Research Explorer

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Researcher

Siska Croubels

Publications & Research Data

Awards & Distinctions

678 Results

2026

Optimization and validation of a targeted high-throughput UHPLC-MS/MS method for the analysis of multiple mycotoxins in chicken serum, egg yolk and white

Tadele Kabeta YadessaSiegrid De BaereSiska CroubelsGunther Antonissen

A1 Journal Article in MYCOTOXIN RESEARCH

Pharmacokinetics and Withdrawal Time of Doxycycline in Snakehead (Channa striata) Following Oral Medication

Nguyen Quoc ThinhHan Chi ThienMathias DevreeseSiska CroubelsMasashi MaitaTran Minh Phu

U Journal Article in Journal of Fish Diseases

2025

A low dose of berberine is metabolized in weaned piglets without major changes to gut morphology or gut microbiota

Christina MouchtoglouMarc CherletTessa DehauMarijke AluweRichard DucatelleEvy GoossensSiska CroubelsFilip Van Immerseel

A1 Journal Article in ANIMALS

Absolute oral bioavailability, quantitative toxicokinetics and metabolite profiling of alternariol and alternariol monomethyl ether in pigs

Danica den HollanderSiegrid De BaereCelestien HolvoetMathias DevreeseGunther AntonissenAnn MartensKristel DemeyereKris AudenaertEvelyne MeyerSiska Croubels

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy

Phillis Emelda OchiengDavid KemboiSheila OkothSiegrid De BaereEtienne CavalierErastus Kang’etheBarbara DoupovecJames GathumbiMarie-Louise ScippoGunther Antonissen et al.

A1 Journal Article in MYCOTOXIN RESEARCH

Cellular deconstruction of the human skeletal muscle microenvironment identifies an exercise-induced histaminergic crosstalk

Thibaux Van der StedeAlexia Van de LoockGuillermo TurielCamilla HansenAndrea Tamariz-EllemannMax UllrichEline LievensJan SpaasNurten YigitJasper Anckaert et al.

A1 Journal Article in CELL METABOLISM

Consistent phenological advancement of Common Toad migration in response to climate change in Flanders, Belgium

Ellen BlommeFemke BatsleerHans MatheveDominique VerbelenAn MartelSiska CroubelsFrank PasmansDries Bonte

A1 Journal Article in AMPHIBIA-REPTILIA

Doxycycline pharmacokinetics and tissue depletion in striped catfish (Pagasianodon hypophthalmus) after oral administration

Pham Quang VinhNguyen Quoc ThinhMathias DevreeseSiska CroubelsDang Thi Hoang OanhAnders DalsgaardMasashi MaitaTran Minh Phu

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Impact of veterinary drug and pesticide residues on populations of the European common toad (Bufo Bufo)

Sarah DevliegereSiegrid De BaereTess GoessensAndrea BarbiEllen BlommePieter VantieghemAn MartelDries BonteFrank PasmansLynn Vanhaecke et al.

In-vitro experiments suggest Ixodes ricinus nymphs prefer blood with Borrelia infection and low glucocorticoid levels

Tosca VanroyBram CatfolisElin VerbruggheKris VerheyenLuc LensDiederik StrubbeFrank PasmansAn MartelSiska CroubelsMarc Cherlet et al.

U Journal Article in Experimental Parasitology

International interlaboratory study to normalize liquid chromatography-based mycotoxin retention times through implementation of a retention index system

M.J. KelmanJ. B. RenaudP. McCarronS. HoogstraW. ChowJ. WangE. VargaA. PatriarcaA. Medina VayaLia Visintin et al.

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Pharmacokinetics, pharmacodynamics and depletion of florfenicol applied in white leg shrimp (Litopenaeus vannamei) aquaculture and impact on shrimp hepatopancreas histology

Thi Kim Duyen HuynhQuoc Thinh NguyenMarie-Louise ScippoThi Hoang Oanh DangMathias DevreeseCaroline DounySiska CroubelsQuoc Viet LeMinh Phu Tran

A1 Journal Article in FISHES

Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing

Pierre‐Louis ToutainAlain Bousquet‐MelouAude A. FerranBéatrice B. RoquesJérôme R. E. del CastilloPeter LeesSiska CroubelsEric BousquetLudovic Pelligand

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Proportion of forest surrounding breeding habitat predicts newt condition and fluctuating asymmetry

Leni LammensTosca VanroyNancy De SaeyerAn MartelLander BaetenLuc LensDiederik StrubbeKris VerheyenSiska CroubelsPeter Goethals et al.

A1 Journal Article in AMPHIBIA-REPTILIA

Targeted high-throughput UHPLC-MS/MS methodology to quantify cholecalciferol and its major metabolites calcidiol and calcitriol in serum, tissues and egg yolk of broiler chickens and laying hens

Siegrid De BaereVeerle HautekietWouter Van der VekenRobert CornezSiska Croubels

A1 Journal Article in MICROCHEMICAL JOURNAL

The impact of agricultural contaminants on populations of the European common toad

Sarah DevliegereSiegrid De BaereTess GoessensAndrea BarbiEllen BlommePieter VantieghemAn MartelDries BonteFrank PasmansLynn Vanhaecke et al.

Widespread anticoagulant rodenticide exposure in hedgehogs and their prey: prevalence, distribution and hedgehogs’ health implications

Valérie MiserezNaomi TerriereEllen BlommeMarc CherletSiska CroubelsSofie De BruyckereKatleen HermansVeronique SaeyElin VerbruggheFrank Pasmans et al.

U Journal Article in Science of The Total Environment

2024

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Céline Van DenderSteven TimmermansVille PaakinahoTineke VanderhaeghenJolien VandewalleMaarten ClaesBruno GarciaBart RomanJan De WaeleSiska Croubels et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Actinobacteria as promising biocontrol agents for in vitro and in planta degradation and detoxification of Zearalenone

Larissa De TroyerNoémie De ZutterSarah De SaegerFrédéric DumoulinSiska CroubelsSiegrid De BaereLeen De GelderKris Audenaert

A1 Journal Article in TOXINS

Application of preclinical juvenile animal models

Eline HermansJaan ToelenDomenico VentrellaLuc De SchaepdrijverKatie TurnerSiska CroubelsMathias Devreese

Bookchapter in Essentials of translational pediatric drug development : from past needs to future oportunities

Awareness of poultry farmers of interconnected health risks : a cross-sectional study on mycotoxins, biosecurity, and salmonellosis in Jimma, Ethiopia

Tadele Kabeta YadessaTadele TolosaAlamayo NagaraIlias ChantziarasSiska CroubelsFilip Van ImmerseelGunther Antonissen

A1 Journal Article in ANIMALS

Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

Fëllanza HalimiTineke VanderhaeghenSteven TimmermansSiska CroubelsClaude LibertJolien Vandewalle

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endotoxin translocation is increased in broiler chickens fed a fusarium mycotoxin-contaminated diet

Nicole ReisingerBarbara DoupovecTibor CzabanyFilip Van ImmerseelSiska CroubelsGunther Antonissen

A1 Journal Article in TOXINS

Exploration of cytochrome P450-related interactions between aflatoxin B1 and tiamulin in broiler chickens

Pan SunOrphélie LootensTadele Kabeta YadessaDiethard ReckelbusNatalia FurmanXingyuan CaoSuxia ZhangGunther AntonissenSiska CroubelsMarthe De Boevre et al.

A1 Journal Article in TOXINS

Influence of traditional dehulling on mycotoxin reduction and GC-HRTOF-MS metabolites profile of fermented maize products

Julianah Olayemi OdukoyaSarah De SaegerMarthe De BoevreGabriel Olaniran AdegokeFrank DevlieghereSiska CroubelsGunther AntonissenJohnson Oluwaseun OdukoyaPatrick Berka Njobeh

A1 Journal Article in HELIYON

Pharmacokinetics and withdrawal times of cefotaxime in white leg shrimp (Litopenaeus vannamei) after oral administration

Thi Kim Duyen HuynhMarie-Louise ScippoMathias DevreeseSiska CroubelsQuoc Thinh NguyenCaroline DounyThi Hoang Oanh DangQuoc Viet LeMinh Phu Tran

A1 Journal Article in FISHES-BASEL

Population pharmacokinetics of lisinopril in hypertensive children and adolescents with normal to mildly reduced kidney function

Louis SandraEva DegraeuwePauline De BruyneSiegrid De BaereSiska CroubelsJan Van BocxlaerAnn RaesJohan Vande WalleElke GasthuysAn Vermeulen

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children

Evelyn DhontTatjana Van Der HeggenEvelien SnauwaertJef WillemsSiska CroubelsJoris DelangheJan De WaeleRoos ColmanJohan Vande WallePeter De Paepe et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

Prenatal treprostinil improves pulmonary arteriolar hypermuscularization in the rabbit model of congenital diaphragmatic hernia

Felix R. De BieYannick ReginAntoine DuboisMarianna ScugliaTomohiro AraiEwout MuylleDavid BasurtoMarius ReginSiska CroubelsMarc Cherlet et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Quinolizidine alkaloids and phomopsin A in animal feed containing lupins : co-occurrence and carry-over into veal products

Sofie SchryversLiesbeth JacxsensSiska CroubelsSigrid VonckBram MiserezJet van de SteeneGraciele Necchi RohersMia Eeckhout

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Salicylic acid residues in products of animal origin

Ken HoubenPhilippe DelahautMarie-Louise ScippoEls DaeseleireSiska CroubelsBruno UrbainYvan VandenplasFrançois VerheggenNathalie Gillard

A4 Journal Article in FOOD RISK ASSESS EUROPE

Serum symmetric dimethylarginine in older dogs : reference interval and comparison of a gold standard method with the ELISA

Sofie MarynissenGreet JuniusEvi van den SteenLisbeth PatteetLuc DuchateauSiska CroubelsSylvie DaminetDominique Paepe

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

2023

A high dose of dietary berberine improves gut wall morphology, despite an expansion of enterobacteriaceae and a reduction in beneficial microbiota in broiler chickens

Tessa DehauMarc CherletSiska CroubelsFilip Van ImmerseelEvy Goossens

A1 Journal Article in MSYSTEMS

Acute balenine supplementation in humans as a natural carnosinase-resistant alternative to carnosine

Sarah de JagerAn VermeulenSiegrid De BaereThibaux Van der StedeEline LievensSiska CroubelsRalf JägerMartin PurpuraJan BourgoisWim Derave

A1 Journal Article in SCIENTIFIC REPORTS

Balancing health risks and benefits of red mangrove crab consumption

Andrée De CockMarie Anne Eurie ForioSiska CroubelsLuis Dominguez-GrandaLiesbeth JacxsensCarl LachatHeydi Roa-LopezJenny RualesVictoria ScheyvaertsMichelle Carolina Solis Hidalgo et al.

Berberine-microbiota interplay : orchestrating gut health through modulation of the gut microbiota and metabolic transformation into bioactive metabolites

Tessa DehauMarc CherletSiska CroubelsMichiel Van de VlietEvy GoossensFilip Van Immerseel

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur

Sofie RutjensNick VereeckeJannes SauerSiska CroubelsMathias Devreese

A1 Journal Article in VETERINARY RESEARCH

Ceftiofur and cefquinome : the emergence and selection of antimicrobial resistance in the porcine gut microbiome

Sofie RutjensMathias DevreeseSiska Croubels

Comparative toxicokinetics of Alternaria mycotoxins in pigs as a surrogate animal model for humans

Diethard ReckelbusDanica den HollanderCelestien HolvoetSiegrid De BaereMathias DevreeseKristel DemeyereNoémie De ZutterKris AudenaertEvelyne MeyerSiska Croubels

Development of high-throughput sample preparation procedures for the quantitative determination of aflatoxins in biological matrices of chickens and cattle using UHPLC-MS/MS

Siegrid De BaerePhillis Emelda OchiengDavid C. KemboiMarie-Louise ScippoSheila OkothJohanna F. LindahlJames K. GathumbiGunther AntonissenSiska Croubels

A1 Journal Article in TOXINS

Effects of aflatoxins and fumonisins, alone or in combination, on performance, health, and safety of food products of broiler chickens, and mitigation efficacy of bentonite and fumonisin esterase

Phillis Emelda OchiengSiska CroubelsDavid KemboiSheila OkothSiegrid De BaereEtienne CavalierErastus Kang’etheJohannes FaasBarbara DoupovecJames Gathumbi et al.

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Efficacy of bentonite and fumonisin esterase in mitigating the effects of aflatoxins and fumonisins in two Kenyan cattle breeds

David KemboiGunther AntonissenPhillis Emelda OchiengSiska CroubelsSiegrid De BaereMarie-Louise ScippoSheila OkothErastus KangetheJohannes FaasBarbara Doupovec et al.

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Extensive profiling of histidine‐containing dipeptides reveals species‐ and tissue‐specific distribution and metabolism in mice, rats, and humans

Thibaux Van der StedeJan SpaasSarah de JagerJana De BrandtCamilla HansenJan StautemasBjarne VercammenSiegrid De BaereSiska CroubelsCharles‐Henri Van Assche et al.

A1 Journal Article in ACTA PHYSIOLOGICA

Health risk-benefit assessment of the commercial red mangrove crab : implications for a cultural delicacy

Andrée De CockMarie Anne Eurie ForioSiska CroubelsLuis Dominguez-GrandaLiesbeth JacxsensCarl LachatHeydi Roa-LópezJenny RualesVictoria ScheyvaertsMichelle Carolina Solis Hidalgo et al.

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Het voorschrijven van humane geneesmiddelen en magistrale bereidingen in de diergeneeskundige praktijk

Phaedra DolfeynMathias DevreeseSiska Croubels

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Homogeneity, stability, interactions, and cross-contamination of antibacterial drugs mixed into drinking water for group treatment in broilers

Despoina GeorgakiGunther AntonissenMathias DevreeseJeroen DewulfPatrick De BackerJelle LambrechtIlias ChantziarasSiska Croubels

Iohexol is an intestinal permeability marker in broilers under coccidiosis challenge

Katrien RysmanVenessa EeckhautSiska CroubelsBrecht MaertensFilip Van Immerseel

A1 Journal Article in POULTRY SCIENCE

Mycotoxin reduction and metabolite profiles of ogi produced using traditional fermentation methods

Julianah Olayemi OdukoyaSarah De SaegerMarthe De BoevreGabriel Olaniran AdegokeFrank DevlieghereSiska CroubelsGunther AntonissenOluwafemi Ayodeji AdeboSefater GbashiJohnson Oluwaseun Odukoya et al.

A2 Journal Article in FOOD HYDROCOLLOIDS FOR HEALTH

Mycotoxins in kenyan poultry feeds : occurrence and use of bentonite and fumonisin esterase as a sustainable mitigation strategy to reduce effects of aflatoxins and fumonisins in broiler chicken and layer hens production

Phillis Emelda OchiengMarie-Louise ScippoSiska CroubelsSheila Okoth

No effect of acute balenine supplementation on maximal and submaximal exercise performance in recreational cyclists

Sarah de JagerStefaan Van DammeSiegrid De BaereSiska CroubelsRalf JägerMartin PurpuraEline LievensJan BourgoisWim Derave

A1 Journal Article in INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Obesity promotes fumonisin B1 hepatotoxicity

Léonie DopavoguiMarion RégnierArnaud PolizziQuentin PonchonSarra SmatiWendy KlementFrédéric LasserreCéline LukowiczYannick LippiAnne Fougerat et al.

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Pharmacokinetics and depletion of florfenicol in striped catfish Pangasianodon hypophthalmus after oral administration

Quang Vinh PhamQuoc Thinh NguyenMathias DevreeseSiska CroubelsThi Hoang Oanh DangAnders DalsgaardMasashi MaitaMinh Phu Tran

A1 Journal Article in FISHERIES SCIENCE

Porcine ear necrosis : characterization of lesions and associated pathogens

Mateusz MalikKoen ChiersSebastiaan TheunsNick VereeckeIlias ChantziarasSiska CroubelsDominiek Maes

A1 Journal Article in VETERINARY RESEARCH

Qualitative risk assessment of homogeneity, stability, and residual concentrations of antimicrobials in medicated feed and drinking water in pig rearing

Despoina GeorgakiFemke VandaelHelena Cardoso de Carvalho FerreiraMaria-Eleni FilippitziPatrick De BackerMathias DevreeseJeroen DewulfSiska Croubels

A1 Journal Article in BMC VETERINARY RESEARCH

The pig as a translational animal model to explore a new concept in the treatment of sepsis, today's largest unmet medical need

Fëllanza HalimiCharlotte CuypersBruna AlonsoEline HermansDiethard ReckelbusJolien VandewalleB. GarciaA. HerpainTineke VanderhaeghenCéline Van Dender et al.

The pig as a translational animal to explore a new concept in the treatment of sepsis, today's largest unmet medical need

Fëllanza HalimiCharlotte CuypersBruna AlonsoEline HermansDiethard ReckelbusJolien VandewalleBruno GarciaAntoine HerpainTineke VanderhaeghenCéline Van Dender et al.

Widespread triazole pesticide use affects infection dynamics of a global amphibian pathogen

Andrea BarbiTess GoessensDiederik StrubbeArne DeknockRobby Van LeeuwenbergNiels De TroyerElin VerbruggheMark GreenerSiegrid De BaereLuc Lens et al.

A1 Journal Article in ECOLOGY LETTERS

2022

Agricultural contaminants in amphibian breeding ponds : occurrence, risk and correlation with agricultural land use

Tess GoessensSiegrid De BaereArne DeknockNiels De TroyerRobby van LeeuwenbergAn MartelFrank PasmansPeter GoethalsLuc LensPieter Spanoghe et al.

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Applicability of food web interactions within aquatic ecosystems for biological control of amphibian chytridiomycosis

Arne DeknockPeter GoethalsSiska CroubelsFrank Pasmans

Berberrubine, a berberine-derived metabolite, is produced by the gut microbiota and improves broiler gut health

Tessa DehauMichiel Van de VlietMarc CherletSiska CroubelsEvy GoossensFilip Van Immerseel

Berberrubine, a berberine-derived metabolite, is produced by the gut microbiota and improves gut health

Tessa DehauMichiel Van de VlietMarc CherletSiska CroubelsEvy GoossensFilip Van Immerseel

Cytotoxic effects of alternariol, alternariol monomethyl-ether, and tenuazonic acid and their relevant combined mixtures on human enterocytes and hepatocytes

Danica den HollanderCelestien HolvoetKristel DemeyereNoémie De ZutterKris AudenaertEvelyne MeyerSiska Croubels

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Efficacy of fumonisin esterase in piglets as animal model for fumonisin detoxification in humans : pilot study comparing intraoral to intragastric administration

Kaat NeckermannGunther AntonissenBarbara DoupovecDian SchatzmayrJames GathumbiVéronique DelcenserieSilvio UhligSiska Croubels

A1 Journal Article in TOXINS

Essential descriptors for mycotoxin contamination data in food and feed

Addisalem Mesfin MuhiyeCarl LachatArnau Vidal CorominasSiska CroubelsGeert HaesaertMelody NdemeraSheila OkothTefera BelachewMarthe De BoevreSarah De Saeger et al.

A1 Journal Article in FOOD RESEARCH INTERNATIONAL

Hepatic peroxisome proliferator-activated receptor alpha dysfunction in porcine septic shock

Jolien VandewalleBruno GarciaSteven TimmermansTineke VanderhaeghenLise Van WyngeneMelanie EggermontHester DufoorCéline Van DenderFëllanza HalimiSiska Croubels et al.

A1 Journal Article in CELLS

Impact of heavy metal exposure on biological control of a deadly amphibian pathogen by zooplankton

Arne DeknockFrank PasmansRobby van LeeuwenbergSarah Van PraetNiels De TroyerTess GoessensLeni LammensStijn BruneelLuc LensAn Martel et al.

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

Influence of nixtamalization cooking ingredients on the minerals composition of nixtamalized maize and sorghum

Julianah Olayemi OdukoyaSarah De SaegerMarthe De BoevreGabriel Olaniran AdegokeKris AudenaertSiska CroubelsGunther AntonissenJohnson Oluwaseun OdukoyaPatrick Berka Njobeh

A1 Journal Article in JOURNAL OF CEREAL SCIENCE

Intestinal exposure to ceftiofur and cefquinome after intramuscular treatment and the impact of ceftiofur on the pig fecal microbiome and resistome

Sofie RutjensNick VereeckeWard De SpiegelaereSiska CroubelsMathias Devreese

A1 Journal Article in ANTIBIOTICS-BASEL

Intestinal exposure to ceftiofur and cefquinome after intramuscular treatment and the impact of ceftiofur on the pig fecal microbiome and resistome

Sofie RutjensNick VereeckeWard De SpiegelaereSiska CroubelsMathias Devreese

Machine learning-aided design of composite mycotoxin detoxifier material for animal feed

Giulia Lo DicoSiska CroubelsVerónica CarcelénMaciej Haranczyk

A1 Journal Article in SCIENTIFIC REPORTS

Maximizing laboratory production of aflatoxins and fumonisins for use in experimental animal feeds

Phillis Emelda OchiengDavid C. KemboiMarie-Louise ScippoJames K. GathumbiErastus KangetheBarbara DoupovecSiska CroubelsJohanna F. LindahlGunther AntonissenSheila Okoth

A1 Journal Article in MICROORGANISMS

Possible mechanisms of the interplay between drugs and mycotoxins : is there a possible impact?

