Research Explorer

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Researcher

Sarah Cosyns

38 Results

2022

Chapter four : the tumor immune microenvironment in peritoneal carcinomatosis

Jesse DemuytereSam ErnstJudith van OvostSarah CosynsWim Ceelen

A1 Journal Article in INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY

Computational investigation of the effective forces on droplets during electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC)

Mohammad Rahimi GorjiCharlotte DebbautSarah CosynsWouter WillaertWim Ceelen

In silico modeling of regional droplet deposition during aerosolized intraperitoneal chemotherapy using a patient-inspired geometry

Mohammad Rahimi GorjiCharlotte DebbautSarah CosynsWouter WillaertWim Ceelen

Optimization of intraperitoneal aerosolized drug delivery using computational fluid dynamics (CFD) modeling

Mohammad Rahimi GorjiCharlotte DebbautSarah CosynsWouter WillaertWim Ceelen

A1 Journal Article in SCIENTIFIC REPORTS

Phase I study of intraperitoneal aerosolized nanoparticle albumin based paclitaxel (NAB-PTX) for unresectable peritoneal metastases

Wim CeelenLouis SandraLeen Van de SandeAn VermeulenElke GasthuysDries ReyndersSarah CosynsAnne HoorensWouter Willaert

A1 Journal Article in EBIOMEDICINE

2021

Aerosolization of thermosensitive hydrogels using pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Mohammad Rahimi GorjiHelena BraetCharlotte DebbautSarah CosynsWouter WillaertKatrien RemautWim Ceelen

Analysis of the effect of liquid viscosity on the aerosol distribution during Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) using computational modeling

Mohammad Rahimi GorjiSarah CosynsCharlotte DebbautWouter WillaertWim Ceelen

Debulking and HIPEC for ovarian cancer : effects of perfusion temperature on morbidity and cisplatin pharmacokinetics

Jesse DemuytereCharlotte CarlierWouter WillaertPhilippe TummersHannelore DenysSarah CosynsWim Ceelen

Effect of fluid flow rate and droplet size on spatial aerosol distribution during pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Mohammad Rahimi GorjiSarah CosynsWouter WillaertWim CeelenCharlotte Debbaut

Electrostatic precipitation pressurized intraperitoneal aerosol chemotherapy (ePIPAC) : finding the optimal electrical potential

Mohammad Rahimi GorjiCharlotte DebbautWouter WillaertSarah CosynsWim Ceelen

Exploring high pressure nebulization of pluronic F127 hydrogels for intraperitoneal drug delivery

Helena BraetMohammad Rahimi GorjiCharlotte DebbautSenne CornelisSarah CosynsChris VervaetWouter WillaertWim CeelenStefaan De SmedtKatrien Remaut

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In vitro study of aerosol droplet impact on the peritoneal surface after nebulization using the CapnoPen device

Mohammad Rahimi GorjiSarah CosynsCharlotte DebbautWouter WillaertWim Ceelen

Intraperitoneal aerosolized nanoparticle albumin based paclitaxel (NAB-PTX) for irresectable peritoneal metastases : a first in human phase I study

Wim CeelenLouis SandraLeen Van de SandeAn VermeulenDries ReyndersSarah CosynsAnne HoorensWouter Willaert

2020

Albumin-based cancer therapeutics for intraperitoneal drug delivery : a review

Leen Van de SandeSarah CosynsWouter WillaertWim Ceelen

A1 Journal Article in DRUG DELIVERY

Effects of electrostatic precipitation on IP drug distribution and tissue penetration of nanoparticles

Mohammad Rahimi GorjiLeen Van de SandeCharlotte DebbautWouter WillaertSarah CosynsWim Ceelen

Electrostatic intraperitoneal aerosol delivery of nanoparticles : proof of concept and preclinical validation

Leen Van de SandeMohammad Rahimi GorjiKatharina D'HerdeHelena BraetMolood ShariatiKatrien RemautFei XieCharlotte DebbautSarah CosynsWouter WillaertWim Ceelen

A1 Journal Article in ADVANCED HEALTHCARE MATERIALS

Electrostatic precipitation is a valuable adjunct to pressurized intraperitoneal aerosol chemotherapy : an in vitro study

Leen Van de SandeSarah CosynsWouter WillaertMolood ShariatiHelena BraetKatrien RemautWim Ceelen

