Research Explorer

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Researcher

Sofie Martens

Awards & Distinctions

11 Results

2022

Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state

Farzaneh GhazaviJelle HuysentruytJordy De ConinckStephanie KourulaSofie MartensBehrouz HassanniaTim WartewigTatyana DivertRia RoelandtBastian Popper et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice

Sofie MartensNozomi TakahashiGillian BlanckeNiels VandammeHanne VerschuereTatyana DivertMarnik VuylstekeGeert BerxPeter Vandenabeele

A1 Journal Article in CELL DEATH & DISEASE

2021

MLKL in cancer : more than a necroptosis regulator

Sofie MartensJolien BridelanceRia RoelandtPeter VandenabeeleNozomi Takahashi

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2020

Inhibitors targeting RIPK1/RIPK3 : old and new drugs

Sofie MartensSam HofmansWim DeclercqKoen AugustynsPeter Vandenabeele

A1 Journal Article in TRENDS IN PHARMACOLOGICAL SCIENCES

Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death

Sandy Adjemian CataniTeodora-Eugenia OlteanSofie MartensBartosz WiernickiVera GoossensTom Vanden BergheBenjamin CappeMaria LadikFranck RiquetLiesbeth Heyndrickx et al.

A1 Journal Article in CELL DEATH & DISEASE

2019

Necroptotic proteins in diseases : targeting RIP kinases in inflammatory disorders and exploring the role of MLKL in melanoma development

Sofie MartensPeter VandenabeeleNozomi TakahashiVera Goossens

2018

RIPK1-dependent cell death : a novel target of the Aurora kinase inhibitor Tozasertib (VX-680)

Sofie MartensVera GoossensLars DevisscherSam HofmansPolien ClaeysMarnik VuylstekeNozomi TakahashiKoen AugustynsPeter Vandenabeele

A1 Journal Article in CELL DEATH & DISEASE

Tozasertib analogues as inhibitors of necroptotic cell death

Sam HofmansLars DevisscherSofie MartensDries Van RompaeyKenneth GoossensTatyana DivertWim NerinckxNozomi TakahashiHans De WinterPieter Van der Veken et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

2017

Ionizing radiation-induced cell death

Sandy Adjemian CataniKatrien VandecasteeleSofie MartensBartosz WiernickiTania Love AaesDmitri KryskoPeter Vandenabeele

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells

Friederike FeldmannBarbara SchenkSofie MartensPeter VandenabeeleSimone Fulda

A1 Journal Article in ONCOTARGET

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury

Sofie MartensManhyung JeongWulf TonnusFriederike FeldmannSam HofmansVera GoossensNozomi TakahashiJan Hinrich BraesenEun-Woo LeePieter Van der Veken et al.

A1 Journal Article in CELL DEATH & DISEASE