Orphélie LootensAn VermeulenSiska CroubelsSarah De SaegerJan Van BocxlaerMarthe De Boevre

A1 Journal Article in TOXINS

Reliability of glomerular filtration rate estimating formulas compared to iohexol plasma clearance in critically ill children

Evelyn DhontCharlotte WindelsEvelien SnauwaertTatjana Van Der HeggenAnnik de JaegerLaura DhondtJoris DelangheSiska CroubelsJohan Vande WallePeter De Paepe et al.

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

Risk factors of augmented renal clearance in critically ill children using iohexol clearance for renal function assessment

Evelyn DhontTatjana Van Der HeggenEvelien SnauwaertJef WillemsSiska CroubelsJoris DelangheJohan Vande WallePeter De PaepePieter De Cock

Tackling mycotoxin dangers in human foods using in vitro and in vivo animal models : mitigation of aflatoxins and fumonisins

Kaat NeckermannSiska CroubelsVéronique DelcenserieSilvio UhligJames Gathumbi

The ergogenic effect of acute carnosine and anserine supplementation : dosing, timing, and underlying mechanism

Sarah de JagerLaura BlancquaertThibaux Van der StedeEline LievensSiegrid De BaereSiska CroubelsEttore GilardoniLuca G. RegazzoniGiancarlo AldiniJan Bourgois et al.

A1 Journal Article in JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION

2021

Accuracy of creatinine-based and cystatin c-based eGFR formulas compared to plasma iohexol clearance in children after cardio-pulmonary bypass

Evelyn DhontCharlotte WindelsANNIK DE JAEGERSiska CroubelsJohan Vande WallePeter De PaepePieter De Cock

Accuracy of creatinine-based and cystatin C-based eGFR formulas compared to plasma iohexol clearance in children after cardio-pulmonary bypass

Evelyn DhontC. WindelsANNIK DE JAEGERSiska CroubelsJohan Van de WallePeter De PaepePieter De Cock

Accuracy of renal function estimating equations compared to iohexol clearance in critically ill children

Evelyn DhontCharlotte WindelsTatjana Van Der HeggenJohan Vande WalleSiska CroubelsSiegrid De BaerePeter De PaepePieter De Cock

Accuracy of renal function estimating equations compared to iohexol clearance in critically ill children

Evelyn DhontCharlotte WindelsTatjana Van Der HeggenJohan Vande WalleSiska CroubelsSiegrid De BaerePeter De PaepePieter De Cock

Agricultural contaminants in freshwater ecosystems and disposition of fungicides in amphibians

Tess GoessensSiska CroubelsPeter GoethalsLuc LensFrank Pasmans

Alternative food sources interfere with removal of a fungal amphibian pathogen by zooplankton

Arne DeknockFrank PasmansRobby van LeeuwenbergSarah Van PraetStijn BruneelLuc LensSiska CroubelsAn MartelPeter Goethals

A1 Journal Article in JOURNAL OF APPLIED ECOLOGY

Applied research note : biomonitoring of mycotoxins in blood serum and feed to assess exposure of broiler chickens

Danica den HollanderSiska CroubelsMarianne LauwersNele CaekebekeMoniek RingenierFien De MeyerN. ReisingerFilip Van ImmerseelJeroen DewulfGunther Antonissen

A1 Journal Article in JOURNAL OF APPLIED POULTRY RESEARCH

Bacterial enrichment cultures biotransform the mycotoxin deoxynivalenol into a novel metabolite toxic to plant and porcine cells

Ilse VanhoutteCaroline De TenderKristel DemeyereMohamed Fathi AbdallahSarah OmmeslagPieter VermeirSarah De SaegerJane DebodeEvelyne MeyerSiska Croubels et al.

A1 Journal Article in TOXINS

Description of plasma penicillin G concentrations after intramuscular injection in double-muscled cows to optimize the timing of antibiotherapy for Caesarean section

Salem DjebalaSiska CroubelsMarc CherletLudovic MartinelleDamien ThiryNassim MoulaArnaud SarteletPhilippe Bossaert

A1 Journal Article in VETERINARY SCIENCES

Development and validation of liquid chromatography-tandem mass spectrometry methods for the quantification of cefquinome, ceftiofur, and desfuroylceftiofuracetamide in porcine feces with emphasis on analyte stability

Sofie RutjensSiska CroubelsSiegrid De BaereMathias Devreese

A1 Journal Article in MOLECULES

Dietary exposure assessment and risk characterization of citrinin and ochratoxin A in Belgium

Celine MeerpoelArnau Vidal CorominasMirjana AndjelkovicMarthe De BoevreEmmanuel K. TangniBart HuybrechtsMathias DevreeseSiska CroubelsSarah De Saeger

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Effect of selected cooking ingredients for nixtamalization on the reduction of Fusarium mycotoxins in maize and Sorghum

Julianah Olayemi OdukoyaSarah De SaegerMarthe De BoevreGabriel Olaniran AdegokeKris AudenaertSiska CroubelsGunther AntonissenKarel VermeulenSefater GbashiPatrick Berka Njobeh

A1 Journal Article in TOXINS

Ergogenic effect of pre-exercise chicken broth ingestion on a high-intensity cycling time-trial

Silvia BarbaresiLaura BlancquaertZoran NikolovskiSarah de JagerMathew WilsonInge EveraertSiegrid De BaereSiska CroubelsStefaan De SmetN. Tim Cable et al.

A1 Journal Article in JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION

Evaluation of serum lidocaine/monoethylglycylxylidide concentration to assess shunt closure in dogs with extrahepatic portosystemic shunts

Nausikaa DevriendtGonçalo SerranoSiska CroubelsEmmelie StockEva VandermeulenDominique PaepeJennifer von LucknerHilde De Rooster

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

Exploratory real-time kinetic analysis of the cytotoxicity induced by maize silage mycotoxins in a calf intestinal epithelial cell line

S. DebevereKristel DemeyereN. ReisingerJ. FaasGeert HaesaertVeerle FievezSiska CroubelsEvelyne Meyer

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

Multi-mycotoxin contamination of maize silages in Flanders, Belgium : monitoring mycotoxin levels from seed to feed

Jonas VandickeKATRIEN DE VISSCHEREMaarten AmeyeSiska CroubelsSarah De SaegerKris AudenaertGeert Haesaert

A1 Journal Article in TOXINS

Multi-residue analysis of 20 mycotoxins including major metabolites and emerging mycotoxins in freshwater using UHPLC-MS/MS and application to freshwater ponds in flanders, Belgium

Tess GoessensSiegrid De BaereNiels De TroyerArne DeknockPeter GoethalsLuc LensFrank PasmansSiska Croubels

A1 Journal Article in ENVIRONMENTAL RESEARCH

Mycotoxins in poultry feed and feed ingredients from Sub-Saharan Africa and their impact on the production of broiler and layer chickens : a review

Phillis Emelda OchiengMarie-Louise ScippoDavid KemboiSiska CroubelsSheila OkothErastus K. Kang’etheBarbara DoupovecJames K. GathumbiJohanna F. LindahlGunther Antonissen

A1 Journal Article in TOXINS

Perioperative pharmacokinetics and pharmacodynamics of meloxicam in emus (Dromaius novaehollandiae) of different age groups using nonlinear mixed effect modelling

Diego CastineirasLucy ArmitageLuís Pardon LamasSiegrid De BaereSiska CroubelsLudovic Pelligand

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Persecution of birds of prey in Flanders : a retrospective study 2011-19

An GarmynLieze RouffaerTom RoggemanMarc VerlindenKatleen HermansMarleen CoolsMark Van den MeersschautSiska CroubelsAn Martel

A1 Journal Article in JOURNAL OF WILDLIFE DISEASES

Persecution of birds of prey in Flanders between 2011-2019 : a retrospective study

An GarmynLieze RouffaerTom RoggemanMarc VerlindenKatleen HermansMarleen CoolsMark Van Den MeersschautSiska CroubelsAn Martel

Porcine ear necrosis

Mateusz MalikKoen ChiersFilip BoyenSiska CroubelsDominiek Maes

A1 Journal Article in VETERINARY JOURNAL

Porcine ear necrosis in weaned piglets : prevalence and impact on daily weight gain

Mateusz MalikAlexandra SchoosIlias ChantziarasDries DonkersSiska CroubelsBarbara DoupovecDominiek Maes

A1 Journal Article in PORCINE HEALTH MANAGEMENT

The development of a juvenile porcine augmented renal clearance model through continuous infusion of lipopolysaccharides : an exploratory study

Laura DhondtSiska CroubelsRobin TemmermanPieter De CockEvelyne MeyerWim Van Den BroeckPeter De PaepeMathias Devreese

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

The efficacy and effect on gut microbiota of an aflatoxin binder and a fumonisin esterase using an in vitro simulator of the human intestinal microbial ecosystem (SHIME®)

Kaat NeckermannGregor ClausSiegrid De BaereGunther AntonissenSarah LebrunCéline GemmiBernard TaminiauCaroline DounyMarie-Louise ScippoDian Schatzmayr et al.

A1 Journal Article in FOOD RESEARCH INTERNATIONAL

The ergogenicity of acute carnosine and anserine supplementation : the search for an underlying mechanism

Sarah de JagerLaura BlancquaertEline LievensSiegrid De BaereE. GilardoniL RegazzoniSiska CroubelsG. AldiniWim Derave

Unraveling the contribution of fluid therapy to the development of augmented renal clearance in a piglet model

Laura DhondtSiska CroubelsPeter De PaepeKlara GoethalsPieter De CockMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Volumetric absorptive microsampling as alternative sampling technique for renal function assessment in the paediatric population using iohexol

Laura DhondtSiska CroubelsPieter De CockEvelyn DhontSiegrid De BaerePeter De PaepeMathias Devreese

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2020

A review of the impact of mycotoxins on dairy cattle health : challenges for food safety and dairy production in Sub-Saharan Africa

David Chebutia KemboiGunther AntonissenPhillis Emelda OchiengSiska CroubelsSheila OkothErastus K KangetheJohannes FaasJohanna F LindahlJames K Gathumbi

A1 Journal Article in TOXINS

A study of carry-over and histopathological effects after chronic dietary intake of citrinin in pigs, broiler chickens and laying hens

Celine MeerpoelArnau Vidal CorominasEmmanuel K. TangniBart HuybrechtsLiesbeth CouckRiet De RyckeLobke De BelsSarah De SaegerWim Van Den BroeckMathias Devreese et al.

A1 Journal Article in TOXINS

Age-related differences in toxicokinetics of modified fusarium mycotoxins in the juvenile pig as a human paediatric surrogate model

Amelie CatteuwSiska CroubelsMathias DevreeseSarah De Saeger

Calcination improves the in vivo efficacy of a montmorillonite clay to bind aflatoxin G1 in broiler chickens : a toxicokinetic approach

Roua RejebSiegrid De BaereMathias DevreeseRichard DucatelleSiska CroubelsMadiha Hadj AyedAchraf GhorbalGunther Antonissen

A1 Journal Article in TOXINS

Comparative pharmacokinetics of imepitoin after oral and rectal administration in healthy dogs

Valentine MartléMathias DevreeseSaskia RauchLuc Van HamSiska CroubelsValérie VanhoorneChris VervaetSofie Bhatti

A1 Journal Article in VETERINARY JOURNAL

Comparative toxicokinetics of Fusarium mycotoxins in pigs and humans

Wim SchelstraeteMathias DevreeseSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens

Celine MeerpoelArnau Vidal CorominasBart HuybrechtsEmmanuel K. TangniSarah De SaegerSiska CroubelsMathias Devreese

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Conventional pig as animal model for human renal drug excretion processes : unravelling the porcine renal function by use of a cocktail of exogenous markers

Laura DhondtSiska CroubelsPeter De PaepeSteven C. WallisSaurabh PandeyJason A. RobertsJeffrey LipmanPieter De CockMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Development and validation of a rapid liquid chromatography-tandem mass spectrometry method for quantification of cefquinome, ceftiofur and its active metabolite, desfuroylceftiofur, in porcine plasma

Sofie RutjensSiska CroubelsMarc CherletMathias Devreese

Enantiomer specific pharmacokinetics of ibuprofen in preterm neonates with patent ductus arteriosus

Aline G.J. EngbersRobert B. FlintSwantje VöllerJohan C.A. de KlerkIrwin K.M. ReissPeter AndriessenKian D. LiemPieter L.J. DegraeuweSiska CroubelsJoske Millecam et al.

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Evaluation of the efficacy of mycotoxin modifiers and mycotoxin binders by using an in vitro rumen model as a first screening tool

Sandra DebevereDian SchatzmayrNicole ReisingerMarkus AleschkoGeert HaesaertMichael RychlikSiska CroubelsVeerle Fievez

A1 Journal Article in TOXINS

Gastrostomy tube placement via a laparotomic procedure in growing conventional piglets to perform multi-dose preclinical paediatric drug studies

Joske MillecamThomas van BergenMathias DevreeseStijn SchauvliegeAnn MartensKoen ChiersSiska CroubelsGunther Antonissen

A1 Journal Article in LABORATORY ANIMALS

Grasping the phenomenon of augmented renal clearance in the critically ill using the conventional pig as juvenile animal model

Laura DhondtMathias DevreeseSiska CroubelsPeter De PaepePieter De Cock

Highly sensitive multi-residue analysis of veterinary drugs including coccidiostats and anthelmintics in pond water using UHPLC-MS/MS : application to freshwater ponds in Flanders, Belgium

Tess GoessensSiegrid De BaereNiels De TroyerArne DeknockPeter GoethalsLuc LensFrank PasmansSiska Croubels

A1 Journal Article in ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS

In vitro rumen simulations show a reduced disappearance of deoxynivalenol, nivalenol and enniatin B at conditions of rumen acidosis and lower microbial activity

Sandra DebevereAn CoolsSiegrid De BaereGeert HaesaertMichael RychlikSiska CroubelsVeerle Fievez

A1 Journal Article in TOXINS

Interactions between mycotoxins and the rumen and their possible toxicological effects on the gastrointestinal tract of dairy cattle : an in vitro approach

Sandra DebevereSiska CroubelsVeerle Fievez

Investigation of age-related differences in toxicokinetic processes of deoxynivalenol and deoxynivalenol-3-glucoside in weaned piglets

Amelie CatteuwMathias DevreeseSiegrid De BaereGunther AntonissenLada IvanovaSilvio UhligAnn MartensSarah De SaegerMarthe De BoevreSiska Croubels

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Multi-class analysis of 46 antimicrobial drug residues in pond water using UHPLC-Orbitrap-HRMS and application to freshwater ponds in Flanders, Belgium

Tess GoessensSteve HuysmanNiels De TroyerArne DeknockPeter GoethalsLuc LensLynn VanhaeckeSiska Croubels

A1 Journal Article in TALANTA

Multi-mycotoxin occurrence in dairy cattle and poultry feeds and feed ingredients from Machakos Town, Kenya

David KemboiPhillis Emelda OchiengGunther AntonissenSiska CroubelsMarie-Louise ScippoSheila OkothErastus K. KangetheJohannes FaasBarbara DoupovecJohanna F. Lindahl et al.

A1 Journal Article in TOXINS

Pediatric pharmacology of desmopressin in children with enuresis : a comprehensive review

Elke GasthuysLien DosscheRobin MicheletJens Peter NorgaardMathias DevreeseSiska CroubelsAn VermeulenJan Van BocxlaerJohan Vande Walle

A1 Journal Article in PEDIATRIC DRUGS

Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs

Lise VlerickMathias DevreeseKathelijne PeremansRobrecht DockxSiska CroubelsLuc DuchateauIngeborgh Polis

A1 Journal Article in PLOS ONE

Presence of low virulence chytrid fungi could protect European amphibians from more deadly strains

Mark GreenerElin VerbruggheMoira KellyMark BlooiWouter BeukemaStefano CanessaSalvador CarranzaSiska CroubelsNiels De TroyerDaniel Fernandez-Giberteau et al.

A1 Journal Article in NATURE COMMUNICATIONS

Simultaneous measurement of glomerular filtration rate, effective renal plasma flow and tubular secretion in different poultry species by single intravenous bolus of iohexol and para-aminohippuric acid

Lenka StroobantSiska CroubelsLaura DhondtJoske MillecamSiegrid De BaereElke GasthuysJ MorrensGunther Antonissen

A1 Journal Article in ANIMALS

Stability, homogeneity and carry-over of amoxicillin, doxycycline, florfenicol and flubendazole in medicated feed and drinking water on 24 pig farms

Femke VandaelHelena Cardoso de Carvalho FerreiraMathias DevreeseJeroen DewulfEls DaeseleireMia EeckhoutSiska Croubels

A1 Journal Article in ANTIBIOTICS-BASEL

The impact of therapeutic-dose induced intestinal enrofloxacin concentrations in healthy pigs on fecal Escherichia coli populations

Joren De SmetFilip BoyenSiska CroubelsGeertrui RasschaertFreddy HaesebrouckRobin TemmermanSofie RutjensPatrick De BackerMathias Devreese

A1 Journal Article in BMC VETERINARY RESEARCH

The incidence of citrinin in the Belgian food and feed chain and the risk for human and animal health

Celine MeerpoelSarah De SaegerSiska CroubelsMathias Devreese

The lidocaine/monoethylglycylxylidide liver function test to assess shunt closure in dogs with attenuated congenital extrahepatic portosystemic shunts

Nausikaa DevriendtGonçalo SerranoSiska CroubelsDominique PaepeRafael NickelHilde De Rooster

The role of alanine glyoxylate transaminase-2 (agxt2) in β-alanine and carnosine metabolism of healthy mice and humans

Jan StautemasNatalia JarzebskaZhou Xiang ShanLaura BlancquaertInge EveraertSarah de JagerSiegrid De BaereArne HautekietAnneke VolkaertFilip Lefevere et al.

A1 Journal Article in EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Towards a food web based control strategy to mitigate an amphibian panzootic in agricultural landscapes

Arne DeknockPeter GoethalsSiska CroubelsLuc LensAn MartelFrank Pasmans

A1 Journal Article in GLOBAL ECOLOGY AND CONSERVATION

Toxicokinetic studies in piglets reveal age-related differences in systemic exposure to zearalenone, zearalenone-14-glucoside, and zearalenone-14-sulfate

Amelie CatteuwMathias DevreeseSiegrid De BaereGunther AntonissenBart HuybrechtsLada IvanovaSilvio UhligAnn MartensSarah De SaegerMarthe De Boevre et al.

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Toxicokinetics of hydrolyzed fumonisin B1 after single oral or intravenous bolus to broiler chickens fed a control or a fumonisins-contaminated diet

Gunther AntonissenSiegrid De BaereBarbara NovakDian SchatzmayrDanica den HollanderMathias DevreeseSiska Croubels

A1 Journal Article in TOXINS

Weight-gain induced changes in renal perfusion assessed by contrast-enhanced ultrasound precede increases in urinary protein excretion suggestive of glomerular and tubular injury and normalize after weight-loss in dogs

Daisy LiuEmmelie StockBart BroeckxSylvie DaminetEvelyne MeyerJoris DelangheSiska CroubelsMathias DevreesePatrick NguyenEvelien Bogaerts et al.

