Research Explorer

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Researcher

Sarah Bonte

17 Results

2022

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

Joline IngelsLaurenz De CockRupert MayerPam DevrekerKarin WeeningKelly HeynsNele LootensSaskia De SmetMarieke BrusseelStijn De MunterMelissa PilleLore BillietGlenn GoetgelukSarah BonteHanne JansenSandra Van LintGeorges LeclercqTom TaghonBjörn MentenKarim VermaelenFrancis ImpensBart Vandekerckhove

A1 Journal Article in CYTOTHERAPY

2021

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

Sarah BonteStijn De MunterLore BillietGlenn GoetgelukJoline IngelsHanne JansenMelissa PilleLaurenz De CockKarin WeeningTom TaghonGeorges LeclercqBart VandekerckhoveTessa Kerre

A1 Journal Article in ONCOIMMUNOLOGY

TCR-based T cell immunotherapy for AML : multidimensional aids in optimizing treatment and patient identification

Sarah BonteTessa KerreBart Vandekerckhove

2020

Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage

Lore BillietGlenn GoetgelukSarah BonteStijn De MunterLaurenz De CockMelissa PilleJoline IngelsHanne JansenKarin WeeningFilip Van NieuwerburghTessa KerreTom TaghonGeorges LeclercqBart Vandekerckhove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly

Stijn De MunterAlexander Van ParysLayla BralJoline IngelsGlenn GoetgelukSarah BonteMelissa PilleLore BillietKarin WeeningAnnick VerheeJosé Van Der HeydenTom TaghonGeorges LeclercqTessa KerreJan TavernierBart Vandekerckhove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

Sarah BonteStijn De MunterGlenn GoetgelukJoline IngelsMelissa PilleLore BillietTom TaghonGeorges LeclercqBart VandekerckhoveTessa Kerre

A1 Journal Article in ONCOIMMUNOLOGY

2018

Nanobody based dual specific CARs

Stijn De MunterJoline IngelsGlenn GoetgelukSarah BonteMelissa PilleKarin WeeningTessa KerreHinrich AbkenBart Vandekerckhove

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2017

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Yasmine Van CaeneghemStijn De MunterPaola TieppoGlenn GoetgelukKarin WeeningGreet VerstichelSarah BonteTom TaghonGeorges LeclercqTessa KerreReno DebetsDavid VermijlenHinrich AbkenBart Vandekerckhove

A1 Journal Article in ONCOIMMUNOLOGY

In vitro generation of tumor antigen-specific T cells from patient and healthy donor stem cells

Sarah BonteSYLVIA SNAUWAERTGlenn GoetgelukBart VandekerckhoveTessa Kerre

The checkpoint for agonist selection precedes conventional selection in human thymus

Greet VerstichelDavid VermijlenLiesbet MartensGlenn GoetgelukMargreet BrouwerNicolas ThiaultYasmine Van CaeneghemStijn De MunterKarin WeeningSarah BonteGeorges LeclercqTom TaghonTessa KerreYvan SaeysJo Van DorpeHilde CheroutreBart Vandekerckhove

A1 Journal Article in SCIENCE IMMUNOLOGY

2016

Humanized mice to study human T cell development

Sarah BonteSYLVIA SNAUWAERTStijn VanheeAnne-Catherine DolensTom TaghonBart VandekerckhoveTessa Kerre

Bookchapter in T-Cell development : methods and protocols

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells

Yannick WillemenJohan M. J. Van den BerghSarah BonteSebastien AnguilleCarlo HeirmanBarbara MH SteinHerman GoossensTessa KerreKris ThielemansMarc PeetersViggo FI Van TendelooEvelien LJ SmitsZwi N Berneman

A1 Journal Article in ONCOTARGET

2015

Chimeric antigen receptor transgenic, T cell receptor/CD3 negative monospecific T cells generated from cord blood CD34 positive cells

Yasmine Van CaeneghemGlenn GoetgelukKarin WeeningGreet VerstichelSarah BonteTom TaghonGeorges LeclercqFritz OffnerHinrich AbkenTessa KerreBart Vandekerckhove

Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSYLVIA SNAUWAERTM HeemskerkH StaussR StripeckeB VandekerckhoveTessa Kerre

2014

Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSYLVIA SNAUWAERTG GoetgelukM HeemskerkH StaussBart VandekerckhoveTessa Kerre

In vitro and in vivo functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system

Sarah BonteSYLVIA SNAUWAERTGlenn GoetgelukH StaussR StripeckeM HeemskerkYasmine Van CaeneghemGreet VerstichelStijn VanheeBart VandekerckhoveTessa Kerre

In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection

SYLVIA SNAUWAERTGreet VerstichelSarah BonteGlenn GoetgelukStijn VanheeYasmine Van CaeneghemKatrien De MulderCarlo HeirmanHans StaussMiriam HM HeemskerkTom TaghonGeorges LeclercqJean PlumAnton W LangerakKris ThielemansTessa KerreBart Vandekerckhove

A1 Journal Article in LEUKEMIA