Research Explorer

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Researcher

Ruslan Dmitriev

Publications & Research Data

Awards & Distinctions

138 Results

2026

A novel model to study the impact of gender-affirming therapy on bone in young male mice

Lieve VerlindenSandra Calvo BlancoToke LiekensIngrid StockmansKaren MoermansDieter SchollaertChris VercruysseTom FiersTim ReynsNick Narinx et al.

U Journal Article in Journal of Bone and Mineral Research

Correlating stimulated emission depletion microscopy with fluorescence lifetime imaging microscopy to study the TIE2 protein on kidney glomerular podocytes

Iulia-Aneta DénesIrina OkkelmanHerlinde De KeersmaeckerPieter CornillieRuslan DmitrievWard De Spiegelaere

A1 Journal Article in JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

2025

Androgens differentially modulate glucocorticoid effects on adipose tissue and lean mass

Vera SommersKarel DavidChristine HelsenKaren MoermansIngrid StockmansGabriele FerrariRuslan DmitrievSteve StegenOnno C. MeijerJan Kroon et al.

A1 Journal Article in JOURNAL OF ENDOCRINOLOGY

Assessing the effect of aberrant FOXG1 expression in neural organoids

Nore Van LoonLukas GenbruggeEmiel Van WetterFynn Maximilian GodefroyMichael B VaughanLisa HamerlinckLara ColomboSebastian LeimbacherLies VantommeEsperanza Daal et al.

Assessing the effect of aberrant FOXG1 expression in neural organoids

Nore Van LoonLukas GenbruggeHannelore Lefever PrinzEmiel Van WetterFynn Maximilian GodefroyMichael B VaughanLisa HamerlinckSebastian LeimbacherLara ColomboLies Vantomme et al.

Assessing the effect of aberrant FOXG1 expression in neural organoids

Nore Van LoonLukas GenbruggeEmiel Van WetterFynn Maximilian GodefroyMichael B VaughanLisa HamerlinckLara ColomboSebastian LeimbacherLies VantommeEsperanza Daal et al.

Cell-specific mRNA delivery via nanobody-functionalized lipid nanoparticles

Linglong ChenHans Van Der WekenOlivier ZwaenepoelIrina OkkelmanJustine AelvoetEmma Van DenbergheJan GettemansRuslan DmitrievBruno De GeestEric Cox et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Fluorescence Lifetime Imaging Microscopy (FLIM) visualizes internalization and biological impact of nanoplastics in live intestinal organoids

Irina OkkelmanHang ZhouSergey M. BorisovAngela DebruyneAustin E.Y.T. LefebvreMarcello Leomil ZoccolerLinglong ChenBert DevriendtRuslan Dmitriev

Front cover : optoelectronic properties and fluorescence lifetime imaging application of donor‐acceptor dyads derived from 2,6‐dicarboxyBODIPY (Chem. Eur. J. 10/2025)

Aimee SheehanIrina OkkelmanGeoffrey GroslambertChristophe BucherRuslan DmitrievMikhail A. Filatov

Lack of biochemical signalling in GelMA leads to polarity reversion in intestinal organoids independent from mechanoreciprocity

Lenie VanhoveThomas Van GansbekeBert DevriendtRuben Van der MeerenRuslan DmitrievIrina Okkelman

A1 Journal Article in JOURNAL OF TISSUE ENGINEERING

Optoelectronic properties and fluorescence lifetime imaging application of donor‐acceptor dyads derived from 2,6‐dicarboxyBODIPY

Aimee SheehanIrina OkkelmanGeoffrey GroslambertChristophe BucherRuslan DmitrievMikhail A. Filatov

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Poly(2-alkyl-2-oxazoline) hydrogels as synthetic matrices for multicellular spheroid and intestinal organoid cultures

Robin VanhoeijenIrina OkkelmanNette RogierTomáš SedlačíkDaniel StöbenerBert DevriendtRuslan DmitrievRichard Hoogenboom

A1 Journal Article in BIOMACROMOLECULES

Towards contrast between tissue biomarkers with single-wavelength dyes : a first NIR-I in vivo FLT multiplex study using the VUB tauCAM

Simone JanssenThomas Van den DriesSevada SahakianThomas LapauwSam FloruLukasz MatuesiakIrina OkkelmanMarcus StroetJeroen De GeeterRuslan Dmitriev et al.

Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM)

Irina OkkelmanHang ZhouSergey BorisovAngela DebruyneAustin LefebvreMarcelo Leomil ZoccolerLinglong ChenBert DevriendtRuslan Dmitriev

A1 Journal Article in LIGHT-SCIENCE & APPLICATIONS

Volumetric bioprinting of the osteoid niche

Jessie DuquesneLaurens ParmentierEdward VermeerschFlora LemaireJung Won SeoRuslan DmitrievSandra Van Vlierberghe

A1 Journal Article in BIOFABRICATION

2024

2D fibrillar osteoid niche mimicry through inclusion of visco-elastic and topographical cues in gelatin-based networks

Laurens ParmentierSophie D'HaeseJessie DuquesneFabrice BrayLouis Van der MeerenAndre SkirtachChristian RolandoRuslan DmitrievSandra Van Vlierberghe

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Assessing the effect of aberrant FOXG1 expression in neural organoids

Nore Van LoonLukas GenbruggeEmiel Van WetterFynn Maximilian GodefroyMichael B VaughanLisa HamerlinckLara ColomboSebastian LeimbacherLies VantommeEsperanza Daal et al.

Assessing the effect of aberrant FOXG1 expression in neural organoids

Nore Van LoonLukas GenbruggeEmiel Van WetterFynn Maximilian GodefroyMichael B VaughanLisa HamerlinckLara ColomboSebastian LeimbacherLies VantommeEsperanza Daal et al.

Bottom‐up extrusion‐based biofabrication of the osteoid niche

Laurens ParmentierSophie D'HaeseNathan CarpentierRuslan DmitrievSandra Van Vlierberghe

A1 Journal Article in MACROMOLECULAR BIOSCIENCE

DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth

Jonathan BarraIsaiah CrosbourneCassandra L. RobergeRamon Bossardi-RamosJanine S. A. WarrenKailie MattesonLing WangFrances Jourd’heuilSergey M. BorisovErin Bresnahan et al.

A1 Journal Article in ONCOGENE

In Vivo fluorescence lifetime imaging : added value for tumor imaging and importance of fluorophore selection

Simone JanssenThomas Van den DriesMarcus StroetSevada SahakianThomas LapauwIrina OkkelmanRuslan DmitrievMaarten KuijkHans IngelbertsSophie Hernot

Live microscopy of multicellular spheroids with the multimodal near-infrared nanoparticles reveals differences in oxygenation gradients

Angela DebruyneIrina OkkelmanNina HeymansCláudio PinheiroAn HendrixMax NobisSergey M. BorisovRuslan Dmitriev

A1 Journal Article in ACS NANO

Mimicking the bone extracellular matrix through a calcium phosphate-containing thiol–ene cross-linked gelatin composite

Laurens ParmentierSophie D'HaeseLouis Van der MeerenAnna SzabóAndre SkirtachRuslan DmitrievJanis LocsSandra Van Vlierberghe

A1 Journal Article in BIOMACROMOLECULES

Navigating the fate of intestinal epithelial cells in the world of nanoplastic pollution via Fluorescence Lifetime Imaging Microscopy (FLIM)

Irina OkkelmanBert DevriendtRuslan Dmitriev

Oxygenation gradients in multicellular spheroids : are they always as expected?

Angela DebruyneIrina OkkelmanSergey M. BorisovRuslan Dmitriev

Production and multi-parameter live cell fluorescence lifetime imaging microscopy (FLIM) of multicellular spheroids

Angela DebruyneGabriele FerrariHang ZhouNore Van LoonNina HeymansIrina OkkelmanRuslan Dmitriev

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Lore BillietHanne JansenMelissa PilleLena BoehmeGuillem Sanchez SanchezLaurenz De CockGlenn GoetgelukEva PascalStijn De MunterLucas Deseins et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Tunable self-referenced molecular thermometers via manipulation of dual emission in platinum(II) pyridinedipyrrolide complexes

Andreas RusseggerSusanne M. FischerAngela DebruyneHelmar WiltscheA. Daniel BoeseRuslan DmitrievSergey M. Borisov

