Research Explorer

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Researcher

Ruben De Coen

Awards & Distinctions

14 Results

2024

Combinatorial screening of biscarbamate ionizable lipids identifies a low reactogenicity lipid for lipid nanoparticle mRNA delivery

Emily De LombaerdeYong ChenTingting YeJulie DeckersGiulia MencarelliKim DeswarteHeleen LauwersRuben De CoenSabah KasmiSanne Bevers et al.

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

2020

Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment

Ruben De CoenLutz NuhnChamani PereraMaria Arista-RomeroMartijn RisseeuwAlec FreynRaffael NachbagauerLorenzo AlbertazziSerge Van CalenberghDavid A. Spiegel et al.

A1 Journal Article in BIOMACROMOLECULES

2019

Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells

Annemiek UvynRuben De CoenOlivier De WeverKim DeswarteBart LambrechtBruno De Geest

A1 Journal Article in CHEMICAL COMMUNICATIONS

Efficient innate immune killing of cancer cells triggered by cell-surface anchoring of multivalent antibody-recruiting polymers

Annemiek UvynRuben De CoenMandy GruijsCees W. TukJana De VriezeMarjolein van EgmondBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

Jana De VriezeBenoit LouageKim DeswarteZifu ZhongRuben De CoenSimon Van HerckLutz NuhnCamilla Kaas FrichAlexander N ZelikinStefan Lienenklaus et al.

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic carbohydrate biomaterials for innate immune-engineering

Ruben De CoenBruno De Geest

Water-soluble Withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach

Simon Van HerckBehrouz HassanniaBenoit LouageRaquel Pita CompostizoRuben De CoenWim Vanden BergheTom Vanden BergheBruno De Geest

A1 Journal Article in EUROPEAN POLYMER JOURNAL

2018

Transiently thermoresponsive acetal polymers for safe and effective administration of Amphotericin B as a vaccine adjuvant

Simon Van HerckLien Van HoeckeBenoit LouageLien LybaertRuben De CoenSabah KasmiAaron P Esser-KahnSunil A DavidLutz NuhnBert Schepens et al.

A1 Journal Article in BIOCONJUGATE CHEMISTRY

2017

Tyrosine-triazolinedione bioconjugation as site-selective protein modification starting from RAFT-derived polymers

Stef VandewalleRuben De CoenBruno De GeestFilip Du Prez

A1 Journal Article in ACS MACRO LETTERS

2016

Well-defined polymer-paclitaxel prodrugs by a grafting-from-drug approach

Benoit LouageLutz NuhnMartijn RisseeuwNane VanparijsRuben De CoenIzet KaralicSerge Van CalenberghBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Wohldefinierte polymere Paclitaxel-Prodrugs über eine Grafting-From-Methode ausgehend vom Arzneistoff

Benoit LouageLutz NuhnMartijn RisseeuwNane VanparijsRuben De CoenIzet KaralicSerge Van CalenberghBRUNO DE GEEST

A2 Journal Article in ANGEWANDTE CHEMIE

pH-Degradable mannosylated nanogels for dendritic cell targeting

Ruben De CoenNane VanparijsMartijn RisseeuwLien LybaertBenoit LouageStefaan De KokerVimal Kumar UdhayakumarJohan GrootenLeeanne TaylorNeil Ayres et al.

A1 Journal Article in BIOMACROMOLECULES

2015

Transiently responsive protein–polymer conjugates via a 'grafting-from' RAFT approach for intracellular co-delivery of proteins and immune-modulators

Nane VanparijsRuben De CoenDuchan LaplaceBenoit LouageSamarendra MajiLien LybaertRichard HoogenboomBruno De Geest

A1 Journal Article in CHEMICAL COMMUNICATIONS

2013

Structural modifications of polymethacrylates: impact on thermal behavior and release characteristics of glassy solid solutions

Bart ClaeysRuben De CoenBruno De GeestVictor Retamero De La RosaRichard HoogenboomRobert CarleerPeter AdriaensensJean Paul RemonChris Vervaet

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS