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Researcher
Ruth Wittoek
Profile
Projects
Publications
Activities
Awards & Distinctions
67
Results
2024
Neuropathic-like pain in knee osteoarthritis : exploring differences in knee loading and inflammation : a cross-sectional study
Paolo Dainese
Sophie De Mits
Ruth Wittoek
Ans Van Ginckel
Wouter Huysse
Hanne Mahieu
Jan Stautemas
Patrick Calders
A1
Journal Article
in
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
2024
RANKL blockade for erosive hand osteoarthritis : a randomized placebo-controlled phase 2a trial
Ruth Wittoek
Gust Verbruggen
Tine Vanhaverbeke
Roos Colman
Dirk Elewaut
A1
Journal Article
in
NATURE MEDICINE
2024
Validation of HAND OA US inflammatory and structural damage score (HOUSE) for thumb-base joints: systematic review on truth and discrimination
Marion C Kortekaas
Tine Vanhaverbeke
Helen I Keen
Lene Terslev
Hilde B Hammer
Maria Antonietta D’Agostino
Ruth Wittoek
[missing] OMERACT Hand OA US Working Group
Ingrid Möller
Alexander Mathiessen
et al.
U
Journal Article
in
Rheumatology
2024
2023
Associations between markers of inflammation and altered pain perception mechanisms in people with knee osteoarthritis : a systematic review
Paolo Dainese
Hanne Mahieu
Sophie De Mits
Ruth Wittoek
Jan Stautemas
Patrick Calders
A1
Journal Article
in
RMD OPEN
2023
Exploring pain, inflammation, and loading in knee osteoarthritis : implications for self-management strategies
Paolo Dainese
Patrick Calders
Ruth Wittoek
Ans Van Ginckel
Dissertation
2023
Structural ultrasound of joints and tendons in healthy children : development of normative data
Ruth Wittoek
Céline Decock
Nele Dewaele
Lara Arnold
Pieter Baeyens
Ignace De Schrijver
Lisa Pardaens
Ioannis Raftakis
Thomas Renson
Charline Rinkin
et al.
A1
Journal Article
in
PEDIATRIC RHEUMATOLOGY
2023
2022
Association between knee inflammation and knee pain in patients with knee osteoarthritis : a systematic review
Paolo Dainese
Karsten Vanden Wyngaert
Sophie De Mits
Ruth Wittoek
Ans Van Ginckel
Patrick Calders
A1
Journal Article
in
OSTEOARTHRITIS AND CARTILAGE
2022
Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases : a proof of concept study
My Kieu Ha
Esther Bartholomeus
Luc Van Os
Julie Dandelooy
Julie Leysen
Olivier Aerts
Vasiliki Siozopoulou
Eline De Smet
Jan Gielen
Khadija Guerti
et al.
A1
Journal Article
in
PEDIATRIC RHEUMATOLOGY
2022
Development of radiographic classification criteria for hand osteoarthritis : a methodological report (phase 2)
Ida K Haugen
David Felson
Abhishek Abhishek
Francis Berenbaum
John James Edwards
Gabriel Herrero Beaumont
Merete Hermann-Eriksen
Catherine L Hill
Mariko Ishimori
Helgi Jonsson
et al.
A1
Journal Article
in
RMD OPEN
2022
Ultrasonography of inflammatory and structural lesions in hand osteoarthritis : an outcome measures in rheumatology agreement and reliability study
Alexander Mathiessen
Hilde B. Hammer
Lene Terslev
Marion C. Kortekaas
Maria A. D’Agostino
Ida K. Haugen
George A. Bruyn
Georgios Filippou
Emilio Filippucci
Margreet Kloppenburg
et al.
A1
Journal Article
in
ARTHRITIS CARE & RESEARCH
2022
Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range : OMERACT ultrasound minimal disease study
Jeanette Trickey
Ilfita Sahbudin
Mads Ammitzbøll-Danielsen
Irene Azzolin
Carina Borst
Alessandra Bortoluzzi
George AW Bruyn
Philippe Carron
Coziana Ciurtin
Georgios Filippou
et al.
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2022
2021
Core outcome measurement instrument selection for physical function in hand osteoarthritis using the OMERACT Filter 2.1 process
Féline P.B. Kroon
Désirée van der Heijde
Lara J. Maxwell
Dorcas E. Beaton
Abishek Abishek
Francis Berenbaum
Francisco J. Blanco
Philip G. Conaghan
Krysia Dziedzic
Catherine L. Hill
et al.