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Unveiling the mystery of the TIE receptors in podocytes

Iulia-Aneta DénesWard De SpiegelaerePieter CornillieRuslan Dmitriev

2023

A comprehensive comparison of different seeding densities and the use of microscaffolds to establish a reproducible protocol for unguided neural organoid differentiation

Nore Van LoonMichael B VaughanRuslan DmitrievSarah Vergult

Balance between the cell viability and death in 3D

Angela DebruyneIrina OkkelmanRuslan Dmitriev

A1 Journal Article in SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Bright and photostable TADF‐emitting zirconium(IV) pyridinedipyrrolide complexes : efficient dyes for decay time‐based temperature sensing and imaging

Andreas RusseggerAngela DebruyneDaniel Carvajal BerrioStefanie FuchsJulia MarziKatja Schenke‐LaylandRuslan DmitrievSergey M. Borisov

A1 Journal Article in ADVANCED OPTICAL MATERIALS

Effect of molar mass and alkyl chain length on the surface properties and biocompatibility of poly(alkylene terephthalate)s for potential cardiovascular applications

Lenny Van DaeleBabs Van de VoordeRobin ColenbierLobke De VosLaurens ParmentierLouis Van der MeerenAndre SkirtachRuslan DmitrievPeter DubruelSandra Van Vlierberghe

A1 Journal Article in JOURNAL OF MATERIALS CHEMISTRY B

Engineering vascularization in bone tissue engineering scaffolds through volumetric bioprinting

Jessie DuquesneLaurens ParmentierRuslan DmitrievSandra Van Vlierberghe

Fluorescence intensity and Fluorescence Lifetime Imaging Microscopies (FLIM) of cell differentiation in the small intestinal organoids using cholera toxin

Irina OkkelmanRuslan Dmitriev

Bookchapter in Intestinal differentiated cells : methods and protocols

Live microscopy of multicellular spheroids with the multi-modal near-infrared nanoparticles reveals differences in oxygenation gradients

Angela DebruyneIrina OkkelmanNina HeymansMax NobisSergey M. BorisovRuslan Dmitriev

Probing organoid metabolism using fluorescence lifetime imaging microscopy (FLIM) : the next frontier of drug discovery and disease understanding

Margarida BarrosoMichael G. MonaghanRaluca NiesnerRuslan Dmitriev

A1 Journal Article in ADVANCED DRUG DELIVERY REVIEWS

Probing tumor spheroid hypoxia using red/near-infrared ratiometric O2-sensitive nanoparticles

Angela DebruyneIrina OkkelmanSergey BorisovRuslan Dmitriev

Role of preconditioning with oxygen and glucose deprivation in promoting differentiation of dental pulp stem cells in 3D culture

Irina OkkelmanWinter VandenbergheRuslan Dmitriev

TIE2 receptor localization in glomerular podocytes using super resolution microscopy and fluorescence lifetime imaging microscopy

Iulia-Aneta DénesIrina OkkelmanHerlinde De KeersmaeckerRuslan DmitrievWard De Spiegelaere

2022

Affordable oxygen microscopy-assisted biofabrication of multicellular spheroids

Irina OkkelmanChris VercruysseAlina V. KondrashinaSergey M. BorisovRuslan Dmitriev

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Electrospinning of poly(decamethylene terephthalate) to support vascular graft applications

Babs Van de VoordeBerna ŞensuLobke De VosRobin ColenbierHavva BaşkanJozefien GeltmeyerLaurens ParmentierLenny Van DaeleRuslan DmitrievLincy Pyl et al.

A1 Journal Article in EUROPEAN POLYMER JOURNAL

Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip

Simone PerottoniNuno G. NetoCesare di NittoRuslan DmitrievManuela T. RaimondiMichael G. Monaghan

Poly(alkylene terephthalate)s for cardiovascular applications : effect of molar mass and alkyl chain length on surface properties and biocompatibility

Lenny Van DaeleBabs Van de VoordeLobke De VosRobin ColenbierLaurens ParmentierLouis Van der MeerenAndre SkirtachRuslan DmitrievSandra Van VlierberghePeter Dubruel

2021

Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip

Simone PerottoniNuno G NetoCesare di NittoRuslan DmitrievManuela TeresaMichael Monaghan

A1 Journal Article in LAB ON A CHIP

Luminescence lifetime imaging of three-dimensional biological objects

Ruslan DmitrievXavier IntesMargarida M. Barroso

A1 Journal Article in JOURNAL OF CELL SCIENCE

MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity

Arne PeirsmanEva BlondeelTasdiq AhmedJasper AnckaertDominique AudenaertTom BoterbergKrisztina BuzasNeil CarragherGastone CastellaniFlávia Castro et al.

