Research Explorer

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Researcher

Sebastiaan Theuns

Publications & Research Data

Awards & Distinctions

80 Results

2025

Genomic analysis and replication kinetics of the closely related EHV-1 neuropathogenic 21P40 and abortigenic 97P70 strains

Eslam MohamedInes ZarakNick VereeckeSebastiaan TheunsKathlyn LavalHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Perirenal subcapsular hematomas in feline infectious peritonitis

Laura de JongLuna Vanden BuijsSieglinde CoppensSebastiaan TheunsHans NauwynckKoen ChiersBert De Jonge

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

The canine vaginal microbiome

Lotte SpanogheAnn Van SoomGuillaume DomainPenelope BanchiFlorin PosastiucGowri Amanda HettiarachchiAdelaide PanattoniSebastiaan TheunsFilip Van ImmerseelGeert Opsomer

Toward standardized methods in canine vaginal microbiome research : evaluation of storage, host DNA depletion, and database selection

Lotte SpanogheGuillaume DomainFlorin PosastiucGowri Amanda HettiarachchiAdelaide PanattoniSebastiaan TheunsFilip Van ImmerseelGeert OpsomerAnn Van SoomPenelope Banchi

A1 Journal Article in MICROBIOLOGY SPECTRUM

2024

Characterization of Corynebacterium isolates obtained from brown rats

Filip BoyenKristof BaertGowri Amanda HettiarachchiSofie De BruyckereSarah Van PraetSerge VerbanckSebastiaan TheunsFrank PasmansAn Martel

Cross-correlation between biosecurity measures and the detection of viral and bacterial agents on German farms with respiratory disease

Julia StadlerKathrin Lillie-JaschniskiSophia ZwicklSusanne ZoelsSebastiaan TheunsMathias RitzmannNick Vereecke

A1 Journal Article in TRANSBOUNDARY AND EMERGING DISEASES

New insights into honey bee viral and bacterial seasonal infection patterns using third-generation nanopore sequencing on honey bee haemolymph

Cato Van HerzeleSieglinde CoppensNick VereeckeSebastiaan TheunsDirk de GraafHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

2023

Characterization of third generation cephalosporin resistant Enterobacteriaceae from healthy pigs in western region of Cuba

Yanet López DortaHaylen Oliva BelloFilip BoyenNick VereeckeMichel Baez-AriasSebastiaan TheunsYvette EspinosaEric CoxPedro de la Fé RodriguezPatrick Butaye

European veterinary barometer for bovine respiratory diseases : a comprehensive tool for mapping diagnostic test results and geolocation for respiratory tract samples from cattle

Jade BokmaInge Santman-BerendsGema VidalMiel HostensStefaan RibbensJulien EvrardSebastiaan TheunsCosmé Sánchez-MiguelGerdien van SchaikBart Pardon

European veterinary barometer for Bovine Respiratory Diseases : a tool showing diagnostic test results and geolocation of respiratory tract samples from cattle

Jade BokmaInge Santman-BerendsGema VidalMiel HostensStefaan RibbensJulien EvrardSebastiaan TheunsGerdien van SchaikBart Pardon

Porcine ear necrosis : characterization of lesions and associated pathogens

Mateusz MalikKoen ChiersSebastiaan TheunsNick VereeckeIlias ChantziarasSiska CroubelsDominiek Maes

A1 Journal Article in VETERINARY RESEARCH

Predictive power of long-read whole-genome sequencing for rapid diagnostics of multidrug-resistant brachyspira hyodysenteriae strains

Nick VereeckeNadine BotteldoornCharlotte BrosséCaroline BonckaertHans NauwynckFreddy HaesebrouckFilip BoyenDominiek MaesSebastiaan Theuns

A1 Journal Article in MICROBIOLOGY SPECTRUM

Prevalence and molecular characterization of methicillin-resistant Staphylococci (MRS) and Mammaliicocci (MRM) in dromedary camels from Algeria : first detection of SCCmec-mecC hybrid in methicillin-resistant Mammaliicoccus lentus

Chahrazed BelhoutFilip BoyenNick VereeckeSebastiaan TheunsNadia TaibiMarc SteggerPedro Yoelvys de la Fé-RodríguezLeila BouayadRachid ElgroudPatrick Butaye