A1 Journal Article in PLOS ONE

2019

A phytogenic feed additive suppresses inflammatory signals in the gut by controlling the activation of the MAPK pathway and decreasing the level of Enterobacteriaceae in broiler chickens

Gunther AntonissenFilip Van ImmerseelVasileios ParaskeuasEirini GrielaMarc VerlindenRichard DucatelleFreddy HaesebrouckNicole ReisingerSiska CroubelsKostas Mountzouris

Accuracy of renal function estimating equations compared to iohexol clearance in critically ill children

Evelyn DhontCharlotte WindelsTatjana Van Der HeggenANNIK DE JAEGERJef WillemsSiska CroubelsSiegrid De BaereJohan Vande WallePeter De PaepePieter De Cock

Age-related differences in exposure to deoxynivalenol and deoxynivalenol-3-glucoside unravelled : toxicokinetic study in the weaned piglet as a human paediatric surrogate model

Amelie CatteuwGunther AntonissenLada IvanovaSilvio UhligAnn MartensSarah De SaegerMarthe De BoevreMathias DevreeseSiska Croubels

Agricultural contaminants in the aquatic environment in Flanders : current situation

Tess GoessensSiska CroubelsPeter GoethalsFrank PasmansLuc LensLynn VanhaeckePieter Spanoghe

Alfaxalone total intravenous anaesthesia in dogs : pharmacokinetics, cardiovascular data and recovery characteristics

Virginie DehuisserTim BosmansMathias DevreeseRonette GehringSiska CroubelsLuc DuchateauIngeborgh Polis

A1 Journal Article in VETERINARY ANAESTHESIA AND ANALGESIA

Assessment of dried blood spots for multi-mycotoxin biomarker analysis in pigs and broiler chickens

Marianne LauwersSiska CroubelsSiegrid De BaereMilena SevastiyanovaEva Maria Romera SierraBen LetorChristos GougouliasMathias Devreese

A1 Journal Article in TOXINS

Biomarkers for exposure as a tool for efficacy testing of a mycotoxin detoxifier in broiler chickens and pigs

Marianne LauwersSiska CroubelsBen LetorChristos GougouliasMathias Devreese

A1 Journal Article in TOXINS

Biomarkers for mycotoxin exposure in livestock

Marianne LauwersMathias DevreeseSiska CroubelsBen LetorChristos Gougoulias

Breast levonorgestrel concentrations in women using a levonorgestrel-releasing intrauterine system

Herman DepypereFrank Z StanczykSiska CroubelsPhillip BlondeelNathalie RocheBernard DepypereLynn Vanhaecke

A1 Journal Article in CONTRACEPTION

Cardiovascular, respiratory, gastrointestinal and behavioral effects of intravenous lidocaine in healthy, conscious horses and evaluation of the relationship with lidocaine and monoethylglycinexylidide serum concentrations

A SalcicciaDM Lopez ArevaloAn MaesSiska CroubelsV BusoniJ DetilleuxC SandersenH Amory

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective

Wim SchelstraeteLaura De ClerckElisabeth GovaertJoske MillecamMathias DevreeseDieter DeforceJan Van BocxlaerSiska Croubels

A1 Journal Article in SCIENTIFIC REPORTS

Citrinin : new occurrence, toxicokinetic and toxicity data to refine its risk assessment

Celine MeerpoelArnau Vidal CorominasBart HuybrechtsEmmanuel TangniSarah De SaegerSiska CroubelsMathias Devreese

Comparative physiology of glomerular filtration rate by plasma clearance of exogenous creatinine and exo-iohexol in six different avian species

Elke GasthuysAndrés MontesinosNele CaekebekeMathias DevreeseSiegrid De BaereMaria ArdiacaDominique PaepeSiska CroubelsGunther Antonissen

A1 Journal Article in SCIENTIFIC REPORTS

Comparison of renal function estimation methods in critically ill children : a pilot study

Evelyn DhontTatjana Van Der HeggenANNIK DE JAEGERJef WillemsSiska CroubelsSiegrid De BaereJohan Vande WallePeter De PaepePieter De Cock

Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of iohexol, p-aminohippuric acid and creatinine in porcine and broiler chicken plasma

Laura DhondtSiska CroubelsPieter De CockPeter De PaepeSiegrid De BaereMathias Devreese

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Development of an UPLC-MS/MS method for the analysis of mycotoxins in rumen fluid with and without maize silage emphasizes the importance of using matrix-matched calibration

Sandra DebevereSiegrid De BaereGeert HaesaertMichael RychlikVeerle FievezSiska Croubels

A1 Journal Article in TOXINS

Developmental pharmacokinetics and safety of ibuprofen and its enantiomers in the conventional pig as potential pediatric animal model

Joske MillecamThomas van BergenStijn SchauvliegeGunther AntonissenAnn MartensKoen ChiersRonette GehringElke GasthuysJohan Vande WalleSiska Croubels et al.

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Diet-Induced dysbiosis of the intestinal microbiota in broiler chickens

Gunther AntonissenEvy GoossensVasilis ParaskeuasEirini GrielaMarc VerlindenSiska CroubelsRichard DucatelleFreddy HaesebrouckNicole ReisingerFilip Van Immerseel et al.

Dynamic screening of agricultural contaminants in freshwater ecosystems as part of amphibian biodiversity conservation

Tess GoessensLynn VanhaeckePieter SpanogheLuc LensPeter GoethalsAn MartelFrank PasmansSiska Croubels

Environmental screening of agricultural contaminants in fresh water ecosystems as part of amphibian biodiversity conservation

Tess GoessensM. HoubrakenJasmine De RopPeter GoethalsFrank PasmansPieter SpanogheSiska Croubels

Impact of subacute exposure to T-2 toxin and zearalenone on the pharmacokinetics of midazolam as CYP3A probe drug in a porcine animal model : a pilot study

Wim SchelstraeteMathias DevreeseSiska Croubels

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

In vitro rumen simulations show a lower disappearance of deoxynivalenol, nivalenol, zearalenone and enniatin B at conditions of rumen acidosis and at dry conditions

Sandra DebevereSiegrid De BaereGeert HaesaertMichael RychlikSiska CroubelsVeerle Fievez

In vivo metabolism of ibuprofen in growing conventional pigs : a pharmacokinetic approach

Joske MillecamSiegrid De BaereSiska CroubelsMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Influence of administration route and dose on intestinal concentrations of selected antimicrobials in pigs

Joren De SmetMathias DevreeseSiska Croubels

Insights into in vivo absolute oral bioavailability, biotransformation, and toxicokinetics of zearalenone, α-zearalenol, β-zearalenol, zearalenone-14-glucoside, and zearalenone-14-sulfate in pigs

Amelie CatteuwNathan BroekaertSiegrid De BaereMarianne LauwersElke GasthuysBart HuybrechtsAlfons CallebautLada IvanovaSilvio UhligMarthe De Boevre et al.

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Interactions between Fusarium mycotoxins and cytochrome P450 drug metabolizing enzymes in a porcine animal model

Wim SchelstraeteSiska CroubelsMathias Devreese

Lower in vitro rumen metabolization of mycotoxins at conditions of rumen acidosis and dry conditions

Sandra DebevereSiegrid De BaereGeert HaesaertSiska CroubelsVeerle Fievez

Multi LC-MS/MS and LC-HRMS methods for determination of 24 mycotoxins including major phase I and II biomarker metabolites in biological matrices from pigs and broiler chickens

Marianne LauwersSiegrid De BaereBen LetorMichael RychlikSiska CroubelsMathias Devreese

A1 Journal Article in TOXINS

Multi-class screening of antimicrobial drug residues with high resolution mass spectrometry

Tess GoessensSteve HuysmanPeter GoethalsAnn DumoulinLynn VanhaeckeSiska Croubels

Mycotoxins in Flanders’ Fields : occurrence and correlations with fusarium species in whole-plant harvested maize

Jonas VandickeKatrien De VisschereSiska CroubelsSarah De SaegerKris AudenaertGeert Haesaert

A1 Journal Article in MICROORGANISMS

Occurrence, oral bioavailability and toxicokinetics of citrinin in a porcine animal model

Celine MeerpoelArnau Vidal CorominasBart HuybrechtsEmmanuel TangniSarah De SaegerMathias DevreeseSiska Croubels

Occurrence, toxicokinetics and toxicity of citrinin and risk assessment

Celine MeerpoelArnau Vidal CorominasBart HuybrechtsEmmanuel TangniSarah De SaegerSiska CroubelsMathias Devreese

Oral group medication in pig production : characterising medicated feed and drinking water systems

Femke VandaelMaria Eleni FilippitziJeroen DewulfEls DaeseleireMia EeckhoutMathias DevreeseSiska Croubels

A1 Journal Article in VETERINARY RECORD

Pharmacokinetics and absolute oral bioavailability of meloxicam in guinea pigs (Cavia porcellus)

Ilse MoeremansMathias DevreeseSiegrid De BaereSiska CroubelsKatleen Hermans

A1 Journal Article in VETERINARY ANAESTHESIA AND ANALGESIA

Pharmacokinetics and muscle residue depletion of amoxicillin in cage cultured hybrid red tilapia (Oreochromis mossambicus × Oreochromis niloticus)

Tran Minh PhuNguyen Tam EmNguyen Quoc ThinhNguyen Thanh PhươngAnders DalgaardMarie-Louise ScippoMathias DevreeseSiska Croubels

A1 Journal Article in AQUACULTURE

Piglets as animal model to assess the contribution of fluid therapy to the development of augmented renal clearance in children

Laura DhondtSiska CroubelsPeter De PaepePieter De CockMathias Devreese

The conventional pig as juvenile animal model for preclinical paediatric pharmacokinetic studies : focus on hepatic metabolism using ibuprofen as model compound

Joske MillecamSiska CroubelsMathias Devreese

The juvenile pig as animal model for unraveling renal drug elimination processes in children

Laura DhondtSiska CroubelsPeter De PaepePieter De CockMathias Devreese

The role of roughage provision on the absorption and disposition of the mycotoxin deoxynivalenol and its acetylated derivatives in calves : from field observations to toxicokinetics

Bonnie ValgaerenLéonard ThéronSiska CroubelsMathias DevreeseSiegrid De BaereEls Van PamelEls DaeseleireMarthe De BoevreSarah De SaegerArnau Vidal Corominas et al.

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Towards risk assessment of emerging Alternaria and Fusarium mycotoxins : comparative toxicity and toxicokinetics in broiler chickens and pigs

Sophie FraeymanSiska CroubelsMathias DevreeseGunther Antonissen

Ultra-high-performance liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry for multi-residue screening of pesticides, (veterinary) drugs and mycotoxins in edible insects

Ellen De PaepeJella WautersMik Van Der BorghtJohan ClaesSteve HuysmanSiska CroubelsLynn Vanhaecke

A1 Journal Article in FOOD CHEMISTRY

Validated multi-mycotoxin analysis using dried blood spots for pigs and broiler chickens applied in a screening and toxicokinetic study

Marianne LauwersSiska CroubelsBen LetorMathias Devreese

2018

A novel approach in paediatric drug research : the development of a juvenile pig model for pharmacokinetic/pharmacodynamic studies, using desmopressin as case 1

Elke GasthuysJoske MillecamMathias DevreeseAn VermeulenPauline De BruyneJohan Vande WalleJoris DelangheSiska Croubels

A survey of citrinin and ochratoxin A in food and feed in Belgium

Celine MeerpoelArnau Vidal CorominasYasemin BasB HuybrechtsE TangniMathias DevreeseSiska CroubelsSarah De Saeger

Analysis of the Chemical Safety of Insect Consumption as Alternative for the Increasing Food Requirements

Ellen De PaepeJella WautersSiska CroubelsMik Van Der BorghtJohan ClaesLynn Vanhaecke

Carry-over of tetracyclines and sulphonamides-trimethoprim in pig feed : resistance selection in the pig microbiota caused by doxycycline

Laura PeetersSiska CroubelsPatrick ButayeGeertrui RasschaertAnnemieke Smet

Changes in renal perfusion precede increased urinary protein excretion caused by weight gain and normalize after weight-loss in dogs

Daisy LiuEmmelie StockEvelien BogaertsBart BroeckxSiska CroubelsMathias DevreeseSylvie DaminetPatrick NguyenMyriam HestaKatrien Vanderperren

Chronic dietary intake of enniatin B in broiler chickens has low impact on intestinal morphometry and hepatic histology, and shows limited transfer to liver tissue

Sophie FraeymanSiska CroubelsMathias DevreeseRichard DucatelleMichael RychlikGunther Antonissen

A1 Journal Article in TOXINS

Clinical impact of deoxynivalenol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on the severity of an experimental Mycoplasma hyopneumoniae infection in pigs

Annelies MichielsIoannis ArsenakisAnneleen MatthijsFilip BoyenGeert HaesaertKris AudenaertMia EeckhoutSiska CroubelsFreddy HaesebrouckDominiek Maes

A1 Journal Article in BMC VETERINARY RESEARCH

Comparative in vitro cytotoxicity of the emerging Fusarium mycotoxins beauvericin and enniatins to porcine intestinal epithelial cells

Sophie FraeymanEvelyne MeyerMathias DevreeseGunther AntonissenKristel DemeyereFreddy HaesebrouckSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Comparative toxicokinetics and plasma protein binding of ochratoxin A in four avian species

Mathias DevreeseSiska CroubelsSiegrid De BaereRonette GehringGunther Antonissen

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research : postnatal maturation of the glomerular filtration rate

Elke GasthuysJoske MillecamMathias DevreeseJoris DelangheJohan Vande WalleMarjolein HeyndrickxSiska Croubels

Development and validation of a UPLC-MS/MS and UPLC-HR-MS method for the determination of fumonisin B1 and its hydrolysed metabolites and fumonisin B2 in broiler chicken plasma

Siegrid De BaereSiska CroubelsBarbara NovakGerlinde BichlGunther Antonissen

A1 Journal Article in TOXINS

Development and validation of an LC-MS/MS method for the simultaneous determination of citrinin and ochratoxin a in a variety of feed and foodstuffs

Celine MeerpoelArnau Vidal CorominasJosé Diana Di MavunguBart HuybrechtsEmmanuel K TangniMathias DevreeseSiska CroubelsSarah De Saeger

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Effect of residual doxycycline concentrations on resistance selection and transfer in porcine commensal Escherichia coli

Laura PeetersSiska CroubelsGeertrui RasschaertHein ImberechtsEls DaeseleireJeroen DewulfMarc HeyndrickxPatrick ButayeFreddy HaesebrouckAnnemieke Smet

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Elevated urinary excretion of free pyridinoline in Friesian horses suggests a breed-specific increase in collagen degradation

Veronique SaeyJonathan TangRichard DucatelleSiska CroubelsSiegrid De BaereStijn SchauvliegeGunther van LoonKoen Chiers

A1 Journal Article in BMC VETERINARY RESEARCH

Environmental screening of multi-class antimicrobial drug residues in salt and fresh water ecosystems using targeted and untargeted high resolution mass spectrometry

Tess GoessensSteve HuysmanPeter GoethalsAnn DumoulinLynn VanhaeckeSiska Croubels

Fluoroquinolone resistance in clinical avian pathogenic Escherichia coli (APEC) isolates from Flanders: Is the poultry industry at risk?

Robin TemmermanAn GarmynGunther AntonissenGerty VanantwerpenMia VanrobaeysSiska CroubelsMathias Devreese

Impact of T-2 toxin and zearalenone on the pharmacokinetics of midazolam as CYP3A probe drug in an in vivo porcine animal model

Wim SchelstraeteMathias DevreeseSiska Croubels

In vitro model to assess the adsorption of oral veterinary drugs to mycotoxin binders in a feed- and aflatoxin B1-containing buffered matrix

Siegrid De BaereThomas De MilGunther AntonissenMathias DevreeseSiska Croubels

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

In vitro rumen simulation shows detoxification of the mycotoxin deoxynivalenol and activation of the mycotoxin zearalenone, but also adhesion of mycotoxins to maize silage

Sandra DebevereSiegrid De BaereGeert HaesaertMichael RychlikVeerle FievezSiska Croubels

Incidence of citrinin in the Belgian feed chain and its toxicokinetic profile in broiler chickens

Celine MeerpoelArnau Vidal CorominasB HuybrechtsE TangniSarah De SaegerMathias DevreeseSiska Croubels

Intratumoral chemotherapy in an integumentary squamous cell carcinoma in a cockatiel (Nymphicus hollandicus)

Naomi Van HeckeAn MartelAn GarmynIsabel Van de MaeleTom HellebuyckSiska CroubelsRichard DucatelleGunther Antonissen

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : fact or fiction?

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Maturation of hepatic cytochrome P450 enzymes in conventional pigs : the added value of proteomics

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Maturation of hepatic cytochrome P450 enzymes in conventional pigs as model for preclinical paediatric drug research

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

Pediatric drug development: towards maturity : desmopressin as a case

Elke GasthuysRobin MicheletLien DosschePauline De BruyneJohan Vande WalleAn VermeulenMathias DevreeseSiska Croubels

Pharmacokinetics and electrophysiological effects of sotalol hydrochloride in horses

Barbara BrouxDominique De ClercqAnnelies DecloedtLisse VeraMathias DevreeseR GehringSiska CroubelsGunther van Loon

A1 Journal Article in EQUINE VETERINARY JOURNAL

Pharmacokinetics of florfenicol in turkey plasma, lung tissue, and pulmonary epithelial lining fluid after single oral bolus or continuous administration in the drinking water

Anneleen WatteynSiska CroubelsSiegrid De BaerePatrick De BackerMathias Devreese

A1 Journal Article in POULTRY SCIENCE

Pharmacokinetics of ibuprofen in very preterm infants with patent ductus arteriosus

Aline EngbersRobert FlintSwantje VöllerJohan de KlerkIrwin ReissPeter AndriessenDjien LiemPieter DegraeuweSiska CroubelsJoske Millecam et al.

PK/PD studies in pigs leading to optimization of treatment dose in MNE?

Elke GasthuysLien DosscheSiska CroubelsPauline De BruyneMathias DevreeseAn VermeulenJohan Vande Walle

Population pharmacokinetic modeling of a desmopressin oral lyophilisate in growing piglets as a model for the pediatric population

Elke GasthuysAn VermeulenSiska CroubelsJoske MillecamStijn SchauvliegeThomas van BergenPauline De BruyneJohan Vande WalleMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Population pharmacokinetic modeling of a desmopressin oral lyophilisate in growing piglets as a model for the pediatric population

Elke GasthuysAn VermeulenSiska CroubelsPauline De BruyneJoske MillecamJohan Vande WalleMathias Devreese

Prevention of mycotoxicosis using mycotoxin detoxifiers : in vivo efficacy testing of a mycotoxin detoxifier in broilers : toxicokinetic approach

Amelie CatteuwBeatrice WeggeJanez BartoloSiska CroubelsMathias Devreese

Similar gastro-intestinal exposure to florfenicol after oral or intramuscular administration in pigs, leading to resistance selection in commensal Escherichia coli

Joren De SmetFilip BoyenSiska CroubelsGeertrui RasschaertFreddy HaesebrouckPatrick De BackerMathias Devreese

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Simultaneous determination of creatinine, iohexol and p-aminohippuric acid in animal plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry

Laura DhondtSiska CroubelsPieter De CockPeter De PaepeMathias Devreese

Storage stability study of porcine hepatic and intestinal cytochrome P450 isoenzymes by use of a newly developed and fully validated highly sensitive HPLC-MS/MS method

Wim SchelstraeteMathias DevreeseSiska Croubels

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Targeted and untargeted screening of multi-class antimicrobial drug residues with high resolution mass spectrometry in salt and fresh water ecosystems

Tess GoessensSteve HuysmanPeter GoethalsAnn DumoulinLynn VanhaeckeSiska Croubels

The composition of drinking water and feeding systems for oral group medication in 52 Belgian swine herds, in relation to homogeneity, stability and cross-contamination of veterinary medicinal products

Femke VandaelJeroen DewulfE DaeseleireMia EeckhoutPatrick De BackerMathias DevreeseSiska Croubels

The development of a juvenile porcine augmented renal clearance model for paediatric drug research during sepsis : the effect of different continuously administered LPS doses on the renal function

Laura DhondtSiska CroubelsPieter De CockPeter De PaepeMathias Devreese

The ontogeny of cytochrome P450 enzyme activity and protein abundance in conventional pigs in support of preclinical pediatric drug research

Joske MillecamLaura De ClerckElisabeth GovaertMathias DevreeseElke GasthuysWim SchelstraeteDieter DeforceLies De BockJan Van BocxlaerStanislas Sys et al.

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

2017

A new approach in pediatric drug design : the development of a pediatric pig model, part II : the maturation of hepatic cytochrome P450 enzymes using enzyme activity and proteomics

Joske MillecamElke GasthuysMathias DevreeseDieter DeforceLies De BockJan Van BocxlaerSiska Croubels

A novel approach in paediatric drug design : the conventional pig as juvenile animal model

Joske MillecamElke GasthuysMathias DevreeseSiska Croubels

A novel approach in paediatric drug research : the development of a juvenile conventional pig model for pharmacokinetic/pharmacodynamic studies, using desmopressin as case

Elke GasthuysSiska CroubelsMathias Devreese

A survey of citrinin and ochratoxin A in food and feed on the Belgian market

Celine MeerpoelJosé Diana Di MavunguB HuybrechtsE TangniMathias DevreeseSiska CroubelsSarah De Saeger

Absorption and disposition of enniatin B1 in broiler chickens and pigs : comparative oral bioavailability and toxicokinetics

Sophie FraeymanMathias DevreeseGunther AntonissenSiegrid De BaereMichael RychlikLada IvanovaChristiane FaesteSiska Croubels

Behavior of mycotoxins in maize silage in in vitro rumen simulations

Sandra DebevereSiegrid De BaereGeert HaesaertMichael RychlikVeerle FievezSiska Croubels

Biotransformation of the mycotoxin enniatin B1 in pigs : a comparative in vitro and in vivo approach

Lada IvanovaSilvio UhligMathias DevreeseSiska CroubelsChristiane Kruse Fæste

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Citririsk : incidence of citrinin in the Belgian food and feed chain & risk for human and animal health

Celine MeerpoelJosé Diana Di MavunguB HuybrechtsE TangniMathias DevreeseSiska CroubelsSarah De Saeger

Comparative population pharmacokinetics and absolute oral bioavailability of COX-2 selective inhibitors celecoxib, mavacoxib and meloxicam in cockatiels (Nymphicus hollandicus)

Laura DhondtMathias DevreeseSiska CroubelsSiegrid De BaereRoel HaesendonckTess GoessensRonette GehringPatrick De BackerGunther Antonissen

A1 Journal Article in SCIENTIFIC REPORTS

Comparative toxicokinetics of enniatins in broiler chickens and pigs

Sophie FraeymanMathias DevreeseGunther AntonissenSiegrid De BaereMichael RychlikLada IvanovaSiska Croubels

Development and validation of an UPLC-MS/MS multi-method for the quantitative analysis of important mycotoxins in rumen fluid

Sandra DebevereSiegrid De BaereGeert HaesaertMichael RychlikVeerle FievezSiska Croubels

Effect of administration route and dose alteration on sulfadiazine-trimethoprim plasma and intestinal concentrations in pigs

Joren De SmetSiska CroubelsPatrick De BackerMathias Devreese

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Effect of weight gain in dogs on renal function and perfusion assessed by contrast-enhanced ultrasound

Daisy LiuMyriam HestaEmmelie StockSiska CroubelsMathias DevreeseBart BroeckxEvelien BogaertsSylvie DaminetKatrien Vanderperren

Emerging Fusarium and Alternaria mycotoxins : occurrence, toxicity and toxicokinetics

Sophie FraeymanSiska CroubelsMathias DevreeseGunther Antonissen

A1 Journal Article in TOXINS

Feed contamination with Fusarium mycotoxins induces a corticosterone stress response in broiler chickens

Gunther AntonissenSiegrid De BaereMathias DevreeseFilip Van ImmerseelAn MartelSiska Croubels

A1 Journal Article in POULTRY SCIENCE

Florfenicol concentrations in different gastro-intestinal segments of pigs, after oral and intramuscular treatments

Joren De SmetSiska CroubelsPatrick De BackerMathias Devreese

Het gebruik van psychofarmaca bij verenplukkende papegaaien

Jinne GortemanGunther AntonissenSiska CroubelsYvonne van Zeeland

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Impact of Fusarium mycotoxins on hepatic and intestinal mRNA expression of cytochrome P450 enzymes and drug transporters, and on the pharmacokinetics of oral enrofloxacin in broiler chickens

Gunther AntonissenMathias DevreeseSiegrid De BaereAn MartelFilip Van ImmerseelSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Impact of Fusarium mycotoxins on in vitro activity of major hepatic cytochrome P450 biotransformation enzymes in pigs

Wim SchelstraeteMathias DevreeseSiska Croubels

In vivo contribution of deoxynivalenol-3-β-D-glucoside to deoxynivalenol exposure in broiler chickens and pigs: oral bioavailability, hydrolysis and toxicokinetics

Nathan BroekaertMathias DevreeseThomas van BergenStijn SchauvliegeMarthe De BoevreSarah De SaegerLynn VanhaeckeFranz BerthillerHerbert MichlmayrAlexandra Malachová et al.

