Research Explorer

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Researcher

Richard de Reuver

Awards & Distinctions

6 Results

2025

ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2α-mediated translational arrest and is required for efficient viral replication

Adwait ParchureMia CesarecAntonija BrautRobert KolmanVlatka IvanisevicMarina CunkoSladana BursacRichard de ReuverAntonija J. BegonjaUmberto Rosani et al.

A1 Journal Article in PLOS PATHOGENS

2024

ADAR1 is a central regulator of the dsRNA response : from A-to-Z RNA

Richard de ReuverJonathan Maelfait

Novel insights into double-stranded RNA-mediated immunopathology

Richard de ReuverJonathan Maelfait

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

2022

ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation

Richard de ReuverSimon VerdonckEvelien DierickJosephine NemegeerEline HessmannSadeem AhmadMaude JansGillian BlanckeFilip Van NieuwerburghAlexander Botzki et al.

A1 Journal Article in NATURE

2021

ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation

Richard de ReuverEvelien DierickBartosz WiernickiKatrien StaesLeen SeysEllen De MeesterTuur MuyldermansAlexander BotzkiBart LambrechtFilip Van Nieuwerburgh et al.

A1 Journal Article in CELL REPORTS

2020

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

Michael DevosGiel TangheBarbara GilbertEvelien DierickMaud VerheirstraetenJosephine NemegeerRichard de ReuverSylvie LefebvreJolien De MunckJan Rehwinkel et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE