Research Explorer

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Researcher

Sarah Raevens

Awards & Distinctions

70 Results

2025

Diastolic dysfunction : prevalence and outcome in liver transplantation candidates

Francis VoetMaxim KhalenkowMichel De PauwXavier VerhelstSander LefereAnja GeertsHans Van VlierbergheSarah Raevens

A1 Journal Article in ANNALS OF HEPATOLOGY

Glycomics as prognostic biomarkers of hepatocellular carcinoma : a systematic review

Nicky SomersEmma ButayeLorenz GrossarNele PauwelsAnja GeertsSarah RaevensSander LefereLindsey DevisscherLeander MeurisNico Callewaert et al.

A1 Journal Article in ONCOLOGY LETTERS

Mitochondrial dysfunction characterizes the multigenerational effects of maternal obesity on MASLD

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaTim MeeseYannick GansemansJoél SmetEllen DupontXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

U Journal Article in JHEP Reports

Pulmonary vascular complications of cirrhosis : hepatopulmonary syndrome and portopulmonary hypertension

Maïté VerstraetenSander LefereSarah Raevens

A1 Journal Article in ACTA CLINICA BELGICA

The burden of ascites in cirrhosis

J. BekaertM. AertsS. FrancoisSarah RaevensHelena DegrooteAnja GeertsXavier VerhelstHans Van VlierbergheH. Reynaert

U Journal Article in ACTA CLINICA BELGICA

The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiSara NeytBenedicte DescampsChristian VanhoveXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

Unravelling the coagulation paradox in liver cirrhosis : challenges and insights

Kymentie FerdinandeSarah RaevensJ. DecaesteckerC. De VlooL. SeynhaeveLore HoofXavier VerhelstAnja GeertsKatrien DevreeseH. Degroote et al.

A1 Journal Article in ACTA CLINICA BELGICA

2024

Adipose tissue insulin resistance correlates with disease severity in pediatric metabolic dysfunction-associated steatotic liver disease : a prospective cohort study

Anneleen HeldensEllen DupontLindsey DevisscherMaarten BuytaertXavier VerhelstSarah RaevensHans Van VlierbergheAnja GeertsRuth De BruyneSander Lefere

A1 Journal Article in JOURNAL OF PEDIATRICS

Bariatric surgery is a major independent factor of disease progression in cirrhotic patients with alcohol-related liver disease

Louis OnghenaLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstYves Van NieuwenhoveSander LefereAnja Geerts

Evolution of health-related quality of life in liver transplantation patients in relation to acceptance and metabolic liver disease

Janne SuykensLouis OnghenaFrederik BerrevoetHans Van VlierbergheXavier VerhelstSarah RaevensEric HosteSander LefereAnja GeertsProf dr Carine Poppe

External validation of the IAIHG autoimmune hepatitis response criteria in a multicentric real-world cohort

Lorenz GrossarSarah RaevensChristophe Van SteenkisteIsabelle ColleCharlotte De VlooHans OrlentJeoffrey SchoutenMarie GallantAnnelien Van DriesscheSander Lefere et al.

A1 Journal Article in JHEP REPORTS

External validation of the international autoimmune hepatitis group response criteria in a multicentric real-world cohort

Lorenz GrossarSarah RaevensChristophe Van SteenkisteIsabelle ColleCharlotte De VlooHans OrlentJeoffrey SchoutenMarie GallantAnnelien Van DriesscheSander Lefere et al.

Pre-treatment serum N-glycans predict poor immunotherapy response and survival in hepatocellular carcinoma

Nicky SomersTheresa HoltmannFabian ArtusaEmma ButayeLorenz GrossarSarah RaevensAnja GeertsSander LefereLindsey DevisscherLeander Meuris et al.

Prior metabolic and bariatric surgery is an independent determinant of severity of decompensation in alcohol-associated liver disease

Louis OnghenaYves Van NieuwenhoveHans Van VlierbergheLindsey DevisscherSarah RaevensXavier VerhelstSander LefereAnja Geerts

A1 Journal Article in UNITED EUROPEAN GASTROENTEROLOGY JOURNAL

Recurrent rejections after liver transplantation for hepatocellular carcinoma with stem cell features in an adult patient

Simon MeganckSarah RaevensKymentie FerdinandeXavier VerhelstAnne HoorensHelena DegrooteAnja GeertsHans Van Vlierberghe

A1 Journal Article in ACTA CLINICA BELGICA

Specific glycomic profiles can identify patients at risk of poor transplant-free survival in primary biliary cholangitis

Nicky SomersNikolaos GatselisMaria C. van HooffVasiliki LygouraEmma ButayeLorenz GrossarSarah RaevensAnja GeertsSander LefereLindsey Devisscher et al.

