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway

Stefanie Van CoppernolleStijn VanheeGreet VerstichelSylvia SnauwaertA van der SpekImke VelgheMieke SinnesaelMH HeemskerkTom TaghonGeorges Leclercq et al.

A1 Journal Article in LEUKEMIA

RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia

Sylvia SnauwaertStijn VanheeGlenn GoetgelukGreet VerstichelYasmine Van CaeneghemImke VelgheJan PhilippéZwi N BernemanJean PlumTom Taghon et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

2011

Double positive and double negative TCR gamma delta plus cells independently generate mature functional TCR gamma delta plus cells in the human thymus

Stefanie Van CoppernolleStijn VanheeGreet VerstichelSylvia SnauwaertImke VelgheMieke SinnesaelA van der SpekTom TaghonGeorges LeclercqJean Plum et al.

In vitro generation of immune cells from pluripotent stem cells

Bart VandekerckhoveStijn VanheeStefanie Van CoppernolleSylvia SnauwaertImke VelgheTom TaghonGeorges LeclercqTessa KerreJean Plum

A1 Journal Article in FRONTIERS IN BIOSCIENCE-LANDMARK