Manage settings
MENU
About this site
In het Nederlands
Home
Researchers
Projects
Organisations
Publications
Infrastructure
Contact
Research Explorer
Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.
Researcher
Roland Contreras
Profile
Projects
Publications
Activities
Awards & Distinctions
152
Results
2020
Off-target glycans encountered along the synthetic biology route toward humanized N-glycans in Pichia pastoris
Bram Laukens
Pieter Jacobs
Katelijne Gheysen
José Martins
Charlot De Wachter
Paul Ameloot
Willy Morelle
Jurgen Haustraete
Jean-Christophe Renauld
Bart Samyn
et al.
A1
Journal Article
in
BIOTECHNOLOGY AND BIOENGINEERING
2020
2010
Alteration of N-glycome in diethylnitrosamine-induced hepatocellular carcinoma mice: a non-invasive monitoring tool for liver cancer
Xue-en Liu
Sylviane Dewaele
Valerie Vanhooren
Yedong Fan
Ling Wang
Jacques Van Huysse
Hui Zhuang
Roland Contreras
Claude Libert
Cuiying Chen
A1
Journal Article
in
LIVER INTERNATIONAL
2010
Altered serum N-glycomics in chronic hepatitis B patients
Hong-Lian Gui
Chung-Fang Gao
Hui Wang
Xue-En Liu
Qing Xie
Sylviane Dewaele
Ling Wang
Hui Zhuang
Roland Contreras
Claude Libert
et al.
A1
Journal Article
in
LIVER INTERNATIONAL
2010
Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate
Pieter Jacobs
M Inan
Nele Festjens
Jurgen Haustraete
Annelies Van Hecke
Roland Contreras
MM Meagher
Nico Callewaert
A1
Journal Article
in
MICROBIAL CELL FACTORIES
2010
2009
Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology
Pieter P. Jacobs
Steven Geysens
Wouter Vervecken
Roland Contreras
Nico Callewaert
A1
Journal Article
in
NATURE PROTOCOLS
2009
N-glycan profiles as tools in diagnosis of hepatocellular carcinoma and prediction of healthy human ageing
Valerie Vanhooren
Xue-En Liu
Claudio Franceschi
Chun-Fang Gao
Claude Libert
Roland Contreras
Cuiying Chen
A1
Journal Article
in
MECHANISMS OF AGEING AND DEVELOPMENT
2009
Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis
Katrien Van Beneden
Ken Coppieters
W Laroy
Filip De Keyser
Ilse Hoffman
Filip Van den Bosch
Bert Vander Cruyssen
Michael Drennan
Peggy Jacques
P Rottiers
et al.
A1
Journal Article
in
ANNALS OF THE RHEUMATIC DISEASES
2009
Serum protein N-glycans profiling for the discovery of potential biomarkers for nonalcoholic steatohepatitis
Cuiying Chen
Hemda Schmilovtz-Weiss
Xue-en Liu
Orit Pappo
Marisa Halpern
Jacqueline Sulkes
Marius Braun
Maya Cohen
Nir Barak
Ran Tur-Kaspa
et al.
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2009
2008
Contribution of galactofuranose to the virulence of the opportunistic pathogen Aspergillus fumigatus
PS SCHMALHORST
S KRAPPMANN
Wouter Vervecken
M ROHDE
M MULLER
GH BRAUS
Roland Contreras
A BRAUN
H BAKKER
FH ROUTIER
A1
Journal Article
in
EUKARYOTIC CELL
2008
Fishing for lectins from diverse sequence libraries by yeast surface display - An exploratory study
Stefan Ryckaert
Nico Callewaert
Pieter Jacobs
Sylviane Dewaele
Isabelle Dewerte
Roland Contreras
A1
Journal Article
in
GLYCOBIOLOGY
2008
Glycosylation and cell surface engineering in Pichia pastoris
Pieter P Jacobs
Nico Callewaert
Roland Contreras
Dissertation
2008
Immunization with an engineered mutant trans-sialidase highly protects mice from experimental Tryponosoma cruzi infection: A vaccine candidate
GH FONTANELLA
Kristof De Vusser
Wouter Laroy
L DAURELIO
AL NOCITO
S REVELLI
Roland Contreras
A1
Journal Article
in
VACCINE
2008
Over-expression of heat shock protein 70 in mice is associated with growth retardation, tumor formation, and early death
Valerie Vanhooren
Xue-En Liu
Liesbeth Desmyter
Ye-Dong Fan
Lieve Vanwalleghem
Wim Van Molle
Sylviane Dewaele
Marleen Praet
Roland Contreras
Claude Libert
et al.
A1
Journal Article
in
REJUVENATION RESEARCH
2008
Pichia surface display: display of proteins on the surface of glycoengineered Pichia pastoris strains
Pieter Jacobs
Stefan Ryckaert
Steven Geysens
Kristof De Vusser
Nico Callewaert
Roland Contreras
A1
Journal Article
in
BIOTECHNOLOGY LETTERS
2008
2007
Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy
H KOGELBERG
B TOLNER
SK SHARMA
MW LOWDELL
U QURESHI
M ROBSON
T HILLYER
RB PEDLEY
Wouter Vervecken
Roland Contreras
et al.
