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Researcher
Roberta Guagliardo
Profile
Projects
Publications
Activities
Awards & Distinctions
9
Results
2025
Surfactant protein B-derived peptides as endosomal escape enhancers for pulmonary delivery of siRNA
Lore Herman
Roberta Guagliardo
Agata Zamborlin
Qiaoyu Liu
Jesús Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2025
2022
A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
Bram Bogaert
Felix Sauvage
Roberta Guagliardo
Cristina Muntean
[missing] Van Phuc Nguyen
Eline Pottie
Mike Wels
An-Katrien Minnaert
Riet De Rycke
Qiangbing Yang
et al.
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2022
2021
Surfactant protein B promotes cytosolic SiRNA delivery by adopting a virus-like mechanism of action
Roberta Guagliardo
Lore Herman
Jelle Penders
Agata Zamborlin
Herlinde De Keersmaecker
Thijs Van de Vyver
Sandrine Verstraeten
Pieterjan Merckx
Marie-Paule Mingeot-Leclercq
Mercedes Echaide
et al.
A1
Journal Article
in
ACS NANO
2021
2020
Beyond the surface : unraveling the intracellular mechanism behind surfactant protein B (SP-B) mediated siRNA delivery
Roberta Guagliardo
Koen Raemdonck
Stefaan De Smedt
Dissertation
2020
Cationic amphiphilic drugs boost the lysosomal escape of small nucleic acid therapeutics in a nanocarrier-dependent manner
Thijs Van de Vyver
Bram Bogaert
Lynn De Backer
Freya Joris
Roberta Guagliardo
Jelter Van Hoeck
Pieterjan Merckx
Serge Van Calenbergh
Srinivas Ramishetti
Dan Peer
et al.
A1
Journal Article
in
ACS NANO
2020
Lyophilization and nebulization of pulmonary surfactant-coated nanogels for siRNA inhalation therapy
Pieterjan Merckx
Joris Lammens
Gust Nuytten
Bram Bogaert
Roberta Guagliardo
Tania Maes
Chris Vervaet
Thomas De Beer
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2020
2019
Nanocarrier lipid composition modulates the impact of pulmonary surfactant protein B (SP-B) on cellular delivery of siRNA
Roberta Guagliardo
Pieterjan Merckx
Agata Zamborlin
Lynn De Backer
Mercedes Echaide
Jesus Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
PHARMACEUTICS
2019
2018
Pulmonary surfactant and drug delivery : focusing on the role of surfactant proteins
Roberta Guagliardo
Jésus Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2018
Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy
Pieterjan Merckx
Lynn De Backer
Lien Van Hoecke
Roberta Guagliardo
Mercedes Echaide
Pieter Baatsen
Bárbara Olmeda
Xavier Saelens
Jésus Pérez-Gil
Stefaan De Smedt
et al.
A1
Journal Article
in
ACTA BIOMATERIALIA
2018