A1 Journal Article in ANTIBIOTICS-BASEL

Revolutionizing viral and bacterial diagnostics in veterinary medicine using nanopore sequencing

Nick VereeckeHans NauwynckSebastiaan TheunsFreddy HaesebrouckMarjan De Mey

Surveillance and genomic characterization of Influenza A and D viruses in swine, Belgium and the Netherlands, 2019–2021

Anna ParysNick VereeckeElien VandoornSebastiaan TheunsKristien Van Reeth

A1 Journal Article in EMERGING INFECTIOUS DISEASES

Viral and bacterial profiles in endemic influenza A virus infected swine herds using nanopore metagenomic sequencing on tracheobronchial swabs

Nick VereeckeSophia ZwicklSophie GumbertAnnika GraafTimm HarderMathias RitzmannKathrin Lillie-JaschniskiSebastiaan TheunsJulia Stadler

A1 Journal Article in MICROBIOLOGY SPECTRUM

Virotyping and genetic antimicrobial susceptibility testing of porcine ETEC/STEC strains and associated plasmid types

Nick VereeckeSander Van hoordeDaniel SperlingSebastiaan TheunsBert DevriendtEric Cox

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Whole genome sequencing to study antimicrobial resistance and RTX virulence genes in equine Actinobacillus isolates

Nick VereeckeArlette VandekerckhoveSebastiaan TheunsFreddy HaesebrouckFilip Boyen

A1 Journal Article in VETERINARY RESEARCH

2022

Genomics-based epidemiology and antimicrobial susceptibility of Mycoplasma bovis isolates from veal, dairy, and beef herds

Jade BokmaNick VereeckeLinde GilleLaura Van DriesscheKoen De BleeckerHans NauwynckFreddy HaesebrouckSebastiaan TheunsFilip BoyenBart Pardon

Milk lactose protects against porcine group A rotavirus infection

Xiaolei RenWaqar SaleemRobin HaesJiexiong XieSebastiaan TheunsHans Nauwynck

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Milk lactose protects against porcine group A rotavirus infection

Xiaolei RenWaqar SaleemRobin HaesJiexiong XieSebastiaan TheunsHans Nauwynck

Molecular epidemiology of Porcine Parvovirus Type 1 (PPV1) and the reactivity of vaccine-induced antisera against historical and current PPV1 strains

Nick VereeckeLise Kirstine KvisgaardGuy BaeleCarine BooneMarius KunzeLars Erik LarsenSebastiaan TheunsHans Nauwynck

A1 Journal Article in VIRUS EVOLUTION

The attenuated pseudorabies virus vaccine strain Bartha hyperactivates plasmacytoid dendritic cells by generating large amounts of cell-free virus in infected epithelial cells

Jonas DelvaCliff Van WaesbergheWim Van Den BroeckJochen LamoteNick VereeckeSebastiaan TheunsLiesbeth CouckHerman Favoreel

A1 Journal Article in JOURNAL OF VIROLOGY

Virus discovery in small mammals : a closer look at the families arteriviridae and paramyxoviridae

Bert VanmechelenHans NauwynckPiet MaesSebastiaan Theuns

2021

Evaluation of nanopore sequencing as a diagnostic tool for the rapid identification of Mycoplasma bovis from individual and pooled respiratory tract samples

Jade BokmaNick VereeckeMathilde PasLaurens ChantillonMarianne VahlEefke WeesendorpRuud H. DeurenbergHans NauwynckFreddy HaesebrouckSebastiaan Theuns et al.

A1 Journal Article in JOURNAL OF CLINICAL MICROBIOLOGY

Genome-wide association study reveals genetic markers for antimicrobial resistance in Mycoplasma bovis

Jade BokmaNick VereeckeHans NauwynckFreddy HaesebrouckSebastiaan TheunsBart PardonFilip Boyen

A1 Journal Article in MICROBIOLOGY SPECTRUM

Mycoplasma bovis point mutations as genetic markers for antimicrobial resistance revealed by Genome Wide Association Study (lecture, 12 min.)

Nick VereeckeJade BokmaFreddy HaesebrouckHans NauwynckSebastiaan TheunsBart PardonFilip Boyen

Organ-specific genome diversity of replication-competent SARS-CoV-2

Jolien Van CleemputWillem van SnippenbergLaurens LambrechtsAmélie DendoovenValentino D'OnofrioLiesbeth CouckWim TrypsteenJan VanrusseltSebastiaan TheunsNick Vereecke et al.