A1
Journal Article
in
GLYCOBIOLOGY
2007
Dependence of neurotrophic factor activation of Trk tyrosine kinase receptors on cellular sialidase
A WORONOWICZ
SR AMITH
Kristof De Vusser
Wouter Laroy
Roland Contreras
S BASTA
MR SZEWCZUK
A1
Journal Article
in
GLYCOBIOLOGY
2007
From laboratory to Phase I/II cancer trials with recombinant biotherapeutics
B TOLNER
L SMITH
T HILLYER
J BHATIA
P BECKETT
L ROBSON
SK SHARMA
N GRIFFIN
Wouter Vervecken
Roland Contreras
et al.
A1
Journal Article
in
EUROPEAN JOURNAL OF CANCER
2007
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
HJ PEL
JH DE WINDE
DB ARCHER
PS DYER
G HOFMANN
PJ SCHAAP
G TURNER
RP DE VRIES
R ALBANG
K ALBERMANN
et al.
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2007
Glycoprofiling by DNA sequence-aided fluorophore-assisted carbohydrate electrophoresis: new opportunities in diagnosing and following disease
Wouter Laroy
Roland Contreras
Bookchapter
in
BioArrays: From Basics to Diagnostics
2007
Identifying genes that extend life-span using a high throughput screening system
Cuiying Chen
Roland Contreras
Bookchapter
in
Biological Aging: Methods and Protocols
2007
Modification of the N-glycosylation pathway to produce homogeneous human-like glycans using GlycoSwitch plasmids
Wouter Vervecken
Nico Callewaert
Vladimir Kaigorodov
Steven Geysens
Roland Contreras
Bookchapter
in
Pichia Protocols
2007
N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus
Xueen Liu
Liesbeth Desmyter
CF GAO
Wouter Laroy
Sylviane Dewaele
Valerie Vanhooren
L WANG
H ZHUANG
Nico Callewaert
Claude Libert
et al.
A1
Journal Article
in
HEPATOLOGY
2007
N-glycomic changes in serum proteins during human aging
Valerie Vanhooren
Liesbeth Desmyter
Xueen Liu
M CARDELLI
C FRANCESCHI
A FEDERICO
Claude Libert
Wouter Laroy
Sylviane Dewaele
Roland Contreras
et al.
A1
Journal Article
in
REJUVENATION RESEARCH
2007
Nonclassical export pathway: overexpression of NCE102 reduces protein and DNA damage and prolongs lifespan in an SGS1 deficient Saccharomyces cerevisiae
Liesbeth Desmyter
Jan Verstraelen
Sylviane Dewaele
Claude Libert
Roland Contreras
Cuiying Chen
A1
Journal Article
in
BIOGERONTOLOGY
2007
Rating of CCl4-induced rat liver fibrosis by blood serum glycomics
Liesbeth Desmyter
Yedong Fan
Marleen Praet
T JAWORSKI
Wouter Vervecken
Bernard de Hemptinne
Roland Contreras
Cuiying Chen
A1
Journal Article
in
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
2007
Trypanosome trans-sialidase mediates neuroprotection against oxidative stress, serum/glucose deprivation, and hypoxia-induced neurite retraction in Trk-expressing PC12 cells
A WORONOWICZ
SR AMITH
VW DAVIS
P JAYANTH
Kristof De Vusser
Wouter Laroy
Roland Contreras
SO MEAKIN
MR SZEWCZUK
A1
Journal Article
in
GLYCOBIOLOGY
2007
2006
Glycome mapping on DNA sequencing equipment
Wouter Laroy
Roland Contreras
Nico Callewaert
A1
Journal Article
in
NATURE PROTOCOLS
2006
Secretion of functional human enzymes by Tetrahymena thermophila
T WEIDE
L HERRMANN
U BOCKAU
N NIEBUR
I ALDAG
Wouter Laroy
Roland Contreras
A TIEDTKE
MWW HARTMANN
A1
Journal Article
in
BMC BIOTECHNOLOGY
2006
The innovative serum protein N-glycans analysis predicts the extent of hepatic fibrosis in patients with nonalcoholic fatty liver disease
H SCHMILOVITZ-WEISS
Cuiying Chen
Roland Contreras
O PAPPO
M HALPERN
J SULKES
M BRAUN
M COHEN
N BARAK
R TUR-KASPA
et al.
C3
Conference
2006
2005
Cloning and characterization of the glucosidase II alpha subunit gene of Trichoderma reesei: a frameshift mutation results in the aberrant glycosylation profile of the hypercellulolytic strain Rut-C30
Steven Geysens
T PAKULA
J UUSITALO
Isabelle Dewerte
M PENTTILA
Roland Contreras
A1
Journal Article
in
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2005
Development of a S-cerevisiae whole cell biocatalyst for in vitro sialylation of oligosaccharides
Stefan Ryckaert
Vera Martens
Kristof De Vusser
Roland Contreras
A1
Journal Article
in
JOURNAL OF BIOTECHNOLOGY
2005
Glycoprofiling of N-linked serum protein: an aging biomarker?
