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Researcher
Sebastian Leimbacher
Profile
Projects
Publications
Activities
Awards & Distinctions
19
Results
2025
Assessing the effect of aberrant FOXG1 expression in neural organoids
Nore Van Loon
Lukas Genbrugge
Emiel Van Wetter
Fynn Maximilian Godefroy
Michael B Vaughan
Lisa Hamerlinck
Lara Colombo
Sebastian Leimbacher
Lies Vantomme
Esperanza Daal
et al.
U
Conference
2025
Assessing the effect of aberrant FOXG1 expression in neural organoids
Nore Van Loon
Lukas Genbrugge
Emiel Van Wetter
Fynn Maximilian Godefroy
Michael B Vaughan
Lisa Hamerlinck
Lara Colombo
Sebastian Leimbacher
Lies Vantomme
Esperanza Daal
et al.
U
Conference
2025
Loss of function of the zinc finger homeobox 4 gene, ZFHX4, underlies a neurodevelopmental disorder
Maria del Rocio Pérez Baca
María Palomares-Bralo
Michiel Vanhooydonck
Lisa Hamerlinck
Eva D'haene
Sebastian Leimbacher
Eva Jacobs
Laurenz De Cock
Erika D'haenens
Annelies Dheedene
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF HUMAN GENETICS
2025
Non-coding structural variants disrupt a critical regulatory region steering FOXG1 transcription during early neurodevelopment
Eva D'haene
Lisa Hamerlinck
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Sebastian Leimbacher
Lara Colombo
Lies Vantomme
Esperanza Daal
Annelies Dheedene
et al.
U
Conference
2025
Non-coding structural variants disrupt regulatory elements steering FOXG1 transcription in early neurodevelopment
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Lara Colombo
Sebastian Leimbacher
Esperanza Daal
Lies Vantomme
Annelies Dheedene
et al.
U
Conference
2025
Non-coding structural variants identify a commonly affected regulatory region steering FOXG1 transcription in early neurodevelopment
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Lara Colombo
Sebastian Leimbacher
Esperanza Daal
Lies Vantomme
Annelies Dheedene
et al.
U
Conference
2025
Non-coding structural variants identify a commonly affected regulatory region steering FOXG1 transcription in early neurodevelopment
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Sebastian Leimbacher
Lara Colombo
Lies Vantomme
Esperanza Daal
Annelies Dheedene
et al.
Preprint
2025
Non-coding structural variants identify a commonly affected regulatory region steering FOXG1 transcription in early neurodevelopment
Eva D'haene
Lisa Hamerlinck
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Sebastian Leimbacher
Lara Colombo
Lies Vantomme
Esperanza Daal
Annelies Dheedene
et al.
U
Conference
2025
SYSTEMATIC COMPARATIVE ANALYSIS OF 3D GENOME STRUCTURE BETWEEN NEURONAL AND CLINICALLY ACCESSIBLE TISSUES HIGHLIGHTS TISSUE-SPECIFIC CHROMATIN FEATURES AT DISEASE LOCI
Lara Colombo
Michael B Vaughan
Nore Van Loon
Sebastian Leimbacher
Esperanza Daal
Eva D'haene
Sarah Vergult
U
Conference
2025
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Lara Colombo
Sebastian Leimbacher
Esperanza Daal
Lies Vantomme
Annelies Dheedene
et al.
U
Conference
2025
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Michael B Vaughan
Lara Colombo
Maria del Rocio Pérez Baca
Sebastian Leimbacher
Esperanza Daal
Lies Vantomme
Annelies Dheedene
et al.
U
Conference
2025
Tissue-Specific 3D Genome and Splicing Signatures of Clinically Accessible Tissues Inform Sample Selection for Assessing the impact of Genomic Aberrations in Neurodevelopmental Disorders
Michael B Vaughan
Lara Colombo
Esperanza Daal
Aude Beyens
Eva Vanbelleghem
Robbe Derudder
Sebastian Leimbacher
Eva D'haene
Bert Callewaert
Sarah Vergult
U
Conference
2025
2024
Assessing the effect of aberrant FOXG1 expression in neural organoids
Nore Van Loon
Lukas Genbrugge
Emiel Van Wetter
Fynn Maximilian Godefroy
Michael B Vaughan
Lisa Hamerlinck
Lara Colombo
Sebastian Leimbacher
Lies Vantomme
Esperanza Daal
et al.
U
Conference
2024
Assessing the effect of aberrant FOXG1 expression in neural organoids
Nore Van Loon
Lukas Genbrugge
Emiel Van Wetter
Fynn Maximilian Godefroy
Michael B Vaughan
Lisa Hamerlinck
Lara Colombo
Sebastian Leimbacher
Lies Vantomme
Esperanza Daal
et al.
U
Conference
2024
Comparison of 3D genome structure between neuronal and clinically accessible tissues
Lara Colombo
Michael B Vaughan
Nore Van Loon
Sebastian Leimbacher
Esperanza Daal
Eva D'haene
Sarah Vergult
C3
Conference
2024
Comparison of 3D genome structure between neuronal and clinically accessible tissues
Lara Colombo
Eva D'haene
Michael B Vaughan
Nore Van Loon
Sebastian Leimbacher
Esperanza Daal
Sarah Vergult
U
Conference
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder
Maria del Rocio Pérez Baca
Maria Palomares Bralo
Michiel Vanhooydonck
Lisa Hamerlinck
Eva D'haene
Sebastian Leimbacher
Eva Jacobs
Laurenz De Cock
Erika D'haenens
Zoë Malfait
et al.
C3
Conference
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder
Maria del Rocio Pérez Baca
María Palomares Bralo
Michiel Vanhooydonck
Lisa Hamerlinck
Eva D'haene
Sebastian Leimbacher
Eva Jacobs
Laurenz De Cock
Erika D'haenens
Annelies Dheedene
et al.
Preprint
2024
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Nore Van Loon
Michael B Vaughan
Maria del Rocio Pérez Baca
Lara Colombo
Sebastian Leimbacher
Esperanza Daal
Lies Vantomme
Björn Menten
Bert Callewaert
et al.
U
Conference
2024