A1 Journal Article in NATURE COMMUNICATIONS

Presence of broad-spectrum beta-lactamase-producing Enterobacteriaceae in zoo mammals

Chloë De WitteNick VereeckeSebastiaan TheunsClaudia De RuyckFrancis VercammenTim BoutsFilip BoyenHans NauwynckFreddy Haesebrouck

A1 Journal Article in MICROORGANISMS

2020

A comparative study of techniques used for the diagnosis of effusive feline infectious peritonitis

Arnaut HellemansDelphine AcarVeerle StroobantsSebastiaan TheunsL. M. B. DesmaretsHans Nauwynck

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

High quality genome assemblies of Mycoplasma bovis using a taxon-specific Bonito basecaller for MinION and Flongle long-read nanopore sequencing

Nick VereeckeJade BokmaFreddy HaesebrouckHans NauwynckFilip BoyenBart PardonSebastiaan Theuns

A1 Journal Article in BMC BIOINFORMATICS

High quality MinION and Flongle long-read nanopore genome assemblies of Mycoplasma bovis using taxon-specific training of the Bonito basecaller

Nick VereeckeJade BokmaBart PardonFilip BoyenHans NauwynckSebastiaan Theuns

Phylogenomic analysis and antimicrobial susceptibility data of Mycoplasma bovis from different Belgian cattle production systems

Jade BokmaNick VereeckeKoen De BleeckerJozefien CallensHans NauwynckFreddy HaesebrouckSebastiaan TheunsBart PardonFilip Boyen

Phylogenomic analysis of Mycoplasma bovis from Belgian veal, dairy and beef herds

Jade BokmaNick VereeckeKoen De BleeckerJozefien CallensStefaan RibbensHans NauwynckFreddy HaesebrouckSebastiaan TheunsFilip BoyenBart Pardon

A1 Journal Article in VETERINARY RESEARCH

Role of porcine amino peptidase N and sialic acids in porcine coronavirus infections in primary porcine enterocytes

Tingting CuiSebastiaan TheunsJiexiong XieWim Van Den BroeckHans Nauwynck

A2 Journal Article in VIRUSES

Role of Porcine Aminopeptidase N and Sialic Acids in Porcine Coronavirus Infections in Primary Porcine Enterocytes.

Tingting CuiSebastiaan TheunsJiexiong XieWim Van Den BroeckHans Nauwynck

A1 Journal Article in Viruses

2019

A new co-culture system of primary porcine enterocytes/myofibroblasts to investigate the replication characteristics of porcine enteric viruses in their target cell

Tingting CuiHans NauwynckSebastiaan Theuns

Changes on the viral capsid surface during the evolution of porcine circovirus type 2 (PCV2) from 2009 till 2018 may lead to a better receptor binding

Ruifang WeiJiexiong XieSebastiaan TheunsHans Nauwynck

A1 Journal Article in VIRUS EVOLUTION

Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface

Tingting CuiSebastiaan TheunsJiexiong XieHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

2018

Establishment of porcine enterocyte/myofibroblast co-cultures for the growth of porcine rota- and coronaviruses

Tingting CuiSebastiaan TheunsLowiese DesmaretsJiexiong XieGaëtan De GryseBo YangWim Van Den BroeckHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus

Sebastiaan TheunsBert VanmechelenQuinten BernaertWard DeboutteMarilou VandenholeLeen BellerJelle MatthijnssensPiet MaesHans Nauwynck

A1 Journal Article in SCIENTIFIC REPORTS

2017

Identification of an enterovirus recombinant with a torovirus-like gene insertion during a diarrhea outbreak in fattening pigs

Nádia Conceição-NetoSebastiaan TheunsTingting CuiMark ZellerClaude Kwe YindaIsaura ChristiaensElisabeth HeylenMarc Van RanstSebastien CarpentierHans Nauwynck et al.