Systematic review : glycomics as diagnostic markers for hepatocellular carcinoma

Emma ButayeNicky SomersLorenz GrossarNele PauwelsSander LefereLindsey DevisscherSarah RaevensAnja GeertsLeander MeurisNico Callewaert et al.

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The association of ultra‐processed food intake with adolescent metabolic dysfunction‐associated steatotic liver disease in the NHANES

Maarten BuytaertDimitri DeclercqFleur DepoorterZerlina CosijnLindsey DevisscherSarah RaevensXavier VerhelstHans Van VlierbergheAnja GeertsRuth De Bruyne et al.

A1 Journal Article in PEDIATRIC OBESITY

The double-edged sword of bariatric surgery : extending the excluded limb can trigger bacterial translocation, liver inflammation and death

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstAnne HoorensYves Van NieuwenhoveAnja Geerts et al.

The role of interleukin-8 in primary sclerosing cholangitis-associated immune cell dysregulation

Lander HeyerickKevin De MuynckZenzi De VosSander LefereJana RoelsNiels VandammeAnja GeertsSarah RaevensXavier VerhelstHans Van Vlierberghe et al.

Transgenerational maternal obesity induces mitochondrial dysfunction and aggravates MASLD, which can be reversed by metabolic drug candidates

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaLindsey DevisscherXavier VerhelstSarah RaevensHans Van VlierbergheRuth De BruyneAnja GeertsSander Lefere

Ultra-processed food intake does not correlate with pediatric MASLD in the National Health and Nutrition Examination Survey

Maarten BuytaertDimitri DeclercqFleur DepoorterZerlina CosijnLindsey DevisscherAnja GeertsXavier VerhelstHans Van VlierbergheSarah RaevensRuth De Bruyne et al.

2023

A remarkable presentation of a massive Budd-Chiari syndrome

Kymentie FerdinandeHelena DegrooteAnja GeertsHans Van VlierbergheXavier VerhelstSarah Raevens

Editorial material

An unusual cause of portal hypertension

Kymentie FerdinandeThibaud LamiroyAnne HoorensXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheAnja Geerts

Editorial material

Application of updated diagnostic criteria for cirrhotic cardiomyopathy : evaluation of its clinical impact in liver transplantation candidates

Maxim KhalenkowFrancis VoetMichel De PauwSander LefereHelena DegrooteXavier VerhelstAnja GeertsHans Van VlierbergheSarah Raevens

Overview of liver organ allocation policies in Europe and the impact on outcome after liver transplantation

Chloë CallantHelena DegrooteSarah RaevensAnja GeertsE. HosteFrederik BerrevoetLuc ColenbieHans Van VlierbergheXavier Verhelst

Patients hospitalized with alcohol-related liver disease and prior bariatric surgery are more prone to develop acute-on-chronic liver failure

Louis OnghenaYves Van NieuwenhoveLaurissa DemeulenaereLindsey DevisscherXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheSander LefereAnja Geerts

A1 Journal Article in LIVER INTERNATIONAL

2022

Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury

Lindsey DevisscherSanne Van CampenhoutSander LefereSarah RaevensLaurentijn TillemanFilip Van NieuwerburghHannelore P. Van EeckhoutteAnne HoorensMichael A. LynesAnja Geerts et al.

