Research Explorer

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Researcher

René Chofor

8 Results

2016

Synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphate reductoisomerase inhibitors as antimalarial and antituberculosis agents

René ChoforSerge Van Calenbergh

Targeting an aromatic hotspot in Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate reductoisomerase with β-arylpropyl analogues of fosmidomycin

Sanjeewani SooriyaarachchiRené ChoforMartijn RisseeuwTerese BergforsJenny PouyezCynthia S DowdLouis MaesJohan WoutersT Alwyn JonesSerge Van CalenberghSherry L Mowbray

A1 Journal Article in CHEMMEDCHEM

2015

Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase

René ChoforSanjeewani SooriyaarachchiMartijn RisseeuwTerese BergforsJenny PouyezChinchu JohnyAmanda HaymondAnnelien EveraertCynthia S DowdLouis MaesTom CoenyeAlexander AlexRobin D CouchT Alwyn JonesJohan WoutersSherry L MowbraySerge Van Calenbergh

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of β-substituted fosmidomycin analogues as inhibitors of 1-deoxy-D-xylulose 5-phosphate reductoisomerase

René ChoforSanjeewani SooriyaarachchiMartijn RisseeuwTerese BergforsT Alwyn JonesSherry L MowbraySerge Van Calenbergh

2014

Synthetic fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-D-xylulose 5-phosphate reductoisomerase or Plasmodium falciparum growth in vitro

René ChoforMartijn RisseeuwJenny PouyezChinchu JohnyJohan WoutersCynthia S DowdRobin D CouchSerge Van Calenbergh

A1 Journal Article in MOLECULES

2012

Synthesis of β-analogues of FR900098 as antimalarials

Synthesis of β-analogues of FR900098 as antimalarials

René ChoforMartijn RisseeuwThomas VerbrugghenSerge Van Calenbergh

2010

Synthesis and evaluation of amino-modified α-GalCer analogues

Matthias TrappeniersRené ChoforSANDRINE ASPESLAGHYali LiBruno LinclauDirk M ZajoncDirk ElewautSerge Van Calenbergh

A1 Journal Article in ORGANIC LETTERS