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Influence of mycotoxin binders on the oral bioavailability of tylosin, doxycycline, diclazuril, and salinomycin in fed broiler chickens

Thomas De MilMathias DevreeseAn MaesSarah De SaegerPatrick De BackerSiska Croubels

A1 Journal Article in POULTRY SCIENCE

Pathofysiologie van lipopolysaccharide geïnduceerde inflammatoire respons bij vogels

Renée HoubenSiska CroubelsAnneleen WatteynGunther Antonissen

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Pharmacokinetic and urinary profiling reveals the prednisolone/cortisol ratio as a valid biomarker for prednisolone administration

Lieven Van MeulebroekNathalie De ClercqJulie Vanden BusscheMathias DevreeseEric FichantPhilippe DelahautSiska CroubelsLynn Vanhaecke

A1 Journal Article in BMC VETERINARY RESEARCH

Population pharmacokinetic modeling of the glomerular filtration rate in growing piglets using iohexol

Elke GasthuysJoske MillecamSiska CroubelsRonette GehringMathias Devreese

Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research

Elke GasthuysMathias DevreeseJoske MillecamStanislas SysKatrien VanderperrenJoris DelangheJohan Vande WalleMarjolein HeyndrickxSiska Croubels

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

Repetitive urine and blood sampling in neonatal and weaned piglets for pharmacokinetic and pharmacodynamic modelling in drug discovery : a pilot study

Elke GasthuysStijn SchauvliegeThomas van BergenJoske MillecamIlaria CerasoliAnn MartensFrank GasthuysTim VandecasteelePieter CornillieWim Van Den Broeck et al.

A1 Journal Article in LABORATORY ANIMALS

Role of mycotoxins in herds with and without problems with tail necrosis in neonatal pigs

Tommy Van LimbergenMathias DevreeseSiska CroubelsNathan BroekaertAnnelies MichielsSarah De SaegerDominiek Maes

A1 Journal Article in VETERINARY RECORD

Selection and transfer of an IncI1-tet(A) plasmid of Escherichia coli in an ex vivo model of the porcine caecum at doxycycline concentrations caused by cross-contaminated feed

Laura PeetersT De MulderE Van CoillieJ HuygensA SmetE DaeseleireJeroen DewulfH ImberechtsPatrick ButayeFreddy Haesebrouck et al.

A1 Journal Article in JOURNAL OF APPLIED MICROBIOLOGY

T-2 toxin-3α-glucoside in broiler chickens : toxicokinetics, absolute oral bioavailability, and in vivo hydrolysis

Nathan BroekaertMathias DevreeseMarthe De BoevreSarah De SaegerSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The conventional pig as PK/PD/toxicity model for the pediatric subpopulation : development of urine and blood sampling strategies in growing piglets

Elke GasthuysThomas van BergenStijn SchauvliegeJoske MillecamSiska CroubelsMathias Devreese

The ontogeny of hepatic cytochrome P450 enzymes in conventional pigs using enzyme activity and proteomics

Joske MillecamElke GasthuysMathias DevreeseDieter DeforceJan Van BocxlaerSiska Croubels

The use of population pharmacokinetics for pharmacokinetic studies in small and exotic avian species : the case of celecoxib, mavacoxib and meloxicam in cockatiels (Nymphicus hollandicus)

Laura DhondtMathias DevreeseSiska CroubelsSiegrid De BaereRoel HaesendonckTess GoessensRonette GehringPatrick De BackerGunther Antonissen

The use of toxicokinetic modeling in mycotoxin research

Amelie CatteuwMarianne LauwersNathan BroekaertGunther AntonissenMathias DevreeseSiska Croubels

Ultra-high performance liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry for multi-residue screening of pesticides, (veterinary) drugs and mycotoxins in insects

Jella WautersEllen De PaepeEline KowalskiSiska CroubelsJohan ClaesLynn Vanhaecke

Validated LC-MS/MS multi-methods to detect 25 mycotoxins and phase I metabolites in biological fluids of pigs and broiler chickens and application to screening studies for mycotoxin exposure

Marianne LauwersSiegrid De BaereTommy Van LimbergenGunther AntonissenBen LetorDominiek MaesMathias DevreeseSiska Croubels

Veterinary drug residues in foods

Els DaeseleireEls Van PamelChristof Van PouckeSiska Croubels

Bookchapter in Chemical contaminants and residues in food

2016

Biomarkers for exposure of mycotoxins in pigs and broiler chickens

Marianne LauwersSiegrid De BaereBen LetorSarah De SaegerSiska CroubelsMathias Devreese

Caffeine prevents hyperoxia-induced functional and structural lung damage in preterm rabbits

Taro NagatomoJulio JiménezJute RichterSiegrid De BaereJeroen VanoirbeekGunnar NaulaersKarel AllegaertSiska CroubelsJan DeprestJaan Toelen

A1 Journal Article in NEONATOLOGY

Comparative in vitro cytotoxicity of modified deoxynivalenol on porcine intestinal epithelial cells

Nathan BroekaertMathias DevreeseKristel DemeyereFranz BerthillerHerbert MichlmayrElisabeth VargaGerhard AdamEvelyne MeyerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Comparative oral bioavailability, toxicokinetics, and biotransformation of enniatin B1 and enniatin B in broiler chickens

Sophie FraeymanMathias DevreeseGunther AntonissenSiegrid De BaereMichael RychlikSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Deoxynivalenol-3-β-D-glucoside : in vitro cytotoxicity and in vivo oral bioavailability and hydrolysis in broiler chicken and pig

Nathan BroekaertMathias DevreeseThomas van BergenStijn SchauvliegeMarthe De BoevreSarah De SaegerLynn VanhaeckeFranz BerthillerHerbert MichlmayrAlexandra Malachova et al.

Disposition of enniatin B and B1 in broiler chickens : oral bioavailability and toxicokinetics

Sophie FraeymanMathias DevreeseGunther AntonissenSiegrid De BaereMichael RychlikSiska Croubels

Efficacy of florfenicol and gamithromycin in an Ornithobacterium rhinotracheale infection model in turkeys : a pharmacokinetic/pharmacodynamic integration

Anneleen WatteynSiska CroubelsPatrick De BackerMathias Devreese

Efficacy of gamithromycin against Ornithobacterium rhinotracheale in turkey poults pre-infected with avian metapneumovirus

Anneleen WatteynMathias DevreeseElke PlessersHeidi WynsAn GarmynVishwanatha Reddy Avalakuppa Papi ReddyFrank PasmansAn MartelFreddy HaesebrouckPatrick De Backer et al.

A1 Journal Article in AVIAN PATHOLOGY

Evaluation of cystatin C for the detection of chronic kidney disease in cats

Liesbeth GhysDominique PaepeH LefebvreB ReynoldsSiska CroubelsEvelyne MeyerJoris DelangheSylvie Daminet

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

Farmacokinetiek van geneesmiddelen bij vogels en de toepassingen en beperkingen van dosisextrapolatie

Renée HoubenGunther AntonissenSiska CroubelsPatrick De BackerMathias Devreese

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

GLP principles and their role in supporting pharmacokinetic and residue depletion studies for drug registration and licensing

Siska CroubelsPatrick De BackerMathias Devreese

A1 Journal Article in DRUG TESTING AND ANALYSIS

Immunomodulatory properties of gamithromycin and ketoprofen in lipopolysaccharide-challenged calves with emphasis on the acute-phase response

Elke PlessersHeidi WynsAnneleen WatteynBart PardonSiegrid De BaereStanislas SysPatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Influence of mycotoxin binders on the oral bioavailability of doxycycline in pigs

Thomas De MilMathias DevreeseSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Influence of mycotoxin binders on the oral bioavailability of doxycycline in pigs

Thomas De MilMathias DevreeseSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

Interaction between Fusarium mycotoxins and cytochrome P450 drug metabolizing enzymes/ABC drug transporters in a porcine animal model

Wim SchelstraeteMathias DevreeseJan Van BocxlaerSiska Croubels

Interactions between mycotoxins and the rumen, their possible toxicological effects on the gastrointestinal tract and their intestinal absorption in dairy cattle : an in vitro approach

Sandra DebevereMathias DevreeseSiegrid De BaereSarah De SaegerGeert HaesaertVeerle FievezSiska Croubels

Metabolic fingerprinting reveals a novel candidate biomarker for prednisolone treatment in cattle

Nathalie De ClercqJulie Vanden BusscheLieven Van MeulebroekSiska CroubelsPhilippe DelahautDieter BuystJosé MartinsJianru Stahl-ZengLynn Vanhaecke

A1 Journal Article in METABOLOMICS

Niet-steroïdale, anti-inflammatoire geneesmiddelen bij vogels: farmacokinetiek, farmacodynamiek en toxiciteit

Tess GoessensGunther AntonissenSiska CroubelsPatrick De BackerMathias Devreese

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Orale ivermectine-intoxicatie op een vleeskalverbedrijf

Hannes VermeulenBart PardonSiska CroubelsJozef VercruyssePiet Deprez

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Pharmacokinetics and electrophysiological effects of different dosages of oral sotalol in horses: preliminary results

Barbara BrouxDominique De ClercqLisse VeraGlenn Van SteenkisteAnnelies DecloedtAnneleen WatteynMathias DevreeseSiska CroubelsGunther van Loon

Pharmacokinetics of intravenously and orally administered sotalol hydrochloride in horses and effects on surface electrocardiogram and left ventricular systolic function

Barbara BrouxDominique De ClercqAnnelies DecloedtSiegrid De BaereMathias DevreeseNicky Van Der VekensSofie VenSiska CroubelsGunther van Loon

A1 Journal Article in VETERINARY JOURNAL

Plasma and intestinal concentrations of sulfadiazine-trimethoprim in pigs after (non)conventional oral and intramuscular treatment, in the context of antimicrobial resistance

Joren De SmetSiska CroubelsPatrick De BackerMathias Devreese

Polytetrafluorethyleen-intoxicatie bij vogels

Nele CaekebekeGunther AntonissenPatrick De BackerSiska Croubels

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Quantitative determination of florfenicol in pig manure by LC-MS/MS to assess the exposure of the gut microbiota to florfenicol

Joren De SmetSiska CroubelsPatrick De BackerMathias Devreese

Report from the 5th international symposium on mycotoxins and toxigenic moulds : challenges and perspectives (MYTOX) held in Ghent, Belgium, May 2016

Sarah De SaegerKris AudenaertSiska Croubels

A1 Journal Article in TOXINS

Residues of chlortetracycline, doxycycline and sulfadiazine-trimethoprim in intestinal content and feces of pigs due to cross-contamination of feed

Laura PeetersEls DaeseleireMathias DevreeseGeertrui RasschaertAnnemieke SmetJeroen DewulfMarc HeyndrickxHein ImberechtsFreddy HaesebrouckPatrick Butaye et al.

A1 Journal Article in BMC VETERINARY RESEARCH

Safety of mycotoxin binders regarding their use with veterinary medicinal products in poultry and pigs : an in vitro and pharmacokinetic approach

Thomas De MilSiska CroubelsMathias DevreesePatrick De Backer

The adsorption of veterinary drugs to mycotoxin binders in a feed-containing buffered matrix

Thomas De MilMathias DevreesePatrick De BackerSiska Croubels

The impact of deoxynivalenol on pigeon health : occurrence in feed, toxicokinetics and interaction with salmonellosis

Gunther AntonissenRoel HaesendonckMathias DevreeseNathan BroekaertElin VerbruggheSarah De SaegerKris AudenaertFreddy HaesebrouckFrank PasmansRichard Ducatelle et al.

A1 Journal Article in PLOS ONE

The potential use of piglets as human pediatric surrogate for preclinical pharmacokinetic and pharmacodynamic drug testing

Elke GasthuysTim VandecasteelePauline De BruyneJohan Vande WallePatrick De BackerPieter CornillieMathias DevreeseSiska Croubels

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

Topical acyclovir treatment of occult equine sarcoids: an in vitro and in vivo study

Maarten HaspeslaghLien TaevernierAn MaesLieven VlaminckBart De SpiegeleerSiska CroubelsAnn Martens

Topical distribution of acyclovir in normal equine skin and equine sarcoids : an in vitro study

Maarten HaspeslaghLien TaevernierAn MaesLieven VlaminckBart De SpiegeleerSiska CroubelsAnn Martens

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

2015

A validated UHPLC-MS/MS method to quantify low levels of anabolic-androgenic steroids naturally present in urine of untreated horses

Anneleen DecloedtLudovic Bailly-ChouriberryJulie Vanden BusschePatrice GarciaMarie-Agnes PopotYves BonnaireLynn Vanhaecke

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Analytical approaches to unravel the endogenous formation and biotransformation of prednisolone in livestock

Nathalie De ClercqLynn VanhaeckeJulie Vanden BusscheSiska Croubels

Assessment of mycotoxin occurrence in feed samples from the Belgian veal calf industry and the influence of roughage provision

Bonnie ValgaerenGunther AntonissenMathias DevreeseSiegrid De BaereEllen HeyndrickxSarah De SaegerPhilipp FruhmannBenedikt WarthBart PardonPiet Deprez et al.

Characterization of 27 mycotoxin binders and the relation with in vitro zearalenone adsorption at a single concentration

Thomas De MilMathias DevreeseSiegrid De BaereEric Van RanstMia EeckhoutPatrick De BackerSiska Croubels

A1 Journal Article in TOXINS

Characterization of an intravenous lipopolysaccharide inflammation model in calves with respect to the acute-phase response

Elke PlessersHeidi WynsAnneleen WatteynBart PardonPatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Chronic exposure to deoxynivalenol has no influence on the oral bioavailability of fumonisin B1 in broiler chickens

Gunther AntonissenMathias DevreeseFilip Van ImmerseelSiegrid De BaereSabine HessenbergAn MartelSiska Croubels

A1 Journal Article in TOXINS

Comparative pharmacokinetics and allometric scaling of carboplatin in different avian species

Mathias DevreeseGunther AntonissenSiegrid De BaereTom HellebuyckIsabel Van de MaeleLieze RouffaerHendrick StemckensPatrick De BackerAn MartelSiska Croubels

Comparative pharmacokinetics and allometric scaling of carboplatin in different avian species

Gunther AntonissenMathias DevreeseSiegrid De BaereTom HellebuyckIsabel Van de MaeleLieze RouffaerHendrickus JJ StemkensPatrick De BackerAn MartelSiska Croubels

A1 Journal Article in PLOS ONE

Comparative pharmacokinetics of celecoxib and mavacoxib in cockatiels (Nymphicus hollandicus)

Gunther AntonissenAn MartelTess GoessensMathias DevreeseRoel HaesendonckPatrick De BackerSiska Croubels

Comparative toxicokinetics, absolute oral bioavailability and biotransformation of zearalenone in different poultry species

Mathias DevreeseGunther AntonissenNathan BroekaertSiegrid De BaereLynn VanhaeckePatrick De BackerSiska Croubels

Comparative toxicokinetics, absolute oral bioavailability, and biotransformation of zearalenone in different poultry species

Mathias DevreeseGunther AntonissenNathan BroekaertSiegrid De BaereLynn VanhaeckePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparison of iohexol and endogenous creatinine clearance as estimators of glomerular filtration rate in piglets at different age categories

Elke GasthuysMathias DevreeseJoske MillecamPatrick De BackerSiska Croubels

Concentrations of selected antimicrobials in caecum, colon and manure of pigs due to a 3% cross-contamination of the feed and their effect on resistance in Escherichia coli

Laura PeetersAnnemieke SmetEls DaeseleireMathias DevreeseJeroen DewulfMarc HeyndrickxFreddy HaesebrouckSiska CroubelsPatrick Butaye

Deoxynivalenol in turkey poults : toxicokinetic study, absolute oral bioavailability and biotransformation

Mathias DevreeseGunther AntonissenNathan BroekaertSiegrid De BaereLynn VanhaeckePatrick De BackerSiska Croubels

Deoxynivalenol in turkey poults: toxicokinetic study, absolute oral bioavailability and comparative biotransformation with broiler chickens

Mathias DevreeseGunther AntonissenNathan BroekaertThomas De MilSiegrid De BaereLynn VanhaeckePatrick De BackerSiska Croubels

Determination of selected veterinary antimicrobials in poultry excreta by UHPLC-MS/MS, for application in Salmonella control programs

Brecht GorissenTim ReynsMathias DevreesePatrick De BackerJoris Van LocoSiska Croubels

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitative determination of gamithromycin in animal plasma, lung tissue and pulmonary epithelial lining fluid

Siegrid De BaereMathias DevreeseAnneleen WatteynHeidi WynsElke PlessersPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Development of a capillary electrophoretic method for determination of plasma clearance of iohexol in dogs and cats

Alexander HellqvistReidun HeieneSiegrid De BaereSiska CroubelsYlva Hedeland

A1 Journal Article in BIOMEDICAL CHROMATOGRAPHY

Disposition of 3- and 15-acetyl-deoxynivalenol and deoxynivalenol-3-β-D-glucoside in broiler chickens and pigs

Nathan BroekaertSiska CroubelsMathias DevreeseSarah De Saeger

Effects of xylo-oligosaccharides on broiler chicken performance and microbiota

Celine De MaesschalckVenessa EeckhautL MaertensL De LangeL MarchalC NezerSiegrid De BaereSiska CroubelsG DaubeJeroen Dewulf et al.

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Efficacy of florfenicol and gamithromycin in an Ornithobacterium rhinotracheale infection model in turkeys: a pharmacokinetic-pharmacodynamic approach

Anneleen WatteynMathias DevreeseSiegrid De BaereElke PlessersHeidi WynsPatrick De BackerSiska Croubels

Enantioselective pharmacokinetics of ketoprofen in calves after intramuscular administration of a racemic mixture

Elke PlessersAnneleen WatteynHeidi WynsBart PardonSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Evaluation of the anti-inflammatory properties of ketoprofen in bovine and porcine models using a HPLC-MS/MS multi-method

Elke PlessersSiegrid De BaereHeidi WynsAnneleen WatteynBart PardonPatrick De BackerEvelyne MeyerSiska Croubels

Exposure of Aspergillus fumigatus to T-2 toxin results in a stress response associated with exacerbation of aspergillosis in poultry

Shaoji LiMaarten DhaenensAn GarmynElin VerbrugghePascale Van RooijSarah De SaegerMia EeckhoutRichard DucatelleSiska CroubelsFreddy Haesebrouck et al.

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

Fumonisins affect the intestinal microbial homeostasis in broiler chickens, predisposing to necrotic enteritis

Gunther AntonissenSiska CroubelsFrank PasmansRichard DucatelleVenessa EeckhautMathias DevreeseMarc VerlindenFreddy HaesebrouckMia EeckhoutSarah De Saeger et al.