Intraperitoneal aerosolized drug delivery : technology, recent developments, and future outlook

Mohammad Rahimi GorjiLeen Van de SandeCharlotte DebbautHelena BraetSarah CosynsKatrien RemautWouter WillaertWim Ceelen

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

2019

Establishment of a rat ovarian peritoneal metastasis model to study pressurized intraperitoneal aerosol chemotherapy (PIPAC)

Leen Van de SandeWouter WillaertSarah CosynsKaat De ClercqMolood ShariatiKatrien RemautWim Ceelen

A1 Journal Article in BMC CANCER

2018

Biology-based surgery : the extent of lymphadenectomy in cancer of the colon

Wouter WillaertSarah CosynsWim Ceelen

A1 Journal Article in EUROPEAN SURGICAL RESEARCH

Intraperitoneal aerosolization of albumin-stabilized paclitaxel nanoparticles (Abraxane™) for peritoneal carcinomatosis : a phase I first-in-human study

Leen Van de SandeSarah CosynsWouter WillaertWim Ceelen

A2 Journal Article in PLEURA AND PERITONEUM

The impact of surgical resection of the primary tumor on the development of synchronous colorectal liver metastasis : a systematic review

Sarah CosynsWim Ceelen

A1 Journal Article in ACTA CHIRURGICA BELGICA

2017

Establishment of a rat model for pressurized intraperitoneal aerosol chemotherapy

Leen Van de SandeWouter WillaertSarah CosynsWim Ceelen

Pressurized IntraPeritoneal Aerosol Chemotherapy for unresectable peritoneal carcinomatosis : experience of 63 procedures

Wouter WillaertLeen Van de SandeSarah CosynsElke Van DaeleDirk Van de PutteYves Van NieuwenhovePiet PattynWim Ceelen

Pressurized intraperitoneal aerosol chemotherapy, a new surgical technique for the treatment of unresectable peritoneal carcinomatosis

Wouter WillaertSarah CosynsLeen Van de SandePiet PattynWim Ceelen

2016

Pressurized intraperitoneal aerosol chemotherapy (PIPAC), a new surgical technique for the treatment of unresectable peritoneal carcinomatosis

Sarah CosynsLeen Van de SandeWim CeelenWouter Willaert

2015

Protective effect of exogenous nitrite in postoperative ileus

Sarah CosynsRomain Lefebvre

A1 Journal Article in BRITISH JOURNAL OF PHARMACOLOGY

2014

Effect of exogenous nitrite in postoperative ileus

Sarah CosynsRomain Lefebvre

Gastrointestinal effects of soluble guanylate cyclase activation by NO-independent compounds and by NO delivery via nitrite

Sarah CosynsRomain Lefebvre

Influence of cinaciguat on gastrointestinal motility in apo-sGC mice

Sarah CosynsLeander HuygheRobrecht ThoonenPeter BrouckaertRomain Lefebvre

A1 Journal Article in NEUROGASTROENTEROLOGY AND MOTILITY

2013

BAY 58-2667 does not improve delayed gastric emptying in APO-SGC mice

Sarah CosynsPeter BrouckaertRomain Lefebvre

Cinaciguat in the gastrointestinal tract of apo-sGC mice

Sarah CosynsPeter BrouckaertRomain Lefebvre

Effect of exogenous nitrite in postoperative ileus

Sarah CosynsRomain Lefebvre

Heme deficiency of soluble guanylate cyclase induces gastroparesis

Sarah CosynsIngeborg DhaeseRobrecht ThoonenAnne VralPeter BrouckaertRomain Lefebvre

A1 Journal Article in NEUROGASTROENTEROLOGY AND MOTILITY

2012

Mechanism of action of BAY 41-2272 in gastrointestinal relaxation

Sarah CosynsRomain Lefebvre

Mechanism of relaxation and interaction with nitric oxide of the soluble guanylate stimulator BAY 41-2272 in mouse gastric fundus and colon

Sarah CosynsRomain Lefebvre

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACOLOGY

2011

Relaxant effect of BAY 41-2272 and BAY 58-2667 in the gastric fundus of apo-sGC mice

Sarah CosynsPeter BrouckaertRomain Lefebvre

Relaxant effect of BAY 41-2272 and BAY 58-2667 in the gastrointestinal tract of apo-sGC mice

Sarah CosynsPeter BrouckaertRomain Lefebvre