Research Explorer

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Researcher

Robrecht Thoonen

Awards & Distinctions

21 Results

2017

Erectile dysfunction in heme-deficient nitric oxide-unresponsive soluble guanylate cyclase knock-in mice

Kelly DecaluwéBart PauwelsCharlotte BoydensRobrecht ThoonenEmmanuel S BuysPeter BrouckaertJohan Van de Voorde

A1 Journal Article in JOURNAL OF SEXUAL MEDICINE

Sensitivity to sevoflurane anesthesia is decreased in mice with a congenital deletion of guanylyl cyclase-1 alpha

Yasuko NagasakaMartin WeplerRobrecht ThoonenPatrick SipsKaitlin AllenJan A GrawVincent YaoSara M BurnsStefan MuensterPeter Brouckaert et al.

A1 Journal Article in BMC ANESTHESIOLOGY

2015

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Robrecht ThoonenAnje CauwelsKelly DecaluwéSandra GeschkaRobert E TainshJoris DelangheTino HochepiedLode De CauwerElke RoggeSofie Voet et al.

A1 Journal Article in NATURE COMMUNICATIONS

2014

Heme-deficient NO-unresponsive sGC knock-in mice: novel aspects of NO sGC signaling in cardiovascular (patho)physiology

Robrecht ThoonenEmmanuel BuysAnje CauwelsKelly DecaluwéSandra GeschkaRobert TainshJoris DelangheTino HochepiedLode De CauwerElke Rogge et al.

Influence of cinaciguat on gastrointestinal motility in apo-sGC mice

Sarah CosynsLeander HuygheRobrecht ThoonenJohannes-Peter StaschPeter BrouckaertRomain Lefebvre

A1 Journal Article in NEUROGASTROENTEROLOGY AND MOTILITY

2013

Heme deficiency of soluble guanylate cyclase induces gastroparesis

Sarah CosynsIngeborg DhaeseRobrecht ThoonenES BuysAnne VralPeter BrouckaertRomain Lefebvre

A1 Journal Article in NEUROGASTROENTEROLOGY AND MOTILITY

2010

Generation and characterization of apo-soluble Guanylate Cyclase mice

Robrecht ThoonenPeter Brouckaert

In vitro and in vivo studies on the importance of the soluble guanylyl cyclase α1 subunit in penile erection

Kelly DecaluwéSofie NimmegeersRobrecht ThoonenEmanuel BuysPeter BrouckaertJohan Van de Voorde

A1 Journal Article in WORLD JOURNAL OF UROLOGY

In vivo experiments using soluble guanylyl cyclase Beta1 his 105 Phe mutant mice: no-vasodilatation and penile erection fully dependent on activation of SGC

Kelly DecaluwéSofie NimmegeersHendrik CoppensRobrecht ThoonenPeter BrouckaertJohan Van de Voorde

In vivo studies elucidating the functional role of soluble guanylyl cyclase (sGC) and its different isoforms in vasodilatation and penile erection

Kelly DecaluwéSofie NimmegeersRobrecht ThoonenPeter BrouckaertJohan Van de Voorde

Studies on the importance of soluble guanylyl cyclase (SGC) isoforms in erectile function using transgenic mice

Kelly DecaluwéSofie NimmegeersRobrecht ThoonenEmmanuel BuysPeter BrouckaertJohan Van de Voorde

2009

In vitro and in vivo studies on the importance of the soluble guanylyl cyclase Alpha 1 subunit in penile erection

Kelly DecaluwéSofie NimmegeersRobrecht ThoonenPeter BrouckaertJohan Van de Voorde

In vitro and in vivo studies on the importance of the soluble guanylyl cyclase α1 subunit in penile erection

Kelly DecaluwéSofie NimmegeersRobrecht ThoonenEmanuel BuysPeter BrouckaertJohan Van de Voorde

Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase-dependent manner

Anje CauwelsEmmanuel S BuysRobrecht ThoonenLisa GearyJoris DelangheSruti ShivaPeter Brouckaert

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Vascular smooth muscle relaxation in soluble guanylyl cyclase beta 1 his 105 phe mutant mice

Johan Van de VoordeSofie NimmegeersKelly DecaluwéRobrecht ThoonenPeter Brouckaert

Vascular smooth muscle relaxation in soluble guanylyl cyclase beta 1 his 105 phe mutant mice

Johan Van de VoordeSofie NimmegeersKelly DecaluwéRobrecht ThoonenPeter Brouckaert

sGCα1β1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models

Emmanuel S BuysAnje CauwelsMichael J RaherJonathan J PasseriIon HobaiSharon M CawleyKristen M RauwerdinkHélène ThibaultPatrick SipsRobrecht Thoonen et al.

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

2008

Functional importance of the sGC isoforms (alpha(1)beta(1) and alpha(2)beta(1)) in vascular smooth muscle relaxation

Sofie NimmegeersPatrick SipsE BUYSRobrecht ThoonenK DECALUWEPeter BrouckaertJohan Van de Voorde

Targeting the NO-cGMP pathway: Phenotyping of NO-insensitive sGC beta 1 H105F knockin mice

Robrecht ThoonenM BUYSPatrick SipsElke RoggeT HOCHEPIEDSofie NimmegeersJV DE VOORDEP BROUCKAER

Vascular smooth muscle relaxation in soluble guanylyl cyclase 1 his 105 phe mutant mice

Sofie NimmegeersKelly DecaluwéRobrecht ThoonenPeter BrouckaertJohan Van de Voorde

Vascular smooth muscle relaxation in soluble guanylyl cyclase beta 1 his 105 phe mutant mice

Sofie NimmegeersKelly DecaluwéRobrecht ThoonenPeter BrouckaertJohan Van de Voorde