Research Explorer

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Researcher

Sofie Desmet

Awards & Distinctions

12 Results

2020

Nuclear receptor crosstalk : defining the mechanisms for therapeutic innovation

Karolien De BosscherSofie DesmetDorien ClarisseEva Estébanez-PerpiñaLuc Brunsveld

A1 Journal Article in NATURE REVIEWS ENDOCRINOLOGY

2018

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De Cauwer et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular actions of PPARα in lipid metabolism and inflammation

Nadia BougarneBasiel WeyersSofie DesmetJulie DeckersDavid W RayBart StaelsKarolien De Bosscher

A1 Journal Article in ENDOCRINE REVIEWS

Study of the transcriptional crosstalk between metabolic nuclear receptors

Sofie DesmetKarolien De BosscherJan Tavernier

2017

Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Sofie DesmetNadia BougarneLaura Van MoortelLode De CauwerJonathan ThommisM VuylstekeDariusz RatmanR HoutmanJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Ioanna PettaNadia BougarneJolien VandewalleLien DejagerSofie VandevyverMarlies BallegeerSofie DesmetJonathan ThommisLode De CauwerSam Lievens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Glucocorticoid receptors : finding the middle ground

Sofie DesmetKarolien De Bosscher

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

2014

Cofactor profiling of the glucocorticoid receptor from a cellular environment

Sofie DesmetLien DejagerDorien ClarisseJonathan ThommisDiana MelchersNiek BastiaensenRob RuijtenbeekIlse BeckClaude LibertRenée Houtman et al.

Bookchapter in Steroid receptors : methods and protocols

Determining the cofactor profile of the glucocorticoid receptor in lymphoid malignancies using MARCoNI

Dorien ClarisseSofie DesmetJonathan ThommisIlse BeckKarolien De Bosscher

Determining the coregulator profile of the endogenous glucocorticoid receptor in lymphoid malignancies using MARCoNI

Dorien ClarisseDariusz RatmanSofie DesmetJonathan ThommisRené HoutmanKarolien De BosscherIlse Beck

The increasing complexity of glucocorticoid receptor signaling and regulation

Sofie DesmetIlse BeckNadia BougarneDorien ClarisseJulie DeckersDariusz RatmanJan TavernierKarolien De Bosscher

A2 Journal Article in PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE

2013

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

Ilse BeckZuzanna DrebertRuben Hoya-AriasAli A BaharMichael DevosDorien ClarisseSofie DesmetNadia BougarneBart RuttensValerie Gossye et al.

A1 Journal Article in PLOS ONE