A1 Journal Article in VIRUS EVOLUTION

2016

Characterization of a genetically heterogeneous porcine rotavirus C, and other viruses present in the fecal virome of a non-diarrheic Belgian piglet

Sebastiaan TheunsNádia Conceição-NetoMark ZellerElisabeth HeylenInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

A1 Journal Article in INFECTION GENETICS AND EVOLUTION

Differences in Env and Gag protein expression patterns and epitope availability in feline immunodeficiency virus infected PBMC compared to infected and transfected feline model cell lines

Inge RoukaertsChris K GrantSebastiaan TheunsIsaura ChristiaensDelphine AcarSebastiaan Van BockstaelLowiese DesmaretsHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures

Lowiese DesmaretsBen VermeulenSebastiaan TheunsNádia Conceição-NetoMark ZellerInge RoukaertsDelphine AcarDominique OlyslaegersMarc Van RanstJelle Matthijnssens et al.

A1 Journal Article in SCIENTIFIC REPORTS

MCMV exploits the spleen as a transfer hub for systemic dissemination upon oronasal inoculation

Shunchuan ZhangJun XiangSebastiaan TheunsLowiese DesmaretsHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Presence and characterization of pig group A and C rotaviruses in feces of Belgian diarrheic suckling piglets

Sebastiaan TheunsPhilip VytLowiese DesmaretsInge RoukaertsElisabeth HeylenMark ZellerJelle MatthijnssensHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Productive replication of nephropathogenic infectious bronchitis virus in peripheral blood monocytic cells, a strategy for viral dissemination and kidney infection in chickens

Vishwanatha Reddy Avalakuppa Papi ReddyIvan TrusLowiese DesmaretsYewei LiSebastiaan TheunsHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

2015

Circulation of pig group A and C rotaviruses in Belgian diarrheic suckling pigs and its impact on veterinary diagnostically analyses

Sebastiaan TheunsPhilip VytLowiese DesmaretsInge RoukaertsElisabeth HeylenMark ZellerMarc Van RanstJelle MatthijnssensHans Nauwynck

Complete genome characterization of recent and ancient Belgian pig group A rotaviruses and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

Complete genome characterization of recent and ancient Belgian pig group A rotaviruses and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

A1 Journal Article in JOURNAL OF VIROLOGY

Complete genome sequence of a porcine epidemic diarrhea virus from a novel outbreak in Belgium, January 2015

Sebastiaan TheunsNádia Conceição-NetoIsaura ChristiaensMark ZellerLowiese DesmaretsInge RoukaertsDelphine AcarElisabeth HeylenJelle MatthijnssensHans Nauwynck

A2 Journal Article in MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Fecal virome analysis from a diarrhea outbreak in Belgian fattening pigs reveals novel divergent porcine picobirnaviruses

Nadia Conceição-NetoSebastiaan TheunsKwe Claude YindaMark ZellerElisabeth HeylenIsaura ChristiaensLowiese DesmaretsInge RoukaertsDelphine AcarMarc Van Ranst et al.

Genetic characterization of the Belgian nephropathogenic infectious bronchitis virus (NIBV) reference strain B1648

Vishwanatha Reddy Avalakuppa Papi ReddySebastiaan TheunsInge RoukaertsMark ZellerJelle MatthijnssensHans Nauwynck

A1 Journal Article in VIRUSES-BASEL

MCMV exploits the spleen as a transfer hub for systemic dissemination upon oronasal inoculation

Shunchuan ZhangJun XiangSebastiaan TheunsLowiese DesmaretsHans Nauwynck

Phylogenetic analysis of feline immunodeficiency virus strains from naturally infected cats in Belgium and The Netherlands

Inge RoukaertsSebastiaan TheunsElien TaffinSylvie DaminetHans Nauwynck

A1 Journal Article in VIRUS RESEARCH

Porcine rotavirus infections in Belgian piglets and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsHans NauwynckJelle Matthijnssens

Successive subclinical group A rotavirus infections in piglets after weaning on a closed Belgian pig farm

Sebastiaan TheunsLowiese DesmaretsInge RoukaertsIsaura ChristiaensElisabeth HeylenMark ZellerMarc Van RanstJelle MatthijnssensHans Nauwynck

The fecal virome of a Belgian non-diarrheic piglet contains group A and C rotaviruses, and an astro- and enterovirus

Sebastiaan TheunsNadia Conceição-NetoElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

Virus replication cycle of white spot syndrome virus in secondary cell cultures from the lymphoid organ of Litopenaeus vannamei

Wenfeng LiLowiese DesmaretsGaëtan De GryseSebastiaan TheunsVo Van TuanThuong Van KhuongPeter BossierHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

