Research Explorer

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Researcher

Sasker Grootjans

Awards & Distinctions

13 Results

2017

Initiation and execution mechanisms of necroptosis : an overview

Sasker GrootjansTom Vanden BerghePeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability

M JeongE-W LeeD SeongJ SeoJ-H KimSasker GrootjansS-Y KimPeter VandenabeeleJ Song

A1 Journal Article in ONCOGENE

2016

A real-time fluorometric method for the simultaneous detection of cell death type and rate

Sasker GrootjansBehrouz HassanniaIris DelrueVera GoossensBartosz WiernickiYves DondelingerMathieu BertrandDmitri KryskoMarnik VuylstekePeter Vandenabeele et al.

A1 Journal Article in NATURE PROTOCOLS

Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells

Philippe De GrooteSasker GrootjansSaskia LippensChantal EichpergerKirsten LeursIrene KahrGiel TangheInge BruggemanWouter De SchamphelaireCorinne Urwyler et al.

A1 Journal Article in BIOTECHNIQUES

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Özge CanliYasemin B AlankuşSasker GrootjansNaidu VegiLothar HültnerPhilipp S HoppeTimm SchroederPeter VandenabeeleGeorg W BornkammFlorian R Greten

A1 Journal Article in BLOOD

Identification of potential receptor interacting protein kinase 1 substrates during necroptosis

Sasker GrootjansPeter Vandenabeele

2014

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten RemijsenVera GoossensSasker GrootjansC Van den HauteNele VanlangenakkerYves DondelingerRia RoelandtInge BruggemanAmanda GonçalvesMathieu Bertrand et al.

A1 Journal Article in CELL DEATH & DISEASE

Methods to study and distinguish necroptosis

Sasker GrootjansVera GoossensPeter VandenabeeleTom Vanden Berghe

Bookchapter in Necrotic cell death

2013

Determination of apoptotic and necrotic cell death in vitro and in vivo

Tom Vanden BergheSasker GrootjansVera GoossensYves DondelingerDmitri KryskoNozomi TakahashiPeter Vandenabeele

A1 Journal Article in METHODS

Necrostatin-1 blocks both RIPK1 and IDO: consequences for the study of cell death in experimental disease models

Peter VandenabeeleSasker GrootjansNico CallewaertNozomi Takahashi

Editorial material

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

Yves DondelingerMiguel AguiletaVera GoossensChristel DubuissonSasker GrootjansE DejardinPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2012

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Nozomi TakahashiLinde DuprezSasker GrootjansAnje CauwelsWim NerinckxJB DuHadawayVera GoossensRia RoelandtFilip Van HauwermeirenClaude Libert et al.

A1 Journal Article in CELL DEATH & DISEASE

Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide

Maria Regina Orofino KreugerSasker GrootjansMaique W BiavattiPeter VandenabeeleKatharina D'Herde

A1 Journal Article in ANTI-CANCER DRUGS