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

2021

Pulmonary abnormalities in liver disease : relevance to transplantation and outcome

Sarah RaevensMaxine BoretMichel De PauwMichael B. FallonHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY

Recent advances in the approach to hepatopulmonary syndrome and portopulmonary hypertension

Sarah RaevensAlbert GeertsLindsey DevisscherHans Van VlierbergheChristophe Van SteenkisteIsabelle Colle

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

2020

Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury

Sarah RaevensSanne Van CampenhoutPieter-Jan DebackerSander LefereXavier VerhelstAnja GeertsHans Van VlierbergheIsabelle ColleLindsey Devisscher

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

Sanne Van CampenhoutLaurentijn TillemanSander LefereAster VandierendonckSarah RaevensXavier VerhelstAnja GeertsFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

Vasomodulators and liver transplantation for portopulmonary hypertension : evidence from a systematic review and meta-analysis

Rebecca DerooEric TrepoTom HolvoetMichel De PauwAnja GeertsXavier VerhelstIsabelle ColleHans Van VlierbergheMichael B. FallonSarah Raevens

A1 Journal Article in HEPATOLOGY

2019

Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

A1 Journal Article in HEPATOLOGY

Oral vasodilator treatment and liver transplantation for portopulmonary hypertension : systematic review and meta-analysis of hemodynamic response and prognosis

Rebecca DerooMichel De PauwEric TrepoTom HolvoetAnja GeertsXavier VerhelstIsabelle ColleHans Van VlierbergheSarah Raevens

Outcome of liver transplantation for hepatopulmonary syndrome : a Eurotransplant experience

Sarah RaevensXavier RogiersAnja GeertsXavier VerhelstUndine SamuelMarieke van RosmalenGabriela BerlakovichJean DelwaideOlivier DetryFrank Lehner et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Why pulse oximetry is inaccurate in liver cirrhosis : ancient knowledge

Sarah RaevensIsabelle ColleAnja GeertsHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY

2018

Advances in the approach to pulmonary vascular complications of liver disease

Sarah RaevensIsabelle ColleAnja Geerts

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereF Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytChristian VanhoveAnne HoorensCHRISTINE CASTELEYNXavier Verhelst et al.

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereFrederique Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckS NeytChristian VanhoveAnne HoorensChristophe CasteleynXavier Verhelst et al.

Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

Cu isotope ratio shifts in common bile duct ligated mice and correlates with the degree of cholestatic-induced liver disease

Sanne Van CampenhoutMarta Costas RodriguezAgustina Ari Murti Budi HastutiSarah RaevensAnja GeertsXavier VerhelstFrank VanhaeckeHans Van VlierbergheLindsey Devisscher

Placental growth factor inhibition targets pulmonary angiogenesis and represents a therapy for hepatopulmonary syndrome in mice

Sarah RaevensAnja GeertsAnnelies ParidaensSander LefereXavier VerhelstAnne HoorensJo Van DorpeTania MaesKen BrackeChristophe Casteleyn et al.

A1 Journal Article in HEPATOLOGY

The combination of N-acetylcysteine and anti-MT antibodies as novel therapy for acetaminophen-induced liver injury

Lindsey DevisscherDebby LaukensHannelore Van EeckhoutteSarah RaevensSander LefereAnne HoorensXavier VerhelstM LynesAnja GeertsHans Van Vlierberghe

2017

Anti-placental growth factor therapy attenuates experimental hepatopulmonary syndrome

Sarah RaevensAnnelies ParidaensSander LefereChristophe CasteleynB JonckxXavier VerhelstHans Van VlierbergheChristophe Van SteenkisteAnja GeertsLindsey Devisscher et al.

Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication

Annelies ParidaensSarah RaevensIsabelle ColleEliene BogaertsYves-Paul VandewynckelXavier VerhelstAnne HoorensLeo A van GrunsvenHans Van VlierbergheAnja Geerts et al.

A1 Journal Article in LIVER INTERNATIONAL

Kupffer cell pool is maintained by local proliferation and the differentiation of bone marrow monocytes into short-lived monocyte-derived Kupffer cells during non-alcoholic steatohepatitis and recovery

Lindsey DevisscherCharlotte ScottSander LefereSarah RaevensEliene BogaertsAnnelies ParidaensXavier VerhelstAnja GeertsMartin GuilliamsHans Van Vlierberghe

Modulation of the unfolded protein response by tauroursodeoxycholic acid counteracts apoptotic cell death and fibrosis in a mouse model for secondary biliary liver fibrosis

Annelies ParidaensSarah RaevensLindsey DevisscherEliene BogaertsXavier VerhelstAnne HoorensHans Van VlierbergheLeo van GrunsvenAnja GeertsIsabelle Colle

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool

Lindsey DevisscherCharlotte ScottSander LefereSarah RaevensEliene BogaertsAnnelies ParidaensXavier VerhelstAnja GeertsMartin GuilliamsHans Van Vlierberghe

A1 Journal Article in CELLULAR IMMUNOLOGY

Refractory subacute steatohepatitis after biliopancreatic diversion

Sander LefereAnne HoorensSarah RaevensRoberto TroisiXavier VerhelstHans Van VlierbergheAnja Geerts

Editorial material

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF OBESITY

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

2016

Kinetics of pulmonary angiogenesis in mouse common bile duct ligation-induced liver fibrosis

Sarah RaevensLindsey DevisscherAnnelies ParidaensEliene BogaertsSander LefereYves-Paul VandewynckelCHRISTINE CASTELEYNKen BrackeTania MaesXavier Verhelst et al.