A1 Journal Article in NATURE METHODS

2020

A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

Irina A. OkkelmanNuno NetoDmitri B. PapkovskyMichael G. MonaghanRuslan Dmitriev

A1 Journal Article in REDOX BIOLOGY

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells

Masahiro KawashimaKarim BensaadChristos E. ZoisAlessandro BarberisEsther BridgesSimon WigfieldChristoffer LagerholmRuslan DmitrievMariko TokiwaMasakazu Toi et al.

A1 Journal Article in CANCER & METABOLISM

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells (vol 8, 13, 2020)

Masahiro KawashimaKarim BensaadChristos E. ZoisAlessandro BarberisEsther BridgesSimon WigfieldChristoffer LagerholmRuslan DmitrievMariko TokiwaMasakazu Toi et al.

Estimation of the mitochondrial membrane potential using fluorescence lifetime imaging microscopy

IrMa A. OkkelmanDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in CYTOMETRY PART A

Evaluation of Ebselen-azadioxatriangulenium as redox-sensitive fluorescent intracellular probe and as indicator within a planar redox optode

Klaus KorenNina Katharina Gravesen SalinasMarco SantellaMaria MosshammerMarie-Caroline MuellerRuslan DmitrievSergey M. BorisovMichael KuhlBo W. Laursen

A1 Journal Article in DYES AND PIGMENTS

Extracellular Ca2+-sensing fluorescent protein biosensor based on a collagen-binding domain

Irina A. OkkelmanRyan McGarrigleShane O’CarrollDaniel Carvajal BerrioKatja Schenke-LaylandJames HynesRuslan Dmitriev

A2 Journal Article in ACS APPLIED BIO MATERIALS

Fatty acid binding protein 7 regulates beige fat-like differentiation of breast cancer cells and thermogenesis

Masahiro KawashimaKarim BensaadChristos ZoisAlessandro BarberisEsther BridgesChristoffer LagerholmRuslan DmitrievMasakazu ToiDmitri B. PapkovskyFrancesca Buffa et al.

Investigating the role of SCO2 in the metabolic adaptation of cancer cells

Alexandre V. ZhdanovOro UchenunuNadezda A. BrazheEvelina NikelshpargDmitry E. AndreevRuslan DmitrievOlga V. SosnovtsevaIvan TopisirovicDmitri B. Papkovsky

Multi-parameter fluorescence lifetime imaging microscopy (FLIM) for imaging metabolism in the intestinal organoids model

Ruslan DmitrievIrina Okkelman

Multiparametric optical bioimaging reveals the fate of epoxy crosslinked biomeshes in the mouse subcutaneous implantation model

Vadim ElaginDaria KuznetsovaEkaterina GrebenikDenis A. ZolotovLeonid IstranovTatiana ZharikovaElena IstranovaAnastasia PolozovaDmitry ReunovAlexandr Kurkov et al.

A1 Journal Article in FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

2019

Background-free fluorescence-decay-time sensing and imaging of PH with highly photostable diazaoxotriangulenium dyes

Irene DalfenRuslan DmitrievGerhard HolstIngo KlimantSergey M. Borisov

A1 Journal Article in ANALYTICAL CHEMISTRY

Chemical cross-linking of xenopericardial biomeshes : a bottom-up study of structural and functional correlations

Ekaterina A. GrebenikLeonid P. IstranovElena V. IstranovaSemyon N. ChurbanovBoris S. ShavkutaRuslan DmitrievNadezhda N. VeryasovaSvetlana L. KotovaAlexander V. KurkovAnatoly B. Shekhter et al.

