Research Explorer

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Researcher

Sarah De Clercq

Awards & Distinctions

7 Results

2013

L-Plastin nanobodies perturb matrix degradation, podosome formation, stability and lifetime in THP-1 macrophages

Sarah De ClercqCiska BoucherieJoël VandekerckhoveJan GettemansAude Guillabert

A1 Journal Article in PLOS ONE

Mapping cytoskeletal protein function in cells by means of nanobodies

Isabel Van AudenhoveKatrien Van ImpeDavid Ruano-GallegoSarah De ClercqKevin De MuynckBerlinda VanlooHanne VerstraeteLuis Á FernándezJan Gettemans

A1 Journal Article in CYTOSKELETON

Modulating L‐plastin function in immune cells by nanobodies : how small bodies can have large consequences

Sarah De ClercqJan Gettemans

Nanobody-induced perturbation of LFA-1/L-plastin phosphorylation impairs MTOC docking, immune synapse formation and T cell activation

Sarah De ClercqOlivier ZwaenepoelEvelien MartensJoël VandekerckhoveAude GuillabertJan Gettemans

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2011

Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist Nutlin-3

Tom Van MaerkenAli RihaniDaniel DreidaxSarah De ClercqNurten YigitJean-Christophe MarineFrank WestermannAnne De PaepeJo VandesompeleFranki Speleman

A1 Journal Article in MOLECULAR CANCER THERAPEUTICS

2010

A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction

Anske Van Den AbbeeleSarah De ClercqAriane De GanckVEERLE DE CORTEBerlinda Van LooSameh Hamdy SororVasundara SrinivasanJan SteyaertJoël VandekerckhoveJan Gettemans

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2008

IMMUNOMODULATION OF CANCER CELL MIGRATION AND INVASION USING RECOMBINANT CAMELID NANOBODIES AGAINST CYTOSKELETAL PROTEINS

Veerle DelanoteAnske Van Den AbbeeleSarah De ClercqAriane De GanckKatrien Van ImpeVeerle De CorteBerlinda VanlooCiska BoucherieJoël VandekerckhoveJan Gettemans