Research Explorer

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Researcher

Renate De Smedt

Awards & Distinctions

8 Results

2024

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette Roels et al.

A1 Journal Article in HAEMATOLOGICA

2023

Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma

Lien ProvezTom PuttemanMattias LandforsJuliette RoelsLindy ReunesSara T'SasWouter Van LoockeBéatrice LintermansStien De ConinckMorgan Thenoz et al.

A1 Journal Article in CANCERS

2022

Direct and indirect anti-leukemic properties of Activity-on-Target interferons for the treatment of T-cell acute lymphoblastic leukemia

Steven GoossensAnje CauwelsTim PietersRenate De SmedtSara T'SasAndré Pedro Pinto De AlmeidaWillem DaneelsPieter Van VlierbergheJan Tavernier

A1 Journal Article in HAEMATOLOGICA

PDGFR-β As a New Therapeutic Target in T-Cell Acute Lymphoblastic Leukemia

Stien De ConinckRenate De SmedtBéatrice LintermansSteven GoossensPieter Van Vlierberghe

2020

Finding the 'key' in leukemia : PIM1 inhibition as a novel therapy in T-cell acute lymphoblastic leukemia

Renate De SmedtPieter Van VlierbergheSteven Goossens

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtJulie MorscioLindy ReunesJuliette RoelsValentina BardelliBéatrice LintermansWouter Van LoockeAfonso AlmeidaLaurence C. CheungRishi S. Kotecha et al.

A1 Journal Article in BLOOD

2019

Targeting steroid resistance in T-cell acute lymphoblastic leukemia

Renate De SmedtJulie MorscioSteven GoossensPieter Van Vlierberghe

A1 Journal Article in BLOOD REVIEWS

2018

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtSofie PeirsJulie MorscioFilip MatthijssensJuliette RoelsLindy ReunesBéatrice LintermansSteven GoossensTim LammensNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA