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Researcher
Sarah Bonte
Profile
Projects
Publications
Activities
Awards & Distinctions
20
Results
2024
Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion
Stijn De Munter
Juliane L. Buhl
Laurenz De Cock
Alexander Van Parys
Willem Daneels
Eva Pascal
Lucas Deseins
Joline Ingels
Glenn Goetgeluk
Hanne Jansen
et al.
A1
Journal Article
in
CANCER IMMUNOLOGY RESEARCH
2024
2023
Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage
Lore Billiet
Laurenz De Cock
Guillem Sanchez Sanchez
Rupert Mayer
Glenn Goetgeluk
Stijn De Munter
Melissa Pille
Joline Ingels
Hanne Jansen
Karin Weening
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2023
The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation
Melissa Pille
John Avila
Guillem Sanchez Sanchez
Glenn Goetgeluk
Stijn De Munter
Hanne Jansen
Lore Billiet
Karin Weening
Haipeng Xue
Sarah Bonte
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2023
2022
Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials
Joline Ingels
Laurenz De Cock
Rupert Mayer
Pam Devreker
Karin Weening
Kelly Heyns
Nele Lootens
Saskia De Smet
Marieke Brusseel
Stijn De Munter
et al.
A1
Journal Article
in
CYTOTHERAPY
2022
2021
In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality
Sarah Bonte
Stijn De Munter
Lore Billiet
Glenn Goetgeluk
Joline Ingels
Hanne Jansen
Melissa Pille
Laurenz De Cock
Karin Weening
Tom Taghon
et al.
A1
Journal Article
in
ONCOIMMUNOLOGY
2021
TCR-based T cell immunotherapy for AML : multidimensional aids in optimizing treatment and patient identification
Sarah Bonte
Tessa Kerre
Bart Vandekerckhove
Dissertation
2021
2020
Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage
Lore Billiet
Glenn Goetgeluk
Sarah Bonte
Stijn De Munter
Laurenz De Cock
Melissa Pille
Joline Ingels
Hanne Jansen
Karin Weening
Filip Van Nieuwerburgh
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly
Stijn De Munter
Alexander Van Parys
Layla Bral
Joline Ingels
Glenn Goetgeluk
Sarah Bonte
Melissa Pille
Lore Billiet
Karin Weening
Annick Verhee
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources
Sarah Bonte
Stijn De Munter
Glenn Goetgeluk
Joline Ingels
Melissa Pille
Lore Billiet
Tom Taghon
Georges Leclercq
Bart Vandekerckhove
Tessa Kerre
A1
Journal Article
in
ONCOIMMUNOLOGY
2020
2018
Nanobody based dual specific CARs
Stijn De Munter
Joline Ingels
Glenn Goetgeluk
Sarah Bonte
Melissa Pille
Karin Weening
Tessa Kerre
Hinrich Abken
Bart Vandekerckhove
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2018
2017
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities
Yasmine Van Caeneghem
Stijn De Munter
Paola Tieppo
Glenn Goetgeluk
Karin Weening
Greet Verstichel
Sarah Bonte
Tom Taghon
Georges Leclercq
Tessa Kerre
et al.
A1
Journal Article
in
ONCOIMMUNOLOGY
2017
In vitro generation of tumor antigen-specific T cells from patient and healthy donor stem cells
Sarah Bonte
Sylvia Snauwaert
Glenn Goetgeluk
Bart Vandekerckhove
Tessa Kerre
C3
Conference
2017
The checkpoint for agonist selection precedes conventional selection in human thymus
Greet Verstichel
David Vermijlen
Liesbet Martens
Glenn Goetgeluk
Margreet Brouwer
Nicolas Thiault
Yasmine Van Caeneghem
Stijn De Munter
Karin Weening
Sarah Bonte
et al.
A1
Journal Article
in
SCIENCE IMMUNOLOGY
2017
2016
Humanized mice to study human T cell development
Sarah Bonte
Sylvia Snauwaert
Stijn Vanhee
Anne-Catherine Dolens
Tom Taghon
Bart Vandekerckhove
Tessa Kerre
Bookchapter
in
T-Cell development : methods and protocols
2016
The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells
Yannick Willemen
Johan M. J. Van den Bergh
Sarah Bonte
Sebastien Anguille
Carlo Heirman
Barbara MH Stein
Herman Goossens
Tessa Kerre
Kris Thielemans
Marc Peeters
et al.
A1
Journal Article
in
ONCOTARGET
2016
2015
Chimeric antigen receptor transgenic, T cell receptor/CD3 negative monospecific T cells generated from cord blood CD34 positive cells
Yasmine Van Caeneghem
Glenn Goetgeluk
Karin Weening
Greet Verstichel
Sarah Bonte
Tom Taghon
Georges Leclercq
Fritz Offner
Hinrich Abken
Tessa Kerre
et al.
C3
Conference
2015
Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system
Sarah Bonte
Sylvia Snauwaert
M Heemskerk
H Stauss
R Stripecke
B Vandekerckhove
Tessa Kerre
C3
Conference
2015
2014
Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system
Sarah Bonte
Sylvia Snauwaert
G Goetgeluk
M Heemskerk
H Stauss
Bart Vandekerckhove
Tessa Kerre
C3
Conference
2014
In vitro and in vivo functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system
Sarah Bonte
Sylvia Snauwaert
Glenn Goetgeluk
H Stauss
R Stripecke
M Heemskerk
Yasmine Van Caeneghem
Greet Verstichel
Stijn Vanhee
Bart Vandekerckhove
et al.
C3
Conference
2014
In vitro generation of mature, naive antigen-specific CD8⁺ T cells with a single T-cell receptor by agonist selection
Sylvia Snauwaert
Greet Verstichel
Sarah Bonte
Glenn Goetgeluk
Stijn Vanhee
Yasmine Van Caeneghem
Katrien De Mulder
Carlo Heirman
Hans Stauss
Miriam HM Heemskerk
et al.
A1
Journal Article
in
LEUKEMIA
2014