A1 Journal Article in VETERINARY RESEARCH

GC-C-IRMS in routine doping control practice: 3 years of drug testing data, quality control and evolution of the method

Michaël PoletPeter Van Eenoo

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Hormone and veterinary drug residue analysis in food, feed, biological and environmental matrices

Siska CroubelsEls DaeseleireSarah De SaegerPeter Van EenooLynn Vanhaecke

Editorial material

Immunomodulatory properties of gamithromycin, dexamethasone and ketoprofen in lipopolysaccharide-induced inflammation in calves

Elke PlessersSiska CroubelsPatrick De Backer

In vitro adsorption and in vivo pharmacokinetic interaction between doxycycline and frequently used mycotoxin binders in broiler chickens

Thomas De MilMathias DevreeseNathan BroekaertSophie FraeymanPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

In vivo hydrolysis and toxicokinetics of T-2 toxin and T2-glucoside in broiler chickens

Nathan BroekaertMathias DevreeseThomas De MilSophie FraeymanMarthe De BoevreSarah De SaegerPatrick De BackerSiska Croubels

In vivo porcine lipopolysaccharide inflammation models to study immunomodulation of drugs

Heidi WynsElke PlessersPatrick De BackerEvelyne MeyerSiska Croubels

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Interactions of clay-based feed additives with orally administered veterinary drugs

Thomas De MilMathias DevreeseNathan BroekaertSophie FraeymanSiegrid De BaerePatrick De BackerSiska Croubels

Intestinal concentrations of sulfadiazine-trimethoprim in pigs after (non-)conventional oral and intramuscular treatment

Joren De SmetSiska CroubelsPatrick De BackerMathias Devreese

Modified Fusarium mycotoxins unmasked: from occurrence in cereals to animal and human excretion

Nathan BroekaertMathias DevreeseSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation

Heidi WynsEvelyne MeyerElke PlessersAnneleen WatteynThomas van BergenStijn SchauvliegeSiegrid De BaereMathias DevreesePatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Multiplex analysis of pro-inflammatory cytokines in serum of Actinobacillus pleuropneumoniae-infected pigs

Heidi WynsSiska CroubelsMarjolein VandekerckhoveKristel DemeyerePatrick De BackerBruno GoddeerisEvelyne Meyer

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Mycotoxins deoxynivalenol and fumonisins alter the extrinsic component of intestinal barrier in broiler chickens

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleGeert JanssensSiegrid De BaereKonstantinos C MountzourisShengchen SuEric A WongBruno De Meulenaer et al.

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Novel insights into relationships between egg corticosterone and timing of breeding revealed by LC-MS/MS

Tom Rosendahl LarsenGraham D FairhurstSiegrid De BaereSiska CroubelsWendt MüllerLiesbeth De NeveLuc Lens

A1 Journal Article in JOURNAL OF AVIAN BIOLOGY

Oral bioavailability, hydrolysis, and comparative toxicokinetics of 3-acetyldeoxynivalenol and 15-acetyldeoxynivalenol in broiler chickens and pigs

Nathan BroekaertMathias DevreeseThomas De MilSophie FraeymanGunther AntonissenSiegrid De BaerePatrick De BackerAn VermeulenSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pharmacokinetic and pharmacodynamic properties of gamithromycin in turkey poults with respect to Ornithobacterium rhinotracheale

Anneleen WatteynMathias DevreeseSiegrid De BaereHeidi WynsElke PlessersFilip BoyenFreddy HaesebrouckPatrick De BackerSiska Croubels

A1 Journal Article in POULTRY SCIENCE

Pharmacokinetics of oral transmucosal and intramuscular dexmedetomidine combined with buprenorphine in cats

Nathalie PortersHilde De RoosterTim BosmansKris BaertMarc CherletSiska CroubelsPatrick De BackerIngeborgh Polis

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Pharmacokinetics of the selective COX-2 inhibitors celecoxib and mavacoxib in cockatiels

Gunther AntonissenMathias DevreeseSiegrid De BaereAn MartelTess GoessensRoel HaesendonckPatrick De BackerSiska Croubels

Plasma serotonin in horses undergoing surgery for small intestinal colic

Sara TorfsAn MaesCatherine DelesalleBart PardonSiska CroubelsPiet Deprez

A1 Journal Article in CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE

Predisposing effect of the mycotoxins deoxynivalenol and fumonisins on necrotic enteritis in broiler chickens

Gunther AntonissenSiska CroubelsFrank PasmansRichard DucatelleBarbara NovakSabine HessenbergerAn MartelFilip Van Immerseel

Predisposing effect of the mycotoxins deoxynivalenol and fumonisins on necrotic enteritis in broiler chickens

Gunther AntonissenSiska CroubelsAn MartelFilip Van Immerseel

Quantification of 8-α-hydroxy-mutilin as marker residue for tiamulin in rabbit tissues by high-performance liquid chromatography-mass spectrometry

Siegrid De BaereMathias DevreeseAn MaesPatrick De BackerSiska Croubels

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Quantification of ketamine and norketamine in bovine plasma by liquid chromatography–tandem mass spectrometry

Mathias DevreeseDiego RodrigoStijn SchauvliegeFrank GasthuysPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF THE IRANIAN CHEMICAL SOCIETY

Quantitative determination of tenuazonic acid in broiler chicken plasma using a validated liquid chromatography-tandem mass spectrometry method

Sophie FraeymanMathias DevreeseNathan BroekaertThomas De MilSiegrid De BaerePatrick De BackerMichael RychlikSiska Croubels

Quantitative determination of tenuazonic acid in pig and broiler chicken plasma by LC-MS/MS and its comparative toxicokinetics

Sophie FraeymanMathias DevreeseNathan BroekaertThomas De MilGunther AntonissenSiegrid De BaerePatrick De BackerMichael RychlikSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Routine kidney variables, glomerular filtration rate and urinary cystatin C in cats with diabetes mellitus, cats with chronic kidney disease and healthy cats

Dominique PaepeLiesbeth GhysPascale SmetsHervé P LefebvreSiska CroubelsSylvie Daminet

A1 Journal Article in JOURNAL OF FELINE MEDICINE AND SURGERY

Safety of mycotoxin binders in broiler feed: interaction with the oral absorption of veterinary drugs and coccidiostats

Thomas De MilMathias DevreeseNathan BroekaertSophie FraeymanSiegrid De BaerePatrick De BackerSiska Croubels

Simplified methods for estimating glomerular filtration rate in cats and for detection of cats with low or borderline glomerular filtration rate

Dominique PaepeHervé P LefebvreDidier ConcordetIngrid van HoekSiska CroubelsSylvie Daminet

A1 Journal Article in JOURNAL OF FELINE MEDICINE AND SURGERY

Study of the immunomodulatory properties of gamithromycin and dexamethasone in a lipopolysaccharide inflammation model in calves

Elke PlessersAnneleen WatteynHeidi WynsBart PardonPatrick De BackerSiska Croubels

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

The impact of deoxynivalenol on pigeon health: occurrence in feed, toxicokinetics and interaction with salmonellosis

Gunther AntonissenRoel HaesendonckMathias DevreeseNathan BroekaertElin VerbruggheSonja WeerdenburgFrank PasmansSarah De SaegerAn MartelSiska Croubels

The impact of stress on the prevalence of prednisolone in bovine urine: a metabolic fingerprinting approach

Nathalie De ClercqLieven Van MeulebroekJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The ontogeny of hepatic CYP3A, CYP2C and CYP2E enzyme activity in conventional pigs

Joske MillecamMathias DevreeseLies De BockJan Van BocxlaerElke GasthuysPatrick De BackerSiska Croubels

The use of chemotherapy in avian medicine: an international survey

Gunther AntonissenAshley ZehnderMathias DevreeseRichard DucatelleIsabel Van de MaeleAdres MontesinosHenk DecockSiska CroubelsAn Martel

Toxicokinetic study and oral bioavailability of deoxynivalenol in turkey poults, and comparative biotransformation between broilers and turkeys

Mathias DevreeseGunther AntonissenNathan BroekaertThomas De MilSiegrid De BaereLynn VanhaeckePatrick De BackerSiska Croubels

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

Unravelling the role of ruminal development in the biotransformation of deoxynivalenol and its acetylated derivatives : a comparative toxicokinetic approach

Gunther AntonissenBonnie ValgaerenMathias DevreeseSiegrid De BaereEllen HeyndrickxSarah De SaegerPhilipp FruhmannGerhard AdamPiet DeprezSiska Croubels

Use of LC–MS–MS as an alternative to currently available immunoassay methods to quantitate corticosterone in egg yolk and albumen

Siegrid De BaereTom Rosendahl LarsenMathias DevreesePatrick De BackerLiesbeth De NeveGraham FairhurstLuc LensSiska Croubels

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Validation of a quantitative method using liquid chromatography coupled to multiple mass spectrometry for thiouracil in feedstuffs used in animal husbandry

Julie KieboomsJella WautersJulie Vanden BusscheLynn Vanhaecke

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

2014

A multi-mycotoxin UHPLC-MS/MS method for the detection, quantification and identification of mycotoxins in milk replacer

Els Van PamelGunther AntonissenBonnie ValgaerenSarah De SaegerSiska CroubelsEls Daeseleire

Analysis of 12 mycotoxins in calves' milk replacer by means of UHPLC-MS/MS

Els Van PamelGunther AntonissenBonnie ValgaerenSarah De SaegerSiska CroubelsEls Daeseleire

Assessment of mycotoxin occurence in feed samples from the veal industry

Gunther AntonissenBonnie ValgaerenChristel DetavernierSarah De SaegerEls Van PamelEls DaeseleireBart PardonRichard DucatellePiet DeprezSiska Croubels

Characterization of 27 mycotoxin detoxifiers and the relation with in vitro zearalenone binding

Thomas De MilMathias DevreeseNathan BroekaertSophie FraeymanEric Van RanstSarah De SaegerMia EeckhoutGeert HaesaertPatrick De BackerSiska Croubels

Comparative efficacy of dexamethasone, ketoprofen and gamithromycin in a lipopolysaccharide-inflammation model in calves

Elke PlessersHeidi WynsAnneleen WatteynBart PardonSiegrid De BaerePatrick De BackerSiska Croubels

Comparative method validation for closantel determination in cattle and sheep milk according to European Union Volume 8 and Veterinary International Conference on Harmonization guidelines

Mathias DevreeseAn MaesSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Comparative method validation for closantel in cattle and sheep milk according to EU Volume 8 and VICH GL 49 guidelines

Mathias DevreeseAn MaesSiegrid De BaerePatrick De BackerSiska Croubels

Concentrations of selected antimicrobials in caecum, colon and manure of pigs due to a 3% cross-contamination of the feed

Laura PeetersEls DaeseleireMathias DevreeseJeroen DewulfMarc HeyndrickxFreddy HaesebrouckPatrick ButayeSiska Croubels

Detection and quantification of selected veterinary antimicrobials in poultry excreta

Brecht GorissenTim ReynsMathias DevreesePatrick De BackerJoris Van LocoSiska Croubels

Detection and quantification of the EU marker residue of tiamulin in animal tissues

Siegrid De BaereAn MaesMathias DevreesePatrick De BackerSiska Croubels

Determination of selected veterinary antimicrobials in poultry excreta

Brecht GorissenTim ReynsMathias DevreesePatrick De BackerJoris Van LocoSiska Croubels

Determination of β-lactams, fluoroquinolones, sulfonamides/trimethoprim, tetracyclines and colistin in poultry excreta by UHPLC-MS/MS

Brecht GorissenTim ReynsMathias DevreeseJoris Van LocoPatrick De BackerSiska Croubels

Development and validation of a high-resolution mass-spectrometry-based method to study the long-term stability of natural and synthetic glucocorticoids in faeces

Nathalie De ClercqJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Development and validation of an LC-MS/MS method for the toxicokinetic study of deoxynivalenol and its acetylated derivatives in chicken and pig plasma

Nathan BroekaertMathias DevreeseThomas De MilSophie FraeymanSiegrid De BaereSarah De SaegerPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Effect of administration route and dose escalation on intestinal concentrations of enro- and ciprofloxacin in broiler chickens

Mathias DevreeseGunther AntonissenSiegrid De BaerePatrick De BackerSiska Croubels

Effect of administration route and dose escalation on plasma and intestinal concentrations of enrofloxacin and ciprofloxacin in broiler chickens

Mathias DevreeseGunther AntonissenSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in BMC VETERINARY RESEARCH

Efficacy of a single bolus administration of gamithromycin against Ornithobacterium rhinotracheale infection in turkeys

Anneleen WatteynElke PlessersHeidi WynsVishwanatha Reddy Avalakuppa Papi ReddyFrank PasmansAn MartelFreddy HaesebrouckPatrick De BackerSiska Croubels

Efficacy of active carbon towards the absorption of deoxynivalenol in pigs

Mathias DevreeseGunther AntonissenPatrick De BackerSiska Croubels

A1 Journal Article in TOXINS

Faecalicoccus acidiformans gen. nov., sp. nov., isolated from the chicken caecum, and reclassification of Streptococcus pleomorphus (Barnes et al. 1977), Eubacterium biforme (Eggerth 1935) and Eubacterium cylindroides (Cato et al. 1974) as Faecalicoccus pleomorphus comb. nov., Holdemanella biformis gen. nov., comb. nov. and Faecalitalea cylindroides gen. nov., comb. nov., respectively, within the family Erysipelotrichaceae

Celine De MaesschalckFilip Van ImmerseelVenessa EeckhautSiegrid De BaereMargo CnockaertSiska CroubelsFreddy HaesebrouckRichard DucatellePeter Vandamme

A1 Journal Article in INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Het gebruik van Synacthen

Anneleen WatteynSiska CroubelsSylvie Daminet

Editorial material

Immunomodulation of veterinary drugs on lipopolysaccharide-induced inflammation in pigs : influence of gamithromycin and ketoprofen on the acute phase response

Heidi WynsSiska CroubelsPatrick De BackerEvelyne Meyer

Influence of gamithromycin and ketoprofen on the acute phase response in LPS-challenged pigs

Heidi WynsEvelyne MeyerElke PlessersAnneleen WatteynSiegrid De BaereThomas van BergenStijn SchauvliegePatrick De BackerSiska Croubels

Intestinal concentrations of enrofloxacin after different dosage regimens in broiler chickens

Mathias DevreeseSiegrid De BaerePatrick De BackerSiska Croubels

Is it safe to focus exclusively on non-conjugated toxins?: toxicokinetics, bioavailability and in vivo hydrolysis of 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in chickens and pigs

Nathan BroekaertMathias DevreeseThomas De MilSophie FraeymanSarah De SaegerSiska Croubels

Is it safe to focus exclusively on non-conjugated toxins?: toxicokinetics, oral bioavailability and in vivo hydrolysis of 3ADON and 15ADON in broiler chickens

Nathan BroekaertMathias DevreeseThomas De MilSophie FraeymanSarah De SaegerSiska Croubels

Modulation of intestinal transport of nutrients following dietary exposure to Fusarium mycotoxins in broiler chickens

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckMarc VerlindenSabine HessenbergerShengchen SuEric WongAn Martel et al.

Pharmacokinetics of florfenicol in turkey poults

Anneleen WatteynMathias DevreeseSiegrid De BaerePatrick De BackerSiska Croubels

Pharmacokinetics of gamithromycin after intravenous and subcutaneous administration in pigs

Heidi WynsEvelyne MeyerElke PlessersAnneleen WatteynSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Pharmacokinetics of gamithromycin in turkey plasma and lung tissue

Anneleen WatteynMathias DevreeseSiegrid De BaereElke PlessersHeidi WynsPatrick De BackerSiska Croubels

Pilot toxicokinetic study and absolute oral bioavailability of the Fusarium mycotoxin enniatin B1 in pigs

Mathias DevreesePatrick De BackerSiska Croubels

Pilot toxicokinetic study and absolute oral bioavailability of the Fusarium mycotoxin enniatin B1 in pigs

Mathias DevreeseNathan BroekaertThomas De MilSophie FraeymanPatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Sotalol hydrochloride as an oral anti-arrhythmic in the horse

Barbara BrouxNicky Van Der VekensAnnelies DecloedtDominique De ClercqSiska CroubelsGunther van Loon

Tetracycline, sulfonamide and trimethoprim resistance genes and integrons in Escherichia coli

Laura PeetersMA ArgudínSiska CroubelsEls DaeseleireJeroen DewulfMarc HeyndrickxFreddy HaesebrouckPatrick Butaye

The effect of morphine on regional cerebral blood flow measured by 99mTc-ECD SPECT in dogs

Antita AdriaensKathelijne PeremansTim WaelbersEva VandermeulenSiska CroubelsLuc DuchateauAndré DobbeleirKurt AudenaertJos EerselsSimon Vermeire et al.

A1 Journal Article in PLOS ONE

The effect of prolonged exposure to morphine on canine cerebral 5-HT2A receptors measured with 123I-R91150 SPECT

Antita AdriaensIngeborgh PolisSimon VermeireTim WaelbersSiska CroubelsLuc DuchateauSylvia Van DorpeJos EerselsBart De SpiegeleerKathelijne Peremans

A1 Journal Article in EUROPEAN NEUROPSYCHOPHARMACOLOGY

The effects of feed-borne Fusarium mycotoxins and glucomannan in turkey poults based on specific and non-specific parameters

Mathias DevreeseGeorge N GirgisSi-Trung TranSiegrid De BaerePatrick De BackerSiska CroubelsTrevor K Smith

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

The impact of deoxynivalenol and fumonisins on mRNA expression of intestinal and hepatic biotransformation enzymes and drug transporter systems in broiler chickens

Gunther AntonissenMathias DevreeseAn MartelFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckPatrick De BackerSiska Croubels

The impact of Fusarium mycotoxins on human and animal host susceptibility to infectious diseases

Gunther AntonissenAn MartelFrank PasmansRichard DucatelleElin VerbruggheVirginie VandenbrouckeShaoji LiFreddy HaesebrouckFilip Van ImmerseelSiska Croubels

A1 Journal Article in TOXINS

The mycotoxin deoxynivalenol predisposes for the development of Clostridium perfringens-induced necrotic enteritis in broiler chickens

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenGeert JanssensVenessa EeckhautMia Eeckhout et al.

A1 Journal Article in PLOS ONE

Underestimation of deoxynivalenol exposure: fate of 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in pigs

Nathan BroekaertMathias DevreeseThomas De MilSophie FraeymanGunther AntonissenSiska Croubels

Unravelling the disposition of the Alternaria mycotoxin tenuazonic acid: a toxicokinetic study in piglets

Sophie FraeymanMathias DevreeseNathan BroekaertThomas De MilMichael RychlikSiska Croubels

Unravelling the disposition of the Alternaria mycotoxin tenuazonic acid: a toxicokinetic study in pigs and broiler chickens

Sophie FraeymanMathias DevreeseNathan BroekaertThomas De MilSiegrid De BaerePatrick De BackerMichael RychlikSiska Croubels

Use of Monte Carlo simulation to determine pharmacodynamic cutoffs of amoxicillin to establish a breakpoint for antimicrobial susceptibility testing in pigs

Julien F ReyCéline M LaffontSiska CroubelsPatrick De BackerClaudine ZemirlineEric BousquetJérôme GuyonnetAude A FerranAlain Bousquet-MelouPierre-Louis Toutain

A1 Journal Article in AMERICAN JOURNAL OF VETERINARY RESEARCH

2013

A validated analytical method to study the long-term stability of natural and synthetic glucocorticoids in livestock urine using ultra-high performance liquid chromatography coupled to Orbitrap-high resolution mass spectrometry

Nathalie De ClercqJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Acute hemorrhagic syndrome by bracken poisoning in cattle in Belgium

Elke PlessersBart PardonPiet DeprezPatrick De BackerSiska Croubels

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents

Mathias DevreeseFrank PasmansPatrick De BackerSiska Croubels

A1 Journal Article in TOXICOLOGY IN VITRO

Characterization of in vitro intestinal absorption of veterinary drugs and coccidiostats in the presence of mycotoxin detoxifiers using a porcine intestinal epithelial cell line: outline of the study

Thomas De MilMathias DevreeseAnn OsselaereElin VerbruggheJoline GoossensFrank PasmansPatrick De BackerSiska Croubels

Chronic exposure to the mycotoxin deoxynivalenol affects the intestinal barrier function in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckAnn OsselaereLeen TimbermontMarc VerlindenMia EeckhoutEvelyne Delezie et al.

Chronic exposure to the mycotoxin T-2 promotes oral absorption of chlortetracycline in pigs

Joline GoossensMathias DevreeseFrank PasmansAnn OsselaereSiegrid De BaereElin VerbruggheFreddy HaesebrouckPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Clinical efficacy of florfenicol administered in the drinking water against Ornithobacterium rhinotracheale in turkeys housed in different environmental conditions: a pharmacokinetic/pharmacodynamic approach

Anneleen WatteynElisa RussoAn GarmynSiegrid De BaereFrank PasmansAn MartelFreddy HaesebrouckClara MontesissaPatrick De BackerSiska Croubels

A1 Journal Article in AVIAN PATHOLOGY

Comparative carboplatin pharmacokinetics in four different avian species

Gunther AntonissenSiska CroubelsSiegrid De BaereIsabel Van de MaeleLieze RouffaerTom HellebuyckAn Martel

Deoxynivalenol impairs hepatic and intestinal gene expression of selected oxidative stress, tight junction and inflammation proteins in broiler chickens, but addition of an adsorbing agent shifts the effects to the distal parts of the small intestine

Ann OsselaereRegiane SantosVeerle HautekietPatrick De BackerKoen ChiersRichard DucatelleSiska Croubels

A1 Journal Article in PLOS ONE

Deoxynivalenol predisposes for necrotic enteritis by affecting the intestinal barrier in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenGeert JanssensMia EeckhoutSarah De Saeger et al.

