Research Explorer

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Researcher

Sara Van Poecke

Awards & Distinctions

9 Results

2012

Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues

Sara Van PoeckeMatthew O BarrettT Santhosh KumarDavy SinnaeveJosé MartinsKenneth A JacobsonT Kendall HardenSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 5-substituted 2'-deoxyuridine-5'-phosphonate analogues and evaluation of their antiviral activity

Sara Van PoeckeDavy SinnaeveJosé MartinsJan BalzariniSerge Van Calenbergh

A1 Journal Article in NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

2011

Synthesis and biological evaluation of pyrimidine nucleosides and nucleoside phosphonates

Sara Van PoeckeSerge Van Calenbergh

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

Sara Van PoeckeHélène Munier-LehmannOlivier HelynckMatheus FroeyenSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of base-substituted uridine 5'-phosphonate analogues as potential P2Y2 receptor ligands

Sara Van PoeckeMatt BarrettKenneth A JacobsonT Kendall HardenSerge Van Calenbergh

Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors

Sara Van PoeckeAna NegriJolien JanssensNicola SolaroliAnna KarlssonFederico GagoJan BalzariniiSerge Van Calenbergh

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

2010

3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase

Sara Van PoeckeAna NegriFederico GagoIneke Van DaeleNicola SolaroliAnna KarlssonJan BalzariniSerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

2008

From M-tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitors towards mitochondrial thymidine kinase (TK-2) inhibitors

Serge Van CalenberghI Van DaeleSara Van PoeckeM FroeyenH Munier LehmannJ Balzarini

2006

Synthesis of α-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors

Timothy HaemersJochen WiesnerSara Van PoeckeJan GoemanDajana HenschkerEwald BeckHassan JomaaSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS