Research Explorer

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Researcher

Sara Neyt

Publications & Research Data

Awards & Distinctions

53 Results

2026

Cross-modality deep learning denoising for low-dose μSPECT : transfer of PET-trained U-net and diffusion models

Elise TaragolaSara NeytBoxiao YuMaya Abi AklBoris VervenneKuang GongStefaan VandenbergheChristian VanhoveFlorence Marie Muller

A2 Journal Article in CHEMICAL & BIOMEDICAL IMAGING

2025

Astrocyte-targeted connexin43 hemichannel inhibition prevents radiation-induced energy transporter decrease in neurons and astrocytic proBDNF transport to synapses

Steffi SchumacherSara NeytChristian VanhoveLien De SchaepmeesterRobrecht RaedtKatja WitschasLuc Leybaert

A1 Journal Article in GLIA

Cross-modality deep learning for micro-SPECT denoising : transfer of PET-trained U-net and diffusion models

Elise TaragolaSara NeytMaya Abi AklBoris VervenneStefaan VandenbergheChristian VanhoveFlorence Marie Muller

Evaluation of [111In]FAPI-46 via dual-isotope SPECT imaging as a predictive radioligand for [177Lu]FAPI-46 biodistribution and dosimetry in mice

Amber MeskensSara NeytMichaël HenrotteJens DebackerChristian VanhoveFilip De Vos

Fractionated versus single-dose PSMA-targeted radioligand therapy as adjuvant therapy in a murine model for oral squamous cell carcinoma treated with immune checkpoint inhibitors

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherGabriële HoltappelsWouter HuvenneKen KersemansAmber MeskensSara Neyt et al.

Intracerebral haemorrhage leads to late-onset changes in cerebral glucose uptake in rats

Melissa LajtosSara NeytRobrecht RaedtVeerle De HerdtChristian Vanhove

Longitudinal changes in cerebral glucose metabolism and brain connectivity post ICH in the rat collagenase model

Melissa LajtosJonas VanderhaegheLuna MestrumMariska MeersschautSara NeytRobrecht RaedtChristian VanhoveVeerle De Herdt

Prostate-specific membrane antigen-targeted radionuclide therapy as adjunct to Immune checkpoint Inhibition in an immunocompetent murine model for oral squamous cell carcinoma

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherWouter HuvenneKen KersemansSara NeytSylvie RotteyMichael Saerens et al.

Studying metabolic brain connectivity using 2-deoxy-2-[18F]fluoro-D-glucose dynamic positron emission tomography at the single-subject level

Melissa LajtosRobrecht RaedtSara NeytVeerle De HerdtChristian Vanhove

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiSara NeytBenedicte DescampsChristian VanhoveXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

2024

Prostate-specific membrane antigen-targeted radionuclide therapy as a novel therapeutic approach in a syngeneic immunocompetent murine model for oral squamous cell carcinoma

Michaël HenrotteDavid CreytensFilip De VosBenedicte DescampsLindsey DevisscherWouter HuvenneKen KersemansSara NeytChristian VanhoveJens Debacker

The development of 177Lu-DOTA-CC-PSMA following a unified “Click Chemistry” protocol of synthesizing metal nuclide-conjugated radiopharmaceuticals

Xiaobei ZhengShuai XueZhongqi ZhaoShuxin JinShuhua HeLina JiaZheng LiChristian VanhoveFilip De VosZijun Kuang et al.

A2 Journal Article in EJNMMI RADIOPHARMACY AND CHEMISTRY

2020

Anti-human PD-L1 Nanobody for immuno-PET imaging : validation of a conjugation strategy for clinical translation

Jessica BridouxKatrijn BroosQuentin LecocqPieterjan DebieCharlotte MartinSteven BalletGeert RaesSara NeytChristian VanhoveKarine Breckpot et al.

A1 Journal Article in BIOMOLECULES

Improved detection of molecular markers of atherosclerotic plaques using sub-millimeter PET imaging

Jessica BridouxSara NeytPieterjan DebieBenedicte DescampsNick DevoogdtFrederik CleerenGuy BormansAlexis BroisatVicky CaveliersCatarina Xavier et al.

A1 Journal Article in MOLECULES

2019

Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

A1 Journal Article in HEPATOLOGY

In vivo measurement of hepatic drug transporter inhibition with radiolabeled bile acids

Stef De LombaerdeSara NeytChristian VanhoveFilip De Vos

Bookchapter in Experimental cholestasis research

Validation of hepatobiliary transport PET imaging in liver function assessment : evaluation of 3β-[18F]FCA in mouse models of liver disease

Stef De LombaerdeLindsey DevisscherJeroen VerhoevenSara NeytHans Van VlierbergheChristian VanhoveFilip De Vos

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

2018

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereF Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytChristian VanhoveAnne HoorensCHRISTINE CASTELEYNXavier Verhelst et al.

Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

Evaluating hepatobiliary transport with 18F labeled bile acids : the effect of radiolabel position and bile acid backbone on radiosynthesis, in vitro and in vivo performance

Stef De LombaerdeKen KersemansSara NeytJeroen VerhoevenChristian VanhoveFilip De Vos

Evaluating hepatobiliary transport with 18F-labeled bile acids : the effect of radiolabel position and bile acid structure on radiosynthesis and in vitro and in vivo performance

Stef De LombaerdeKen KersemansSara NeytJeroen VerhoevenChristian VanhoveFilip De Vos

A1 Journal Article in CONTRAST MEDIA & MOLECULAR IMAGING

Evaluation of 3b-[18F]Fluorocholic acid in hepatocellular carcinoma bearing mice

Stef De LombaerdeLindsey DevisscherJeroen VerhoevenSara NeytChristian VanhoveFilip De Vos

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo

Emiel De JaeghereElly De VlieghereJasper Van HoorickSandra Van VlierbergheGlenn WagemansLeen PietersElodie MelsensMarleen PraetJo Van DorpeMatthieu Boone et al.

A1 Journal Article in BIOMATERIALS

Magnetic resonance imaging (MRI) of third molars in forensic age estimation : validation of the Gent and Graz protocols

Jannick De TobelGriet ParmentierInès PhlypoBenedicte DescampsSara NeytWim Van De VeldePatrick ThevissenKoenraad Verstraete

Species-dependent extracranial manifestations of a brain seeking breast cancer cell line

Valerie De MeulenaereSara NeytBert VandeghinstePieter MolletOlivier De WeverElke DecrockLuc LeybaertIngeborg GoethalsChristian VanhoveBenedicte Descamps et al.

A1 Journal Article in PLOS ONE

2017

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis

Sophie Van WeldenMartine De VosBen WielockxSimon TavernierMelissa DullaersSara NeytBenedicte DescampsLindsey DevisscherSarah DevrieseLien Van den Bossche et al.

A1 Journal Article in JOURNAL OF PATHOLOGY

Heterocellular 3D scaffolds as biomimetic of peritoneal metastases

Elly De VlieghereEmiel De JaeghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytBruno De GeestPeter DubruelWim Ceelen et al.

Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo

Emiel De JaeghereElly De VlieghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytRouba GhobeiraRino MorentJo Van Dorpe et al.

Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo

Elly De VlieghereEmiel De JaeghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytBruno De GeestPeter DubruelWim Ceelen et al.

Heterocellular 3D scaffolds as biomimetic of peritoneal metastasis in vitro and in vivo

Elly De VlieghereEmiel De JaeghereJasper Van HoorickGlenn WagemansLeen PietersElodie MelsensSara NeytBruno De GeestPeter DubruelWim Ceelen et al.

Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice

Stef De LombaerdeSara NeytKen KersemansJeroen VerhoevenLindsey DevisscherHans Van VlierbergheChristian VanhoveFilip De Vos

A1 Journal Article in PLOS ONE

Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid, a radiolabeled bile acid to detect drug-induced cholestasis in preclinical drug development

Stef De LombaerdeSara NeytKen KersemansJeroen VerhoevenLindsey DevisscherHans Van VlierbergheChristian VanhoveFilip De Vos

2016

In vivo evaluation of blood based and reference tissue based PET quantifications of [11C]DASB in the canine brain

Nick Van LaekenOlivia TaylorIngeborgh PolisSara NeytKen KersemansAndre DobbeleirJimmy SaundersIngeborg GoethalsKathelijne PeremansFilip De Vos

A1 Journal Article in PLOS ONE

Non-invasive visualisation and quantification of (disturbed) hepatobiliary transport

Sara NeytFilip De VosChristian Vanhove

Synthesis, in vitro and in vivo small-animal SPECT evaluation of novel technetium labeled bile acid analogues to study (altered) hepatic transporter function

Sara NeytMaarten VliegenBjorn VerreetStef De LombaerdeKim BraeckmanChristian VanhoveMaarten Thomas HuismanCaroline DumolynKen KersemansFabian Hulpia et al.