A1 Journal Article in XENOTRANSPLANTATION

2018

Cellulose-based scaffolds for fluorescence lifetime imaging-assisted tissue engineering

Neil O'DonnellIrina OkkelmanPeter TimashevTatyana I. GromovykhDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in ACTA BIOMATERIALIA

Hybrid biosensing cellulose-based scaffolds for imaging-assisted tissue engineering

Neil O'DonnellIrina A. OkkelmanShannen A. RuanePeter TimashevTatyana I. GromovykhRuslan Dmitriev

Hydrogel-assisted neuroregeneration approaches towards brain injury therapy : a state-of-the-art review

Vladimir A. KornevEkaterina A. GrebenikAnna B. SolovievaRuslan DmitrievPeter S. Timashev

A1 Journal Article in COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

Imaging of oxygen and hypoxia in cell and tissue samples

Dmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Nanoparticle-based fluoroionophore for analysis of potassium ion dynamics in 3D tissue models and in vivo

Bernhard J. MuellerAlexander V. ZhdanovSergey M. BorisovTara FoleyIrina OkkelmanVassiliy TsytsarevQinggong TangReha S. ErzurumluYu ChenHaijiang Zhang et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

New biosensors for metabolic imaging

Neil O'DonnellRuslan DmitrievDmitri Papkovsky

Potassium-sensitive nanoparticles for imaging neural tissues in vitro and in vivo

Ruslan DmitrievB. J. MuellerA. V. ZhdanovS. M. BorisovV. Tsytsarev

Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response

Gary LoughranIrwin JungreisIoanna TzaniMichael PowerRuslan DmitrievIvaylo P. IvanovManolis KellisJohn F. Atkins

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Versatile biosensing scaffold platform based on fluorescent proteins and cellulose

Ruslan DmitrievN. O'DonnellI. A. OkkelmanP. Timashev

2017

Fabrication and handling of 3D scaffolds based on polymers and decellularized tissues

Anastasia ShpichkaAnastasia KorolevaDaria KuznetsovaRuslan DmitrievPeter Timashev

A1 Journal Article in Advances in Experimental Medicine and Biology

In-vitro estimation of O-2 concentrations during corneal cross-linking (CXL) for porcine corneas and collagen type-I gels

Rebecca M. McQuaidMichael MrochenRuslan DmitrievDmitri PapkovskiBrian Vohnsen

Live cell FLIM-PLIM microscopy reveals proliferative and metabolic heterogeneity of intestinal organoids

Ruslan DmitrievT. FoleyD. B. PapkovskyI. A. Okkelman

Live cell imaging of mouse intestinal organoids reveals heterogeneity in their oxygenation

Irina OkkelmanTara FoleyDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in BIOMATERIALS

Live cell microscopy of intestinal organoid oxygenation

Ruslan DmitrievIrina A. OkkelmanTara FoleyDmitri B. Papkovsky

Multi-parametric imaging of hypoxia and cell cycle in intestinal organoid culture

Irina A. OkkelmanTara FoleyDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in Advances in Experimental Medicine and Biology

Multi-parametric live cell microscopy of 3D tissue models preface

Ruslan Dmitriev

Editorial material

Quantitative multi-parametric microscopy analysis of live 3D cell models

Ruslan DmitrievJames JenkinsIrina A. OkkelmanNeil O'Donnell

Steering surface topographies of electrospun fibers : understanding the mechanisms

Gokce YazganRuslan DmitrievVasundhara TyagiJames JenkinsGelu-Marius RotaruMarkus RottmarRene M. RossiClaudio ToncelliDmitri B. PapkovskyKatharina Maniura-Weber et al.

A1 Journal Article in SCIENTIFIC REPORTS

Three-dimensional tissue models and available probes for multi-parametric live cell microscopy : a brief overview

Neil O'DonnellRuslan Dmitriev

A1 Journal Article in Advances in Experimental Medicine and Biology

2016

Development of advanced 3D tissue models and O2 imaging methodologies

James JenkinsRuslan DmitrievDmitri Papkovsky

Evolutionary diversification of the BetaM interactome acquired through co-option of the ATP1B4 gene in placental mammals

Tatyana V. KorneenkoNikolay B. PestovNisar AhmadIrina A. OkkelmanRuslan DmitrievMikhail I. ShakhparonovNikolai N. Modyanov