Determination of the Alternaria mycotoxins alternariol, alternariol monomethyl ether and tenuazonic acid in animal plasma using LC-MS/MS: preliminary results

Sophie FraeymanSiegrid De BaereMathias DevreeseNathan BroekaertPatrick De BackerSiska Croubels

Development and validation of an LC-MS/MS method for the determination of DON, 3A-DON and 15A-DON in chicken plasma

Nathan BroekaertMathias DevreeseThomas De MilAnn OsselaereSophie FraeymanSarah De SaegerSiska Croubels

Development of a cytometric bead array screening tool for the simultaneous detection of pro-inflammatory cytokines in porcine plasma

Heidi WynsSiska CroubelsKristel DemeyereAnneleen WatteynPatrick De BackerEvelyne Meyer

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Development of a HPLC–UV method for the quantitative determination of four short-chain fatty acids and lactic acid produced by intestinal bacteria during in vitro fermentation

Siegrid De BaereVenessa EeckhautMarjan SteppeCeline De MaesschalckPatrick De BackerFilip Van ImmerseelSiska Croubels

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Development of a rapid, robust and economic method for the quantitative determination of colistin in poultry manure

Brecht GorissenTim ReynsPatrick De BackerJoris Van LocoSiska Croubels

Development of cut-off exo-iohexol, creatinine, endo-iohexol concentrations at three time points after intravenous iohexol and creatinine injection to predict low glomerular filtration rate in cats

Dominique PaepeHP LefebvreD ConcordetIngrid van HoekSiska CroubelsSylvie Daminet

Development of in vitro and in vivo models for testing the efficacy of mycotoxin detoxifying agents and their possible interaction with oral absorption of veterinary drugs

Mathias DevreeseSiska CroubelsPatrick De Backer

Different methods to counteract mycotoxin production and its impact on animal health

Mathias DevreesePatrick De BackerSiska Croubels

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Effects of Fusarium mycotoxins on the pathogenesis of necrotic enteritis in broilers

Gunther AntonissenSiska CroubelsFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenGeert JanssensMia EeckhoutSarah De Saeger et al.

Effects of T-2 toxin on the interaction between chicken macrophages and Aspergillus fumigatus conidia

Shaoji LiFrank PasmansSiska CroubelsElin VerbruggheLieven Van WaeyenbergheZhen YangFreddy HaesebrouckAn Martel

Efficacy testing of a glucomannan mycotoxin binder towards the effects of feed-borne Fusarium mycotoxins in turkey poults based on specific and unspecific parameters

Mathias DevreeseGeorge GirgisSi-Trung TranSiegrid De BaerePatrick De BackerSiska CroubelsTrevor K Smith

Feline pharmacokinetics of oral transmucosal and intramuscular dexmedetomidine and buprenorphine

Nathalie PortersHilde De RoosterTim BosmansKris BaertMarc CherletSiska CroubelsPatrick De BackerIngeborgh Polis

Field study to identify frequently used mycotoxin detoxifiers in Belgium

Thomas De MilMia EeckhoutEric Van RanstPatrick De BackerSiska Croubels

Hepatic and intestinal CYP3A expression and activity in broilers

Ann OsselaereLies De BockVenessa EeckhautPatrick De BackerJan Van BocxlaerKoen BousserySiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Impact of deoxynivalenol on oral bioavailability of fumonisins in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleMathias DevreeseSiegrid De BaereFreddy HaesebrouckMia EeckhoutSarah De SaegerSabine Hessenberger et al.

Influence of deoxynivalenol and T-2 toxin on the intestinal barrier and liver function in broiler chickens

Ann OsselaereSiska CroubelsPatrick De Backer

Influence of deoxynivalenol and T-2 toxin on the oral bioavailability of antibiotics in pigs

Joline GoossensSiska CroubelsFrank PasmansPatrick De Backer

Influence of different housing conditions on the clinical efficacy of florfenicol administered in the drinking water against Ornithobacterium rhinotracheale in turkeys

Anneleen WatteynElisa RussoAn GarmynSiegrid De BaereFrank PasmansAn MartelFreddy HaesebrouckClara MontesissaPatrick De BackerSiska Croubels

Influence of mycotoxin contamination on intestinal protein availability for clostridial proliferation

Gunther AntonissenSiska CroubelsFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenGeert JanssensSabine HessenbergerAn Martel et al.

Metabolomic profiling of the glucocorticoid status of Holstein-Friesian cows by U-HPLC-HR-Orbitrap MS upon administration of prednisolone

Nathalie De ClercqJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

Mycotoxin contamination in commercial parakeet feeds

Shaoji LiEmmanuel Njumbe EdiageSarah De SaegerLieven Van WaeyenbergheAn GarmynMarc VerlindenRichard DucatelleSiska CroubelsFreddy HaesebrouckFrank Pasmans et al.

Occurrence and pathology of mycotoxins in commercial parrot feeds

Shaoji LiEmmanuel Njumbe EdiageSarah De SaegerLieven Van WaeyenbergheAn GarmynMarc VerlindenRichard DucatelleSiska CroubelsFreddy HaesebrouckFrank Pasmans et al.

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

Overview of the most important mycotoxins for the pig and poultry husbandry

Mathias DevreesePatrick De BackerSiska Croubels

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Pharmacokinetics of dexamethasone after intravenous and intramuscular administration in broiler chickens

Anneleen WatteynHeidi WynsElke PlessersElisa RussoSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY JOURNAL

Pharmacokinetics of dexamethasone after intravenous and intramuscular administration in pigs

Heidi WynsEvelyne MeyerAnneleen WatteynElke PlessersSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY JOURNAL

Pharmacokinetics of gamithromycin after intravenous and subcutaneous administration in broiler chickens

Anneleen WatteynElke PlessersHeidi WynsSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in POULTRY SCIENCE

Quantitative determination of the Fusarium mycotoxins beauvericin, enniatin A, A1, B and B1 in pig plasma using high performance liquid chromatography-tandem mass spectrometry

Mathias DevreeseSiegrid De BaereAnn OsselaereThomas De MilNathan BroekaertPatrick De BackerSiska Croubels

Quantitative determination of the Fusarium mycotoxins beauvericin, enniatin A, A1, B and B1 in pig plasma using high performance liquid chromatography–tandem mass spectrometry

Mathias DevreeseSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in TALANTA

Routine kidney parameters, glomerular filtration rate and urinary cystatin C in cats with diabetes mellitus, cats with chronic kidney disease and healthy cats

Dominique PaepeLiesbeth GhysPascale SmetsH LefebvreSiska CroubelsJoris DelangheEvelyne MeyerSylvie Daminet

T-2 toxin impairs antifungal activities of chicken macrophages against Aspergillus fumigatus conidia but promotes the pro-inflammatory responses

Shaoji LiFrank PasmansSiska CroubelsElin VerbruggheLieven Van WaeyenbergheZhen YangFreddy HaesebrouckAn Martel

A1 Journal Article in AVIAN PATHOLOGY

The impact of mycotoxin co-occurence on necrotic enteritis in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenMia EeckhoutSarah De SaegerEvelyne Delezie et al.

The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs

Joline GoossensLies De BockAnn OsselaereElin VerbruggheMathias DevreeseKoen BousseryJan Van BocxlaerPatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

The use of intratumoral chemotherapy in an integumentary squamous cell carcinoma in a cockatiel (Nymphicus hollandicus)

Gunther AntonissenIsabel Van de MaeleRichard DucatelleLien De CoomanAn GarmynTom HellebuyckSiska CroubelsAn Martel

Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic biotransformation enzymes and drug transporter systems in broiler chickens

Ann OsselaereShaoji LiLies De BockMathias DevreeseJoline GoossensVirginie VandenbrouckeJan Van BocxlaerKoen BousseryFrank PasmansAn Martel et al.

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Ann OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in FOOD AND CHEMICAL TOXICOLOGY

2012

A modified glucomannan mycotoxin-adsorbing agent counteracts the reduced weight gain and diminishes cecal colonization of Salmonella Typhimurium in T-2 toxin exposed pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeJoline GoossensPatrick De BackerMia EeckhoutSarah De SaegerFilip BoyenBregje LeymanAlexander Van Parys et al.

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Batrachochytrium dendrobatidis zoospore secretions rapidly disturb intercellular junctions in frog skin

Melanie BrutynKatharina D'HerdeMaarten DhaenensPascale Van RooijElin VerbruggheAlex D HyattSiska CroubelsDieter DeforceRichard DucatelleFreddy Haesebrouck et al.

A1 Journal Article in FUNGAL GENETICS AND BIOLOGY

Comparative analysis of serotonin in equine plasma with liquid chromatography–tandem mass spectrometry and enzyme-linked immunosorbent assay

Sara TorfsAn MaesCatherine DelesallePiet DeprezSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

Deoxynivalenol predisposes for the development of necrotic enteritis in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenJeroen DewulfMia EeckhoutSarah De Saeger et al.

Development of a cytometric bead array screening tool for the simultaneous detection of pro-inflammatory cytokines and acute phase proteins in porcine plasma

Heidi WynsSiska CroubelsKristel DemeyereAnneleen WatteynPatrick De BackerEvelyne Meyer

Development of a liquid-chromatography tandem mass spectrometry and ultra-high-performance liquid chromatography high-resolution mass spectrometry method for the quantitative determination of zearalenone and its major metabolites in chicken and pig plasma

Siegrid De BaereAnn OsselaereMathias DevreeseLynn VanhaeckePatrick De BackerSiska Croubels

A1 Journal Article in ANALYTICA CHIMICA ACTA

Double trouble : interactions between deoxynivalenol and the pathogenesis of Salmonella Typhimurium infections in pigs

Virginie VandenbrouckeSiska CroubelsFrank Pasmans

Effect of T-2 toxin and a yeast-extract feed additive on the oral bioavailability of chlortetracycline in pigs

Joline GoossensFrank PasmansVirginie VandenbrouckeElin VerbruggheMathias DevreeseAnn OsselaereSiegrid De BaereFreddy HaesebrouckPatrick De BackerSiska Croubels

Efficacy and safety testing of mycotocoxin-detoxifying agents in broilers following the European Food Safety Authority guidelines

Ann OsselaereMathias DevreeseAnneleen WatteynVirginie VandenbrouckeJoline GoossensVeerle HautekietMia EeckhoutSarah De SaegerSiegrid De BaerePatrick De Backer et al.

A1 Journal Article in POULTRY SCIENCE

Endogenous formation of glucocorticoids in livestock urine: a stability study

Nathalie De ClercqJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

Epidemiology of animal poisonings in Europe

Francesca CaloniPhilippe BernySiska CroubelsMagda SachanaRaimon Guitart

Bookchapter in Veterinary toxicology : basic and clinical principles

Evaluation of renal function in dogs with diabetes mellitus

Sofie MarynissenLiesbeth GhysDominique PaepeSiska CroubelsEvelyne MeyerSylvie DaminetPascale Smets

Evaluation of the antiviral activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl]guanine (A-5021) against equine herpesvirus type 1 in cell monolayers and equine nasal mucosal explants

Sarah GlorieuxAnnelies VandekerckhoveNesya GorisXiaoyun YangLennert SteukersGerlinde Van de WalleSiska CroubelsJohan NeytsHans Nauwynck

A1 Journal Article in ANTIVIRAL RESEARCH

Germ tube mediated invasion of Batrachochytrium dendrobatidis in amphibian skin is host dependent

Pascale Van RooijAn MartelKatharina D'HerdeMelanie BrutynSiska CroubelsRichard DucatelleFreddy HaesebrouckFrank Pasmans

A1 Journal Article in PLOS ONE

Gli effetti delle micotossine sull'immunità nelle specie avicole

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleAn MartelSiska Croubels

Hypercortisolism affects glomerular and tubular function in dogs

Pascale SmetsHP LefebvreHS KooistraEvelyne MeyerSiska CroubelsBert MaddensSophie VandenabeeleJimmy SaundersSylvie Daminet

A1 Journal Article in VETERINARY JOURNAL

In vitro and in vivo safety testing of mycotoxin detoxifying agents

Mathias DevreeseJoline GoossensAnn OsselaereVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

Influence of dexamethasone and gamithromycin on the acute phase response in LPS-challenged calves

Elke PlessersAnneleen WatteynHeidi WynsBart PardonPatrick De BackerSiska Croubels

Influence of mycotoxins and a mycotoxin adsorbing agent on the oral bioavailability of commonly used antibiotics in pigs

Joline GoossensVirginie VandenbrouckeFrank PasmansSiegrid De BaereMathias DevreeseAnn OsselaereElin VerbruggheFreddy HaesebrouckSarah De SaegerMia Eeckhout et al.

A1 Journal Article in TOXINS

Influence of P-glycoprotein modulation on plasma concentrations and pharmacokinetics of orally administered prednisolone in dogs

Sara Van der HeydenSiska CroubelsCaroline GadeyneRichard DucatelleSylvie DaminetHugo Murua EscobarKatharina SterenczakIngeborgh PolisStijn SchauvliegeMyriam Hesta et al.

A1 Journal Article in AMERICAN JOURNAL OF VETERINARY RESEARCH

Interaction between tylosin and bentonite clay from a pharmacokinetic perspective

Mathias DevreeseAnn OsselaereJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in VETERINARY JOURNAL

Interaction between tylosin and bentonite clay from a pharmacokinetic perspective

Mathias DevreeseAnn OsselaereJoline GoossensSiegrid De BaerePatrick De BackerSiska Croubels

Long-term follow-up of renal function in dogs after treatment for ACTH-dependent hyperadrenocorticism

Pascale SmetsHervé LefebvreBP MeijSiska CroubelsEvelyne MeyerIsabel Van de MaeleSylvie Daminet

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

Long-term follow-up of renal function in dogs with ACTH-dependent hyperadrenocorticism

Pascale SmetsHP LefebvreBP MeijSiska CroubelsEvelyne MeyerIsabel Van de MaeleSylvie Daminet

Modulation of interactions of Salmonella Typhimurium with pigs by stress and T-2 toxin

Elin VerbruggheFrank PasmansSiska CroubelsFreddy Haesebrouck

Mycotoxines: interactie tussen deoxynivalenol (DON) en een Salmonella Typhimurium infectie in varkens

Virginie VandenbrouckeElin VerbruggheFrank PasmansFreddy HaesebrouckPatrick De BackerSiska Croubels

Myth and reality of antimicrobial selection for livestock

Patrick De BackerSiska CroubelsMathias Devreese

New bolus models for in vivo efficacy testing of mycotoxin detoxifying agents in relation to EFSA guidelines, assessed using deoxynivalenol in broiler chickens

Mathias DevreeseAnn OsselaereJoline GoossensVirginie VandenbrouckeSiegrid De BaereMia EeckhoutPatrick De BackerSiska Croubels

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

New insights in the early pathogenesis of infections with the fungal pathogen Batrachochytrium dendrobatidis in amphibians

Pascale Van RooijAn MartelKatharina D'HerdeSiska CroubelsFreddy HaesebrouckFrank Pasmans

Pharmacokinetics and oral bioavailability of a new developed florfenicol drinking water formulation in veal calves, pigs and broilers

Siska CroubelsMathias DevreeseBrenda VermeulenPatrick De Backer

Pharmacokinetics of dexamethasone in broiler chickens

Anneleen WatteynHeidi WynsElke PlessersSiegrid De BaerePatrick De BackerSiska Croubels

Pharmacokinetics of dexamethasone in pigs

Heidi WynsEvelyne MeyerAnneleen WatteynElke PlessersSiegrid De BaerePatrick De BackerSiska Croubels

Plackett-Burman design as a tool to develop a generic extraction for U-HPLC-Orbitrap-MS analysis of glucocorticoids in livestock urine

Nathalie De ClercqJulie Vanden BusscheSiska CroubelsPhilippe DelahautLynn Vanhaecke

Plasma serotonin and surgical small intestinal colic in horses

Sara TorfsAn MaesCatherine DelesalleSiska CroubelsPiet Deprez

Porcine intestinal epithelial barrier disruption by the Fusarium mycotoxins deoxynivalenol and T-2 toxin promotes transepithelial passage of doxycycline and paromomycin

Joline GoossensFrank PasmansElin VerbruggheVirginie VandenbrouckeSiegrid De BaereEvelyne MeyerFreddy HaesebrouckPatrick De BackerSiska Croubels

A1 Journal Article in BMC VETERINARY RESEARCH

Quantitative analysis of an anti-viral immune escape compound ML-7 in feline plasma using ultra performance liquid chromatography/electrospray ionization mass spectrometry

Marc CherletSabine GleichHannah DewerchinHans NauwynckSylvie DaminetPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Quantitative determination of exo- and endo-iohexol in canine and feline samples using high performance liquid chromatography with ultraviolet detection

Siegrid De BaerePascale SmetsNatalie FinchReidun HeienePatrick De BackerSylvie DaminetSiska Croubels

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quantitative determination of several toxicological important mycotoxins in pig plasma using multi-mycotoxin and analyte-specific high performance liquid chromatography–tandem mass spectrometric methods

Mathias DevreeseSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Quantitative determination of zearalenone and its major metabolites in animal plasma using LC-MS/MS and (U)HPLC-HR-MS detection

Siegrid De BaereAnn OsselaereMathias DevreesePatrick De BackerSiska Croubels

Renal function and morphology in aged Beagle dogs before and after hydrocortisone administration

Pascale SmetsHervé P LefebvreLuca AresuSiska CroubelsHendrik HaersKoen PironEvelyne MeyerSylvie Daminet

A1 Journal Article in PLOS ONE

Residues of sulfadiazine and doxycycline in broiler liver and muscle tissue due to cross-contamination of feed

Valerie VandenbergeEvelyne DelezieGerard HuyghebaertPhilippe DelahautEls DaeseleireSiska Croubels

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Residues of sulfadiazine and doxycycline in egg matrices due to cross-contamination in the feed of laying hens and the possible correlation with physicochemical, pharmacokinetic and physiological parameters

Valerie VandenbergeEvelyne DelezieGerard HuyghebaertPhilippe DelahautPatrick De BackerSiska Croubels

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions

Elin VerbruggheVirginie VandenbrouckeMaarten DhaenensNeil ShearerJoline GoossensSarah De SaegerMia EeckhoutKatharina D'HerdeArthur ThompsonDieter Deforce et al.

A1 Journal Article in VETERINARY RESEARCH

The mycotoxin deoxynivalenol predisposes for the development of necrotic enteritis in broilers

Gunther AntonissenSiska CroubelsFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenJeroen DewulfMia EeckhoutSarah De Saeger et al.

The mycotoxin deoxynivalenol predisposes for the development of necrotic enteritis in broilers

Gunther AntonissenFilip Van ImmerseelFrank PasmansRichard DucatelleFreddy HaesebrouckLeen TimbermontMarc VerlindenJeroen DewulfMia EeckhoutSarah De Saeger et al.

Toxic effects of dietary exposure to T-2 toxin on intestinal and hepatic CYP450 in broilers

Ann OsselaereShaoji LiLies De BockMathias DevreeseJoline GoossensVirginie VandenbrouckeFrank PasmansAn MartelPatrick De BackerSiska Croubels

Toxicokinetic study of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens

Ann OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckeSiegrid De BaerePatrick De BackerSiska Croubels

Transfer of cross-contamination levels of coccidiostats, antibiotics and anthelmintics from feed to poultry matrices

Valerie VandenbergeSiska CroubelsE Daeseleire

Transfer of flubendazole and tylosin at cross contamination levels in the feed to egg matrices and distribution between egg yolk and egg white

Valerie VandenbergeEvelyne DeleziePhilippe DelahautGilles PierretPatrick De BackerEls DaeseleireSiska Croubels

A1 Journal Article in POULTRY SCIENCE

Transfer of flubendazole and tylosin from feed at cross-contamination levels to various poultry matrices

Valerie VandenbergeEvelyne DeleziePhilippe DelahautGilles PierretPatrick De BackerEls DaeseleireSiska Croubels

A1 Journal Article in POULTRY SCIENCE

Transfer of the coccidiostats monensin and lasalocid from feed at cross-contamination levels to whole egg, egg white and egg yolk

Valerie VandenbergeEvelyne DelezieGerard HuyghebaertPhilippe DelahautGilles PeirretPatrick De BackerSiska CroubelsEls Daeseleire

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Veterinary drug residues in foods

Siska CroubelsEls Daeseleire

Bookchapter in Chemical contaminants and residues in food

2011

Butyrate production in phylogenetically diverse Firmicutes isolated from the chicken caecum

Venessa EeckhautFilip Van ImmerseelSiska CroubelsSiegrid De BaereFreddy HaesebrouckRichard DucatellePetra LouisPeter Vandamme

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

Chiral inversion of R(-) to S(+) ketoprofen in pigs

Eva NeirinckxSiska CroubelsJean Paul RemonMathias DevreesePatrick De BackerChris Vervaet

A1 Journal Article in VETERINARY JOURNAL

Combined effects of deoxynivalenol and Salmonella Typhimurium on intestinal inflammation in the pig

Virginie VandenbrouckeFrank PasmansAn MartelElin VerbruggheJoline GoossensKim Van DeunFilip BoyenPatrick De BackerFreddy HaesebrouckSiska Croubels

Cytotoxic effects of the Fusarium mycotoxins deoxynivalenol, T2-toxin, fumonisin B1 and zearalenone on intestinal porcine epithelial cells derived from the jejunum

Joline GoossensFrank PasmansVirginie VandenbrouckeEvelyne MeyerFreddy HaesebrouckPatrick De BackerSiska Croubels

Double benefit: a modified glucomannan mycotoxin-adsorbing agent counteracts T-2 toxin related reduced weight gain and limits Salmonella Typhimurium infections in pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeJoline GoossensPatrick De BackerMia EeckhoutSarah De SaegerFilip BoyenBregje LeymanAlexander Van Parys et al.