A1 Journal Article in NUCLEAR MEDICINE AND BIOLOGY

2015

Effect of Cx-mimetic peptide administration on breast cancer brain metastasis development: a preclinical serial MRI study

Valerie De MeulenaereElke DecrockSara NeytOlivier De WeverFilip De VosChristian VanhoveHannelore DenysBenedicte DescampsKarel Deblaere

Effect of GAP27 on breast cancer brain metastasis development: initial results

Valerie De MeulenaereElke DecrockSara NeytOlivier De WeverFilip De VosChristian VanhoveHannelore DenysBenedicte DescampsKarel Deblaere

Multi-modality imaging in a pre-clinical model of developing rat brain metastases: initial results

Valerie De MeulenaereBenedicte DescampsSara NeytOlivier De WeverElke DecrockFilip De VosChristian VanhoveKarel Deblaere

Multi-modality imaging in a pre-clinical model of developing rat brain metastases: initial results

Valerie De MeulenaereBenedicte DescampsSara NeytElke DecrockOlivier De WeverFilip De VosChristian VanhoveKarel Deblaere

Multi-modality imaging in a pre-clinical model of developing rat brain metastases: initial results

Valerie De MeulenaereBenedicte DescampsSara NeytOlivier De WeverElke DecrockFilip De VosChristian VanhoveKarel Deblaere

2014

Evaluation of the PET-radioligand 11C DASB in dogs

Nick Van LaekenOlivia TaylorAndré DobbeleireIngeborgh PolisEva VandermeulenTim BosmansSara NeytKen KersemansIngeborg GoethalsKathelijne Peremans et al.

Molecular MRI in preclinical research

Benedicte DescampsSara NeytFilip De VosValerie De MeulenaereElke DecrockJulie BolcaenIngeborg GoethalsOlivier De WeverTom BoterbergKarel Deblaere et al.

Molecular MRI in preclinical research

Benedicte DescampsSara NeytFilip De VosValerie De MeulenaereElke DecrockJulie BolcaenIngeborg GoethalsOlivier De WeverTom BoterbergKarel Deblaere et al.

Six-weeks follow-up of developing metastases in the rat brain: preliminary results of a multi-modal imaging approach

Valerie De MeulenaereBenedicte DescampsSara NeytOlivier De WeverFilip De VosChristian VanhoveKarel Deblaere

Targeting radiation-induced neuroinflammation using ICAM-MPIO

Benedicte DescampsSara NeytCaroline DumolynFilip De VosElke DecrockValerie De MeulenaereJulie BolcaenIngeborg GoethalsTom BoterbergChristian Vanhove et al.

Targeting radiation-induced neuroinflammation using ICAM-MPIO

Benedicte DescampsSara NeytCaroline DumolynFilip De VosElke DecrockValerie De MeulenaereJulie BolcaenIngeborg GoethalsTom BoterbergChristian Vanhove et al.

2013

99mTc-mebrofenin disposition in chimeric mice with a humanized liver

Sara NeytPhilip MeulemanLieven VerhoyeChristian VanhoveGeert MannensFilip De Vos

Generation and in vivo characterization of a chimeric αvβ5-targeting antibody 14C5 and its derivatives

Caroline DumolynSteve SchoonoogheLieselotte MoermanSara NeytJurgen HaustraeteFilip De Vos

A2 Journal Article in EJNMMI RESEARCH

In vivo magnetic resonance imaging of acute radiation induced inflammation using ICAM1 targeted micron-sized particles of iron oxide (ICAM-MPIO)

Benedicte DescampsSara NeytElke DecrockFilip De VosCaroline DumolynCaroline Van den BroeckeMICHAEL NOEJulie BolcaenIngeborg GoethalsTom Boterberg et al.

In vivo visualization and quantification of (disturbed) Oatp-mediated hepatic uptake and Mrp2-mediated biliary excretion of 99mTc-mebrofenin in mice

Sara NeytMaarten T HuismanChristian VanhoveHilde De ManMaarten VliegenLieselotte MoermanCaroline DumolynGeert MannensFilip De Vos

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Non-invasive method to obtain blood curves of 99mTc-mebrofenin

Sara NeytMaarten T HuismanCaroline DumolynMaarten VliegenChristian VanhoveGeert MannensFilip De Vos

2012

Molecular imaging as a non-invasive tool to visualize impaired hepatobiliary transporter function in Oatp1a/1b and Mrp2 knock-out mice

Sara NeytMaarten T HuismanGeert MannensHilde De ManMaarten VliegenCaroline DumolynChristian VanhoveFilip De Vos

2011

In vivo µSPECT visualization of transport-mediated hepatic uptake and efflux of 99mTc-mebrofenin, and inhibition thereof with rifampicin

Sara NeytMaarten T HuismanGeert MannensHilde De ManMaarten VliegenLieselotte MoermanFilip De Vos