Research Explorer

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Researcher

Sofia Zanotti

12 Results

2022

Cellular profiling reveals molecular determinants and vulnerabilities of neuroblastoma

Sofia ZanottiWinnok H. De VosFranki Speleman

Cellular senescence in neuroblastoma

Sofia ZanottiBieke DecaestekerSuzanne VanhauwaertBram De WildeWinnok De VosFranki Speleman

A1 Journal Article in BRITISH JOURNAL OF CANCER

RRM2 enhances MYCN driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Lisa DepestelCarolina de Carvalho NunesLiselot MusIris NelenLouis DelhayeKaylee KellerVolodimir OlexioukFanny De VloedEllen SandersAline Eggermont et al.

2021

MYCN-induced nucleolar stress drives an early senescence-like transcriptional program in hTERT-immortalized RPE cells

Sofia ZanottiSuzanne VanhauwaertChristophe Van NesteVolodimir OlexioukJolien Van LaereMarlies VerschuurenJoni Van der MeulenLiselot MusKaat DurinckLaurentijn Tilleman et al.

A1 Journal Article in SCIENTIFIC REPORTS

2019

MYCN activation in hTERT immortalized RPE cells as model for oncogene induced senescence

Sofia ZanottiBieke DecaestekerSuzanne VanhauwaertMichael D HogartyVolodimir OlexioukKaat DurinckWinnok De VosFranki Speleman

2018

Comprehensive pharmacological profiling in neuroblastoma cell lines using Deep Coverage Microscopy (DCM)

Sofia ZanottiMarlies VerschuurenKaat DurinckFranki SpelemanWinnok De Vos

Comprehensive pharmacological profiling in neuroblastoma cell lines using Deep Coverage Microscopy (DCM)

Sofia ZanottiMarlies VerschuurenKaat DurinckFranki SpelemanWinnok De Vos

MYCN activation in hTERT immortalized RPE cells as a model for oncogene induced senescence

Sofia ZanottiMarlies VerschuurenMichael D HogartyKaat DurinckWinnok De VosFranki Speleman

MYCN activation in hTERT immortalized RPE cells as model for oncogene induced senescence

Sofia ZanottiBieke DecaestekerMarlies VerschuurenMichael D HogartyKaat DurinckWinnok De VosFranki Speleman

The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype

Carolina de Carvalho NunesKaat DurinckLisa DepestelSiebe LoontiensLouis DelhayeSofia ZanottiEmmy DolmanAline EggermontBieke DecaestekerPauline Depuydt et al.

2017

Comprehensive pharmacological profiling in neuroblastoma cell lines using deep coverage microscopy

Sofia ZanottiWinnok De VosFranki Speleman

2016

Comprehensive pharmacological profiling in neuroblastoma cell lines using high-throughput microscopy

Sofia ZanottiWinnok De VosFranki Speleman