Cuiying Chen
L DESMYTER
W VAN MOLLE
Wouter Laroy
Annelies Van Hecke
Sylviane Dewaele
A FEDERICO
Claude Libert
Roland Contreras
C3
Conference
2005
Human antimicrobial peptides: defensins, cathelicidins and histatins
Kris De Smet
Roland Contreras
A1
Journal Article
in
BIOTECHNOLOGY LETTERS
2005
Independent validation and comparison with fibroscan, fibrotest and liver biopsy of clinical glycomics for the non invasive assessment of liver fibrosis in chronic hepatitis C
L CASTERA
Annelies Van Hecke
P TRIMOULET
Nico Callewaert
P COUZIGOU
V DE LEDINGHEN
Roland Contreras
Wouter Laroy
C3
Conference
2005
N-glycan engineering in yeasts and fungi: finally human-like glycosylation
Nico Callewaert
Wouter Vervecken
Steven Geysens
Roland Contreras
Bookchapter
in
Handbook of Carbohydrate Engineering
2005
Old yellow enzyme interferes with Bax-induced NADPH loss and lipid peroxidation in yeast
Rieka Reekmans
Kris De Smet
Cuiying Chen
P VAN HUMMELEN
Roland Contreras
A1
Journal Article
in
FEMS YEAST RESEARCH
2005
2004
Bax-induced cell death in Candida albicans
Kris De Smet
Ines Eberhardt
Rieka Reekmans
Roland Contreras
A1
Journal Article
in
YEAST
2004
DSA-FACE: high-throughput analysis of the N-glycans of NS0-cell secreted antibodies
Lieselot Defrancq
Nico Callewaert
J ZHU
Wouter Laroy
Roland Contreras
A2
Journal Article
in
Bioprocess International
2004
Expression of the human ferritin light chain in a frataxin mutant yeast affects ageing and cell death
Liesbeth Desmyter
Sylviane Dewaele
Rieka Reekmans
T NYSTROM
Roland Contreras
Cuiying Chen
A1
Journal Article
in
EXPERIMENTAL GERONTOLOGY
2004
Factors influencing glycosylation of Trichoderma reesei cellulases. I: Postsecretorial changes of the O- and N-glycosylation pattern of Cel7A
Ingeborg Stals
Koen Sandra
Steven Geysens
Roland Contreras
Jozef Van Beeumen
Marc Claeyssens
A1
Journal Article
in
GLYCOBIOLOGY
2004
HSAbodies: A new class of engineered antibody-based molecules for targeting cancer
A HUHALOV
C GRAFF
KD WITTRUP
B TOLNER
RB PEDLEY
Wouter Vervecken
Roland Contreras
RHJ BEGENT
KA CHESTER
C3
Conference
2004
In vivo synthesis of mammalian-like, hybrid-type N-glycans in Pichia pastoris
Wouter Vervecken
Vladimir Kaigorodov
Nico Callewaert
Steven Geysens
Kristof De Vusser
Roland Contreras
A1
Journal Article
in
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2004
Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics
Nico Callewaert
Hans Van Vlierberghe
Annelies Van Hecke
Wouter Laroy
Joris Delanghe
Roland Contreras
A1
Journal Article
in
NATURE MEDICINE
2004
Role of oxidative phosphorylation in histatin 5-induced cell death in Saccharomyces cerevisiae
Kris De Smet
Rieka Reekmans
Roland Contreras
A1
Journal Article
in
BIOTECHNOLOGY LETTERS
2004
The bud scar-based screening system for hunting human genes extending life span
Cuiying Chen
Roland Contreras
A1
Journal Article
in
STRATEGIES FOR ENGINEERED NEGLIBLE SENESCENCE: WHY GENUINE CONTROL OF AGING MAY BE FORESEEABLE
2004
Total serum protein N-glycome profiling on a capillary electrophoresis-microfluidics platform
Nico Callewaert
Roland Contreras
L MITNIK-GANKIN
L CAREY
P MATSUDAIRA
D EHRLICH
A1
Journal Article
in
ELECTROPHORESIS
2004
Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation
A WORONOWICZ
Kristof De Vusser
Wouter Laroy
Roland Contreras
SO MEAKIN
GM ROSS
MR SZEWCZUK
A1
Journal Article
in
GLYCOBIOLOGY
2004
2003
A high-throughput screening system for genes extending life-span
Cuiying Chen
Sylviane Dewaele
Bart Braeckman
Liesbeth Desmyter
Jan Verstraelen
Gaetan Borgonie
Jacques Vanfleteren
Roland Contreras
A1
Journal Article
in
EXPERIMENTAL GERONTOLOGY
2003
Increased fucosylation and reduced branching of serum glycoprotein N-glycans in all known subtypes of congenital disorder of glycosylation I
Nico Callewaert
E SCHOLLEN
A VANHECKE
J JAEKEN
G MATTHIJS
Roland Contreras
A1
Journal Article
in
GLYCOBIOLOGY
2003
2002
Non-pathogenic trypanosomatid protozoa as a platform for protein research and production.
R BREITLING
S KLINGNER
Nico Callewaert
R PIETRUCHA
A GEYER
G EHRLICH
R HARTUNG
A MULLER
Roland Contreras
SM BEVERLEY
et al.
A1
Journal Article
in
PROTEIN EXPRESSION AND PURIFICATION
2002
Novel tools for the study of class I alpha-mannosidases: a chromogenic substrate and a substrate-analog inhibitor.
Tom Desmet
Wim Nerinckx
Ingeborg Stals
Nico Callewaert
Roland Contreras
Marc Claeyssens
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2002
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line.
PJ REEVES
Nico Callewaert
Roland Contreras
HG KHORANA
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2002
Use of a meltable polyacrylamide matrix for sodium dodecyl sulfate-polyacrylamide gel electrophoresis in a procedure for N-glycan analysis on picomole amounts of glycoproteins.
Nico Callewaert
Wouter Vervecken
A VAN HECKE
Roland Contreras
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
2002
2001
An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans.
MD DE BACKER
B NELISSEN
Marc Logghe
Jasmine Viaene
I LOONEN
S VANDONINCK
R DE HOOGT
S DEWAELE
FA SIMONS
P VERHASSELT
et al.
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2001
Characterization of sialyltransferase mutants using surface plasmon resonance.
Wouter Laroy
Paul Ameloot
Roland Contreras
A1
Journal Article
in
GLYCOBIOLOGY
2001
Trichoderma reesei alpha-1,2-mannosidase: Structural basis for the cleavage of four consecutive mannose residues.
Filip Van Petegem
H CONTRERAS
Roland Contreras
Jozef Van Beeumen
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2001
Ultrasensitive profiling and sequencing of N-linked oligosaccharides using standard DNA-sequencing equipment.
Nico Callewaert
Steven Geysens
P MOLEMANS
Roland Contreras
A1
Journal Article
in
GLYCOBIOLOGY
2001
Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-alpha-D-mannosidase for N-glycan engineering in Pichia pastoris.
Nico Callewaert
Wouter Laroy
H CADIRGI
Steven Geysens
Xavier Saelens
Willy Min Jou
Roland Contreras
A1
Journal Article
in
FEBS LETTERS
2001
2000
Cloning and expression of cytokine genes
Wim Declercq
Marc Logghe
Walther Fiers
Roland Contreras
Bookchapter
in
Cytokine molecular biology : a practical approach
2000
Cloning of Trypanosoma cruzi trans-sialidase and Expression in Pichia pastoris.
Wouter Laroy
Roland Contreras
A1
Journal Article
in
PROTEIN EXPRESSION AND PURIFICATION
2000
MET15 as a visual selection marker for Candida albicans.
Jasmine Viaene
P TIELS
Marc Logghe
S DEWAELE
Wim Martinet
Roland Contreras
A1
Journal Article
in
YEAST
2000
Molecular cloning and enzymatic characterization of a Trichoderma reesei 1,2-alpha-D-mannosidase.
Marleen Maras
Nico Callewaert
Kathleen Piens
Marc Claeyssens
Wim Martinet
S DEWAELE
H CONTRERAS
I DEWERTE
M PENTTILA
Roland Contreras
A1
Journal Article
in
JOURNAL OF BIOTECHNOLOGY
2000
PCR-and ligation-mediated synthesis of split-marker cassettes with long flanking homology regions for gene disruption in Candida albicans.
R DE HOOGT
WHML LUYTEN
Roland Contreras
MD DE BACKER
A1
Journal Article
in
BIOTECHNIQUES
2000
Single allele knock-out of Candida albicans CGT1 leads to unexpected resistance to hygromycin B and elevated temperature.
MD DE BACKER
RA DE HOOGT
G FROYEN
FC ODDS
F SIMONS
Roland Contreras
W LUYTEN
A1
Journal Article
in
MICROBIOLOGY-UK
2000
1999
Bax-induced cell death in Pichia pastoris.
Wim Martinet
D VAN DEN PLAS
Hilda Raes
Rieka Reekmans
Roland Contreras
A1
Journal Article
in
BIOTECHNOLOGY LETTERS
1999
Filamentous fungi as production organisms for glycoproteins of bio-medical interest.
Marleen Maras
I VAN DIE
Roland Contreras
CAMJJ VAN DEN HONDEL
A1
Journal Article
in
GLYCOCONJUGATE JOURNAL
1999
Identificatie en karakterisering van cellulaire inhibitoren van NF-kB-afhankelijke genexpressie
Karen Heyninck
Roland Contreras
Rudi Beyaert
Dissertation
1999
In vivo synthesis of complex N-glycans by expression of human N-acetylglucosaminyltransferase I in the filamentous fungus Trichoderma reesei
Marleen Maras
André De Bruyn
Wouter Vervecken
J Uusitalo
M Penttilä
R Busson
Piet Herdewijn
Roland Contreras
A1
Journal Article
in
FEBS LETTERS
1999
Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin.
Xavier Saelens
P VANLANDSCHOOT
Wim Martinet
Marleen Maras
Sabine Neirynck
Roland Contreras
Walther Fiers
Willy Min Jou
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1999
Structure-function analysis of human liver a 2, 6-sialyltransferase.
Wouter Laroy
Marleen Maras
Roland Contreras
Bookchapter
in
Sialobiology and Other Novel Forms of Glycosylation / Edited by Y. Inoue, Y.C. Lee and F.A. Troy II. - Osaka : Gakushin, 1999. - 308 p. - ISBN 4-907773-00-5
1999
The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN.
Karen Heyninck
Dirk De Valck
Wim Vanden Berghe
Wim Van Criekinge
Roland Contreras
Walther Fiers
Guy Haegeman
Rudi Beyaert
A1
Journal Article
in
JOURNAL OF CELL BIOLOGY
1999
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases.
Dirk De Valck
DY JIN
Karen Heyninck
Marc Van De Craen
Roland Contreras
Walther Fiers
KT JEANG
Rudi Beyaert
A1
Journal Article
in
ONCOGENE
1999
Transformation of Candida albicans by electroporation.
MD DE BACKER
D MAES
S VANDONINCK
Marc Logghe
Roland Contreras
W LUYTEN
A1
Journal Article
in
YEAST
1999
Tumoral environment triggers transcript anomalies in established tumors : induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcripts
Pieter Rottiers
Marjory Desmedt
Hans Dooms
Roland Contreras
Johan Grooten
A2
Journal Article
in
NEOPLASIA
1999
1998
Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG-M and the tumor-associated antigen HTgp-175.