A1
Journal Article
in
SEMINARS IN ARTHRITIS AND RHEUMATISM
2021
MRI-based synthetic CT in the detection of structural lesions in patients with suspected sacroiliitis : comparison with MRI
Lennart Jans
Min Chen
Dirk Elewaut
Filip Van den Bosch
Philippe Carron
Peggy Jacques
Ruth Wittoek
Jacob L. Jaremko
Nele Herregods
A1
Journal Article
in
RADIOLOGY
2021
Methotrexate treatment in hand osteoarthritis refractory to usual treatments : a randomised, double-blind, placebo-controlled trial
Stéphanie Ferrero
Ruth Wittoek
Edem Allado
Coralie Cruzel
Eric Fontas
Veronique Breuil
Liana Ziegler
Joel Kremer
Damien Loeuille
Christian H. Roux
A1
Journal Article
in
SEMINARS IN ARTHRITIS AND RHEUMATISM
2021
Topographical analysis of structural lesions between dominant and non-dominant hands in erosive osteoarthritis
Edem Allado
Ruth Wittoek
Eliane Albuisson
Stephanie Ferrero
Bruno Chenuel
Isabelle Chary-Valckenaere
Christian Roux
Damien Loeuille
A1
Journal Article
in
RHEUMATOLOGY INTERNATIONAL
2021
2020
Assessment of structural lesions, synovitis and bone marrow lesions in erosive hand osteoarthritis on MRI (0.3T) compared to the radiographic anatomical Verbruggen-Veys score
Edem Allado
Ruth Wittoek
Stephanie Ferrero
Eliane Albuisson
Isabelle Chary-Valckenaere
Christian Roux
Damien Loeuille
A1
Journal Article
in
PLOS ONE
2020
Correction to: Prevalence of musculoskeletal complaints in urban communities in multi-ethnic Suriname : a cross-sectional study with the COPCORD methodology (stage 1, phase 1 and 2)
N. Ho-A-Tham
Y. Vanlandewijck
L. De Donder
Ruth Wittoek
B. Ting-A-Kee
R. Basantram
W. Dankaerts
Correction
2020
Development of classification criteria for hand osteoarthritis : comparative analyses of persons with and without hand osteoarthritis
Ida K. Haugen
David T. Felson
Abhishek Abhishek
Francis Berenbaum
Sita Bierma-Zeinstra
Tove Borgen
Gabriel Herrero Beaumont
Mariko Ishimori
Helgi Jonsson
Feline P. B. Kroon
et al.
A1
Journal Article
in
RMD OPEN
2020
Etanercept therapy leads to reductions in matrix metalloproteinase-3 in patients with erosive hand osteoarthritis
Féline PB Kroon
Anne C Bay-Jensen
Ruth Wittoek
August Verbruggen
Joseph S Smolen
Margreet Kloppenburg
Roberta Ramonda
A1
Journal Article
in
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
2020
Influence of non-steroidal anti-inflammatory drugs on the inflammatory sonographic features in erosive hand osteoarthritis : an intervention study
Qun Xia Xu
Ruth Wittoek
A2
Journal Article
in
RHEUMATOLOGY ADVANCES IN PRACTICE
2020
Natural disease progression in finger osteoarthritis : results from a 10 year follow-up cohort
Tine Vanhaverbeke
Lisa Pardaens
Ruth Wittoek
A1
Journal Article
in
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
2020
Prevalence of musculoskeletal complaints in urban communities in multi-ethnic Suriname : a cross-sectional study with the COPCORD methodology (stage 1, phase 1 and 2)
N. Ho-A-Tham
Y. Vanlandewijck
L. de Donder
Ruth Wittoek
B. Ting-A-Kee
R. Basantram
W. Dankaerts
A1
Journal Article
in
CLINICAL RHEUMATOLOGY
2020
Responses to 'Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain : a double-blind multicenter randomized placebo controlled three-arm study' : authors’ reply
Yves Henrotin
Anne-Françoise Donneau
Kurt de Vlam
Ruth Wittoek
Frank Luyten
A1
Journal Article
in
ARTHRITIS RESEARCH & THERAPY
2020
2019
Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain : a double-blind multicenter randomized placebo controlled three-arm study
Y. Henrotin
M. Malaise
Ruth Wittoek
K. de Vlam
J.-P. Brasseur
F. P. Luyten
Q. Jiangang
M. Van den Berghe
R. Uhoda
J. Bentin
et al.