A1 Journal Article in SCIENTIFIC REPORTS

High-resolution analysis of molecular oxygen in mammalian cell models by phosphorescence lifetime imaging microscopy

Ruslan DmitrievJames JenkinsIrina A. OkkelmanDmitri B. Papkovsky

Metallochelate coupling of phosphorescent Pt-porphyrins to peptides, proteins, and self-assembling protein nanoparticles

Ruslan DmitrievNeil O'DonnellDmitri B. Papkovsky

A1 Journal Article in BIOCONJUGATE CHEMISTRY

Monitoring of O-2 concentrations during Corneal cross-Linking (CXL) by phosphorescence lifetime imaging microscopy (PLIM)

Rebecca M. McQuaidMichael C. MrochenRuslan DmitrievDmitri PapkovskiBrian Vohnsen

Sulforhodamine nanothermometer for multiparametric fluorescence lifetime imaging microscopy

James JenkinsSergey M. BorisovDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in ANALYTICAL CHEMISTRY

Systematic analysis of the PTEN 5 ' leader identifies a major AUU initiated proteoform

Ioanna TzaniIvaylo P. IvanovDmitri E. AndreevRuslan DmitrievKellie A. DeanPavel V. BaranovJohn F. AtkinsGary Loughran

A1 Journal Article in OPEN BIOLOGY

The Ca2+/Mn2+-transporting SPCA2 pump is regulated by oxygen and cell density in colon cancer cells

James JenkinsDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in BIOCHEMICAL JOURNAL

The secretory pathway Ca2+/Mn2+-Atpase SPCA2 regulates Mn2+-dependent cell cycle progression in 3D culture of colon cancer cells

James JenkinsRuslan DmitrievDmitri Papkovsky

Two-acceptor cyanine-based fluorescent indicator for NAD(P)H in tumor cell models

Maksim A. FominRuslan DmitrievJames JenkinsDmitri B. PapkovskyDieter HeindlBurkhard Koenig

A1 Journal Article in ACS SENSORS

Use of fluorescence lifetime imaging microscopy (FLIM) as a timer of cell cycle S phase

Irina A. OkkelmanRuslan DmitrievTara FoleyDmitri B. Papkovsky

A1 Journal Article in PLOS ONE

2015

Imaging of oxygenation in 3D tissue models with multi-modal phosphorescent probes

Dmitri B. PapkovskyRuslan DmitrievSergei Borisov

Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles

Ruslan DmitrievSergey M. BorisovAlina V. KondrashinaJanelle M. P. PakanUjval AnilkumarJochen H. M. PrehnAlexander V. ZhdanovKieran W. McDermottIngo KlimantDmitri B. Papkovsky

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

In vitro ischemia decreases histone H4K16 acetylation in neural cells

Ruslan DmitrievDmitri B. Papkovsky

A1 Journal Article in FEBS LETTERS

Intracellular probes for imaging oxygen concentration : how good are they?

Ruslan DmitrievDmitri B. Papkovsky

A1 Journal Article in METHODS AND APPLICATIONS IN FLUORESCENCE

LOXL2 expression in HCT116 cells under normoxia is regulated by ROS and HIF signaling

Irina OkkelmanRuslan DmitrievAlexander ZhdanovDmitri Papkovsky

Luminescence lifetime imaging microscopy for analysis of oxygen in the cancer cell

Ruslan Dmitriev

Multi-parametric imaging of tumor spheroids with ultra-bright and tunable nanoparticle O-2 probes

Ruslan DmitrievSergey M. BorisovJames JenkinsDmitri B. Papkovsky

Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes

Dmitry E. AndreevPatrick B. F. O'ConnorAlexander V. ZhdanovRuslan DmitrievIvan N. ShatskyDmitri B. PapkovskyPavel V. Baranov

A1 Journal Article in GENOME BIOLOGY

Oxygen-sensing scaffolds for 3-dimensional cell and tissue culture

James JenkinsRuslan DmitrievKarl MortenKieran W. McDermottDmitri B. Papkovsky

A1 Journal Article in ACTA BIOMATERIALIA

Versatile conjugated polymer nanoparticles for high-resolution O-2 imaging in cells and 3D tissue models

Ruslan DmitrievSergey M. BorisovHeiko DuessmannShiwen SunBernhard J. MuellerJochen PrehnVladimir P. BaklaushevIngo KlimantDmitri B. Papkovsky

A1 Journal Article in ACS NANO

2014

Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling

Alexander V. ZhdanovAlicia H. C. WatersAnna V. GolubevaRuslan DmitrievDmitri B. Papkovsky

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Comparison of different techniques for monitoring of mammalian cell respiration

Alina KondrashinaRuslan DmitrievDmitri Papkovsky

Imaging of molecular oxygen at subcellular resolution in mammalian cell culture : from 2D to 3D models

Ruslan DmitrievAlina KondrashinaTara FoleyDmitri Papkovsky

pH-sensitive perylene bisimide probes for live cell fluorescence lifetime imaging

D. AignerRuslan DmitrievS. M. BorisovD. B. PapkovskyI. Klimant

A1 Journal Article in JOURNAL OF MATERIALS CHEMISTRY B

Real-time monitoring of oxygenation in cultured organotypic brain slices

Ruslan DmitrievSergey BorisovAlina KondrashinaJanelle PakanDmitri Papkovsky

Small molecule phosphorescent probes for O-2 imaging in 3D tissue models

Ruslan DmitrievAlina V. KondrashinaKlaus KorenIngo KlimantAlexander V. ZhdanovJanelle M. P. PakanKieran W. McDermottDmitri B. Papkovsky

A1 Journal Article in BIOMATERIALS SCIENCE

Two distinct nuclear localization signals in mammalian MSL1 regulate its function

Ruslan DmitrievNikolay B. PestovMikhail I. ShakhparonovIrina A. Okkelman

A1 Journal Article in JOURNAL OF CELLULAR BIOCHEMISTRY

2013

3D O-2 imaging in the neuronal spheroids

Ruslan DmitrievAlexander V. ZhdanovYvonne M. NolanDmitri B. Papkovsky

Biological detection by optical oxygen sensing

Dmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in CHEMICAL SOCIETY REVIEWS

Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells

Alexander V. ZhdanovRuslan DmitrievAnna V. GolubevaSvetlana A. GavrilovaDmitri B. Papkovsky

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae

Danielle M. TroppensRuslan DmitrievDmitri B. PapkovskyFergal O'GaraJohn P. Morrissey

A1 Journal Article in FEMS YEAST RESEARCH

Imaging of neurosphere oxygenation with phosphorescent probes

Ruslan DmitrievAlexander V. ZhdanovYvonne M. NolanDmitri B. Papkovsky

A1 Journal Article in BIOMATERIALS

Insight into oxygenation levels within 3D cell models and its impact on cell metabolism

Dmitri B. PapkovskyConn CareyKarl MortenRuslan DmitrievJames Hynes

Measurement of cell respiration and oxygenation in standard multichannel biochips using phosphorescent O-2-sensitive probes

Alina V. KondrashinaDmitri B. PapkovskyRuslan Dmitriev

A1 Journal Article in ANALYST

Phosphorescent nanoparticle based probes for imaging and measurement of cellular oxygen

Alina KondrashinaRuslan DmitrievSergey BorisovIngo KlimantAlexander ZhdanovDmitri Papkovsky

Phosphorescent O-2 imaging probes for use in 3D tissue models

Ruslan DmitrievA. V. KondrashinaA. V. ZhdanovD. B. Papkovsky

2012

A phosphorescent nanoparticle-based probe for sensing and imaging of (intra)cellular oxygen in multiple detection modalities

Alina V. KondrashinaRuslan DmitrievSergey M. BorisovIngo KlimantIan O'BrienYvonne M. NolanAlexander V. ZhdanovDmitri B. Papkovsky

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Assessment of cellular oxygen gradients with a panel of phosphorescent oxygen-sensitive probes

Ruslan DmitrievAlexander V. ZhdanovGrzegorz JasionekDmitri B. Papkovsky

A1 Journal Article in ANALYTICAL CHEMISTRY

Assessment of intracellular O-2 gradient on a microplate reader

Ruslan DmitrievAlexander V. ZhdanovGreg JasionekDmitri B. Papkovsky

Availability of key metabolic substrates determines metabolic responses, local oxygenation and HIF-2a stabilization in pheochromocytoma PC12 cells

