Research Explorer

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Researcher

Sari Deketelaere

Publications & Research Data

Awards & Distinctions

18 Results

2025

Staudinger β-lactam synthesis via continuous flow chemistry

Sari DeketelaereStefan DesimpelReinout Van KerrebroeckLander DelputteEmma VandenheedeMatthias D'hoogheChristian Stevens

A1 Journal Article in JOURNAL OF FLOW CHEMISTRY

Synthesis of 3-Amino-β-lactams through Selective Imination of 3-Oxo-β-lactams

Sari DeketelaereEmma VandenheedeNicola PiensLore CoolsLieselotte CrulLotte DemeurisseKaren MolletChristian StevensMatthias D'hooghe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

2024

Synthesis of pyrrolidine-fused β-lactams as potential β-lactamase inhibitors

Sari DeketelaereCarlos Diez-PozaMargot AelbrechtJonas MortierBram Van Den BosscheJorick FranceusTom DesmetKristof Van HeckeChristian StevensMatthias D'hooghe

A1 Journal Article in ASIAN JOURNAL OF ORGANIC CHEMISTRY

Unlocking the secrets of β-lactams : exploring reactivity and application for the synthesis of bioactive heterocycles

Sari DeketelaereMatthias D'hoogheChristian Stevens

2023

Engineering Comamonas testosteroni for the production of 2-pyrone-4,6-dicarboxylic acid as a promising building block

Tom DelmulleStijn BovijnSari DeketelaereMartijn CasteleinTom ErauwMatthias D'hoogheWim Soetaert

A1 Journal Article in MICROBIAL CELL FACTORIES

Synthesis of 4‐imidoyl‐, 4‐oxiranyl‐ and 4‐propargyloxyphenyl‐substituted β‐lactam building blocks

Sari DeketelaereGurkirat KaurNicola PiensDaan DeturckRobin DepestelKristof Van HeckeChristian StevensVipan KumarMatthias D'hooghe

A1 Journal Article in JOURNAL OF HETEROCYCLIC CHEMISTRY

2022

Fight against AMR : synthesis of pyrrolidine-fused azetidin-2-ones as potential antibacterials

Sari DeketelaereCarlos Díez PozaMargot AelbrechtJonas MortierBram Van Den BosscheChristian StevensMatthias D'hooghe

Selective iminitation of 3-oxo-β-lactams : new route towards 3-amino-β-lactams

Sari DeketelaereNicola PiensLore Cools

Unexpected formation of N-(chloromethyl)acetamides during attempted Staudinger β-lactam synthesis

Sari DeketelaereElias Van Den BroeckLore CoolsDaan DeturckHannes NaeyaertKristof Van HeckeChristian StevensVeronique Van SpeybroeckMatthias D'hooghe

2021

Unexpected formation of 2,2‐Dichloro‐N‐(chloromethyl)acetamides during attempted Staudinger 2,2‐Dichloro‐β‐lactam synthesis

Sari DeketelaereElias Van Den BroeckLore CoolsDaan DeturckHannes NaeyaertKristof Van HeckeChristian StevensVeronique Van SpeybroeckMatthias D'hooghe

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2019

Reactivity of 3-oxo-β-lactams with respect to primary amines

Sari DeketelaereNicola PiensHannelore GoossensDietmar HertsenLieselotte CrulLotte DemeurisseJelle De MoorElias Van Den BroeckKaren MolletKristof Van Hecke et al.

Reactivity of 3-oxo-β-lactams with respect to primary amines

Sari DeketelaereNicola PiensHannelore GoossensDietmar HertsenLieselotte CrulLotte DemeurisseJelle De MoorElias Van Den BroeckKaren MolletKristof Van Hecke et al.

2018

In silico design and enantioselective synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-β-lactams as inhibitors of penicillin-binding proteins of resistant bacteria

Lena DecuyperSari DeketelaereLore VanparysMarko JukičIzidor SosičEric SauvageAna Maria AmorosoOlivier VerlaineBernard JorisStanislav Gobec et al.

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2017

Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of PBPs of resistant bacteria

Sari DeketelaereLena DecuyperLore VanparysMarko JukičIzidor SosičEric SauvagePaulette CharlierBernard JorisStanislav GobecMatthias D'hooghe

Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of penicillin binding proteins of resistant bacteria

Sari DeketelaereLena DecuyperLore VanparysMarko JukičIzidor SosičEric SauvageAna Maria AmorosoOlivier VerlainePaulette CharlierBernard Joris et al.

Design and synthesis of functionalized monocyclic 3-amino-1-carboxymethyl-beta-lactams as potential inhibitors of penicillin-binding proteins of resistant bacteria

Lena DecuyperSari DeketelaereLore VanparysMarko JukicIzidor SosicEric SauvagePaulette CharlierBernard JorisStanislav GobecMatthias D'hooghe

Reactivity of 3-oxo-β-lactams with respect to primary amines : an experimental and computational approach

Nicola PiensHannelore GoossensDietmar HertsenSari DeketelaereLieselotte CrulLotte DemeurisseJelle De MoorElias Van Den BroeckKaren MolletKristof Van Hecke et al.

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Synthetic approaches toward monocyclic 3-amino-β-lactams

Sari DeketelaereTuyen Van NguyenChristian StevensMatthias D'hooghe

A1 Journal Article in CHEMISTRYOPEN