Pieter Rottiers
T VERFAILLIE
Roland Contreras
H REVETS
Marjory Desmedt
H DOOMS
Walther Fiers
Johan Grooten
A1
Journal Article
in
INTERNATIONAL JOURNAL OF CANCER
1998
Engineering of the carbohydrate moiety of fungal proteins to a mammalian type
Marleen Maras
A De Bruyn
J Schraml
P Herdewijn
Kathleen Piens
Marc Claeyssens
J Uusitalo
M Penttila
Walther Fiers
Roland Contreras
Bookchapter
in
Carbohydrates from Trichoderma reesei and other microorganisms : structures, biochemistry, genetics and applications
1998
Evaluation of recombinant A/Victoria/3/75 (H3N2) influenza neuraminidase mutants as potential broad-spectrum subunit vaccines against influenza A.
Wim Martinet
Tom Deroo
Xavier Saelens
Els Beirnaert
Peter Vanlandschoot
Roland Contreras
Walther Fiers
Willy Min Jou
A1
Journal Article
in
ARCHIVES OF VIROLOGY
1998
Identificatie en karakterisering van fosfolipasen en TNF-resistente eiwitten betrokken bij TNF-geïnduceerde celdood en genactivering
Dirk De Valck
Rudi Beyaert
Roland Contreras
Dissertation
1998
Karakterisering van caspasen in een '2 en 3-hybrid'-systeem
Wim Van Criekinge
Rudi Beyaert
Walther Fiers
Roland Contreras
Dissertation
1998
Modification of the protein glycosylation pathway in the methylotrophic yeast Pichia pastoris.
Wim Martinet
Marleen Maras
Xavier Saelens
WM JOU
Roland Contreras
A1
Journal Article
in
BIOTECHNOLOGY LETTERS
1998
NMR techniques in the study of protein-linked carbohydrates
André De Bruyn
J Schraml
Marleen Maras
Roland Contreras
P Herdewijn
C1
Conference
1998
Protein secretion and glycosylation in Trichoderma
G PALAMARCZYK
Marleen Maras
Roland Contreras
J KRUSZEWSKA
[0-9]{2}
1998
1997
A radioactive assay for sialyltransferase activity using 96-well multiscreen filtration plates.
Wouter Laroy
Marleen Maras
Walther Fiers
Roland Contreras
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
1997
A versatile NMR technique for the identification of phosphorylation sites in oligosaccharides
J Schraml
André De Bruyn
Roland Contreras
Piet Herdewijn
A1
Journal Article
in
JOURNAL OF CARBOHYDRATE CHEMISTRY
1997
Hadamard 1D 1H TOCSY and its application to oligosaccharides
J Schraml
H van Halbeek
André De Bruyn
Roland Contreras
Marleen Maras
Piet Herdewijn
A1
Journal Article
in
MAGNETIC RESONANCE IN CHEMISTRY
1997
In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides - Evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei.
Marleen Maras
Xavier Saelens
Wouter Laroy
K PIENS
Marc Claeyssens
Walther Fiers
Roland Contreras
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1997
In vitro conversion of the conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides. Evidence for iV-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei
M MARAS
X SAELENS
Wouter Laroy
Kathleen Piens
Marc Claeyssens
Walther Fiers
Roland Contreras
A2
Journal Article
in
Eur. J. Biochem., 2 45, 617-625
1997
Isolation and analysis of functional homologues of the secretion-related SAR1 gene of Saccharomyces cerevisiae from Aspergillus niger and Trichoderma reesei.
G VELDHUISEN
M SALOHEIMO
MA FIERS
PJ PUNT
Roland Contreras
M PENTTILA
CAMJJ VANDENHONDEL
A1
Journal Article
in
MOLECULAR AND GENERAL GENETICS
1997
NMR evidence for a novel asparagine-linked oligosaccharide on cellobiohydrolase I from Trichoderma reesei RUTC 30
André De Bruyn
Marleen Maras
J. Schraml
Piet Herdewijn
Roland Contreras
A1
Journal Article
in
FEBS LETTERS
1997
Protection of mice against a lethal influenza challenge by immunization with yeast-derived recombinant influenza neuraminidase.
Wim Martinet
Xavier Saelens
Tom Deroo
Sabine Neirynck
Roland Contreras
Willy Min Jou
Walther Fiers
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1997
Structural characterization of N-linked oligosaccharides from cellobiohydrolase I secreted by the filamentous fungus Trichoderma reesei RUTC30
Marleen Maras
André De Bruyn
J Schraml
Piet Herdewijn
Marc Claeyssens
Walther Fiers
Roland Contreras
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1997
1996
A20, an inhibitor of cell death, self-associates by its zinc finger domain.
Dirk De Valck
Karen Heyninck
Wim Van Criekinge
Roland Contreras
Rudi Beyaert
Walther Fiers
A1
Journal Article
in
FEBS LETTERS
1996
1995
Cloning and expression of cytokine genes
Roland Contreras
Jan Demolder
Walther Fiers
Bookchapter
in
Cytokines : a practical approach
1995
ENGINEERING OF THE CARBOHYDRATE MOIETY OF FUNGAL GLYCOPROTEINS TO A MAMMALIAN TYPE.
M MARAS
Walther Fiers
Roland Contreras
A1
Journal Article
in
PROTEIN ENGINEERING
1995
PROTEIN-PRODUCTION BY THE FILAMENTOUS FUNGUS TRICHODERMA-REESEI - SECRETION OF ACTIVE ANTIBODY MOLECULES.
E Nyyssonen
Jan Demolder
Roland Contreras
S Keranen
M Penttila
A1
Journal Article
in
CANADIAN JOURNAL OF BOTANY-REVUE CANADIENNE DE BOTANIQUE
1995
1994
COMPLETE DNA-SEQUENCE OF YEAST CHROMOSOME-II.
H FELDMANN
M AIGLE
G ALJINOVIC
B ANDRE
MC BACLET
C BARTHE
A BAUR
AM BECAM
N BITEAU
E BOLES
et al.
A1
Journal Article
in
EMBO JOURNAL
1994
Human interferon-beta, expressed in Saccharomyces cerevisiae, is predominantly directed to the vacuoles. Influence of modified co-expression of secretion factors and chaperones
Jan Demolder
Walther Fiers
Roland Contreras
A1
Journal Article
in
JOURNAL OF BIOTECHNOLOGY
1994
PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE (PRS) - A NEW GENE FAMILY IN SACCHAROMYCES-CEREVISIAE.
AT CARTER
A NARBAD
BM PEARSON
KF BECK
B BAUM
M LOGGHE
Roland Contreras
M SCHWEIZER
A1
Journal Article
in
YEAST
1994
SEQUENCE-ANALYSIS AND EXPRESSION STUDIES OF A GENE ENCODING A NOVEL SERINE PLUS ALANINE-RICH PROTEIN IN TRICHODERMA-HARZIANUM.
GH GOLDMAN
V VASSEUR
Roland Contreras
Marc Van Montagu
A1
Journal Article
in
GENE
1994
THE 2 GENES ENCODING YEAST RIBOSOMAL-PROTEIN S8 RESIDE ON DIFFERENT CHROMOSOMES, AND ARE CLOSELY LINKED TO THE HSP70 STRESS PROTEIN GENE-SSA3 AND GENE-SSA4.
M LOGGHE
Francis Molemans
Walther Fiers
Roland Contreras
A1
Journal Article
in
YEAST
1994
The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp7O stress protein genes SSA3 and SSA4.
Marc Logghe
Francis Molemans
Walther Fiers
Roland Contreras
A2
Journal Article
in
YEAST
1994
1993
A nucleotide substitution in one of the beta-tubulin genes of Trichoderma viride confers resistance to the antimitotic drug methyl benzimidazole-2-yl-carbamate
GH Goldman
Wim Temmerman
D Jacobs
Roland Contreras
Marc Van Montagu
A Herrera Estrella
A1
Journal Article
in
MOLECULAR AND GENERAL GENETICS
1993
Phenotypic effects in Saccharomyces cerevisiae after regulated expression of beta-(l,3)-glucanase from Nicotiana plumbaginifolia
Jan Demolder
M De Backer
Walther Fiers
Roland Contreras
A1
Journal Article
in
JOURNAL OF BIOTECHNOLOGY
1993
SECRETION OF HETEROLOGOUS PROTEINS BY ASPERGILLUS-NIGER - PRODUCTION OF ACTIVE HUMAN INTERLEUKIN-6 IN A PROTEASE-DEFICIENT MUTANT BY KEX2-LIKE PROCESSING OF A GLUCOAMYLASE-HIL6 FUSION PROTEIN.
MP BROEKHUIJSEN
IE MATTERN
Roland Contreras
JR KINGHORN
CAMJJ VANDENHONDEL
A1
Journal Article
in
JOURNAL OF BIOTECHNOLOGY
1993
1992
Characterization of the carbohydrate moiety of glycoproteins from different yeast species
Marleen Maras
Jan Demolder
W Hers
Roland Contreras
C3
Conference
1992
Efficient synthesis of secreted murine interleukin-2 by Saccharomyces cerevisiae: Influence of 3'-untranslated regions and codon usage.
Jan Demolder
Walther Fiers
Roland Contreras
A1
Journal Article
in
GENE
1992
Molecular cloning of the imidazoleglycerolphosphate dehydratase gene of Trichoderma harzianum by genetic complementation in Saccharomyces cerevisiae using a direct expression vector
GH Goldman
Jan Demolder
S Dewaele
A Herrara Estrella
Roberto Geremia
Marc Van Montagu
Roland Contreras
A1
Journal Article
in
MOLECULAR AND GENERAL GENETICS
1992
THE ASPERGILLUS-NIGER-NIAD GENE ENCODING NITRATE REDUCTASE - UPSTREAM NUCLEOTIDE AND AMINO-ACID-SEQUENCE COMPARISONS.
SE UNKLES
EI CAMPBELL
PJ PUNT
KL HAWKER
Roland Contreras
AR HAWKINS
CAMJJ VANDENHONDEL
JR KINGHORN
A1
Journal Article
in
GENE
1992
1991
Efficient KEX2-like processing of a glucoamylase-interleukin-6 fusion protein by Aspergillus nidulans and secretion of mature interleukin-6
Roland Contreras
Dirk Carrez
James R Kinghorn
Cees AMJJ van den Hondel
Walther Fiers
A1
Journal Article
in
BIO-TECHNOLOGY
1991
Production and purification of recombinant human interleukin-6 secreted by the yeast Saccharomyces cerevisiae
Yves Guisez
Bernard Tison
Joël Vandekerckhove
Jan Demolder
Guy Bauw
Guy Haegeman
Walther Fiers
Roland Contreras
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1991
The nucleotide sequence of a third cyclophilin-homologous gene from Saccharomyces cerevisiae
L Franco
A Jiménez
Jan Demolder
Francis Molemans
Walther Fiers
Roland Contreras
A1
Journal Article
in
YEAST
1991
1990
Heterologous gene expression by filamentous fungi: secretion of human interleukin-6 by Aspergillus nidulans
Dirk Carrez
Wouter Janssens
Patrick Degrave
Cees AMJJ van den Hondel
James R Kinghorn
Walther Fiers
Roland Contreras
A1
Journal Article
in
GENE
1990
1989
A gene transfer system based on the homologous pyrG gene and efficient expression of bacterial genes in Aspergillus oryzae
Yolanda MJT de Ruiter-Jacobs
Martien Broekhuijsen
Shiela E Unkles
Edward I Campbell
Janes R Kinghorn
Roland Contreras
Peter H Pouwels
Cees AMJJ van den Hondel
A1
Journal Article
in
CURRENT GENETICS
1989
Expression of human and murine interleukin-5 in eukaryotic systems
Jan Tavernier
René Devos
José Van der Heyden
Guido Hauquier
Rita Bauden
Ina Faché
Eric Kawashima
Joël Vandekerckhove
Roland Contreras
Walther Fiers
A1
Journal Article
in
DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY
1989
Improved transformation efficiency of Aspergillus niger using the homologous niaD gene for nitrate reductase
Edward I Campbell
Shiela E Unkles
Janet A Macro
Cees van den Hondel
Roland Contreras
James R Kinghorn
A1
Journal Article
in
CURRENT GENETICS
1989
Transformation of Aspergillus niger with the homologous nitrate reductase gene
SE Unkles
EI Campbell
Dirk Carrez
C Grieve
Roland Contreras
Walther Fiers
CAMJJ Van den Hondel
JR Kinghorn
A1
Journal Article
in
GENE
1989
Transformation of a nitrate reductase deficient mutant of Penicillium chrysogenum with the corresponding Aspergillus niger and A. nidulans niaD genes
Michael P Whitehead
Shiela E Unkles
Martin Ramsden
Edward I Campbell
Sarah Jane Gurr
David Spence
Cess Van den Hondel
Roland Contreras
James R Kinghorn
A1
Journal Article
in
MOLECULAR & GENERAL GENETICS
1989
1987
The 3' untranslated region of the human interferon-β mRNA has an inhibitory effect on translation
V Kruys
M Wathelet
P Poupart
Roland Contreras
Walther Fiers
J Content
G Huez
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
1987
1986
Construction of stable laboratory and industrial yeast strains expressing a foreign gene by integrative transformation using a dominant selection system
JingDong Zhu
Roland Contreras
Walther Fiers
A1
Journal Article
in
GENE
1986
1985
A method for fast and pure DNA elution from agarose gels by centrifugal filtration
JingDong Zhu
Walter Kempenaers
Dominique Van Der Straeten
Roland Contreras
Walther Fiers
A1
Journal Article
in
BIO-TECHNOLOGY
1985
1983
Simian virus 40 mutants carrying extensive deletions in the 72-base-pair repeat region
Dirk Gheysen
André Van De Voorde
Roland Contreras
José Van der Heyden
Fred Duerinck
Walther Fiers
A1
Journal Article
in
JOURNAL OF VIROLOGY
1983
1982
Evidence for the direct involvement of DNA replication origin in synthesis of late SV40 RNA
Roland Contreras
Dirk Gheysen
J Knowland
André Van de Voorde
Walther Fiers
A1
Journal Article
in
NATURE
1982
Simple, efficient in vitro synthesis of capped RNA useful for direct expression of cloned eukaryotic genes
Roland Contreras
Hilde Cheroutre
Wim Degrave
Walther Fiers
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
1982
The human fibroblast and human immune interferon genes and their expression in homologous and heterologous cells
Walther Fiers
Erik Remaut
René Devos
Hilde Cheroutre
Roland Contreras
Dirk Gheysen
Wim Degrave
Patrick Stanssens
Jan Tavernier
Yoichi Taya
et al.
A1
Journal Article
in
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
1982
1981
A simple apparatus for injection of nanoliter quantities into Xenopus laevis oocytes
Roland Contreras
Hilde Cheroutre
Walther Fiers
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
1981
Initiation of transcription by RNA polymerase II in permeable, SV40-infected or noninfected, CV1 cells : evidence for multiple promoters of SV40 late transcription
Roland Contreras
Walther Fiers
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
1981
1979
Asymmetric linker molecules for recombinant DNA constructions
Kjeld E Norris
Dirk Iserentant
Roland Contreras
Walther Fiers
A1
Journal Article
in
GENE
1979
Construction and characterization of a plasmid containing a nearly full-size DNA copy of bacteriophage MS2 RNA
René Devos
John Van Emmelo
Roland Contreras
Walther Fiers
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
1979
Identification of the translocatable element IS1 in a molecular chimera constructed with plasmid pBR322 DNA into which a bacteriophage MS2 DNA copy was inserted by the poly(dA)·Poly(dT) linker method
René Devos
Roland Contreras
John Van Emmelo
Walther Fiers
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
1979
Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the late region of the genome
Roland Contreras
Charles Cole
Paul Berg
Walther Fiers
A1
Journal Article
in
JOURNAL OF VIROLOGY
1979
Total synthesis of a tyrosine suppressor transfer RNA gene, XVI: enzymatic joinings to form the total 207-base pair-long DNA
Takao Sekiya
Tatsuo Takeya
Eugene L Brown
Ramamoorthy Belagaja
Roland Contreras
Hans-Joachim Fritz
Michael J Gait
Robert G Lees
Michael J Ryan
H Gobind Khorana
et al.