A. ZhdanovA. WatersA. GolubevaRuslan DmitrievD. Papkovsky

Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling

Alexander V. ZhdanovRuslan DmitrievDmitri B. Papkovsky

A1 Journal Article in BIOSCIENCE REPORTS

Complexes of irIII-octaethylporphyrin with peptides as probes for sensing cellular O2

Klaus KorenRuslan DmitrievSergey M. BorisovDmitri B. PapkovskyIngo Klimant

A1 Journal Article in CHEMBIOCHEM

Histone H4 acetylation at K16 residue and mitochondrial activity in neuronal cells

Ruslan DmitrievAlexander V. ZhdanovDmitri B. Papkovsky

Optical probes and techniques for O-2 measurement in live cells and tissue

Ruslan DmitrievDmitri B. Papkovsky

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Structural evolution and tissue-specific expression of tetrapod-specific second isoform of secretory pathway Ca2+-ATPase

Nikolay B. PestovRuslan DmitrievMaria B. KostinaTatyana V. KorneenkoMikhail I. ShakhparonovNikolai N. Modyanov

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

2011

Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria

Alexander V. ZhdanovRuslan DmitrievDmitri B. Papkovsky

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Cell-penetrating conjugates of coproporphyrins with oligoarginine peptides : rational design and application for sensing intracellular O-2

Ruslan DmitrievHonorata M. RopiakGelii V. PonomarevDmitri V. YashunskyDmitri B. Papkovsky

A1 Journal Article in BIOCONJUGATE CHEMISTRY

Oxygen microscopy and high-throughput analysis of icO(2) by means of cell-penetrating phosphorescent dyes

Ruslan DmitrievA. FercherA. V. ZhdanovD. B. Papkovsky

Rational design and experimental assessment of the new family of intracellular O-2-sensitive probes

Ruslan DmitrievDmitri V. YashunskyHonorata M. RopiakAlexander V. ZhdanovGelii V. PonomarevDmitri B. Papkovsky

Uncoupling effect of bafilomycin A1 on HIF and cell bioenergetics

Ruslan DmitrievAlexander V. ZhdanovDmitri B. Papkovsky

2010

Analysis of cellular function by use of cell-penetrating oxygen sensing probes

Honorata M. RopiakRuslan DmitrievDmitri V. YashunskiGelii V. PonomarevAlexander V. ZhdanovDmitri B. Papkovsky

Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor

Ruslan DmitrievHonorata M. RopiakDmitri V. YashunskyGelii V. PonomarevAlexander V. ZhdanovDmitri B. Papkovsky

A1 Journal Article in FEBS JOURNAL

Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides

Ruslan DmitrievAlexander V. ZhdanovGelii V. PonomarevDmitri V. YashunskiDmitri B. Papkovsky

A1 Journal Article in ANALYTICAL BIOCHEMISTRY

2009

Nuclear transport of protein TTC4 depends on the cell cycle

Ruslan DmitrievIrina A. OkkelmanRoman A. AbdulinMikhail I. ShakhparonovNikolay B. Pestov

A1 Journal Article in CELL AND TISSUE RESEARCH

2008

Structure and function of MYST1 histone acetyltransferase in the interactome of animal cells

Ruslan DmitrievM. I. ShakhparonovN. B. Pestov

A1 Journal Article in BIOCHEMISTRY-MOSCOW

TTC4 provides a functional link between RASSF1C and DNA primase

Ruslan DmitrievMikhail I. ShakhparonovNikolay B. Pestov

2007

Characterization of hampin/MSL1 as a node in the nuclear interactome

Ruslan DmitrievTatyana V. KorneenkoAlexander A. BessonovMikhail I. ShakhparonovNikolai N. ModyanovNikolay B. Pestov

A1 Journal Article in BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of novel protein-protein interactions pertinent to regulation of mammalian hampin/MSL1 and histone acetylase MYST1/MOF

Ruslan DmitrievTatyana V. KorneenkoNikolay B. PestovNikolay N. ModyanovMikhail I. Shakhparonov

2005

A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress

EL ArkbladS TuckNB PestovRuslan DmitrievMB KostinaJ StenvallM TranbergJ Rydstrom

A1 Journal Article in FREE RADICAL BIOLOGY AND MEDICINE