Research Explorer

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Researcher

Sofie Stalmans

Awards & Distinctions

32 Results

2021

Effects of backbone cyclization on the pharmacokinetics and drug efficiency of the orally active analgesic conotoxin cVc1.1

Aaron G. PothFrancis C.K. ChiuSofie StalmansBrett R. HamiltonYen-Hua HuangDavid M. ShacklefordRahul PatilThao T. LeMeng-Wei KanThomas Durek et al.

A2 Journal Article in MEDICINE IN DRUG DISCOVERY

2016

Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT

Bert GevaertEvelien WynendaeleSofie StalmansNathalie BrackeMatthias D'HondtIlse SmoldersAnn Van EeckhautBart De Spiegeleer

A1 Journal Article in NEUROPHARMACOLOGY

Exploration of the medicinal peptide space

Bert GevaertSofie StalmansEvelien WynendaeleLien TaevernierNathalie BrackeMatthias D'HondtBart De Spiegeleer

A1 Journal Article in PROTEIN AND PEPTIDE LETTERS

Mucosal and blood-brain barrier transport kinetics of the plant N-alkylamide spilanthol using in vitro and in vivo models

Lieselotte VeryserLien TaevernierTanmayee JoshiPratima TatkeEvelien WynendaeleNathalie BrackeSofie StalmansKathelijne PeremansChristian BurvenichMartijn Risseeuw et al.

A1 Journal Article in BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE

Quality control of cationic cell-penetrating peptides

Sofie StalmansBert GevaertFrederick VerbekeMatthias D'HondtNathalie BrackeEvelien WynendaeleBart De Spiegeleer

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Regulatory development of geriatric medicines : to GIP or not to GIP?

Bart De SpiegeleerEvelien WynendaeleNathalie BrackeLieselotte VeryserLien TaevernierAgnes DegrooteSofie Stalmans

A1 Journal Article in AGEING RESEARCH REVIEWS

2015

Blood–brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins

Mathieu VerbekenEvelien WynendaeleElodie MauchaufféeNathalie BrackeSofie StalmansEngin BojnikSandor BenyheKathelijne PeremansIngeborgh PolisChristian Burvenich et al.

A1 Journal Article in PEPTIDES

Cell-penetrating peptides selectively cross the blood-brain barrier in vivo

Sofie StalmansNathalie BrackeEvelien WynendaeleBert GevaertKathelijne PeremansChristian BurvenichIngeborgh PolisBart De Spiegeleer

A1 Journal Article in PLOS ONE

Classification of peptides according to their blood-brain barrier influx

Sofie StalmansBert GevaertEvelien WynendaeleJoachim NielandtGuy De TréKathelijne PeremansChristian BurvenichBart De Spiegeleer

A1 Journal Article in PROTEIN AND PEPTIDE LETTERS

Exploring the chemical space of quorum sensing peptides

Evelien WynendaeleBert GevaertSofie StalmansFrederick VerbekeBart De Spiegeleer

A1 Journal Article in BIOPOLYMERS

Quorum sensing peptides selectively penetrate the blood-brain barrier

Evelien WynendaeleFrederick VerbekeSofie StalmansBert GevaertYorick JanssensChristophe Van De WieleKathelijne PeremansChristian BurvenichBart De Spiegeleer

A1 Journal Article in PLOS ONE

To what extent do cell-penetrating peptides selectively cross the blood-brain barrier?

Sofie StalmansBart De Spiegeleer

2014

An in silico approach for modelling T-helper polarizing iNKT cell agonists

Anton De SpiegeleerEvelien WynendaeleMatthias VandekerckhoveSofie StalmansMaxime BoucartNele Van Den NoortgateKoen VenkenSerge Van CalenberghSandrine AspeslaghDirk Elewaut

A1 Journal Article in PLOS ONE

Blood-brain barrier transport of short proline-rich antimicrobial peptides

Sofie StalmansEvelien WynendaeleNathalie BrackeDaniel KnappeRalf HoffmannKathelijne PeremansIngeborgh PolisChristian BurvenichBart De Spiegeleer

A1 Journal Article in PROTEIN AND PEPTIDE LETTERS

Derringer desirability and kinetic plot LC-column comparison approach for MS-compatible lipopeptide analysis

Matthias D'HondtFrederick VerbekeSofie StalmansBert GevaertEvelien WynendaeleBart De Spiegeleer

A2 Journal Article in JOURNAL OF PHARMACEUTICAL ANALYSIS

Development of geriatric medicines: to GIP or not to GIP?

Sofie StalmansNathalie BrackeBart De Spiegeleer

Development of peptide and protein based radiopharmaceuticals

Evelien WynendaeleNathalie BrackeSofie StalmansBart De Spiegeleer

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

Do cell-penetrating peptides cross the blood-brain barrier

Sofie StalmansEvelien WynendaeleNathalie BrackeBart De Spiegeleer

Exploration of the peptide drug space

Bert GevaertEvelien WynendaeleMathieu VerbekenMatthias D'HondtSofie StalmansKathelijne PeremansChristian BurvenichCatherine DelesalleBart De Spiegeleer

Flatworm models in pharmacological research: the importance of compound stability testing

Sofie StalmansMaxime WillemsEls AdriaensJean Paul RemonMatthias D'HondtBart De Spiegeleer

A1 Journal Article in REGULATORY TOXICOLOGY AND PHARMACOLOGY

How the exploration of the chemical space of cell-penetrating peptides helps to understand their functionality

Sofie StalmansEvelien WynendaeleBart De Spiegeleer

2013

A computational high-throughput screening approach of iNKT-agonists: a novel tool to find optimized iNKT cell ligands

Anton De SpiegeleerEvelien WynendaeleSofie StalmansNele Van Den NoortgateMatthias VandekerckhoveSerge Van CalenberghSandrine AspeslaghKoen VenkenDirk Elewaut

Chemical-functional diversity in cell-penetrating peptides

Sofie StalmansEvelien WynendaeleNathalie BrackeBert GevaertMatthias D'HondtKathelijne PeremansChristian BurvenichBart De Spiegeleer

A1 Journal Article in PLOS ONE

Quorumpeps database : chemical space, microbial origin and functionality of quorum sensing peptides

Evelien WynendaeleAntoon BronselaerJoachim NielandtMatthias D'HondtSofie StalmansNathalie BrackeFrederick VerbekeChristophe Van De WieleGuy De TréBart De Spiegeleer

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Reversed-phase fused-core HPLC modeling of peptides

Matthias D'HondtBert GevaertSofie StalmansSylvia Van DorpeEvelien WynendaeleKathelijne PeremansChristian BurvenichBart De Spiegeleer

A2 Journal Article in JOURNAL OF PHARMACEUTICAL ANALYSIS

2012

Blood-brain barrier modelling of bioactive peptides

Bart De SpiegeleerMatthias D'HondtSofie StalmansSylvia Van Dorpe

Brainpeps: the blood-brain barrier peptide database

Sylvia Van DorpeAntoon BronselaerJoachim NielandtSofie StalmansEvelien WynendaeleKurt AudenaertChristophe Van De WieleChristian BurvenichKathelijne PeremansHung Hsuchou et al.

A1 Journal Article in BRAIN STRUCTURE & FUNCTION

Exploring the Brainpeps database

Sofie StalmansMatthias D'HondtEvelien WynendaeleNathalie BrackeBart De Spiegeleer

Exploring the chemical-functional space of cell-penetrating peptides

Sofie StalmansEvelien WynendaeleBart De Spiegeleer

Receptor and blood-brain barrier characterisation of opioid peptides in drug research and early development

Bart De SpiegeleerSofie StalmansEvelien WynendaeleNathalie BrackeMathieu VerbekenKathelijne PeremansIngeborgh PolisChristian Burvenich

Receptor and blood-brain barrier characterization of opioid peptides in drug research and early development

Mathieu VerbekenSofie StalmansEvelien WynendaeleNathalie BrackeBert GevaertKathelijne PeremansIngeborgh PolisChristian BurvenichBart De Spiegeleer

Variation of the net charge, lipophilicity, and side chain flexibility in Dmt¹-DALDA: effect on opioid activity and biodistribution

Alexandre NovoaSylvia Van DorpeEvelien WynendaeleMariana SpeteaNathalie BrackeSofie StalmansCecilia BettiNga N ChungCarole LemieuxJohannes Zuegg et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY