Research Explorer

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Researcher

Ramesh Guggilla

Publications & Research Data

Awards & Distinctions

14 Results

2024

High rate of detected variants in male PLCZ1 and ACTL7A genes causing failed fertilization after ICSI

Arantxa Cardona BarberánRamesh Reddy GuggillaCora ColenbierEmma Van der VeldenAndrei RybouchkinDominic StoopLuc LeybaertPaul CouckeSofie SymoensAnnekatrien Boel et al.

A1 Journal Article in HUMAN REPRODUCTION OPEN

2023

Reliability of blastomere versus trophectoderm biopsy in preimplantation genetic testing for mitochondrial DNA disorders

Noemi CastelluccioRamesh Reddy GuggillaAndrei RybouchkinDominic StoopSofie SymoensPaul CouckeAnnekatrien BoelBjörn Heindryckx

2021

Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences

Panagiotis StamatiadisAnnekatrien BoelGwenny CosemansMina PopovicBieke BekaertRamesh Reddy GuggillaMaoxing TangPetra De SutterFilip Van NieuwerburghBjörn Menten et al.

A1 Journal Article in HUMAN REPRODUCTION

Digital polymerase chain reaction for assessment of mutant mitochondrial carry-over after nuclear transfer for in vitro fertilization

Olivier TytgatMaoxing TangWillem van SnippenbergAnnekatrien BoelRamesh Reddy GuggillaYannick GansemansMichiel Van HerpSofie SymoensWim TrypsteenDieter Deforce et al.

A1 Journal Article in CLINICAL CHEMISTRY

2020

A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line

Bieke BekaertAnnekatrien BoelLisa De WitteMina PopovicRamesh Reddy GuggillaSwati MishraGwenny CosemansLise TordeursSusana Marina Chuva de Sousa LopesPetra De Sutter et al.

Germline nuclear transfer to overcome mitochondrial disease and female infertility

Maoxing TangAnnekatrien BoelRamesh Reddy GuggillaBieke BekaertPetra De SutterBjörn MentenFrauke Vanden MeerschautDominic StoopPaul CouckeBjörn Heindryckx

2019

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangRamesh Reddy GuggillaYannick GansemansMargot Van der JeughtAnnekatrien BoelMina PopovicPanagiotis StamatiadisMinerva Ferrer BuitragoVanessa ThysRudy Van Coster et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Genome editing by CRISPR-Cas9 reveals that pre-implantation development in the mouse is compromised in Pou5f1-null embryos

Panagiotis StamatiadisAnnekatrien BoelMargot Van der JeughtBieke BekaertRamesh Reddy GuggillaMaoxing TangPetra De SutterPaul CouckeBjörn Heindryckx

Heterozygous mutations in PLCZ1 are associated with fertilization failure after ICSI

Ramesh Reddy GuggillaAnnekatrien BoelMinerva Ferrer BuitragoDavina BontePetra De SutterPaul CouckeBjörn Heindryckx

The use of pronuclear transfer to overcome infertility disorders in mice

Björn HeindryckxAnnekatrien BoelPanagiotis StamatiadisMargot Van der JeughtRamesh Reddy GuggillaDieter DeforceRudy Van CosterPetra De Sutter

2018

Mutations in the sperm-activating factor PLCZ1 causing fertilization failure after ICSI lead to partial hydatidiform moles

Ramesh Reddy GuggillaMinerva Ferrer BuitragoDavina BonteLien DhaenensJ. ParringtonPetra De SutterPaul CouckeBjörn Heindryckx

Polar body transfer in a mouse model to overcome transmission of mitochondrial diseases

Maoxing TangRamesh Reddy GuggillaPanagiotis StamatiadisMinerva Ferrer BuitragoVanessa ThysMargot Van der JeughtPetra De SutterBjörn Heindryckx

Unraveling the causes of failed fertilization after intracytoplasmic sperm injection due to oocyte activation deficiency

Davina BonteRamesh Reddy GuggillaPanagiotis StamatiadisPetra De SutterBjörn Heindryckx

Bookchapter in Reproductomics : the -omics revolution and its impact on human reproductive medicine

2017

Identification of novel mutations in PLCZ1 in two patients with fertilization failure after ICSI

Ramesh Reddy GuggillaMinerva Ferrer Buitrago[missing] AmdaniDavina BonteC. JonesK. CowardPaul CouckePetra De SutterBjörn Heindryckx