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

Yves-Paul VandewynckelCéline CouckeDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsAster VandierendonckSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

Yves-Paul VandewynckelCéline CouckeDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsAster VandierendonckSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

A1 Journal Article in ONCOTARGET

Placental growth factor inhibition alleviates hepatopulmonary syndrome in mice

Sarah RaevensAnnelies ParidaensSander LefereBart JonckxXavier VerhelstHans Van VlierbergheChristophe Van SteenkisteAnja GeertsLindsey DevisscherIsabelle Colle

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherEliene BogaertsAnnelies ParidaensAnja Van den BusscheSarah RaevensXavier VerhelstChristophe Van SteenkisteBart Jonckx et al.

A1 Journal Article in BMC CANCER

The bile acid tauroursodeoxycholic acid cooperates with N-acetylcysteine in the treatment of experimental acetaminophen-induced hepatotoxicity

Annelies ParidaensLindsey DevisscherSarah RaevensEliene BogaertsYves-Paul VandewynckelXavier VerhelstI MannaertsL Van GrunsvenHans Van VlierbergheIsabelle Colle et al.

The unfolded protein response underlies microenvironmental stress-induced phenotype switching leading to stemness and chemoresistance in human hepatocellular carcinoma

Yves-Paul VandewynckelO GovaereAster VandierendonckDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

2015

Hepatopulmonary syndrome and portopulmonary hypertension : recent knowledge in pathogenesis and overview of clinical assessment

Sarah RaevensAnja GeertsChristophe Van SteenkisteXavier VerhelstHans Van VlierbergheIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

Placental growth factor inhibition modulates the interplay between hypoxia and the unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteB Jonckx et al.

Role of angiogenic factors/cell adhesion markers in serum of cirrhotic patients with hepatopulmonary syndrome

Sarah RaevensStephanie CoulonChristophe Van SteenkisteRoos ColmanXavier VerhelstHans Van VlierbergheAnja GeertsThomas PerkmannThomas HorvatitsValentin Fuhrmann et al.

A1 Journal Article in LIVER INTERNATIONAL

Systematic review of guidelines for management of intermediate hepatocellular carcinoma using the Appraisal of Guidelines Research and Evaluation II instrument

Tom HolvoetSarah RaevensYves-Paul VandewynckelWim Van BiesenKaren GeboesHans Van Vlierberghe

A1 Journal Article in DIGESTIVE AND LIVER DISEASE

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

A1 Journal Article in ONCOTARGET

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstA Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

2014

Prevalence and outcome of diastolic dysfunction in liver transplantation recipients

Sarah RaevensMichel De PauwAnja GeertsFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheIsabelle Colle

A1 Journal Article in ACTA CARDIOLOGICA

2013

Echocardiography for the detection of portopulmonary hypertension in liver transplant candidates: an analysis of cutoff values

Sarah RaevensIsabelle ColleKOEN REYNTJENSAnja GeertsFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheMichel De Pauw

A1 Journal Article in LIVER TRANSPLANTATION

Living related liver transplantation in an adult patient with hepatocellular adenoma and carcinoma 13 years after bone marrow transplantation for Fanconi anemia: a case report

Isabelle ColleGenevieve LaureysSarah RaevensLouis LibbrechtJuliaan LeroyKOEN REYNTJENSAnja GeertsXavier RogiersRoberto TroisiHolger Hoehn et al.

A1 Journal Article in HEPATOLOGY RESEARCH

Oral vasodilator therapy in patients with moderate to severe portopulmonary hypertension as a bridge to liver transplantation

Sarah RaevensMichel De PauwKOEN REYNTJENSAnja GeertsXavier VerhelstFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheIsabelle Colle

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY