Research Explorer

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Researcher

Simon Verdonck

Publications & Research Data

Awards & Distinctions

5 Results

2025

ATG9A-mediated autophagy prevents inflammatory skin disease by limiting TNFR1-driven STING activation and ZBP1-dependent cell death

Dario PriemJon HuygheBarbara GilbertSimon VerdonckTom DelangheBruno VerstraetenEsther HostePeter VandenabeeleJonathan MaelfaitGeert van Loo et al.

A1 Journal Article in IMMUNITY

Regulation of interferon-mediated autoinflammation by RIPK1 and ADAR1

Simon VerdonckJonathan MaelfaitPeter Vandenabeele

2022

ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation

Richard de ReuverSimon VerdonckEvelien DierickJosephine NemegeerEline HessmannSadeem AhmadMaude JansGillian BlanckeFilip Van NieuwerburghAlexander Botzki et al.

A1 Journal Article in NATURE

Viral manipulation of host cell necroptosis and pyroptosis

Simon VerdonckJosephine NemegeerPeter VandenabeeleJonathan Maelfait

A1 Journal Article in TRENDS IN MICROBIOLOGY

Viral RHIM proteins antagonise necroptosis by preventing ZBP1-induced RIPK1/RIPK3 amyloid formation in human cells

Josephine NemegeerLeslie NaesensSimon VerdonckEvelien DierickKatrien StaesPeter VandenabeeleJonathan Maelfait