2014

Complete genome characterization of recent and ancient Belgian pig group A rotaviruses and assessment of their evolutionary relationship with human rotaviruses

Sebastiaan TheunsElisabeth HeylenMark ZellerInge RoukaertsLowiese DesmaretsMarc Van RanstHans NauwynckJelle Matthijnssens

Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenInge RoukaertsHans Nauwynck

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response

Annelike DedeurwaerderDominique OlyslaegersLowiese DesmaretsInge RoukaertsSebastiaan TheunsHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response

Annelike DedeurwaerderDelphine AcarDominique OlyslaegersLowiese DesmaretsInge RoukaertsSebastiaan TheunsHans Nauwynck

Phylogenetic analysis of FIV strains from naturally infected cats in Belgium and the Netherlands

Inge RoukaertsSebastiaan TheunsElien TaffinSylvie DaminetHans Nauwynck

Phylogenetic analysis of FIV strains from naturally infected cats in Belgium and the Netherlands.

Inge RoukaertsSebastiaan TheunsElien TaffinSylvie DaminetHans Nauwynck

Porcine group A rotaviruses with heterogeneous VP7 and VP4 genotype combinations can be found together with enteric bacteria on Belgian swine farms

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderInge RoukaertsMarc Van RanstJelle MatthijnssensHans Nauwynck

A1 Journal Article in VETERINARY MICROBIOLOGY

Role of sialic acids in feline enteric coronavirus infections

Lowiese DesmaretsSebastiaan TheunsInge RoukaertsDelphine AcarHans Nauwynck

A1 Journal Article in JOURNAL OF GENERAL VIROLOGY

Role of sialic acids in feline enteric coronaviruses infections

Lowiese DesmaretsSebastiaan TheunsInge RoukaertsDelphine AcarHans Nauwynck

Unraveling the role of porcine group A rotaviruses in the pathogenesis of piglet diarrhea and assessment of their genetic constellation

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderInge RoukaertsMarc Van RanstJelle MatthijnssensHans Nauwynck

2013

Complete genome analysis of Belgian porcine rotaviruses reveals a rather conserved porcine-like genotype constellation, despite large genetic diversity of VP7 and VP4

Sebastiaan TheunsElisabeth HeylenMark ZellerMarc Van RanstJelle MatthijnssensHans Nauwynck

Contrasting replication of feline enteric coronavirus and feline infectious peritonitis virus in newly established feline intestinal epithelial cell cultures

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenHannah DewerchinHans Nauwynck

Diagnosis of porcine rotavirus infections by RT-qPCR and RT-PCR reveals a possible synergism between enteric bacteria and genetically heterogeneous porcine rotaviruses in Belgium

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderMarc Van RanstJelle MatthijnssensHans Nauwynck

Enteropathogens in pups from pet shops and breeding facilities

Sofie DupontPatrick ButayeEdwin ClaereboutSebastiaan TheunsLuc DuchateauIsabel Van de MaeleSylvie Daminet

A1 Journal Article in JOURNAL OF SMALL ANIMAL PRACTICE

Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenInge RoukaertsHans Nauwynck

Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronaviruses

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenInge RoukaertsHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Feline peripheral blood mononuclear cell cultivation: cell population evolution, FIV receptor expression, and FIV replication

Inge RoukaertsDominique OlyslaegersLowiese DesmaretsSebastiaan TheunsAnnelike DedeurwaerderHans Nauwynck

ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response

Annelike DedeurwaerderDominique OlyslaegersLowiese DesmaretsInge RoukaertsSebastiaan TheunsHans Nauwynck

Use of a new RT-qPCR assay for diagnosis of genetically heterogeneous porcine group A rotaviruses in Belgium reveals a possible synergism with enteric bacteria

Sebastiaan TheunsLowiese DesmaretsElisabeth HeylenMark ZellerAnnelike DedeurwaerderMarc Van RanstJelle MatthijnssensHans Nauwynck

2012

Contrasting replication kinetics of feline enteric coronavirus and feline infectious peritonitis virus in newly established feline intestinal epithelial cell cultures

Lowiese DesmaretsSebastiaan TheunsDominique OlyslaegersAnnelike DedeurwaerderBen VermeulenHannah DewerchinHans Nauwynck