Research Explorer

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Researcher

Sabitri Ghimire

Publications & Research Data

Awards & Distinctions

20 Results

2018

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background

Sabitri GhimireMargot Van der JeughtJitesh NeupaneMatthias S RoostJasper AnckaertMina PopovicFilip Van NieuwerburghPieter MestdaghJo VandesompeleDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

2016

Inhibition of Rho-associated protein kinase (ROCK) in mouse embryos affects trophectoderm formation and blastocyst development, but still allows subsequent stem cell derivation

Sabitri GhimireMargot Van der JeughtJitesh NeupanePetra De SutterBjörn Heindryckx

Manipulating cell fate in mouse embryos and embryonic stem cells

Sabitri GhimirePetra De SutterBjörn Heindryckx

2015

Alternative routes to induce naive pluripotency in human embryonic stem cells

Galbha DuggalSharat WarrierSabitri GhimireDorien BroekaertMargot Van der JeughtSylvie LiermanTom DerooLuc PeelmanAnn Van SoomMaria Cornelissen et al.

A1 Journal Article in STEM CELLS

Application of small molecules favoring naive pluripotency during human embryonic stem cell derivation

Margot Van der JeughtJasin TaelmanGalbha DuggalSabitri GhimireSylvie LiermanSusana Marina Chuva de Sousa LopesDieter DeforceTom DerooPetra De SutterBjörn Heindryckx

A1 Journal Article in CELLULAR REPROGRAMMING

Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneSabitri GhimireMado VandewoestyneYuechao LuJan GerrisRudy Van CosterTom DerooDieter DeforceStijn VansteelandtPetra De Sutter et al.

A1 Journal Article in CELL REPORTS

Derivation conditions affect pluripotency and differentiation propensity of mouse embryonic stem cells

Sabitri GhimireMargot Van der JeughtJitesh NeupaneFilip Van NieuwerburghDieter DeforceSusana Marina Chuva de Sousa LopesPetra De SutterBjörn Heindryckx

Inhibition of transforming growth factor β signaling promotes epiblast formation in mouse embryos

Sabitri GhimireBjörn HeindryckxMargot Van der JeughtJitesh NeupaneThomas O'LearySylvie LiermanWinnok De VosSusana Marina Chuva de Sousa LopesTom DerooPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2014

A systematic analysis of the suitability of preimplantation genetic diagnosis for mitochondrial diseases in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianSylvie LiermanRudy Van CosterJan GerrisTom Deroo et al.

A1 Journal Article in HUMAN REPRODUCTION

Assessment of cellular heterogeneity in the level of mitochondrial DNA heteroplasmy in mouse embryonic stem cells

Jitesh NeupaneBjörn HeindryckxMado VandewoestyneSabitri GhimireYuechao LuRudy Van CosterDieter DeforceTom DerooPetra De Sutter

Assessment of nuclear transfer techniques to prevent the transmission of heritable mitochondrial disorders without compromising embryonic development competence in mice

Jitesh NeupaneMado VandewoestyneSabitri GhimireYuechao LuChen QianRudy Van CosterJan GerrisTom DerooDieter DeforcePetra De Sutter et al.

A1 Journal Article in MITOCHONDRION

Inhibition of TGFß signaling supports embryonic stem cell derivation and the ground state of pluripotency in mouse

Sabitri GhimireBjörn HeindryckxJitesh NeupaneDieter DeforceTom DerooPetra De Sutter

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtBjörn HeindryckxThomas O'LearyGalbha DuggalSabitri GhimireSylvie LiermanNadine Van RoySusana Marina Chuva de Sousa LopesTom DerooDieter Deforce et al.

A1 Journal Article in HUMAN REPRODUCTION

2013

Nuclear transfer can prevent mitochondrial DNA carry-over without compromising embryonic development potential in mice

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxTom DerooYuechao LuSabitri GhimireSylvie LiermanChen QianDieter DeforcePetra De Sutter

The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation

Margot Van der JeughtThomas O'LearySabitri GhimireSylvie LiermanGalbha DuggalKaren VersierenDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2012

Dose-dependent effect of inhibition of the transforming growth factor beta pathway during early mouse lineage segregation

Sabitri GhimireMargot Van der JeughtJitesh NeupaneSylvie LiermanThomas O'LearySusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuChen QianDieter DeforcePetra De Sutter

Reliability of pre-implantation genetic diagnosis in a heteroplasmic mitochondrial mouse model

Jitesh NeupaneMado VandewoestyneBjörn HeindryckxSabitri GhimireYuechao LuSylvie LiermanChen QianDieter DeforcePetra De Sutter

The TGFβ pathway plays a pivotal role in early embryo lineage segregation

Margot Van der JeughtSabitri GhimireThomas O'LearySylvie LiermanDieter DeforceSusana Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter

The TGFβ pathway plays a pivotal role in early embryo lineage segregation in both mouse and human

Margot Van der JeughtSabitri GhimireThomas O'LearySylvie LiermanDieter DeforceSusana Marina Chuva de Sousa LopesBjörn HeindryckxPetra De Sutter