A1
Journal Article
in
ARTHRITIS RESEARCH & THERAPY
2019
Diet-induced weight loss alone or combined with exercise in overweight or obese people with knee osteoarthritis : a systematic review and metaanalysis
Michelle Hall
Birgit Castelein
Ruth Wittoek
Patrick Calders
Ans Van Ginckel
A1
Journal Article
in
SEMINARS IN ARTHRITIS AND RHEUMATISM
2019
Efficacy of bio-optimised curcuma extract (FLEXOFYTOL®) for painful knee osteoarthritis : data from copra, a multicenter randomised controlled study
Yves Henrotin
Michel Malaise
Ruth Wittoek
Kurt De Vlam
Jean P Brasseur
Frank Luyten
Q Jiangang
Marthe Van den Berghe
R Uhoda
Jacques Bentin
et al.
C3
Conference
2019
Methotrexate in patients with hand erosive osteoarthritis refractory to usual treatments : a randomized, double-blind, placebo-controlled trial
Stéphanie Ferrero
Ruth Wittoek
Edem Allado
Coralie Cruzel
Véronique Breuil
Liana Euller Ziegler
Damien Damien Loeuille
Christian Roux
Joel Kremer
C3
Conference
2019
Methotrexate in patients with hand osteoarthritis refractory to analgesics : a randomised, double-blind, placebo controlled trial
Stéphanie Ferrero
Ruth Wittoek
Adem Allado
Eric Fontas
Coralie Cruzel
Liana Euller Ziegler
Damien Loeuille
Christian Roux
C3
Conference
2019
Natural disease progression in hand osteoarthritis : results from a Belgian ten-years prospective cohort study
Lisa Pardaens
Tine Vanhaverbeke
Jordy Vander Cruyssen
Ruth Wittoek
C3
Conference
2019
Natural disease progression in hand osteoarthritis : results from a Belgian ten-years prospective cohort study
Lisa Pardaens
Tine Vanhaverbeke
Jordy Vandercruyssen
Ruth Wittoek
C3
Conference
2019
Phase IIa, placebo-controlled, randomised study of lutikizumab, an anti-interleukin-1α and anti-interleukin-1β dual variable domain immunoglobulin, in patients with erosive hand osteoarthritis
Margreet Kloppenburg
Charles Peterfy
Ida K Haugen
Féline Kroon
Su Chen
Li Wang
Wei Liu
Gwen Levy
Roy M Fleischmann
Francis Berenbaum
et al.
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2019
Predictors of radiographic progression in hand osteoarthritis : a ten-years prospective cohort study
Tine Vanhaverbeke
Lisa Pardaens
Ruth Wittoek
C3
Conference
2019
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients
Koen Venken
Peggy Jacques
Céline Mortier
Mark E. Labadia
Tine Decruy
Julie Coudenys
Kathleen Hoyt
Anita L. Wayne
Robert Hughes
Michael Turner
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
Repetitive knee bending and synovitis in individuals at risk of and with knee osteoarthritis : data from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium
Ans Van Ginckel
Ruth Wittoek
Sophie De Mits
Patrick Calders
A1
Journal Article
in
ARTHRITIS CARE & RESEARCH
2019
Report from the Hand Osteoarthritis Working Group at OMERACT 2018 : update on core instrument set development
Ruth Wittoek
Féline PB Kroon
Burak Kundakci
Abhishek Abhishek
Ida K Haugen
Francis Berenbaum
Philip G Conaghan
Mariko L Ishimori
Wilma Smeets
Désirée van der Heijde
et al.
A1
Journal Article
in
JOURNAL OF RHEUMATOLOGY
2019
The influence of non-steroidal anti-inflammatory drugs on inflammatory sonographic features in erosive hand osteoarthritis
Xiaxia Xu
Ruth Wittoek
C3
Conference
2019
Very low prevalence of ultrasound determined tendon abnormalities in healthy subjects throughout the age range : an outcome measures in rheumatology (OMERACT) ultrasound minimal disease study
Jeanette Trickey
Ilfita Sahbudin
Alessandra Bortoluzzi
Annamaria Iagnocco
Carlos Pineda
Cesar Sifuentes-Cantu
Coziana Ciurtin
Cristina Reategui-Sokolova
Daniela Fodor
Esperanza Naredo
et al.