Double trouble: the interaction between the mycotoxin deoxynivalenol and salmonellosis in the pig

Virginie VandenbrouckeSiska CroubelsElin VerbruggheJoline GoossensFreddy HaesebrouckPatrick De BackerFrank Pasmans

Een gewijzigde glucomannaan mycotoxine binder en T2-toxine in het voeder verminderen de kolonisatie van Salmonella Typhimurium in varkens

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerBregje LeymanAlexander Van ParysFilip Boyen et al.

Effects of the mycotoxins deoxynivalenol and T-2 toxin on the pathogenesis of a Salmonella TYphimurium infection in pigs

Virginie VandenbrouckeElin VerbruggheSiska CroubelsAn MartelJoline GoossensKim Van DeunFilip BoyenArthur ThompsonNeil ShearerSarah De Saeger et al.

Efficacy and safety testing of mycotoxin-detoxifying agents in broilers following the EFSA guidelines

Ann OsselaereAnneleen WatteynSiegrid De BaereSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

Feasibility of the Ussing chamber technique for the determination of in vitro jejunal permeability of passively absorbed compounds in different animal species

Eva NeirinckxChris VervaetJoris MichielsStefaan De SmetWim Van Den BroeckJean Paul RemonPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Glomerular filtration rate estimation by use of a correction formula for slope-intercept plasma iohexol clearance in cats

Natalie C FinchHarriet M SymeJonathan ElliottAdrien M PetersRobert GerritsenSiska CroubelsReidun Heiene

A1 Journal Article in AMERICAN JOURNAL OF VETERINARY RESEARCH

Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa

Sarah GlorieuxClaus BachertHerman FavoreelAnnelies VandekerckhoveLennert SteukersAnamaria RekeckiWim Van Den BroeckJoline GoossensSiska CroubelsReginald F Clayton et al.

A1 Journal Article in PLOS ONE

In vivo efficacy testing of mycoxotoxin binders in poultry by means of a toxicokinetic study according to EFSA guidelines

Mathias DevreeseAnn OsselaereSiegrid De BaerePatrick De BackerSiska Croubels

Influence of mycotoxin detoxifying agents on the plasma pharmacokinetics and tissue residues of amoxicillin and oxytetracycline in poultry

Ann OsselaereJoline GoossensSiegrid De BaereSarah De SaegerMia EeckhoutPatrick De BackerSiska Croubels

Mycotoxinen en Salmonella in de varkenshouderij

Elin VerbruggheJolien GoossensFrank PasmansPatrick De BackerFreddy HaesebrouckSiska Croubels

Nieuwe Europese (EFSA) richtlijnen om de efficaciteit van mycotoxine binders en modifiers aan te tonen

Mathias DevreeseAnn OsselaereJoline GoossensSiegrid De BaerePatrick De BackerSiska Croubels

Quantitative determination of T-2 toxin, HT-2 toxin, deoxynivalenol and deepoxy-deoxynivalenol in animal body fluids using LC-MS/MS detection

Siegrid De BaereJoline GoossensAnn OsselaereMathias DevreeseVirginie VandenbrouckePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Species comparison of enantioselective oral bioavailability and pharmacokinetics of ketoprofen

Eva NeirinckxSiska CroubelsSandra De BoeverJean Paul RemonTim BosmansSylvie DaminetPatrick De BackerChris Vervaet

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Stress induced Salmonella Typhimurium recrudescence in pigs coincides with cortisol induced increased intracellular proliferation in macrophages

Elin VerbruggheFilip BoyenAlexander Van ParysKim Van DeunSiska CroubelsArthur ThompsonNeil ShearerBregje LeymanFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY RESEARCH

Study of the immunomodulating properties of drugs in a lipopolysaccharide-inflammation model in calves

Elke PlessersHeidi WynsAnneleen WatteynBart PardonPatrick De BackerSiska Croubels

T-2 toxin alters host-pathogen interactions of Salmonella Typhimurium in pigs

Elin VerbruggheSiska CroubelsVirginie VandenbrouckeMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerArthur ThompsonNeil ShearerFilip Boyen et al.

T-2 toxin causes decreased intestinal colonization of Salmonella Typhimurium in pigs associated with altered gene expression

Elin VerbruggheVirginie VandenbrouckeSiska CroubelsMia EeckhoutSarah De SaegerJoline GoossensPatrick De BackerArthur ThompsonNeil ShearerBregje Leyman et al.

The influence of modulation of P-glycoprotein and/or cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs

Caroline GadeyneS Van der HeydenFrank GasthuysSiska CroubelsStijn SchauvliegeIngeborgh Polis

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

The mycotoxin deoxynivalenol potentiates intestinal inflammation by Salmonella Typhimurium in porcine ileal loops

Virginie VandenbrouckeSiska CroubelsAn MartelElin VerbruggheJoline GoossensKim Van DeunFilip BoyenArthur ThompsonNeil ShearerPatrick De Backer et al.

A1 Journal Article in PLOS ONE

2010

Animal poisoning in Europe, part 1: farm livestock and poultry

Raimon GuitartSiska CroubelsFrancesca CaloniMagda SachanaFranca DavanzoVirginie VandenbrouckePierre Berny

A1 Journal Article in VETERINARY JOURNAL

Animal poisoning in Europe, part 2: companion animals

Philippe BernyFrancesca CaloniSiska CroubelsMagda SachanaVirginie VandenbrouckeFranca DavanzoRaimon Guitart

A1 Journal Article in VETERINARY JOURNAL

Animal poisoning in Europe, part 3: wildlife

Raimon GuitartMagda SachanaFrancesca CaloniSiska CroubelsVirginie VandenbrouckePhilippe Berny

A1 Journal Article in VETERINARY JOURNAL

Animal poisonings in Belgium: a review of the past decade

Virginie VandenbrouckeHenk Van PeltPatrick De BackerSiska Croubels

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Comparison of plasma exo-iohexol, endo-iohexol and creatinine clearances in cats with low, normal and high glomerular filtration rates

Dominique PaepeIngrid van HoekHP LefebvreMiguel CamposSiska CroubelsSylvie Daminet

Deoxynivalenol alters the interactions of Salmonella Typhimurium with porcine intestinal epithelial cells and macrophages

Virginie VandenbrouckeFrank PasmansElin VerbruggheJoline GoossensFreddy HaesebrouckPatrick De BackerSiska Croubels

Development of a quantitative method for the determination of Fusarium mycotoxins in pig plasma using liquid chromatography tandem mass spectrometry

Siegrid De BaereJoline GoossensVirginie VandenbrouckeAnn OsselaerePatrick De BackerSiska Croubels

Development of in vitro models for a better understanding of the early pathogenesis of Batrachochytrium dendrobatidis infections in amphibians

Pascale Van RooijAn MartelMelanie BrutynSofie MaesKoen ChiersLieven Van WaeyenbergheSiska CroubelsFreddy HaesebrouckFrank Pasmans

A1 Journal Article in ATLA-ALTERNATIVES TO LABORATORY ANIMALS

Flow cytometric differentiation of avian leukocytes and analysis of their intracellular cytokine expression

Sandra De BoeverSiska CroubelsKristel DemeyereBart LambrechtPatrick De BackerEvelyne Meyer

A1 Journal Article in AVIAN PATHOLOGY

Glomerular and tubular markers of renal function in diabetic dogs: comparison to healthy dogs and follow-up

Pascale SmetsEvelyne MeyerBert MaddensSiska CroubelsHervé LefebvreDominique PaepeSylvie Daminet

Immunomodulation, cytokines and antibiotics

Patrick De BackerSiska Croubels

Influencing oral prednisolone absorption in Beagle dogs by modulation of P-glycoprotein expression in the intestinal tract

S Van der HeydenC GadeyneSylvie DaminetSiska CroubelsRichard DucatelleKoen Chiers

Limited sampling strategies to estimate glomerular filtration rate in cats with low, normal and high glomerular filtration rates

Dominique PaepeHervé P LefebvreDidier ConcordetIngrid van HoekPascale SmetsSiska CroubelsSylvie Daminet

Multiplex analysis of pro-inflammatory cytokines and pig-Major Acute Phase Protein in plasma of lipopolysaccharide-challenged pigs

Heidi WynsSiska CroubelsKristel DemeyerePatrick De BackerEvelyne Meyer

Pharmacodynamics of tepoxalin, sodium-salicylate and ketoprofen in an intravenous lipopolysaccharide inflammation model in broiler chickens

Sandra De BoeverEva NeirinckxEvelyne MeyerSiegrid De BaereRudi BeyaertPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Pitfalls in antibiotic residue analysis with emphasis on tetracyclines

Siska CroubelsPatrick De Backer

Quantitative determination of deoxynivalenol and related compounds in animal plasma using LC-MS/MS as part of a toxicokinetic study

Siegrid De BaereAnn OsselaereMathias DevreeseJoline GoossensVirginie VandenbrouckePatrick De BackerSiska Croubels

Species comparison of oral bioavailability, first-pass metabolism and pharmacokinetics of acetaminophen

Eva NeirinckxChris VervaetSandra De BoeverJean Paul RemonKris GommerenSylvie DaminetPatrick De BackerSiska Croubels

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

The influence of modulation of P-glycoprotein and/or Cytochrome P 450 3A on the pharmacokinetics and pharmacodynamics on orally administered morphine in dogs

Caroline GadeyneSara Van der HeydenFrank GasthuysSiska CroubelsStijn SchauvliegeTim WaelbersIngeborgh Polis

The withdrawal time of veterinary drugs and the possible use of a mathematical model to predict residue levels in biological matrices

Els DaeseleireSiska Croubels

Towards a veterinary biopharmaceutics classification system: oral bioavailability and ex vivo intestinal permeability studies of paracetamol and ketoprofen in different animal species

Eva NeirinckxSiska CroubelsChris Vervaet

2009

A pharmacokinetic and pharmacodynamic approach for dosing valacyclovir against equine herpesvirus type 1 infections

Characterization of an intravenous lipopolysaccharide inflammation model in broiler chickens

Sandra De BoeverSiska CroubelsEvelyne MeyerStanislas SysRudi BeyaertRichard DucatellePatrick De Backer

A1 Journal Article in AVIAN PATHOLOGY

Characterization of an intravenous LPS inflammation model in broilers with respect to the pharmacokinetics and pharmacodynamics of nonsteroidal anti-inflammatory drugs

Sandra De BoeverSiska CroubelsPatrick De Backer

Comparative tissue residue depletion and plasma pharmacokinetics of closantel in sheep

Siska CroubelsE FichantAn MaesJL BeaudartPH DelahautPatrick De Backer

Comparison of plasma clearance of exogenous creatinine, exo-iohexol, and endo-iohexol over a range of glomerular filtration rates expected in cats

Ingrid van HoekHervé P LefebvreDominique PaepeSiska CroubelsVincent BiourgeSylvie Daminet

A1 Journal Article in JOURNAL OF FELINE MEDICINE AND SURGERY

Deoxynivalenol (DON) induces increased invasion of Salmonella Typhimurium in alveolar pig macrophages by activation of extracellular regulated kinase (ERK)

Elin VerbruggheVirginie VandenbrouckeSiska CroubelsJoline GoossensPatrick De BackerFilip BoyenFreddy HaesebrouckFrank Pasmans

Determination of acyclovir in horse plasma and body fluids by high-performance liquid chromatography combined with fluorescence detection and heated electrospray ionization tandem mass spectrometry

An MaesBarbara GarréNoël DesmetK van der MeulenHans NauwynckPatrick De BackerSiska Croubels

A1 Journal Article in BIOMEDICAL CHROMATOGRAPHY

Evaluation of orally administered valacyclovir in experimentally EHV1-infected ponies

Barbara GarréAnnick GryspeerdtSiska CroubelsPatrick De BackerHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Influence of administration route on the biotransformation of amoxicillin in the pig

Tim ReynsSiska CroubelsSandra De BoeverStijn SchauvliegeFrank GasthuysGuylaine MeissonnierIsabelle OswaldPatrick De Backer

A1 Journal Article in Journal of veterinary Pharmacology and Therapeutics

Influence of Fusarium toxins on intestinal epithelial cell permeability

Joline GoossensFrank PasmansVirginie VandenbrouckeElin VerbruggheFreddy HaesebrouckPatrick De BackerSiska Croubels

Interspecies comparison of oral bioavailability and jejunal permeability of paracetamol in the framework of a veterinary biopharmaceutics classification system

Eva NeirinckxChris VervaetSandra De BoeverJean Paul RemonPatrick De BackerSiska Croubels

Multiple oral dosing of valacyclovir in horses and ponies

Barbara GarréKris BaertHans NauwynckPiet DeprezPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Mycotoxins in pig feed: influence on the gut and interaction with Salmonella Typhimurium infections

Elin VerbruggheVirginie VandenbrouckeFrank PasmansJoline GoossensFreddy HaesebrouckPatrick De BackerSiska Croubels

Pharmacodynamic properties of salicylate, tepoxalin and ketoprofen in an intravenous LPS inflammation model in broiler chickens

Sandra De BoeverEva NeirinckxRudi BeyaertPatrick De BackerSiska Croubels

Pharmacokinetic and pharmacodynamic properties of orally administered valacyclovir in an equine herpesvirus type 1 infection experiment

Siska CroubelsBarbara GarréAnnick GryspeerdtHans NauwynckPatrick De Backer

Pharmacokinetics of tepoxalin and its active metabolite in broiler chickens

Sandra De BoeverEva NeirinckxKris BaertPatrick De BackerSiska Croubels

A1 Journal Article in Journal of veterinary Pharmacology and Therapeutics

Reduced expression of intestinal P-glycoprotein following ingestion of deoxynivalenol (DON) contaminated feed in pigs

Sara Van der HeydenJoline GoossensVirginie VandenbrouckeGriet VercauterenKoen ChiersFrank PasmansFreddy HaesebrouckPatrick De BackerSiska CroubelsRichard Ducatelle

Reduced expression of intestinal P-glycoprotein following ingestion of deoxynivalenol (DON) contaminated feed in pigs

Joline GoossensVirginie VandenbrouckeSara Van der HeydenRichard DucatelleFrank PasmansFreddy HaesebrouckPatrick De BackerSiska Croubels

Reduced expression of intestinal P-glycoprotein following ingestion of deoxynivalenol (DON) contaminated feed in pigs

Sara Van der HeydenJoline GoossensVirginie VandenbrouckeGriet VercauterenKoen ChiersFrank PasmansFreddy HaesebrouckPatrick De BackerSiska CroubelsRichard Ducatelle

Residue analysis: future trends from a historical perspective

Hubert De BrabanderHerlinde NoppeKarolien VerheydenJulie Vanden BusscheKlaas WilleGodelieve OkermanLynn VanhaeckeWim ReybroeckSigrid OogheSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Short- and long-term follow-up of glomerular and tubular renal markers of kidney function in hyperthyroid cats after treatment with radioiodine

Ingrid van HoekHP LefebvreKathelijne PeremansEvelyne MeyerSiska CroubelsEva VandermeulenHans KooistraJimmy SaundersDominique BinstSylvie Daminet

A1 Journal Article in DOMESTIC ANIMAL ENDOCRINOLOGY

The mycotoxin deoxynivalenol promotes uptake of Salmonella Typhimurium in porcine macrophages, associated with ERK1/2 induced cytoskeleton reorganization

Virginie VandenbrouckeSiska CroubelsElin VerbruggheFilip BoyenPatrick De BackerRichard DucatelleYvan RychlikFreddy HaesebrouckFrank Pasmans

A1 Journal Article in VETERINARY RESEARCH

Transsplenic portal catheterization combined with a jugular double-lumen catheter for pharmacokinetic and presystemic metabolization studies in pigs

Frank GasthuysSandra De BoeverStijn SchauvliegeTim ReynsTamara LevetPieter CornillieChristophe CasteleynPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Urinary markers and plasma iohexol clearance in healthy dogs and dogs with pituitary-dependent hyperadrenocotricism

Pascale SmetsEvelyne MeyerBert MaddensSiska CroubelsHervé LefebvreSylvie Daminet

2008

Disposition kinetics and residue depletion of amoxicillin and its major metabolites in pigs in relation to co-administration of clavulanic acid

Tim ReynsPatrick De BackerSiska Croubels

Glomerular and tubular urinary markers and glomerular filtration ratio in clinically healthy young and aged dogs

Pascale SmetsEvelyne MeyerBert MaddensSiska CroubelsHervé LefebvreSylvie Daminet

Identification and validation of housekeeping genes as internal control for gene expression in an intravenous LPS inflammation model in chickens

Sandra De BoeverC VANGESTELPatrick De BackerSiska CroubelsStanislas Sys

A1 Journal Article in VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Influence of administration route on the biotransformation of amoxicillin in the pig

Tim ReynsSiska CroubelsSandra De BoeverStijn SchauvliegeFrank GasthuysPatrick De Backer

Influence of systemic fluoroquinolone administration on the presence of Pasteurella multocida in the upper respiratory tract of clinically healthy calves

B CATRYSiska CroubelsS SCHWARZPiet DeprezB COXC KEHRENBERGGeert OpsomerAnnemie DecostereFreddy Haesebrouck

A1 Journal Article in ACTA VETERINARIA SCANDINAVICA

Long-term follow-up of glomerular and tubular kidney function in hyperthyroid cats after treatment with radioiodine

Ingrid van HoekHP LefebvreKathelijne PeremansEvelyne MeyerSiska CroubelsEva VandermeulenH KooistraJimmy SaundersDominique BinstSylvie Daminet

Multi-residue analysis of eight anticoagulant rodenticides in animal plasma and liver using liquid chromatography combined with heated electrospray ionization tandem mass spectrometry

Virginie VandenbrouckeNoël DesmetPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pharmacokinetics and clinical efficacy of acyclovir in the treatment of equine herpes virus type 1 infections

Barbara GarréSiska CroubelsHans Nauwynck

Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration

Virginie VandenbrouckeA BOUSQUET-MELOUPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Plasma clearance of exogenous creatinine, exo-iohexol, and endo-iohexol in hyperthyroid cats before and after treatment with radioiodine

Ingrid van HoekHP LefebvreHS KooistraSiska CroubelsDominique BinstKathelijne PeremansSylvie Daminet

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

Plasma clearance of exogenous creatinine, exo-iohexol, and endPlasma clearance of exogenous creatinine, exo-iohexol and endo-iohexol in healthy cats, cats with hyperthyroidism and cats with chronic kidney disease

Ingrid van HoekHP LefebvreSiska CroubelsSylvie Daminet

Rapid method for the quantification of amoxicillin and its major metabolites in pig tissues by liquid chromatography-tandem mass spectrometry with emphasis on stability issues

Tim ReynsMarc CherletSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The influence of age and repeated lipopolysaccharide administration on body temperature and the concentration of interleukin-6 and IgM antibodies against lipopolysaccharide in broiler chickens

Sandra De BoeverRudi BeyaertF VANDEMAELEKris BaertLuc DuchateauBruno GoddeerisPatrick De BackerSiska Croubels

A1 Journal Article in AVIAN PATHOLOGY

Tissue depletion of amoxicillin and its major metabolites in pigs: Influence of the administration route and the simultaneous dosage of clavulanic acid

Tim ReynsSandra De BoeverSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transvenous electrical cardioversion of atrial fibrillation in six horses using custom made cardioversion catheters

Dominique De ClercqGunther van LoonStijn SchauvliegeRené TavernierKris BaertSiska CroubelsPatrick De BackerPiet Deprez

A1 Journal Article in VETERINARY JOURNAL

2007

Comparison and reproducibility of plasma clearance of exogenous creatinine, exo-iohexol, endo-iohexol, and 51Cr-EDTA in young adult and aged healthy cats

Ingrid van HoekEva VandermeulenLuc DuchateauHP LefebvreSiska CroubelsKathelijne PeremansIngeborgh PolisSylvie Daminet

A1 Journal Article in JOURNAL OF VETERINARY INTERNAL MEDICINE

Determination of cefquinome in pig plasma and bronchoalveolar lavage fluid by high-performance liquid chromatography combined with electrospray ionization mass spectrometry

An MaesTom MeynsBart SustronckDominiek MaesPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF MASS SPECTROMETRY

Determination of lidocaine and its two N-desethylated metabolites in dog and horse plasma by high-performance liquid chromatography combined with electrospray ionization tandem mass spectrometry

An MaesLinda WeilandC SANDERSENFrank GasthuysPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Determination of some anticoagulant rodenticides in domestic animals using LC-ESI-MS/MS.

