Research Explorer

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Researcher

Steve Schoonooghe

18 Results

2017

Hierarchical and redundant roles of activating FcγRs in protection against influenza disease by M2e-specific IgG1 and IgG2a antibodies

Silvie Van den HoeckeKatrin EhrhardtAnnasaheb KolpeKarim El BakkouriLei DengHendrik GrootaertSteve SchoonoogheAnouk SmetMostafa BentahirKenny RooseMichael SchotsaertBert SchepensNico CallewaertFalk NimmerjahnPeter StaeheliHartmut HengelXavier Saelens

A1 Journal Article in JOURNAL OF VIROLOGY

2013

Generation and in vivo characterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives

Caroline DumolynSteve SchoonoogheLieselotte MoermanSara NeytJurgen HaustraeteFilip De Vos

A2 Journal Article in EJNMMI RESEARCH

2012

Production of antibody derivatives in the methylotrophic yeast Pichia pastoris

Steve SchoonoogheJannick LeoenJurgen Haustraete

Bookchapter in Antibody engineering

2010

PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1

Steve SchoonoogheIngrid BurvenichLiesbet VervoortFilip De VosNico MertensJohan Grooten

A1 Journal Article in PROTEIN ENGINEERING DESIGN & SELECTION

2009

Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris

Steve SchoonoogheVladimir KaigorodovMonika ZawiszaCaroline DumolynJurgen HaustraeteJohan GrootenNico Mertens

A1 Journal Article in BMC BIOTECHNOLOGY

2008

Monoclonal antibody 14C5 targets integrin alpha(v)beta(3)

Ingrid BurvenichSteve SchoonoogheLiesbet VervoortCaroline DumolynElisabeth CoeneLieve VANWALLEGHEMJacques Van HuysseMarleen PraetClaude CuvelierNico MertensFilip De VosGuido Slegers

A1 Journal Article in MOLECULAR CANCER THERAPEUTICS

2007

Biodistribution and planar gamma camera imaging of I-123- and I-131-labeled F(ab ')(2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor

Ingrid BurvenichSteve SchoonooghePETER BLANCKAERTKlaus BacherLiesbet VervoortElisabeth CoeneNico MertensFilip De VosGuido Slegers

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

2005

CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation

An WillemsSteve SchoonoogheDominique EeckhoutGeert De JaegerJohan GrootenNico Mertens

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model

Ingrid BurvenichSteve SchoonoogheBart CornelissenPETER BLANCKAERTElisabeth CoeneClaude CuvelierNico MertensGuido Slegers

A1 Journal Article in CLINICAL CANCER RESEARCH

2004

123I-labelled monoclonal antibody 14C5 for SPECT tumour imaging: In vivo evaluation of athymic mice bearing a LoVo tumour

Ingrid BurvenichBart CornelissenPETER BLANCKAERTElisabeth CoeneClaude CuvelierGuido SlegersSteve SchoonoogheNico Mertens

Improved targeting with F(ab)2 fragments of monoclonal antibody 14C5 for imaging and therapy of metastatic disease

Ingrid BurvenichKaren JanssenPETER BLANCKAERTSteve SchoonoogheElisabeth CoeneClaude CuvelierNico MertensGuido Slegers

Internalization and cellular processing of radiolabeled monoclonal antibody 14C5

Ingrid BurvenichSteve SchoonoogheRuth OltenfreiterPeter BlanckaertE COENEClaude CuvelierN MERTENSGuido Slegers

New strategies in polypeptide and antibody synthesis: An overview

Nico MertensF DEVOSJannick LeoenEls Van DeynseAn WillemsSteve SchoonoogheIngrid BurvenichStefaan De KokerDominique VliegheJohan GrootenA KELLYChristophe Van De Wiele

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Targeting properties of radiolabelled monoclonal antibody 14c5 directed against a cell substrate adhesion molecule

Ingrid BurvenichSteve SchoonooghePETER BLANCKAERTElisabeth CoeneBart CornelissenClaude CuvelierNico MertensGuido Slegers

2003

Optimizing expression and purification from cell culture medium of trispecific recombinant antibody derivatives

An WillemsJ LSteve SchoonoogheJohan GrootenNico Mertens

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2001

A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain.

Reinhilde SchoonjansAn WillemsSteve SchoonoogheJ LEOENJohan GrootenNico Mertens

A1 Journal Article in BIOMOLECULAR ENGINEERING

New recombinant bi- and trispecific antibody derivatives

Nico MertensReinhilde SchoonjansAn WillemsSteve SchoonoogheJ LJohan Grooten

2000

Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives.

Reinhilde SchoonjansAn WillemsSteve SchoonoogheWalter FiersJohan GrootenNico Mertens

A1 Journal Article in JOURNAL OF IMMUNOLOGY