C3
Conference
2019
2018
2018 update of the EULAR recommendations for the management of hand osteoarthritis
Margreet Kloppenburg
Féline PB Kroon
Francisco J Blanco
Michael Doherty
Krysia S Dziedzic
Elsie Greibrokk
Ida K Haugen
Gabriel Herrero-Beaumont
Helgi Jonsson
Ingvild Kjeken
et al.
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2018
Efficacy of bio-optimised curcuma extract (Flexofytol®) for painful knee osteoarthritis : data from COPRA, a multicenter randomised controlled study
Y Henrotin
M Malaise
Ruth Wittoek
K Devlam
J-P Brasseur
F Luyten
Q Jiangang
Marthe Van Den Berghe
R Uhoda
J Bentin
et al.
C3
Conference
2018
Etanercept in patients with inflammatory hand osteoarthritis (EHOA) : a multicentre, randomised, double-blind, placebo-controlled trial
Margreet Kloppenburg
Roberta Ramonda
Klaus Bobacz
Wing-Yee Kwok
Dirk Elewaut
Tom WJ Huizinga
Feline PB Kroon
Leonardo Punzi
Josef S Smolen
Bert Vander Cruyssen
et al.
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2018
Immunoscintigraphic detection of tumour necrosis factor by radiolabelled certolizumab pegol in patients with erosive hand osteoarthritis : a proof-of-concept study
Ruth Wittoek
Philippe Carron
Bieke Lambert
Paulien Meersseman
August Verbruggen
Filip Van den Bosch
Dirk Elewaut
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2018
Nieuwe EULAR-aanbevelingen over de behandeling van osteoartritis van de hand
Tine Vanhaverbeke
Lisa Pardaens
Ruth Wittoek
A2
Journal Article
in
ORTHO RHUMATO (NEDERLANDSE ED.)
2018
Prevalence and risk factors of low back pain in the indigenous population of Galibi in Suriname : a cross-sectional community-based study
NB Ho-A-Tham
B Ting-A-Kee
N Struyf
Ruth Wittoek
Y Vanlandewijck
W Dankaerts
C3
Conference
2018
2017
To be or not to be rheumatologist : survey among Belgian medical students and internal medicine trainees : what do certified rheumatologists think about the current rheumatology training program?
Ruth Wittoek
Herman Mielants
A1
Journal Article
in
CLINICAL RHEUMATOLOGY
2017
2016
Hand-related physical function in rheumatic hand conditions : a protocol for developing a patient-reported outcome measurement instrument
Louise Klokker
Caroline B Terwee
Eva Ejlersen Wæhrens
Marius Henriksen
Sandra Nolte
Gregor Liegl
Margreet Kloppenburg
Rene Westhoven
Ruth Wittoek
Ingvild Kjeken
et al.
A1
Journal Article
in
BMJ OPEN
2016
Translation of clinical problems in osteoarthritis into pathophysiological research goals
Peter M van der Kraan
Francis Berenbaum
Francisco J Blanco
de Bari Cosimo
Floris Lafeber
Ellen Hauge
Adele Higginbottom
Andreea Ioan-Facsinay
John Loughlin
Ingrid Meulenbelt
et al.
A2
Journal Article
in
RMD OPEN
2016
2015
Clinical and radiological factors associated with erosive radiographic progression in hand osteoarthritis
Paulien Meersseman
Celine Van de Vyver
August Verbruggen
Dirk Elewaut
Ruth Wittoek
A1
Journal Article
in
OSTEOARTHRITIS AND CARTILAGE
2015
Sustained response to tocilizumab in a patient with relapsing polychondritis with aortic involvement : a case based review
REBECCA STAEL
Vanessa Smith
Ruth Wittoek
David Creytens
Herman Mielants
A1
Journal Article
in
CLINICAL RHEUMATOLOGY
2015
2014
A challenging case of septic sacroiliitis with psoas involvement
Elke O. Kreps
Vanessa Smith
Herman Mielants
Ruth Wittoek
A1
Journal Article
in
ACTA CLINICA BELGICA
2014
2013
3 T DCE-MRI assessment of synovitis of the interphalangeal joints in patients with erosive osteoarthritis for treatment response monitoring
Lennart Jans
Tineke De Coninck
Ruth Wittoek
VALERIE LAMBRECHT
Wouter Huysse
August Verbruggen
Koenraad Verstraete
A1
Journal Article
in
SKELETAL RADIOLOGY
2013
2012
Predictors of functional impairment and pain in erosive osteoarthritis of the interphalangeal joints: comparison with controlled inflammatory arthritis
Ruth Wittoek
Bert Vander Cruyssen
August Verbruggen
A1
Journal Article
in
ARTHRITIS AND RHEUMATISM
2012
Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints : a double blind, randomised trial on structure modification
August Verbruggen
Ruth Wittoek
Bert Vander Cruyssen
Dirk Elewaut
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2012
2011
Reliability and construct validity of ultrasonography of soft tissue and destructive changes in erosive osteoarthritis of the interphalangeal finger joints: a comparison with MRI
Ruth Wittoek
Lennart Jans
VALERIE LAMBRECHT
Philippe Carron
Koenraad Verstraete
August Verbruggen
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2011
2010
Beyond the scope of erosive osteoarthritis of the interphalangeal finger joints: new insights from epidemiological, clinical and imaging based studies
Ruth Wittoek
August Verbruggen
Dirk Elewaut
Dissertation
2010
Morbid anatomy of 'erosive osteoarthritis' of the interphalangeal finger joints : an optimised scoring system to monitor disease progression in affected joints
August Verbruggen
Ruth Wittoek
Bert Vander Cruyssen
Dirk Elewaut
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2010
Structural and inflammatory sonographic findings in erosive and non-erosive osteoarthritis of the interphalangeal finger joints
Ruth Wittoek
Philippe Carron
August Verbruggen
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2010
2009
Classification models for disease: the effect of associations between markers on calculating the risk for disease by likelihood ratio products
Ruth Wittoek
Filip De Keyser
A Boonen
Kurt de Vlam
Nathan Vastesaeger
Herman Mielants
Bert Vander Cruyssen
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
2009
Clinical assessment in the spondyloarthropathies
Ruth Wittoek
Herman Mielants
A1
Journal Article
in
Advances in Experimental Medicine and Biology
2009
Correlation between FIHOA and AUSCAN and radiographic damage in patients with osteoarthritis of the hands
Ruth Wittoek
August Verbruggen
C3
Conference
2009
Cross-cultural adaptation of the Dutch version of the functional index for hand osteoarthritis (FIHOA)and a study on its construct validity
Ruth Wittoek
Bert Vander Cruyssen
E Maheu
August Verbruggen
A1
Journal Article
in
OSTEOARTHRITIS AND CARTILAGE
2009
2008
Agreement between evidence and Belgian rheumatologists' experience on HLA B27 determination in patients with specific imaging features in ankylosing spondylitis
Ruth Wittoek
Kurt De Vlam
R FRANCOIS
L GOTLIEB
J LENAERTS
Filip Van den Bosch
Herman Mielants
C3
Conference
2008
Agreement between evidence and Belgian rheumatologists' experience on the use of DMARDs for arthritis and/or enthesitis in ankylosing spondylitis
Ruth Wittoek
Kurt De Vlam
R FRANCOIS
L GOTLIEB
J LENAERTS
Filip Van den Bosch
Herman Mielants
C3
Conference
2008
Correlation between FIHOA and AUSCAN and radiographic damage in patients with osteoarthritis of the hands
Ruth Wittoek
August Verbruggen
C3
Conference
2008
Prediction models for disease: The effect of associations between markers on calculating the risk for disease by likelihood ratio products in SpA
Bert Vander Cruyssen
Ruth Wittoek
A BOONEN
Kurt De Vlam
N VASTESAEGER
W NOEL
Herman Mielants
Filip De Keyser
C3
Conference
2008
Spontaneous amelioration in early RA: Role of antibody profiles in predicting decrease of disease activity
Bert Vander Cruyssen
AMM MILTENBURG
Filip Van den Bosch
J HOUBIERS
Ruth Wittoek
AMH BOOTS
Filip De Keyser
C3
Conference
2008
2007
Decrease of disease activity under ineffective therapy in DMARD-naive patients with early rheumatoid arthritis: Role of antibody profiles and carriage of the HLA shared epitope in predicting decrease of disease activity
BERT VANDER CRUYSSEN
AMM MILTENBURG
Filip Van den Bosch
JGA HOUBIERS
Ruth Wittoek
AMH BOOTS
Filip De Keyser
A1
Journal Article
in
JOURNAL OF RHEUMATOLOGY
2007
Osteochondral repair in synovial joints
August Verbruggen
Ruth Wittoek
Sara Groeneboer
Bert Vander Cruyssen
Stefan Goemaere
Dirk Elewaut
A1
Journal Article
in
CURRENT OPINION IN RHEUMATOLOGY
2007