Virginie VandenbrouckeNoël DesmetPatrick De BackerSiska Croubels

Disposition and oral bioavailability of amoxicillin and clavulanic acid in pigs

Tim ReynsSandra De BoeverKris BaertSiska CroubelsStijn SchauvliegeFrank GasthuysPatrick De Backer

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Effect of deoxynivalenol (DON) on growth and virulence gene expression of Salmonella Typhimurium: preliminary results

Virginie VandenbrouckeSiska CroubelsPatrick De BackerFreddy HaesebrouckFrank Pasmans

Effects of an adapted intravenous amiodarone treatment protocol in horses with atrial fibrillation

Dominique De ClercqGunther van LoonKris BaertRené TavernierSiska CroubelsPatrick De BackerPiet Deprez

A1 Journal Article in EQUINE VETERINARY JOURNAL

In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet

Barbara GarréK VAN DER MEULENJ NUGENTJ NEYTSSiska CroubelsPatrick De BackerHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Influence of two different ventilation modes on the function of an anaesthetic conserving device (AnaConDa®) in sevoflurane anaesthetized pigs

Stijn SchauvliegeLindsey DevisscherTim ReynsSandra De BoeverSiska CroubelsFrank Gasthuys

Long term effects of radioiodine treatment on glomerular filtration rate and urinary retinol binding protein in hyperthyroid cats

Ingrid van HoekEva VandermeulenH KOOISTRAH LEFEBVREEvelyne MeyerSiska CroubelsKathelijne PeremansJimmy SaundersSylvie Daminet

Pharmacokinetics of acyclovir after intravenous infusion of acyclovir and after oral administration of acyclovir and its prodrug valacyclovir in healthy adult horses

Barbara GarréKhaled ShebanyAnnick GryspeerdtKris BaertK VAN DER MEULENHans NauwynckPiet DeprezPatrick De BackerSiska Croubels

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plasma clearance of exogenous creatinine, exo-iohexol and endo-iohexol in hyperthyroid cats before and after treatment with radioiodine

Ingrid van HoekHP LefebvreH KooistraSiska CroubelsDominique BinstKathelijne PeremansSylvie Daminet

Quantitative analysis of clavulanic acid in porcine tissues by liquid chromatography combined with electrospray ionization tandem mass spectrometry

Tim ReynsSandra De BoeverSiegrid De BaerePatrick De BackerSiska Croubels

A1 Journal Article in ANALYTICA CHIMICA ACTA

Quantitative determination of acyclovir in horse plasma and white blood cells using LC-ESI-MS/MS as part of a pharmacokinetic study

Barbara GarréNoël DesmetPatrick De BackerK Van der MeulenHans NauwynckSiska Croubels

2006

Charaterisation of an LPS inflammation model in chickens

Sandra De BoeverRudi BeyaertF VANDEMAELEBruno GoddeerisPatrick De BackerSiska Croubels

Control of the keto-enol tautomerism of chlortetracycline for its straightforward quantitation in pig tissues by liquid chromatography-electrospray ionization tandem mass spectrometry

Marc CherletPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Determination of amiodarone and desethylamiodarone in horse plasma and urine by high-performance liquid chromatography combined with UV detection and electrospray ionization mass spectrometry

An MaesKris BaertSiska CroubelsDominique De ClercqGunther van LoonPiet DeprezPatrick De Backer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Determination of cefquinome concentrations in bronchoalveolar lavage fluid

Siska CroubelsTom MeynsA VERHEYENBart SustronckDominiek Maes

Determination of cefquinome concentrations in bronchoalveolar lavage fluid

Tom MeynsSiska CroubelsA VERHEYENBart SustronckDominiek Maes

Determination of clavulanic acid in calf plasma by liquid chromatography tandem mass spectrometry

Tim ReynsSiegrid De BaereSiska CroubelsPatrick De Backer

A1 Journal Article in JOURNAL OF MASS SPECTROMETRY

Determination of major metabolites of amoxicillin in animal urine by LC-MS/MS: biotransformation studies in pigs

Tim ReynsSiegrid De BaereSiska CroubelsPatrick De Backer

Effect of enrofloxacin administration on the occurence of P. multocida in the bovine nasopharynx

Bart CatrySiska CroubelsS SchwarzPiet DeprezC KehrenbergGeert OpsomerAnnemie DecostereFreddy Haesebrouck

Effect of enrofloxacin administration on the occurrence of P. Multocida in the bovine nasopharynx

B CATRYSiska CroubelsS SCHWARZPiet DeprezC KEHRENBERGGeert OpsomerPatrick De BackerA DE COSTEREFreddy Haesebrouck

Evaluation of the pharmacokinetics and bioavailability of intravenously and orally administered amiodarone in horses

Dominique De ClercqKris BaertSiska CroubelsGunther van LoonAn MaesRené TavernierPiet DeprezPatrick De Backer

A1 Journal Article in AMERICAN JOURNAL OF VETERINARY RESEARCH

In vitro comparison of antiviral drugs against feline herpesvirus 1

K VAN DER MEULENBarbara GarréSiska CroubelsHans Nauwynck

In vitro comparison of antiviral drugs against feline herpesvirus 1

Karen van der MeulenBarbara GarréSiska CroubelsHans Nauwynck

A2 Journal Article in BMC VETERINARY RESEARCH

In vitro potency of selected antiviral compounds against six isolates of equine herpesvirus-1 and pharmacokinetics of acyclovir in horses

Barbara GarréK VAN DER MEULENPatrick De BackerHans NauwynckSiska Croubels

Influence of administration route and simultaneous dosage of clavulanic acid on the biotransformation of amoxicillin in pigs

Tim ReynsSandra De BoeverSiegrid De BaereSiska CroubelsPatrick De Backer

Intravenous amiodarone treatment in horses with chronic atrial fibrillation

Dominique De ClercqGunther van LoonKris BaertRené TavernierSiska CroubelsPatrick De BackerPiet Deprez

A1 Journal Article in VETERINARY JOURNAL

Keto-enol tautomerism of chlortetracycline: a hampering factor for quantification in biological matrices ?

Marc CherletSiska CroubelsPatrick De Backer

Persecution of predators in Flanders, January 2003 to March 2006

Paul TavernierSiska CroubelsWilly LambertFrank PasmansKatleen Hermans

Pharmacokinetics and oral bioavailability of florfenicol in veal calves

Siska CroubelsKris BaertTinne VerheyenG BOONEPatrick De Backer

Pharmacokinetics of a lidocaine patch 5% in dogs

Linda WeilandSiska CroubelsKris BaertIngeborgh PolisPatrick De BackerFrank Gasthuys

A1 Journal Article in JOURNAL OF VETERINARY MEDICINE SERIES A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE

Pharmacokinetics of cefquinome in plasma, bronchoalveolar and tracheal lavage fluid of pigs

Siska CroubelsTim ReynsA VERHEYENBart SustronckPatrick De BackerDominiek Maes

Plasma exogenous creatinine clearance test compared to other methods in healthy young adult and elderly cats

Ingrid van HoekEva VandermeulenLuc DuchateauHP LefebvreSiska CroubelsKathelijne PeremansSylvie Daminet

Quantitative determination of chlortetracycline content in animal plasma at controlled keto-enol tautomerism by liquid chromatography-electrospray ionization-tandem mass spectrometry

Marc CherletSiska CroubelsPatrick De Backer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Quantitative determination of clavulanic acid in animal plasma using LC-MS/MS as a part of a pharmacokinetic study in pigs

Tim ReynsSandra De BoeverSiegrid De BaereSiska CroubelsPatrick De Backer

Results of a pharmacokinetic-based intravenous amiodarone treatment in horses with chronic atrial fibrillation

Dominique De ClercqGunther van LoonKris BaertSiska CroubelsR TAVERNIERPatrick De BackerPiet Deprez

Side effects of an intravenous amiodarone infusion protocol in horses

Kris BaertDominique De ClercqSiska CroubelsGunther van LoonPiet DeprezPatrick De Backer

2005

Antivirale behandeling van rinotracheitisvirus, immunodeficientievirus en leukemievirus infecties bij de kat

Eva NeirinckxBarbara GarréHans NauwynckSiska CroubelsPatrick De BackerKaren van der Meulen

A3 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Effect of enrofloxacin on the presence of Pasteurella multocida in the bovine nasopharynx

Boudewijn CatryS SchwarzPiet DeprezC KehrenbergSiska CroubelsGeert OpsomerFreddy Haesebrouck

Equine herpesvirus-1 as a target for antiviral chemotherapy

Barbara GarréKaren van der MeulenSiska CroubelsPatrick De BackerHans Nauwynck

Pharmacokinetics and oral bioavailability of pentoxyfylline in broiler chickens

Sandra De BoeverKris BaertPatrick De BackerSiska Croubels

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Pharmocokinetics of a 5% lidocaine patch in dogs

Linda WeilandSiska CroubelsKris BaertIngeborgh PolisPatrick De BackerFrank Gasthuys

Quantitative determination of dexamethasone in bovine plasma and tissues by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry to monitor residue depletion kinetics

Marc CherletSiegrid De BaereSiska CroubelsPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Quantitative determination of salicylic acid and metabolites in animal tissues by liquid chromatography-tandem mass spectrometry

Siska CroubelsAn MaesKris BaertPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Quantitative liquid chromatographic-mass spectrometric analysis of amoxycillin in broiler edible tissues

Siegrid De BaerePasquale WassinkSiska CroubelsSandra De BoeverKris BaertPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Synovial fluid and plasma concentrations of ceftiofur after regional intravenous perfusion in the horse

Frederik PilleSiegrid De BaereLiesbeth CeelenJeroen DewulfSiska CroubelsFrank GasthuysPatrick De BackerAnn Martens

A1 Journal Article in VETERINARY SURGERY

Two unusual cases of plant intoxication in small ruminants

Kris BaertSiska CroubelsNathalie SteurbautSandra De BoeverGriet VercauterenRichard DucatelleAnnemieke VerbekenPatrick De Backer

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

2004

Amiodarone treatment for chronic atrial fibrillation in horse : preliminary results

Dominique De ClercqGunther van LoonKris BaertRené TavernierSiska CroubelsPatrick De BackerPiet Deprez

Comparative metabolic excretion profile of sodium salicylate in broiler chickens and homing pigeons

Kris BaertSiska CroubelsA MAESUlrik HillaertSerge Van CalenberghPatrick De Backer

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Evaluation and establishing the performance of different screening tests for tetracycline residues in animal tissues

Godelieve OkermanSiska CroubelsMarc CherletK DE WASCHPatrick De BackerJan Van Hoof

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS

Evaluation and validation of different screening tests for tetracycline resiudes in animal tissues

Godelieve OkermanSiska CroubelsMarc CherletK DE WASCHPatrick De BackerJan Van Hoof

Evaluation and validation of different screenings tests for tetracyclines residues in animal tissues

Godelieve OkermanSiska CroubelsM CHERLETK DE WASHP DE BACKERJan Van Hoof

High-performance liquid chromatographic-UV detection analysis of ceftiofur and its active metabolite desfuroylceftiofur in horse plasma and synovial fluid after regional intravenous perfusion and systemic intravenous injection of ceftiofur sodium

S DE BAEREFrederik PilleSiska CroubelsLiesbeth CeelenPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Lingual and pharyngeal paralysis due to acute doxycycline intoxication in veal calves

Koen ChiersP WEYENSPiet DeprezMarjolein van HeerdenGodelieve MeulemansKris BaertSiska CroubelsPatrick De BackerRichard Ducatelle

A1 Journal Article in VETERINARY RECORD

MRL en wachttijd

A4 Journal Article in VEVA

Quantitative analysis of dexamethasone in bovine tissues by LC-APCI-MS/MS: residue depletion kinetics after intravenous administration

Marc CherletSiegrid De BaereSiska CroubelsPatrick De Backer

Quantitative determination of salicylate and metabolites in animal tissues by LC-MS/MS

Siska CroubelsAn MaesKris BaertPatrick De Backer

Residues in Meat and Meat Products, Feed and drug residues

Siska CroubelsEls DaeseleireSiegrid De BaerePatrick De BackerDirk Courtheyn

Bookchapter in Encyclopedia of Meat Sciences

2003

2,5-bis-(2-hydroxybenzoylamino)pentanoic acid, a salicylic acid-metabolite isolated from chicken: Characterization and independent synthesis

Ulrik HillaertKris BaertJ ROZENSKISiska CroubelsDenis De KeukeleirePatrick De BackerSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comparison of a liquid chromatographic method with ultraviolet and ion-trap tandem mass spectrometric detection for the simultaneous determination of sulfadiazine and trimethoprim in plasma from dogs

Siska CroubelsS DE BAEREPatrick De Backer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Influence of acetylsalicylic acid and ketoprofen on canine thyroid function tests

Sylvie DaminetSiska CroubelsLuc DuchateauAnn DebunneCindy Van GeffenYves HoybergsHenri van BreeAndré De Rick

A1 Journal Article in VETERINARY JOURNAL

Lingual and pharyngeal paralysis in acute doxycyclin intoxication in veal calves

Koen ChiersP WEYENSPiet DeprezMarjolein van HeerdenGodelieve MeulemansKris BaertSiska CroubelsPatrick De BackerRichard Ducatelle

Liquid chromatographic determination of levamisole in animal plasma: ultraviolet versus tandem mass spectrometric detection

S DE BAEREM CHERLETSiska CroubelsKris BaertPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Pharmacokinetics and biotransformation of salicylate in broiler chickens and homing pigeons

Siska CroubelsKris BaertAn MaesPatrick De Backer

Pharmacokinetics and oral bioavailability of sulfadiazine and trimethoprim in broiler chickens

Kris BaertS DE BAERESiska CroubelsPatrick De Backer

A1 Journal Article in VETERINARY RESEARCH COMMUNICATIONS

Practical approach for the stability testing of veterinary drugs in solutions and in biological matrices during storage

Siska CroubelsS DE BAEREPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Quantitative determination of desfuroylceftiofur in horse plasma and synovial fluid after regional intravenous perfusion and intra-articular injection of ceftiofur

Siegrid De BaereFrederik PilleSiska CroubelsLiesbeth CeelenPatrick De Backer

Quantitative multi-residue analysis of tetracyclines and their 4-epimers in pig tissues by high-performance liquid chromatography combined with positive-ion electrospray ionization mass spectrometry

M CHERLETMario SchelkensSiska CroubelsPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

The pharmacokinetic profile of amoxicillin and its major metabolites in porcine urine and plasma

L VAN GILSSiska CroubelsSiegrid De BaerePatrick De Backer

Tiamuline-salinomycine intoxicatie door drinkwaterresiduen

A4 Journal Article in VEVA

2002

Determination of clindamycin in animal plasma by high-performance liquid chromatography combined with electrospray ionization mass spectrometry.

M CHERLETSiska CroubelsPatrick De Backer

A1 Journal Article in JOURNAL OF MASS SPECTROMETRY

Determination of ivermectin B-1a in animal plasma by liquid chromatography combined with electrospray ionization mass spectrometry.

Siska CroubelsS DE BAEREM CHERLETPatrick De Backer

A1 Journal Article in JOURNAL OF MASS SPECTROMETRY

Quantitation of tylosin in swine tissues by liquid chromatography combined with electrospray ionization mass spectrometry.

M CHERLETS DE BAERESiska CroubelsPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

Quantitative analysis of diclazuril in animal plasma by liquid chromatography/electrospray ionization mass spectrometry.

Siska CroubelsM CHERLETPatrick De Backer

A1 Journal Article in RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Simultaneous determination of sulfadiazine and trimethoprim in animal feed by liquid chromatography with UV and tandem mass spectrometric detection.

Siska CroubelsP WASSINKPatrick De Backer

A1 Journal Article in ANALYTICA CHIMICA ACTA

2001

A special case of an acute tiamulin-salinomycin intoxication in pigs due to residual tiamulin four months after medication.

Siska CroubelsJ VRIELINCKKris BaertI VERMAUTFrans CastryckPatrick De Backer

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Chronic copper intoxication in veal calves.

Siska CroubelsKris BaertT TORCKPiet DeprezPatrick De Backer

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Inhibition tests for detection and presumptive identification of tetracyclines, beta-lactam antibiotics and quinolones in poultry meat.

Godelieve OkermanSiska CroubelsS DE BAEREJan Van HoofPatrick De BackerHubert De Brabander

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS

Pharmacokinetics and bioavailability of sulfadiazine and trimethoprim (trimazin 30%) after oral administration in non-fasted young pigs.

Kris BaertS DE BAERESiska CroubelsFrank GasthuysPatrick De Backer

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

2000

Analytical Potentials of Luminescence - Based Techniques in Flowing Streams.

W BAEYENSAM GARCIA CAMPANASiska CroubelsAC CALOKERINOS

Determination and quantification of sulfadiazine and trimethoprim in swine tissues using liquid chromatography with ultraviolet and mass spectrometric detection.

S DE BAEREKris BaertSiska CroubelsJ DE BUSSERK DE WASCHPatrick De Backer

A1 Journal Article in ANALYST

Pharmacokinetics and oral bioavailability of a doxycycline formulation (DOXYCYCLINE 75%) in nonfasted young pigs.

Kris BaertSiska CroubelsFrank GasthuysJ DE BUSSERPatrick De Backer

A1 Journal Article in JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Quantitative analysis of gentamicin in animal tissues by ion-pair reversed phase high-performance liquid chromatography combined with electrospray ionisation mass spectrometry.

M CHERLETS DE BAERESiska CroubelsPatrick De Backer

Quantitative analysis of levamisole in porcine tissues by high-performance liquid chromatography combined with atmospheric pressure chemical ionization mass spectrometry.

M CHERLETS DE BAERESiska CroubelsPatrick De Backer

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B

1999

The detection of residues of doxycycline in porcine kidney and muscle tissue: Correlation between results of microbiological screening and confirmation tests.

Siska CroubelsKris BaertGodelieve OkermanV ROBBRECHTL AERDENPatrick De Backer

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

1998

Detection of residues of tetracycline antibiotics in pork and chicken meat: Correlation between results of screening and confirmatory tests.

Katia De WaschGodelieve OkermanSiska CroubelsHubert De BrabanderJan Van HoofPatrick De Backer

A1 Journal Article in ANALYST

Liquid chromatographic separation of doxycycline and 4-epidoxycycline in a tissue depletion study of doxycycline in turkeys.

Siska CroubelsHubert VermeerschPatrick De BackerMDF SANTOSJean Paul RemonCarlos Van Peteghem

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B

Residue study of doxycycline and 4-epidoxycycline in pigs medicated via drinking water.

Siska CroubelsKris BaertJ DE BUSSERPatrick De Backer

A1 Journal Article in ANALYST

1997

Considerations on the potentials of miniaturised liquid chromatography versus capillary electrophoresis in pharmaceutical analysis.

Willy BaeyensAn Van OverbekeG VANDERWEKENSiska CroubelsKE GARCIA

A1 Journal Article in QUIMICA ANALITICA

Residue Study of Doxycycline in Turkeys medicated via Drinking Water under Field Conditions

Siska CroubelsH VERMEERSCHMDF SANTOSP DE BACKERJP REMONCarlos Van Peteghem

A2 Journal Article in Journal of Veterinary Pharmacology and Therapy, 20 (Suppl.l), p. 194, 1 fig

Use of metal chelate affinity chromatography and membrane-based ion-exchange as clean-up procedure for trace residue analysis of tetracyclines in animal tissues and egg

Siska CroubelsKristina VanoosthuyzeCarlos Van Peteghem

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B

Vlaamse doctoraten

Editorial material

1996

Analytische strategie voor de detectie van residuen van tetracycline en verwante produkten in nieren en vlees

Siska CroubelsGodelieve OkermanKristina VanoosthuyzeJ VAN HOOFCarlos Van Peteghem

Methodologie voor de bepaling van residuen van enkele tetracyclines in voedingsmiddelen van dierlijke oorsprong

Siska CroubelsC. Van Peteghem

1995

Capillary electrophoresis versus miniaturised liquid chromatography in pharmaceutical analysis

Willy BaeyensPatrick SandraAn Van OverbekeGuido Van der WekenSiska Croubels

Evaluation of a narrow-bore HPLC column for trace level analysis of tetracyclines : a comparison with a conventional column

Siska CroubelsWilly BaeyensCarlos Van Peteghem

A1 Journal Article in BIOMEDICAL CHROMATOGRAPHY

Postcolumn zirconium chelation and fluorescence detection for the liquid-chromatographic determination of tetracyclines

Siska CroubelsWilly BaeyensCarlos Van Peteghem

A1 Journal Article in ANALYTICA CHIMICA ACTA

Residues of tetracyclines in milk : evaluation of a commercial enzyme immunological screening test by high-performance liquid chromatography

Siska CroubelsCarlos Van Peteghem

1994

Capillary Electrophoresis of Some Tetracycline Antibiotics.

Siska CroubelsWilly BaeyensC DEWAELECarlos Van Peteghem

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY A

Sensitive spectrofluorimetric determination of tetracycline residues in bovine milk

Siska CroubelsCarlos Van PeteghemWilly Baeyens

A1 Journal Article in ANALYST

Comparison of different withdrawal time calculation approaches for chlortetracycline in milk

Siska CroubelsS DE BAEREPatrick De Backer

Confirmation of tetracycline residues by HPLC after microbiological and ELIS A screening of kidney and meat tissue. Euroresidue III Proceedings, 1996, pp. 362-366.

Siska CroubelsGodelieve OkermanKristina VanoosthuyzeJ VAN HOOFCarlos Van Peteghem

Discrepancy in the concentration of amoxycillin in faeces of pigeons and tissues of pigs after analysis by different HPLC methods

S DE BAERESiska CroubelsKris BaertPatrick De Backer

N. Haagsma and A. Ruiter (Eds.), Residues of Veterinary Drugs in Food, ISBN: 906159023X. Proceedings of the Euroresidue III Conference, Veldhoven (NL), 6-8 mei 1996, pp. 362-366, 1 fig., 1 tab.

Siska CroubelsGodelieve OkermanKristina VanoosthuyzeJ VAN HOOFCarlos Van Peteghem

Residue depletion of sulfadiazine and trimethoprim in chickens after oral administration via the drinking water

S DE BAERESiska CroubelsKris BaertPatrick De Backer

The proposed MRL for doxycycline: controversy about the inclusion of the 4-epimer as marker

Siska CroubelsS DE BAEREPatrick De Backer