Research Explorer

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Researcher

Sara Kenis

7 Results

2016

Synthesis of trifluoromethylated azetidines, aminopropanes, 1,3-oxazinanes, and 1,3-oxazinan-2-ones starting from 4-trifluoromethyl-β-lactam building blocks

Hang Dao ThiLena DecuyperKaren MolletSara KenisNorbert De KimpeTuyen Van NguyenMatthias D'hooghe

A1 Journal Article in SYNLETT

2014

Selective synthesis of functionalized trifluoromethylated pyrrolidines, piperidines, and azepanes starting from 1-tosyl-2-(trifluoromethyl)aziridine

Jeroen DolfenSara KenisKristof Van HeckeNorbert De KimpeMatthias D'hooghe

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2013

Nucleophile-directed selective transformation of cis-1-tosyl-2-toxyloxymethyl-3-(trifluoromethyl)aziridine into aziridines, azetidines, and benzo-fused dithianes, oxathianes, dioxanes, and (thio)morpholines

Sara KenisMatthias D'hoogheGuido VerniestMaaike ReybroeckTuyet Anh Dang ThiChinh Pham TheTham Thi PhamKarl W TörnroosNguyen Van TuyenNorbert De Kimpe

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of α-(trifluoromethyl)aziridines and -azetidines and their transformations into novel CF₃-substituted amines and heterocyclic systems

Sara KenisNorbert De KimpeMatthias D'hooghe

2012

Synthesis of 1-alkyl-2-(trifluoromethyl)azetidines and their regiospecific ring opening toward diverse α-(trifluoromethyl)amines via intermediate azetidinium salts

Sara KenisMatthias D'hoogheGuido VerniestAnh Dang Thi TuyetChinh Pham TheTuyen Van NguyenNorbert De Kimpe

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

2011

Straightforward synthesis of 1-alkyl-2-(trifluoromethyl)aziridines starting from 1,1,1-trifluoroacetone

Sara KenisMatthias D'hoogheGuido VerniestVinh Duc NguyenAnh Dang Thi TuyetTuyen Van NguyenNorbert De Kimpe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores

Matthias D'hoogheSara KenisKarel VervischCarmen LateganPeter SmithKelly ChibaleNorbert De Kimpe

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY