Research Explorer

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Researcher

Sofie Roelandt

Publications & Research Data

Awards & Distinctions

10 Results

2025

A benchmark of DNA methylation deconvolution methods for tumoral fraction estimation using DecoNFlow

Edoardo GiuiliSofie Van de VeldeSam KintMaísa Renata Ferro Dos SantosLotte CornelliSofie RoelandtKathleen SchoofsRenske ImschootRuben Van PaemelLeander Meuris et al.

2024

A fast, affordable and minimally-invasive diagnostic test for Cancer of Unknown Primary (CUP) using DNA methylation profiling

Jilke De WildeRuben Van PaemelAndries De KokerSofie RoelandtSofie Van de VeldeNico CallewaertJo Van DorpeDavid CreytensBram De WildeKatleen De Preter

A1 Journal Article in LABORATORY INVESTIGATION

Defining the optimal setting for transcriptomic analyses on blood samples for response prediction in immunotherapy-treated NSCLC patients

Alvaro Marcos RubioSeoyeon OhSofie RoelandtDieter StevensEufra Van DammeKarim VermaelenKatleen De PreterCeline Everaert

A1 Journal Article in SCIENTIFIC REPORTS

Diagnosis of pediatric central nervous system tumors using methylation profiling of cfDNA from cerebrospinal fluid

Lotte CornelliRuben Van PaemelMaísa Renata Ferro Dos SantosSofie RoelandtLeen WillemsJelle VandersteeneEdward BaertLiselot MusNadine Van RoyBram De Wilde et al.

A1 Journal Article in CLINICAL EPIGENETICS

NBAtlas : a harmonized single-cell transcriptomic reference atlas of human neuroblastoma tumors

Noah BonineVittorio ZanzaniAnnelies Van HemelrykBavo VannesteChristian ZwickerTinne ThonéSofie RoelandtSarah-Lee BekaertJan KosterIsabelle Janoueix-Lerosey et al.

A1 Journal Article in CELL REPORTS

Therapy response monitoring in blood plasma from esophageal adenocarcinoma patients using cell-free DNA methylation profiling

Kathleen SchoofsMaísa Renata Ferro Dos SantosJilke De WildeSofie RoelandtSofie Van de VeldePhilippe DecruyenaereLeander MeurisOlivier ThasAnnouck PhilippronLieven Depypere et al.

A1 Journal Article in SCIENTIFIC REPORTS

2023

A harmonized single-cell transcriptomic atlas of human neuroblastoma

Noah BonineVittorio ZanzaniLiselot MusBavo VannesteChristian ZwickerTinne ThonéSofie RoelandtCécile ThirantAmira KramdiIsabelle Janoueix-Lerosey et al.

Deconvolution-based estimation of immune cell fractions in blood for immunotherapy response prediction in non-small cell lung cancer patients

Alvaro Marcos RubioCeline EveraertSofie RoelandtEufra Van DammeDieter StevensKarim VermaelenKatleen De Preter

2022

Cell type deconvolution as a strategy to develop a blood-based test for immunotherapy response prediction in lung cancer patients

Alvaro Marcos RubioCeline EveraertEufra Van DammeDieter StevensSofie RoelandtKarim VermaelenKatleen De Preter

Digital PCR-based evaluation of nucleic acid extraction kit performance for the co-purification of cell-free DNA and RNA

Jill DeleuKathleen SchoofsAnneleen DecockKimberly VerniersSofie RoelandtAngie DenolfJoke VerrethBram De WildeTom Van MaerkenKatleen De Preter et al.

A1 Journal Article in HUMAN GENOMICS