Research Explorer

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Researcher

Sielke Caestecker

Awards & Distinctions

7 Results

2025

Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses

Sielke CaesteckerEmma LescrauwaetKristl VonckMathieu SprengersEvelien CarrettePaul BoonLars Emil LarsenRobrecht Raedt

A1 Journal Article in FRONTIERS IN NEUROSCIENCE

Embedded system for responsive optogenetic control of spontaneous seizures in a preclinical temporal lobe epilepsy model

Sofie LasureLien De SchaepmeesterSielke CaesteckerJeroen SpanogheMarijke VergaelenRik VerplanckeJohannes VierockRobrecht RaedtPieter Bauwens

2024

Chemogenetic activation of the locus coeruleus increases hippocampal noradrenaline levels leading to modulation of hippocampal excitability

Sielke CaesteckerLars Emil LarsenPaul BoonKristl VonckRobrecht Raedt

2023

Chemogenetic activation of the locus coeruleus increases noradrenaline levels and modulates hippocampal excitability

Sielke CaesteckerRobrecht RaedtPaul BoonKristl VonckLars Emil Larsen

Chemogenetic activation of the locus coeruleus increases noradrenaline levels in the hippocampus and modulates its hippocampal excitability

Sielke CaesteckerRobrecht RaedtPaul BoonKristl VonckLars Emil Larsen

Hippocampal seizures differentially modulate locus coeruleus activity and result in consistent time-locked release of noradrenaline in rat hippocampus

Lars Emil LarsenSielke CaesteckerLatoya StevensPieter van MierloEvelien CarrettePaul BoonKristl VonckRobrecht Raedt

A1 Journal Article in NEUROBIOLOGY OF DISEASE

2022

Hippocampal seizures strongly modulate the activity of locus coeruleus neurons

Sielke CaesteckerRobrecht RaedtPaul BoonKristl VonckLars Emil Larsen