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
1979
Total synthesis of a tyrosine suppressor transfer RNA gene, XVII: transcription, in vitro, of the synthetic gene and processing of the primary transcript to transfer RNA
Takao Sekiya
Roland Contreras
Tatsuo Takeya
H Gobind Khorana
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
1979
1978
Complete nucleotide sequence of SV40 DNA
Walther Fiers
Roland Contreras
Guy Haegeman
Raphaël Rogiers
André Van De Voorde
Hugo Van Heuverswyn
Jacqueline Van Herreweghe
Guido Volckaert
Marc Ysebaert
A1
Journal Article
in
NATURE
1978
Nucleotide sequence of the restriction fragment Hind-F-EcoRI1 of Simian-Virus-40 DNA (part of the VP1 gene)
Roland Contreras
André Van De Voorde
Walther Fiers
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1978
1977
Nucleotide sequence of simian virus 40 Hind H restriction fragment
Guido Volckaert
Roland Contreras
E Soeda
André Van de Voorde
Walther Fiers
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
1977
Nucleotide sequence of the restriction fragment Hind F-Eco RI2 of SV40 DNA
Roland Contreras
Guido Volckaert
F Thys
André Van de Voorde
Walther Fiers
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
1977
Overlapping of the VP2-VP3 gene and the VP1 gene in the SV40 genome
Roland Contreras
Raphaël Rogiers
André Van de Voorde
Walther Fiers
A1
Journal Article
in
CELL
1977
1976
Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene
Walther Fiers
Roland Contreras
Fred Duerinck
Guy Haegeman
Dirk Iserentant
Jozef Merregaert
Willy Min Jou
Francis Molemans
Alex Raeymaekers
A Van den Berghe
et al.
A1
Journal Article
in
NATURE
1976
Escherichia coli tyrosine transfer ribonucleic acid genes: nucleotide sequences of their promoters and of the regions adjoining C-C-A ends
Takao Sekiya
Roland Contreras
Hans Küpper
Arthur Landy
H Gobind Khorana
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
1976
The initiation region of the SV40 VP1 gene
André Van de Voorde
Roland Contreras
Raphaël Rogiers
Walther Fiers
A1
Journal Article
in
CELL
1976
1975
A method for the isolation of cytidylate series from ribonuclease T1-oligonucleotides
Roland Contreras
Walther Fiers
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
1975
A-Protein gene of bacteriophage MS2
Walther Fiers
Roland Contreras
Fred Duerinck
Guy Haegeman
Jozef Merregaert
Willy Min Jou
Alex Raeymakers
Guido Volckaert
Marc Ysebaert
Joël Vandekerckhove
et al.
A1
Journal Article
in
NATURE
1975
Promoter-dependent transcription of tRNAITyr genes using DNA fragments produced by restriction enzymes
Hans Küpper
Roland Contreras
Arthur Landy
H Gobind Khorana
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
1975
1973
Bacteriophage MS2 RNA: nucleotide sequence of the end of the A protein gene and the intercistronic region
Roland Contreras
Marc Ysebaert
Willy Min Jou
Walther Fiers
A1
Journal Article
in
NATURE-NEW BIOLOGY
1973
1972
Studies on the bacteriophage MS2: some nucleotide sequences from the RNA-polymerase gene
Roland Contreras
Guido Volckaert
Antoon Vandenberghe
Walther Fiers
Willy Min Jou
A1
Journal Article
in
FEBS LETTERS
1972
1971
A new method for partial digestion useful for sequence analysis of polynucleotides
Roland Contreras
Walther Fiers
A1
Journal Article
in
FEBS LETTERS
1971
Position of the first initiation codon in the RNA of bacteriophages MS2 and R17
R. De Wachter
A. Vandenberghe
J. Merregaert
Roland Contreras
Walther Fiers
C3
Conference
1971
Recent progress in the sequence determination of bacteriophage MS2 RNA
Walther Fiers
Roland Contreras
Rupert De Wachter
Guy Haegeman
Jozef Merregaert
Willy Min Jou
Antoon Vandenberghe
A1
Journal Article
in
BIOCHIMIE
1971
Studies on the bacteriophage MS2 nucleotide sequence of a 3′-terminal fragment (n = 104)
Roland Contreras
Antoon Vandenberghe
Willy Min Jou
Rupert De Wachter
Walther Fiers
A1
Journal Article
in
FEBS LETTERS
1971
Studies on the bacteriophage MS2: the untranslated 5'-terminal nucleotide sequence preceding the first cistron
Rupert De Wachter
Jozef Merregaert
Antoon Vandenberghe
Roland Contreras
Walther Fiers
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
1971
The leader sequence from the 5'-terminus to the A-protein initiation codon in MS2-virus RNA
Rupert De Wachter
Antoon Vandenberghe
Jozef Merregaert
Roland Contreras
Walther Fiers
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
1971
1970
The 3′-terminal nucleotide sequence (n = 16) of bacteriophage MS2 RNA
Willy Min Jou
Roland Contreras
Walther Fiers
A1
Journal Article
in
FEBS LETTERS
1970